Basic Information

Insect: Drosophila borealis
Gene Symbol: L
Assembly: GCA_035045885.1
Location: JAWNOR010000206.1:2780988-2791320[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00089 19.9 2.9 1 23 166 188 166 188 0.98

2 17 0.38 31 5.6 6.2 1 23 194 216 194 216 0.97

3 17 1.8e-07 1.5e-05 25.5 3.2 1 23 222 244 222 244 0.99

4 17 1.3e-05 0.0011 19.6 0.4 1 23 250 272 250 272 0.99

5 17 0.013 1 10.2 0.1 2 23 345 369 344 369 0.92

6 17 0.00085 0.069 13.9 0.2 2 23 397 419 396 419 0.95

7 17 0.03 2.4 9.1 0.7 1 23 490 512 490 512 0.97

8 17 0.0083 0.67 10.8 0.1 2 23 520 541 519 541 0.91

9 17 0.0007 0.057 14.2 0.1 1 23 549 573 549 573 0.94

10 17 7.3 5.9e+02 1.6 1.6 2 23 609 631 608 631 0.94

11 17 0.0027 0.22 12.3 1.1 1 23 688 711 688 711 0.97

12 17 0.0069 0.56 11.1 1.6 2 23 884 906 883 906 0.96

13 17 0.12 10 7.1 0.1 1 23 912 934 912 934 0.92

14 17 0.59 48 5.0 0.4 2 23 942 963 941 963 0.93

15 17 0.8 65 4.6 0.5 2 23 1064 1085 1064 1085 0.94

16 17 0.034 2.8 8.9 0.0 1 23 1095 1117 1095 1117 0.96

17 17 0.00024 0.019 15.7 1.2 1 23 1122 1144 1122 1144 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00089	19.9	2.9	1	23	166	188	166	188	0.98
2	17	0.38	31	5.6	6.2	1	23	194	216	194	216	0.97
3	17	1.8e-07	1.5e-05	25.5	3.2	1	23	222	244	222	244	0.99
4	17	1.3e-05	0.0011	19.6	0.4	1	23	250	272	250	272	0.99
5	17	0.013	1	10.2	0.1	2	23	345	369	344	369	0.92
6	17	0.00085	0.069	13.9	0.2	2	23	397	419	396	419	0.95
7	17	0.03	2.4	9.1	0.7	1	23	490	512	490	512	0.97
8	17	0.0083	0.67	10.8	0.1	2	23	520	541	519	541	0.91
9	17	0.0007	0.057	14.2	0.1	1	23	549	573	549	573	0.94
10	17	7.3	5.9e+02	1.6	1.6	2	23	609	631	608	631	0.94
11	17	0.0027	0.22	12.3	1.1	1	23	688	711	688	711	0.97
12	17	0.0069	0.56	11.1	1.6	2	23	884	906	883	906	0.96
13	17	0.12	10	7.1	0.1	1	23	912	934	912	934	0.92
14	17	0.59	48	5.0	0.4	2	23	942	963	941	963	0.93
15	17	0.8	65	4.6	0.5	2	23	1064	1085	1064	1085	0.94
16	17	0.034	2.8	8.9	0.0	1	23	1095	1117	1095	1117	0.96
