Basic Information

Insect: Drosophila borealis
Gene Symbol: -
Assembly: GCA_035045885.1
Location: JAWNOR010000040.1:419483-434136[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.013 1.1 10.2 0.8 1 23 716 738 716 738 0.95

2 7 1.8e-05 0.0015 19.2 1.1 1 23 744 766 744 766 0.98

3 7 3.1e-06 0.00025 21.6 0.2 1 23 772 794 772 794 0.98

4 7 1.7e-06 0.00014 22.5 1.2 1 23 800 822 800 822 0.98

5 7 0.0005 0.041 14.7 1.8 1 23 828 850 828 850 0.97

6 7 5.4e-06 0.00044 20.9 2.4 3 23 858 878 856 878 0.94

7 7 3.9e-05 0.0032 18.1 1.1 1 23 884 907 884 907 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.013	1.1	10.2	0.8	1	23	716	738	716	738	0.95
2	7	1.8e-05	0.0015	19.2	1.1	1	23	744	766	744	766	0.98
3	7	3.1e-06	0.00025	21.6	0.2	1	23	772	794	772	794	0.98
4	7	1.7e-06	0.00014	22.5	1.2	1	23	800	822	800	822	0.98
5	7	0.0005	0.041	14.7	1.8	1	23	828	850	828	850	0.97
6	7	5.4e-06	0.00044	20.9	2.4	3	23	858	878	856	878	0.94
7	7	3.9e-05	0.0032	18.1	1.1	1	23	884	907	884	907	0.98

