Basic Information

Insect: Drosophila borealis
Gene Symbol: -
Assembly: GCA_035045885.1
Location: JAWNOR010000113.1:10168075-10172698[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0048 0.39 11.6 1.7 1 23 224 246 224 246 0.95

2 25 0.033 2.7 8.9 1.9 1 23 252 274 252 274 0.97

3 25 0.0071 0.58 11.0 1.6 1 23 404 427 404 427 0.92

4 25 0.32 26 5.8 0.6 2 22 438 458 437 458 0.96

5 25 0.34 28 5.7 0.6 1 20 467 486 467 488 0.93

6 25 0.12 9.6 7.2 0.4 1 23 500 522 500 522 0.98

7 25 0.0015 0.12 13.2 0.9 1 23 602 625 602 625 0.94

8 25 0.016 1.3 9.9 0.1 1 22 634 655 634 655 0.93

9 25 3.6 3e+02 2.5 8.6 1 23 664 687 664 687 0.96

10 25 0.00058 0.047 14.5 0.2 2 23 715 736 714 736 0.97

11 25 2.3e-06 0.00019 22.0 3.3 1 23 744 766 744 766 0.99

12 25 0.058 4.7 8.2 1.7 1 23 914 937 914 937 0.95

13 25 0.0066 0.53 11.2 1.0 2 22 945 965 945 965 0.96

14 25 0.15 12 6.9 0.5 1 23 974 997 974 997 0.91

15 25 3e-05 0.0024 18.5 1.9 1 23 1022 1044 1022 1044 0.97

16 25 0.00015 0.012 16.4 0.9 1 23 1051 1073 1051 1073 0.98

17 25 0.011 0.88 10.5 0.0 2 21 1100 1119 1099 1120 0.94

18 25 0.042 3.4 8.6 4.0 1 23 1165 1188 1165 1188 0.96

19 25 1.3 1.1e+02 3.9 0.5 1 23 1225 1248 1225 1248 0.93

20 25 0.0036 0.29 12.0 1.2 1 23 1273 1296 1273 1296 0.97

21 25 1.4e-05 0.0012 19.5 0.1 2 23 1320 1341 1319 1341 0.95

22 25 4.9e-05 0.004 17.9 2.9 1 23 1347 1369 1347 1369 0.99

23 25 2.4e-06 0.00019 22.0 2.0 1 23 1375 1397 1375 1397 0.97

24 25 6.1e-08 5e-06 27.0 2.4 1 23 1403 1425 1403 1425 0.99

25 25 0.00073 0.059 14.2 0.3 1 21 1431 1451 1431 1455 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0048	0.39	11.6	1.7	1	23	224	246	224	246	0.95
2	25	0.033	2.7	8.9	1.9	1	23	252	274	252	274	0.97
3	25	0.0071	0.58	11.0	1.6	1	23	404	427	404	427	0.92
4	25	0.32	26	5.8	0.6	2	22	438	458	437	458	0.96
5	25	0.34	28	5.7	0.6	1	20	467	486	467	488	0.93
6	25	0.12	9.6	7.2	0.4	1	23	500	522	500	522	0.98
7	25	0.0015	0.12	13.2	0.9	1	23	602	625	602	625	0.94
8	25	0.016	1.3	9.9	0.1	1	22	634	655	634	655	0.93
9	25	3.6	3e+02	2.5	8.6	1	23	664	687	664	687	0.96
10	25	0.00058	0.047	14.5	0.2	2	23	715	736	714	736	0.97
11	25	2.3e-06	0.00019	22.0	3.3	1	23	744	766	744	766	0.99
12	25	0.058	4.7	8.2	1.7	1	23	914	937	914	937	0.95
13	25	0.0066	0.53	11.2	1.0	2	22	945	965	945	965	0.96
14	25	0.15	12	6.9	0.5	1	23	974	997	974	997	0.91
15	25	3e-05	0.0024	18.5	1.9	1	23	1022	1044	1022	1044	0.97
16	25	0.00015	0.012	16.4	0.9	1	23	1051	1073	1051	1073	0.98
17	25	0.011	0.88	10.5	0.0	2	21	1100	1119	1099	1120	0.94
18	25	0.042	3.4	8.6	4.0	1	23	1165	1188	1165	1188	0.96
19	25	1.3	1.1e+02	3.9	0.5	1	23	1225	1248	1225	1248	0.93
20	25	0.0036	0.29	12.0	1.2	1	23	1273	1296	1273	1296	0.97
21	25	1.4e-05	0.0012	19.5	0.1	2	23	1320	1341	1319	1341	0.95
22	25	4.9e-05	0.004	17.9	2.9	1	23	1347	1369	1347	1369	0.99
23	25	2.4e-06	0.00019	22.0	2.0	1	23	1375	1397	1375	1397	0.97
24	25	6.1e-08	5e-06	27.0	2.4	1	23	1403	1425	1403	1425	0.99
25	25	0.00073	0.059	14.2	0.3	1	21	1431	1451	1431	1455	0.91