17	17	0.00024	0.019	15.7	1.2	1	23	1122	1144	1122	1144	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatTCAAGCCACCAAGGAGATTACAAATAACGACATGTACAGCACGCACACCTCCTCCAGCTACTCGCCGAGCATCTCGGATGGCACATTGACGCCCAATtcgcagcagcatcagccaCAATTGGCGACAGCTGCCGCGGCGCACACATTGGAGCCCAGAGGCGAGGAGTCTAAGGCGAATGGTGAAGCTGTTGCCGCACAGTcggagctggagcaggagcaggaggcAGGCAGACCCAAGCGACCTGCCCAtttgcatcatcatcatcatcatcattatcatcatcagcagGCGCTGAAAATTGCGAACAAGCTGCGTAAAATCAATAAGGATGCCAAACTGGCAGCTAGTGGCACAGGACCAGGACACGGAACAGCCGCCAAGTTTGATAAGTTGACAGGCGAGGGCATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTGCAGaGTCATGCTGAGCATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTCTTCAAGCACAAACGCTCCCGAGATCGTCATAAGAAGCTCCATACCAACGAGAGGAACTACAAGTGTCCGCATTGTGAGGCTGCTTTCTCAAGAAGCGATCATTTGAAGATTCACATGAAGACGCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCCGCTTTGACCTCGCACATGCAGAAGCATAAGAAGAATGCCGCCATCCTGGCAGCTGGCGGCAATCCCAATGCTCTGAACTATAGCCCCAGATCGACGGGCTCCGCTTCCATATCGAGCAATGGCAGCCTGCACAAGCGTCGCTATGCGCTGGCCCTCGCCTCCGACAGCAGTCCCAGTCGCATGGATTTTCCCAAACGGGCGCGGGCTCATGTCccgaccacgcccacaccgACACCGCTGCTGCGCTGCAGCTACTGTCCCAAGGTGACGGAGTTCAGCAGCCTGGAGCAGCTAAATGCGCATCTGCAGAGCGCACACGAGCAGCGAGAGACGCGCAGCTCGACCGCCACGGCTGGCGGGGACGTTGTGGAGGCTGTGCAGGCGAACGGCTTCCAGCTGAGCTGCGAATACTGCACCATGAAATTTGTGAATATTGCCGCACTCTTCCAGCACATGCGGGCCACACACCTGGATCGGCTGAGCAGCCCGAACTCCTATTACGAGCACTTCAATCGCCTGGCCACGGCGGGCACATTTAGTCCCAGGCTGGCGCTGGAGCTGCCCAAAATCAAGCAGGACCTGGCCAGTCCACAGGCGCCGCCTGCCGAGAAGCCGGAGCAGGAGCTGCCCACAGACCTGAGCAGCAATAAGCGACGCCCCATGACGCCACCGGGCGTCTTCTTTTGCAATCAGTGCAATGCCGGCTTGCCGGACTTTGAGAGTTTCCGGAATCATCTGAAGACGCACATAGCCGAGGGCATGCAGCTGATCTGTCCACACTGCGGCCTGAGTCTGCCCGAGCAGAGCGAATACGAACGCCACGTGGTTGCCCACTTTTTGATCAGCAGCTCCGAGTTCAATTGCAGCGCCAGCTGCGGCAAATCCTATGCCAAGGccgaggagctgcagcagcatttgcTCAGCGAACACGTGCTCACGATGCTCAAGTGCGCCCTCTGCTCGGAGCTGTGCGAGAATCGGATGTCCATGCAGCTGCATCTGGCCTGTGCGCACAGCCAGGAGTCGAAGCTGTTGCGCTGCAGCGCCTGCCTGGAGCTCTTTCGCAGCGACACGGACTTCCATGTGCATGTCAAGACGCGCCACCAGCTCGATCGTGGATCGGCAAATGGTGGATCagtcgccgctgccgctgccgccgctgctgcggctgctgcctcCGCGCCCGCCAATCCGCTGCAGTGCATGTTCTGTCGCGCTGTTTGCGCCTCGGAGCTGGAAATGCATTTCCATTTGGCCGCGCATGCGCGTCAATTCCGTTGCCCCAGCTGCCCGGAAACGTTCCATGTGGAATTTCTGCTCGATCGCCATATGCAGAGCCAGCATGGCGGCGGCGTTAAGGATAAGGAGCCCGGCTCCAATGGGGCAATGGGCAGCCTCTATGTGAATGCCCTGCTGCCTCccctggcagctgctgccgctgccgccgccgcggcgaccaaccacaacaacaacaacaacagcaacctgCACATCGACTACAATGTGGCCTTCAAGGGCCTGTTTGGCGGCACGCCGAGCCCAGCGCAGTCGAACCACAAATTCTATAGTCCACTGCAGGTGGACACGAGCGCGCTGAAGCCACAGCAAACGCCGCATCCGGCTCTGATGTACGGCCTGAGCCAGCGCTATCTGATGGAAATGTATGCGGCCAAGGCCACATCGCCGGCGGCCAGTGCACCCGAGCTGCCGGCTGCCAGCAGCCAGGCCACGGCTACAGCGTCCAGCGCTGggagcagcagctacagctgcGGCATGTGCGAGCGGCAGGATTTGCGCAGCGAGGCGGAACTGCATTCGCATCGCAAGCTGGCGCACAATTTGAAGACAGGCGTTAGCCTGAGATGCGCCTATTGCTCCGGCAATTACAAGTCGCGCGCCGAGCTGGAGCAGCACATGAAGAGCTGTCACAATTCGAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTTCCCTCGCCCGCCATACTCGCCGAGCACAAGCTGCAGCACAGCAAGGTCGGCCAGTCCGGCAAGTGCGCCCACTGtggccagcagctggagcatGTGGCCGCCTTTCGTGCACATCTCGGCGAGCATGGCAATGACGGGCACCTGCCCATGGCCTGCATCTGTTGCCGCCAGACATTGCACTCGGAATTCGAGCTCAGCTTGCATGCCAAATTCCACACCAAATCGCCGGGCAGCGGCAGTCTACAGGAGCCGGTCTGTGCTCTGTGCCTGGAACCGTTGCCGGGCGCAGCGGGTGAAACGGCCAAGCTGTGCGACAAATGCTGTCGCAAGCATAATCTCAATGGCAAGCGCAAGGAGTCAACGGCCGcggctcctcctcctcctcctgcccCCCCTGCTTCGGCAAACACTGGCTATCTGGAGAATCGCTGTAATCTGTGCAAAATGATTTTGCCGCACGCCCAAAAACTGCAGGAGCATCTCGTCGAGCACACCTTCGCCGGCACCGAGCAGCGCGGCTTCAATTGCTACATCTGCTCCGCGGTCTTCACGGCGCCCGCTGGCCTCTTGACCCACATAGCCGAGCATGGCGCGCGTCCCTATGACTGCAATCTGTGCCCGGAGAAGTTTTACTTTCGCGCCGAGCTCGAGCATCATCAGCGCGCTCATGAGCTGCGACCGCCACCtccagccgcagcagcagcagcagcgcgtgGAGCACAGCCCAAACAGGAGACGCACAGCTCCACGGCCAGCTCACCCCTGGCGCCCAGTCCCAGTCACATCAAGCAGGAGCTGTACGAATCGGAAACGGCCAACTCGCCCAATGCTGAGCAGCCCATtcaggaggaggaggaataTATCGAGGTGGAGCAAGTGCAGCAGGAGACGCTGCGCTCCGGCGAGCTGCTCAGCACCGAGcgctccagcagcagcgcctgA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQQHQPQLATAAAAHTLEPRGEESKANGEAVAAQSELEQEQEAGRPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAASGTGPGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRMDFPKRARAHVPTTPTPTPLLRCSYCPKVTEFSSLEQLNAHLQSAHEQRETRSSTATAGGDVVEAVQANGFQLSCEYCTMKFVNIAALFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKQDLASPQAPPAEKPEQELPTDLSSNKRRPMTPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEYERHVVAHFLISSSEFNCSASCGKSYAKAEELQQHLLSEHVLTMLKCALCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRSDTDFHVHVKTRHQLDRGSANGGSVAAAAAAAAAAAASAPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVKDKEPGSNGAMGSLYVNALLPPLAAAAAAAAAATNHNNNNNSNLHIDYNVAFKGLFGGTPSPAQSNHKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAASSQATATASSAGSSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGHLPMACICCRQTLHSEFELSLHAKFHTKSPGSGSLQEPVCALCLEPLPGAAGETAKLCDKCCRKHNLNGKRKESTAAAPPPPPAPPASANTGYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPPPPAAAAAAARGAQPKQETHSSTASSPLAPSPSHIKQELYESETANSPNAEQPIQEEEEYIEVEQVQQETLRSGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00531138;
80% Identity: -