Sequence Information

Coding Sequence: ATGGCGCTAGAAATAACAAACTCAATATTATCGCTGCAGCCAGCAATTGAGGCTGAAACGCTGGCGCCGCAGTCATTCCACTGGCAGCTCGAGGATTACGCATACTTTCACAAGTGCGGAGAGATAACCAGCTCGCCGGACGTACAATGCTTTGGCTTCAATTGTGCTTTCTGCCCGGCGATTTGCCTGCAGCTATCGGTTTTCATCGATCACATACGCGGCCAGCACATGCAGGACATGCGCCGGCGCTACGAGGGCGCCGATGACAAAATCGAACAAACAACGCAAACGGACTTTAACCTAATGATAAGGGACATGCAGCGGGACCAAGTGGAcacaacagcgacagcaacaactccAGCACTGACAGCTGCAATGGCCACAACAAATACGCGCCCGGACAAACGCACAAAGAATCCGAACTGGAATGAGACGCAGGGCCCGGGGCTCATGGATATGGGCTTGGACTTGGGCCTAGACCTGGCTGGCATGGTGCAGGCCCAGGCACTGCCAaagacaagcaacaacaatgcgactCTACTGCAGCTTGGCAACAAgaacccaacaacaacaacaacgacgacgtcgacaCCAGCCGACCTGGACTTCGTTTATGTTATGGAAAATCCAATGCCACCCTCGCCCCCACCGTCGGCTGACATTTCGAGTGACGGGAACAGTCCGTCGCGACTGCACTCGCTAGATCCGTTCGAAATGTTGCATGAGGCGGTCTCTTCTTCAGTCGAGCACACGGCCACGGCCACACCCACGCTGTTGTTCGAGGCGGTCTCCAGAGGCGGCGACAATGTTGTTGCACCGCCCCGTTATGAGACGCGGCGCGTGGCAATGCAGCGCAAGCTGCGCGACGCGGAAAAACAAACCGCAACAACCGCAGCGGAGGGGCAACAACTACAATTAGAGCAGCGCCAGCGTACGGAGGAGAACGCTGGAATGCTGGAGCTAACGCCGCCGGCCACGCCGCCAACACCAATGCCGCCCACCTCGCCGACGAGCAGCGTCGCGAGCAGCGTTGACTTGAAGCTGCGCACGCGTCGCGAGCTTGAACGCAATCGAGAATTCGTGTGCTCCCTGCTGGTGGCCTACGAGCGGAACGAGAAACTCTGGAATCCCAAGCACCCGGACTACAAGTACAATGCCAAGCGCAGCGTCTATGGTGAGCTGGCGGCGCCGCTTCAGGCCGTCTTCCAGATGCCACTGACCGGCGCCGAAATCTTTGCGGTGCTCAAGGAGCTGCGTGGACGCTATCGCCGCGAGCTCAGCAAGCTCAACTCCTTGGGCGAGAAATACAAGTCGCGTCTGTGGTACTTTGAGAAGATGCATTTCTTACGCGGCGTCATCGAGCACAAGCGGGCCGAACGGGAGGCAAAGAGCGAGTCAACGGAGAGTGAGAAATCAAGTGAAACGGACAGTGAATCGACTACAAAGTCGGCGCAGTATCGTGAGGTGCTCAGTTGCATAATAGATGCGTTTAGGCGCCAGGAGAGTCTGTGGAATCCGCAACACTTTGACTACAACAACTGCTGCAAGAAGGAACTGTACCGGGAGATCTCGGCGGAGCTGCTGGAGGAGCTCAACTATGAGATGACTGGCGAGGAGTGCTACAAGGAGTTGCAGAAACTGCGCACTCGCTATCGCAAGGAACTCCGCATGGTGATCAAGCACAAGGGTCTCTATCTGCCGAAGCTGTGGTGCTACGATGACCTGGAGTTCCTGCAAAAGATACTCCAGGATCAGATCTTCAATAAGATAAGCAAGAAAAAGGGCGTGGTGGAAACGAATCATCGCACCAAGTTTATTGACGCCAGCAGCATAAGTTTTGTCACGCAGGACGACCAGCTGCAGTTCGTGGAAATCTATCGCAACTATCCGGCATTGTGGGACGTGGATCATCCGGACTTTCGCTCAAATGCCTATCGCAGTCAGGCCTTGGCCCAAATGCTGGACGAGCTCAACACAACTTTTCAGTGCACATACAGTTCGGCGGAGCTGGAGAAGACGCTGTTCGAGCTGCGGAAGGATTTCTCAGCGCAGAAACGGAAAATCCTTACCAATGTCTCGGGTTCCAGCAGTGTGCCGCTGCTGCATGCCAAACTTGGTCAGTTTCTCGAACCGAATCTGGGCCCCTTTCGCTGTGATGTCTGCGGAGAGCTGGTCAAGACCTGCGACCAGTACAAGGTACATCGCGCCGGCCATGACGGCACTCAGCCCTTTATTTGCACGCTCTGCGGCAAGGGCTTCCAAATGCCGTGCAATCTGACCGTGCATATACGCCGCCACAGACACGACTTTCCGTACGCGTGCGAGCAGTGCGATAAGCGCTTTGCCACCTCCACCGAGGTGGCCATACATATGCGCACCCATACCGGCGAGCGACCCTACATATGTGATCTGTGCGGCAAGTCCTTCAAGACGTGGTCGTTCTTCGACATTCATCGGCGCACGCACCTCAATCAGTCGTCCTTCCATTGCCCCATCTGCGACAAGGGCTTCTATGAGAAGAACCGCTTCACCGACCACATGAACGCCCATCTGAACATTCGCAAGCATTTGTGCACCGTCTGCGGAAAGACCTTTACCACATACGGCAACCTCAAGAAGCACACCGAACTGCATCTGGCCGTGAAGAAGTACAAGTGTACAGCTTGTGGCAAGCGTTTCGCCCAGTTCGCCAGCCTGCGCTGGCACAAAAAGCGTGAGCACACctcacaacagcagcagctgcagctggaagAGGTCGAGCTGGAGGTGGAAGCCGATGAGCAGCTATAG
Protein Sequence: MALEITNSILSLQPAIEAETLAPQSFHWQLEDYAYFHKCGEITSSPDVQCFGFNCAFCPAICLQLSVFIDHIRGQHMQDMRRRYEGADDKIEQTTQTDFNLMIRDMQRDQVDTTATATTPALTAAMATTNTRPDKRTKNPNWNETQGPGLMDMGLDLGLDLAGMVQAQALPKTSNNNATLLQLGNKNPTTTTTTTSTPADLDFVYVMENPMPPSPPPSADISSDGNSPSRLHSLDPFEMLHEAVSSSVEHTATATPTLLFEAVSRGGDNVVAPPRYETRRVAMQRKLRDAEKQTATTAAEGQQLQLEQRQRTEENAGMLELTPPATPPTPMPPTSPTSSVASSVDLKLRTRRELERNREFVCSLLVAYERNEKLWNPKHPDYKYNAKRSVYGELAAPLQAVFQMPLTGAEIFAVLKELRGRYRRELSKLNSLGEKYKSRLWYFEKMHFLRGVIEHKRAEREAKSESTESEKSSETDSESTTKSAQYREVLSCIIDAFRRQESLWNPQHFDYNNCCKKELYREISAELLEELNYEMTGEECYKELQKLRTRYRKELRMVIKHKGLYLPKLWCYDDLEFLQKILQDQIFNKISKKKGVVETNHRTKFIDASSISFVTQDDQLQFVEIYRNYPALWDVDHPDFRSNAYRSQALAQMLDELNTTFQCTYSSAELEKTLFELRKDFSAQKRKILTNVSGSSSVPLLHAKLGQFLEPNLGPFRCDVCGELVKTCDQYKVHRAGHDGTQPFICTLCGKGFQMPCNLTVHIRRHRHDFPYACEQCDKRFATSTEVAIHMRTHTGERPYICDLCGKSFKTWSFFDIHRRTHLNQSSFHCPICDKGFYEKNRFTDHMNAHLNIRKHLCTVCGKTFTTYGNLKKHTELHLAVKKYKCTACGKRFAQFASLRWHKKREHTSQQQQLQLEEVELEVEADEQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00559672;
90% Identity: iTF_00617100; iTF_00563379;
80% Identity: -