Dbun004206.1
Basic Information
- Insect
- Drosophila bunnanda
- Gene Symbol
- -
- Assembly
- GCA_008042815.1
- Location
- VNKE01003902.1:13261-15927[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.066 4.7 7.8 5.9 3 23 267 287 265 287 0.96 2 12 0.0011 0.081 13.3 0.5 1 23 293 318 293 318 0.94 3 12 0.0066 0.47 10.9 1.7 1 23 325 350 325 350 0.93 4 12 0.00026 0.018 15.3 1.9 1 23 362 384 362 384 0.98 5 12 2.2e-06 0.00016 21.8 0.2 1 23 391 413 391 413 0.98 6 12 0.0064 0.46 10.9 0.1 1 23 419 441 419 441 0.98 7 12 0.0063 0.44 11.0 4.0 1 23 447 470 447 470 0.98 8 12 0.0085 0.6 10.6 3.9 1 23 476 498 476 498 0.96 9 12 0.00014 0.01 16.1 3.6 2 23 505 526 504 526 0.96 10 12 3.8e-05 0.0027 18.0 0.3 1 23 639 662 639 662 0.96 11 12 0.01 0.71 10.3 1.2 1 19 668 686 668 690 0.94 12 12 1.7e-06 0.00012 22.2 4.1 1 23 696 718 696 718 0.99
Sequence Information
- Coding Sequence
- ATGGAGGAGGGGGCCCAGTACTCGGTGCACGCTGTGTGCCGCATCTGTCTGAACCGCCTACCAGACGACGGCGCTGGAGCCGGATGCTTTGACCTCTTCCTGATCCCCGGCCTGGCCAAGAAGCTATGTGTGTGCACCTCGCTGGTTGTGGACCAGTCAGATGGCTTCCCCAAGAACCTGTGCACGCCCTGCTATGCCCGGCTGGACGATTTGCACGAGTTCCAGAAGCTGTGCGTAGACTCGGTAAAAAAGTTTCAGGATCTGGTGGCCAGGAACGTTTTCAGCGCTCCTTTGAGCGCCCAGATCAAAACCTTTGACGTGCTGAATGTGGCCGGAAATGGGGCTGAGATTGGTGGGCAAGAGGAAGAAGATCGCATCAACTTTGACCCGCTGCTGGATCACAAAATGGAGCTGATCGAGAACGAGGAAGATGTTTTCAAGATGCTGGAGCATGTGGACAAGGAGGCCGAGGAGGTCGAAAAGAAGGTCAAGCACGACGAAAACGAGGCTGAAGATTTAATGGCTTTCTTCGGTGGGGATTCCTCCtcggagagcgagagcgacaACGACCAAGATGTGGACTTTGAGCCCAACACCAGCGACGACGACCTGCCCCTGGCGCAGCGCATGAGAGTGAGTCCGAGTCAGGCCAAAGCCAAGGTCAAAAAAGCTTCCGTTAAGGTAGAGGAGACGGAATTACTCTCTGGCTCCGAAGAGGAGGATGACGAGGGAAGTAAAACGAAGTCCAGACGCCGGAGAGTACCGCCAGGCGAAAGACACCTGCACCGCATCATTGACTGCCACATCTGCCACCAGAAATTCAAGAAGGCCATTCGCTACGAGGAGCACATGAAGCACCACAACGACCTCCTGCCCTTCCAGTGCAAAGTGGAGACGTGCAGGAAAGGCTTCACCACCGCAGGCGGCCTGAGGCTTCACATCGACCATGCCCACACGGAACTGTCAGAGGTGCACAACTGTAGCTTTGAAGGCTGTGGCAAGTCCTTCCCGCGCATCCGCCTGCTCACCTTCCACATGAAGAAGGTACACGGGATCACGAAGGCGGCGGCGCCGCCGCGGGATTACCCCTGCTCTGAGTGCGAGAAGGTCTTTCGTTGCCCCATGGCCCTCAAAAAGCACATGTACAAGCACGACGGGAAGGAGTTGCCGTTCCCCTGCAATATTTGCGGCAAAAGGTTCGTGATCAACAGCGCCCTGAAGGATCATTTGATGCGGCATGCTGGCATCAAGAACTACGTCTGCCCATACTGCGGCGTGGGCAAGACCACGCGGCAGGAGTGGAACACGCACATCCTGACGCACACGCAGGAGAAGAAGTTCAAGTGCCACATTTGCGAGCACGCCTCGCACAACAAACAGAGCCTGGCCAACCACATCAAGATAGTTCACGAGAAAATCAAGAACTACGCGTGCCAGTACTGTGGGAAGACCTTCGGCAAGTCGCACGCCTGTAAGATCCACGAAATGACGCACACCGGGGAGAAGCGGTGCGAGTGCAAGGTCTGTGGCAAGAAGTTCCTCTATCCCAAGAGCTTGACCAAGCACCTAAAGACGCACGAGAAACGAGTGCTCAGGGCCATCGAGACCTATCGCCAGCGGCAGGTGGAGATGGGCGAGACAGCCAGCGATCAGCTGGGATCATCTCCTCTAGAGCTTCAGACGGGCATGCCAGTCGAGGGCTTAGTGACCAGCGAACCAGCCATCATGTCGCAGAATGCTGCTGACGAACTGCTTAAGGTCTGCGCCGAATCAGTGGCCACAATACCCAAAGATCCGCGCCGCGTGCAGCGCGTGGACATTGCAGAACTGGCTGGCACTGCTGTGAATCCCATACCATCAGTCTCGGTGCCATCGTGGTCGCCACAGGTGAACTTCACCAAAAAGGAGGGCAAGCACATCTGTCCGGGCTGCGGACAGGGCTTCAATAATATCGGAAACATGAAGCGACACTACAAGATCATCCACGAAAAGGTCAAGGACTTTGCCTGCCGCTTCTGCCCCAAGCGATTCGCCAAGGCCCAGACTTTGCGGCACCACGAATGGATCCATACGGGCGAGAAACCCTTTGAGTGCAAGACTTGCGGCACGCATTTCCGCCAGGAGACGGCTTTGAAACGACACCAGCGTACCCACGAGAACCGTCCGCCCGTTATCTCGCCCAAGTTCTATGCCGCTCGCGAGGAACTGGAAGAACAGGAGCGGAGCAAGCGAGAAGCAAAACGGCAGGCGGAGCTCAAGAAACGAGAAATTGCCGAGGCGGCCAAGGAGCAACTATCTTCGTTGCACAAGCTGGAGGGCGCCAGCGGCGATCATCGCCCCCTGCATTCCTACGACGAGTAccaggaggcggcggcggaacGCGCCGCTGCTTCAGCCGAACTCCAGGCCCAGCAGTTCGAGGAGAACGCGGTCAAGCAACGGGCGGATGAGGAGCGTCTAAAGATCCAGGAAGCTGCCTACGAGCAATTGCAACggcttcagcagcagcaggaactggACAAGGCGCAGACCTCCTACGATGGCTACTACGCGCAAAAGGTGAACGTGGACGGGACCACTCTGGACGCCTTGAAGATGGACCATGTGTGA
- Protein Sequence
- MEEGAQYSVHAVCRICLNRLPDDGAGAGCFDLFLIPGLAKKLCVCTSLVVDQSDGFPKNLCTPCYARLDDLHEFQKLCVDSVKKFQDLVARNVFSAPLSAQIKTFDVLNVAGNGAEIGGQEEEDRINFDPLLDHKMELIENEEDVFKMLEHVDKEAEEVEKKVKHDENEAEDLMAFFGGDSSSESESDNDQDVDFEPNTSDDDLPLAQRMRVSPSQAKAKVKKASVKVEETELLSGSEEEDDEGSKTKSRRRRVPPGERHLHRIIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVETCRKGFTTAGGLRLHIDHAHTELSEVHNCSFEGCGKSFPRIRLLTFHMKKVHGITKAAAPPRDYPCSECEKVFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQEKKFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHEKRVLRAIETYRQRQVEMGETASDQLGSSPLELQTGMPVEGLVTSEPAIMSQNAADELLKVCAESVATIPKDPRRVQRVDIAELAGTAVNPIPSVSVPSWSPQVNFTKKEGKHICPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPKRFAKAQTLRHHEWIHTGEKPFECKTCGTHFRQETALKRHQRTHENRPPVISPKFYAAREELEEQERSKREAKRQAELKKREIAEAAKEQLSSLHKLEGASGDHRPLHSYDEYQEAAAERAAASAELQAQQFEENAVKQRADEERLKIQEAAYEQLQRLQQQQELDKAQTSYDGYYAQKVNVDGTTLDALKMDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00504136;
- 90% Identity
- iTF_00531813;
- 80% Identity
- -