Dbur003995.1
Basic Information
- Insect
- Drosophila burlai
- Gene Symbol
- -
- Assembly
- GCA_008042655.1
- Location
- VNJT01010798.1:2-1182[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 1.2 89 3.9 0.2 1 23 27 49 27 49 0.91 2 12 2.6e-05 0.002 18.6 2.7 2 23 52 73 52 73 0.97 3 12 1e-05 0.00077 19.9 0.2 3 23 81 101 79 101 0.98 4 12 8.3e-08 6.4e-06 26.4 4.1 2 23 108 129 107 129 0.97 5 12 0.75 58 4.5 0.4 5 23 142 160 139 160 0.96 6 12 0.2 15 6.4 5.4 3 23 167 188 165 188 0.93 7 12 0.021 1.6 9.4 0.2 2 23 199 219 198 219 0.96 8 12 8.1e-06 0.00062 20.2 0.4 1 19 225 243 225 247 0.95 9 12 5e-06 0.00039 20.8 0.4 1 23 255 277 255 277 0.98 10 12 1.5e-05 0.0011 19.3 7.6 1 23 283 305 283 306 0.96 11 12 3.2e-05 0.0024 18.3 6.5 1 23 311 333 311 333 0.98 12 12 0.00038 0.029 14.9 6.1 1 23 339 361 339 362 0.96
Sequence Information
- Coding Sequence
- GCCTACAATGAATCAAAGCTGGGCCAGGAGCGCAACAACCTCAGCGAACTGGAGCAGAAGGCCATGGAGAAGTCCATTTTTTTGTGCTACGTCTGCCGCACCGACTTCCCCTCCGTCAAGCTTTACGATGCCCATCTCACCGAGCACCCGGCCGAGTGTTTCACCTGCGGCAAGAAGTTCTACCGCTGGAAGAACTTCTCGCTGCACCTGAAGCGGCACCTGGGCTGGAAGGAGTTCGGCTGTTACGTGTGCGACAAGAAGTTCGTGGTGCGGAGCGCCCTCGTCGAGCACATGCGGATGCACACGGGCCAGACGCCGCTCAAGTGCAAGATATGCGGGAAAAAGTTCAAGCGCTACTCGAATCTGACGCAGCACCGCAAGCGACACACCAAGGTGATGGTGCGGAAGAAGGAGTACGTGTGCCACTGCGGCGAGGTACTGCCCTCAAAGGCGCGCTTCCTCTGGCACAAGGAGACGCACGACTTGAAGCCGAAATGCTGCCCCTATTGCTGTGACAGATTCGTGCACGCCAACTCGCTGCGCCGCCACATACGTCTGGCGCACTCGGACAAGTTTGACTACGCCGAGCCGATGGAGTGTCCGATGTGCAAGCAGATCTTCGCCAAGACATCGATCAAGGCCCACATGGCGACGCACTCGACGGAGCCGCAGTACGACTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATCCACTCGTGGGTCCACGCCAATCGGACGGCCAAGCCCTTCAAGTGCGAGTACTGCCCGAAGGCGTTTGTGCGCGAGCTGGACTTCAAGAACCACATCAACGCGCACAAGCAGATCAAGCCGTACACGTGCGAGTACTGCGGCTGCAAGTTCATCCGCAAGTACAACTACATGCGGCATCGTCGCGAGCACCACGGCACCAAGAAGTTCACCTGCGACCAGTGCGACAAGTCCTTCCATCGCCACTACTATCTGATCGAGCACCGGCGCATGCATACCGGCGAGCGGCCGTTCACCTGCACCATTTGCGGCAAGAGCTCCACCACCAAGACCAACCACAACAAGCATCTGAAGATCCACCACTCGCGCGACCCCTTCACAGTGGAGGTCTAA
- Protein Sequence
- AYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKVMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTEPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00992019;
- 90% Identity
- iTF_00892081;
- 80% Identity
- -