Dbor008162.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila borealis
Gene Symbol
su(Hw)
Assembly
GCA_035045885.1
Location
JAWNOR010000194.1:645650-648975[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00067 0.054 14.3 2.2 1 20 219 238 219 240 0.94
2 12 2.8e-06 0.00023 21.8 0.4 3 23 291 312 289 312 0.93
3 12 0.1 8.2 7.4 0.1 1 23 318 340 318 340 0.96
4 12 7.5e-07 6.1e-05 23.6 2.5 1 21 347 367 347 368 0.95
5 12 3.3e-06 0.00026 21.6 0.6 2 23 380 401 379 401 0.96
6 12 0.0001 0.0085 16.8 5.3 1 23 412 434 412 434 0.99
7 12 8.1e-05 0.0066 17.2 0.9 1 23 440 462 440 462 0.97
8 12 1.6e-05 0.0013 19.4 0.8 1 23 468 490 468 490 0.99
9 12 1.5e-06 0.00012 22.6 3.0 1 23 496 518 496 518 0.98
10 12 0.0043 0.35 11.7 0.9 1 23 522 544 522 544 0.96
11 12 0.0001 0.0084 16.8 0.2 1 20 552 571 552 576 0.92
12 12 3.6e-05 0.0029 18.3 0.3 3 23 596 617 594 617 0.96

Sequence Information

Coding Sequence
ATGAGCGCCAGCAAGGTCGCCCAAGCGGCAACTCCCGCCTCCAGCAGCATCAACATTTCTGACGGAGAGAAACCCAAGGAAAAACGCACTGGCACACGCATGAAGCTGCTCAACGATGTGGCAGCAAAGGCTGCAGCTGCCAGTAAGGGCGCCTCCGTGTCGCCGCGCCTCAAGCCGGAGAAACGCACAAGCATCAACAtactcaacaacaacaacaacgatgaAGCTCAGAGTAGTACAAAGGGCGGTGATAGGCGTGCCACGCCCGAAACCGCCAGCACCAGCGTCAAGATATTAAACGAGAAGCGCTCTGCGCCCGCCAGCACAGCTGTGGAAACGGCCAAGATAAAGACATCGcccagcaagaagaagaaaatggATCACTATGTGCTGCAGGCCATCAAAAGTGAGAACAACAAAGCGGAGAACACGACCAGCGTGGTGGTGGTCGAGGACGAAGACACCATAGACTTTATACTGGCCGATGATGATGTCGAGCTCGGTGCCGGAGCAAAGGAGAATGGCGAAGAATTTGTGGTATCTGGCGTGGATGaagatgatgacgacgacgacgatgatgacgagGATGACGGTGTGGTGGAAGGCGGTGCTAAGCGCAGAAGTGGCAACAACGAACTCAAGGAAATGGTCGAGCACGTGTGCGGCAAGTGCTACAAGACATTCCGACGCGTCAAAAGCTTAAAGAAACACTTGGAGTTCTGTCGCTACGACAGCGGCTATCATCTGCGCAAGGCGGACATGCTCAAGAATCTGGAGAAGATCGAGAAGGACGCAGTGGTCATGGAAAAGAAGGACATATGCTTCTGCTGCAGCGAGAGCTACGACACCTTTCATCTGGGCCACATCAACTGCCCCGATTGCCCGAAGTCGTTCAAGACACAGACCAGCTATGAGCGTCACATTTTCATAACACACTCGGAGTTCAATGATTATCCCTGCTCCATTTGCAATGCCAAGCTGAGGAGCGGCGCGCTGCTAAAGCTGCACGAGCAGCAACATCAATTGCGCGGCAAGCCGTTTGCCTGCAAAATCTGTGGCAAGGACTTTACGCGCTCGTATCACTTGAAGCGCCATCAGAAATACTCGTCCTGCTCGGCCAATGAGAACGACACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTACCGTCTGGACAATTTGCGCGCTCATCTCAAACAGCATCTGGGCACCCAGGTGGTCAAGAAGCCGGAGTACATGTGTCATGTGTGCAAGAATTGCTTCTACAGCCTCTCCACACTCAACATTCACATACGCACCCACACGGGCGAGAAGCCCTTTGATTGTGATCTGTGCGACAAAAAGTTTTCGGCTCTGGTGGCGCTCAAGAAGCATCGGCGTTATCATACGGGCGAGAAACCCTACACCTGCACTGTGTGTAGCCAATCTTTTGCCGTCAAGGAGGTGCTTAATCGCCACATGAAGCGGCACACTGGCGAGCGTCCCCACAAGTGCAACGAGTGTGGCAAGAGCTTTATCCAGGCCACACAGCTGCGCACCCATTCCAAGACGCATCTGCGTCCCTACGCGTGCTCCATGTGTATCCAAAAATTCAAGACGGAGAAGCAACTCGAGCGCCACGTTAAGGATCATACGCGTCAGAAACGCGCCTCCTTTGCCTGCACGGAGTGCACAAGAAGTTTCCGCACCAGCGCGCTGCTCAAGGAGCATCTGGACGCTGGCGATCATTCGCCTGTTAAATCGACACGAGCCAAGCGCTCGGCCAAAATGATCGAGCGCACGGACTGCGCCATTTGCGATAAGAACTTCGACACTACCGAGACACTACGGAATCATATACGCAGCGTGCACGAGTGCGACCCGGATGACATCTTTGGCACGGAGCCACCAGCCAAGCGCAGAGCTAAGAAGACCGTCGTGGCaccggtggcggcggcggagcAGAAAGAGCAGGAGGAAGACTTGCCCGCTGCCAACACGTCAGCCGGCTCGCTCATCTCCAGCAAAACGGATGGCAACGGAGTCGTGGTGCGCGAGTTTCTGGTGGATGAGGGTGACGGCAACGCGCAGACGATTGTCCTGGAAAACGAGGTCTATACCATTTTGCCACTGGAGGGTGACAAGGCAACCGAGCCCACGGCCGAGACCGACGTCAAGGCCGAGTCGTCTAAGGAGAAGTCCTCTGTGTCGCCGGTGGTCAAGAAGGAGCAGCGAAAATCACTGGCCGCCAGTTTGGCCGCTGCCATTGCGGATAATCTGGAGGAGCCGTCAAGCGATGATGAGTTCGGTGGCGAGGTGCTAACCGAGGAGGATCTGAAGCTCAAGGAGAACATTGCCAAGCTAATAGACATGCTGGTCGATCCGCAAACCCTCAAGAAATATGGCTGGCCCAACAGCTCCGAGGAGTCGGTGCTGTGCAAGGTCATTGAGAACTGCGGCCACGATCTGGCCAAGGGCAGCGAAGCCTATGCCGAGTTGGACTACGGCAGTCGCATGCGCGAATATTGCAAGCTGCTTTTCACCGTGGTGATTCACAATGATTCGATAAAGGCGCTGCTCAACAATTTTCCCATCGACGATGTTATTGAGTATGTGCTGGGCGATGAGGATCAGGACCAGGATCAAGAGGCAGACAAGGGCAAAGACAAGGAGTCCGAGAACGAGGACACGGACACCAGAGATGATGCTGTTGAGTCGGAGGCTTAA
Protein Sequence
MSASKVAQAATPASSSINISDGEKPKEKRTGTRMKLLNDVAAKAAAASKGASVSPRLKPEKRTSINILNNNNNDEAQSSTKGGDRRATPETASTSVKILNEKRSAPASTAVETAKIKTSPSKKKKMDHYVLQAIKSENNKAENTTSVVVVEDEDTIDFILADDDVELGAGAKENGEEFVVSGVDEDDDDDDDDDEDDGVVEGGAKRRSGNNELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSGALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYACSMCIQKFKTEKQLERHVKDHTRQKRASFACTECTRSFRTSALLKEHLDAGDHSPVKSTRAKRSAKMIERTDCAICDKNFDTTETLRNHIRSVHECDPDDIFGTEPPAKRRAKKTVVAPVAAAEQKEQEEDLPAANTSAGSLISSKTDGNGVVVREFLVDEGDGNAQTIVLENEVYTILPLEGDKATEPTAETDVKAESSKEKSSVSPVVKKEQRKSLAASLAAAIADNLEEPSSDDEFGGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYGWPNSSEESVLCKVIENCGHDLAKGSEAYAELDYGSRMREYCKLLFTVVIHNDSIKALLNNFPIDDVIEYVLGDEDQDQDQEADKGKDKESENEDTDTRDDAVESEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00495995;
90% Identity
iTF_00506253;
80% Identity
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