Basic Information

Gene Symbol
ZNF526
Assembly
GCA_008042655.1
Location
VNJT01001317.1:2030-4090[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.16 12 6.6 0.2 1 21 332 352 332 353 0.95
2 10 8.4e-06 0.00064 20.1 0.3 1 23 361 383 361 383 0.97
3 10 0.0067 0.51 11.0 1.4 1 23 386 409 386 409 0.92
4 10 1.2e-06 9.5e-05 22.7 0.8 2 23 416 437 415 437 0.98
5 10 3.3e-08 2.5e-06 27.7 1.0 1 23 443 465 443 465 0.98
6 10 4.1e-06 0.00031 21.1 0.6 1 23 471 493 471 493 0.99
7 10 0.00034 0.026 15.0 2.3 1 23 499 521 499 521 0.98
8 10 0.00099 0.076 13.6 0.3 1 23 527 549 527 549 0.98
9 10 0.00022 0.017 15.6 2.8 1 23 555 577 555 577 0.99
10 10 0.00098 0.075 13.6 0.1 1 23 583 605 583 605 0.96

Sequence Information

Coding Sequence
ATGGACATCGATAAGATCTGCTTGACCTGCCTGAGCTCAACGGGTCCGTTTCTATCCATCTATGACAACGGATCGGGTAGCTGTCTGGCCGATATGCTTAGGGAATTCACAAAAACTACGCCGCGTCGCCACGATAATCTGCCCGAGAAAGTGTGTCTCGGCTGTTTGAGTGAAATAAACCACTGCTACACGTTCAAGATCATGTGTGAGAATTCCAGTCGAACTCTGCGCCAATTGCTGCCGAATGCCCTACCCGAGGAGTCTGAGCCGGATAAGGTGTTAACAAAGCAGTCAATGTCCACCAGCGACCAGGCGGTGCAGACGTCCAAGTGGGAGCCGAGCCGTTGCACGGTGACGGAACAAGCGGAGGAAGTGGTCATAGATGACAGCAGCCTCTCCAAGCGGAGGATTTCATTTCACTTGGACGACGGTGACGgtgacggagacggagacggtgAGGGCGAGGGCGAAGGAGAGGAATTCGACTACGAGCTGACCGATGAGCCCATGGAAAAGGCTACCGGCATAATCCTGCAAGTACAGCAAAGCTTGAAAGTAGAAAAGGAGGTTGACTTCACGCAGGCCGATGTCATTTATGAGGGCGATGACAACGACTTGGAACAGCAGATCAGGGAGTGCAATCTGGACATATTCGAGAACGAGGTTGCAGATGTCTCCGTGCCAGCTCAGCCGGTTGCTACGAAAAAAGGCGTCGCTAAACTTcttgtgcagcagcagcaacaggaagGGGAGGAGGAAATTGTTAAACAGGAAGCTCATCCGGCAAAAAAATCCTCTCGTCGGAGGGCAGCTGAAAAACAAGAGCTGCACTCCACGTCGGCTTTGTCGACATCTCCCTCGAAGCAGCTGAGAACTGGATCCAGCCACAGGTCTCTTGCCTCAGTTGCTGCGTCCGCAGCAGCCACCTCGTCCTCCGCGGCTGCAGGAACCAGCCTAGCAGCGGGAGGAGCTGCGCTGGTAGCTGAGCTCAAATACCATTGTGATCGCTGTAATGCTGGCTTTGCATTGGAGAAATCCCTGATTATTCACAAAAGGCAGAACAGCTGCACGAACCGCAATTTCAAGTGTGATGAGTGCGAACGGGTCTTTGTGTCGCCGGATCATCTGGCCGAGCACCGGGCCAATCATGGCGCCCACAACTGTGCGGAATGTGGGTTGAAGTGCGAGTCCAAGGAGCAGCTAGGCAAGCACATGGTTCAGGGCCACAAGCGAAATCTACGCAACCAGTGCAACGTCTGCCAAAAAGTCTTTACCATGCTGTCAACGCTGCGGGACCACATGCGCATCCACACCGGAGAGAAGCCATTTGTGTGCAATATATGCGGGAAGAGCTTCACCCAAAACGCCAATCTGCGCCAGCACAAGCTGCGCCACTCGGAGACAAAGAGCTTCAAGTGCGAGCTGTGCCCGCACTCATTCGTAACCAAGGCGGAGCTAGCTTCTCACGCCCGCACCCACACGGGCGACAAGCCCTTTGAGTGTGAGGTGTGCGCGGCCAGGTTCACCACCAGCTGCTCGCTGGCCAAGCACAAACGCAAGCACACCGGGGAACGGCCCTACGCCTGCGATCTGTGTCCCATGAGGTTCACAGCCCTAAATGTGCTGAAGAACCACCGGAGAACGCATACGGGCGAGCGTCCATATGTGTGCCCCTTCTGCGCGAAGACTTTCACGCAGCGGGGCGACTGCCAGATGCATCAGAGGACCCATCAGGGCGACCGCATCTATATTTGTCCAGTCTGCAACGAGGAGTTCAAAACGATGCCAGAGATGCGGTCGCATTTGTCCGGACACGAGCAGCACGACAAGCGACTGGTGCACTTCACCCTGATAAGCAATAAGGAAAATGGGAGCGGAGCCCTTGAGGATGACTTGAACGAGATGGCTGAGTCGGCGCTGATGATATGA
Protein Sequence
MDIDKICLTCLSSTGPFLSIYDNGSGSCLADMLREFTKTTPRRHDNLPEKVCLGCLSEINHCYTFKIMCENSSRTLRQLLPNALPEESEPDKVLTKQSMSTSDQAVQTSKWEPSRCTVTEQAEEVVIDDSSLSKRRISFHLDDGDGDGDGDGEGEGEGEEFDYELTDEPMEKATGIILQVQQSLKVEKEVDFTQADVIYEGDDNDLEQQIRECNLDIFENEVADVSVPAQPVATKKGVAKLLVQQQQQEGEEEIVKQEAHPAKKSSRRRAAEKQELHSTSALSTSPSKQLRTGSSHRSLASVAASAAATSSSAAAGTSLAAGGAALVAELKYHCDRCNAGFALEKSLIIHKRQNSCTNRNFKCDECERVFVSPDHLAEHRANHGAHNCAECGLKCESKEQLGKHMVQGHKRNLRNQCNVCQKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELASHARTHTGDKPFECEVCAARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCAKTFTQRGDCQMHQRTHQGDRIYICPVCNEEFKTMPEMRSHLSGHEQHDKRLVHFTLISNKENGSGALEDDLNEMAESALMI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00491650;
90% Identity
iTF_00613630;
80% Identity
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