Sequence Information

Coding Sequence: ATGTTGCCGACGGATATTTGTCGCACATGCGCGCTACAGGATGACAGCTTGCTCCCGCTAGCAACGCGCactaataaatatgcaaataaaagttttaGCGACATATTGCACGAATTGACGCAGAGTGATCCCTTGAAGGACCATACGGATGATGGCCTGCCGCAGTATTTGTGTGGGAAATGCCTGCACAAGCTTGAAGCTGCCTATGCTTTTGTGCTGCAGGCGCGGCAGGCGCAggggcaactgttgctgcagctgcgcaaAGGTTTGCATACGAAGTGCTTGGAGGAGATGCCCATAGACATCAGCATGCAGGACATTAAAACCGAAGCGGAAGTTCACCTAGATTCGGAGCCAACCAGTAAAACTAAAAGTGAGTCGCTACTGCAAGATGCGGGAGAGATTGAAGAACCAGAGATTGCTGCAGTGTGTGGTCCAGCCTTGAAATGGCAGCCCGAAAGCGATAGCGACAATACTCAGGCGGCTGTTGATGAGCAGGACAGGGACTTGAAGCCCAAGCAATTGCGGCGCAGCGTACGGAAAGCCAAACATGGTATAGTCAGCGAAAATGAAGCCTCTTTTGCTAAAATGAAAACCTTGACTGTCAAGCGTCGTCGCGGGCGTCCCACGCGTCTtcccaaaaaagaaaacatcaaCGAGGAGGGCCGACATGCGTGCGAGGTGTGCGGTAAGACATTTTCGTGGCACCGCGACATGCTTCGCCATGCCCGCATACACTTCGAGCAGGCGGCCTACGTGTGCGACAGCTGCGGCAAGAGTTTTTTGCGCAAGGACAAGTATATGTTTCATCTGCGCTCGCACGAGAAGCGCGCAGCCAAACGGCAGGCGTTGCAGCTGAGTAGTGAATGGCGCTTTGCAGAGCGCCTCTACAGCTCGAGCCGGCTCAAGCATGTGCTCTGCAAGCTGTGCGGCTTGAAGTGCCAGCGCATACAGGAGTTACGCGATCATTTGGCGTGCCATGACAGCATTGAAACGTTGTCTAAATTGAGCATGGAGAGTGATGTGGTCAAAGAGCAGTTTGCcaacgagcagcagcaattggaCTTGGTCCAGATCAAGCAGCAAGTGTGCGCTGACATTGCCAAGGGACGTGAGCTGCTGGACAACTATTGCGCTGTGGTAAATGCATATGGTTATGAGCTTAGCCTCAGCGACTCGGATGAGGAACTAGCTAGCTTGACGCCACCATACCGCTGTCTGCCGTGCAACACCACCTTCACGCGCAAATATCGCCTCATGCGCCACACTCTGGAGGAGCACACGCATTCGGAAGCAGATGTACCCTGGCAACGTTGTAATGTTTGTCAAATTGGTTTTGTGTGCGCCAAGCTTCTGGAGCAGCATCAACGCACGCAATGCGACAATAAACTTAAACGTTATAGCTGCCCTAACTGTCCAGGAAAATTCATTTGGAAGCAGAATTTGAAGCAGCATGCGTGCTCCCAGCGCAAAGGGGTGCAAAAGGCCGCTCTTCAATTCCAATGTTGTCTCTGCGATGCCCAATTAATCAGCATGGGAGGATTACGCTCCCATTTACTCACCCATCGCGATGGATGCAGCGGCATAGATCCGGAGAAGCGGGCTGCCTTTTTTCGCACCTACTACCCCGATGGGTTGACCTGCAGCTTGTCAGAGTTGACCGCACGCATTGCCGGCGACTTTGAGGCAGAGGATTATGGACGCTATTTCAATGCCAGCACTAGCAGTGGGCAGGAGCTGGATTTTTTTGACTCGGAGACAGATTTGAGTGATGAAGAGCAGTTGAGCTCTGTCGCTGCGTTGCATATATGTTCACTGTGTGGCGAGACCACAATACGCCGGACCCAACTGCTTgcgcatcagcagcagcagcaccagcataGTGAGGCCAGGCTGCCGCATGCCTGCGAGGACTGCGACCTGAGCTTTGTAGCCGACTCCTTACTCCAACTGCATCGCCGACGTATCTGTGCCAAGCGGCATGCCAAGTATCATTGCCAGCATTGCAGCCAGCGTTTTTTCTGGCACTCCAACTATGAGCGGCATTTGAAGCTGCAGCACGAGACGGAGGATAAAACAGAGGTTATCCAAGAGCTGGAGCCCAGGTTAAGAAGCAAGCGCTATCCAACAGCAGCCAAGCTGCAGTGTGACGAGTGCGAAAAGGTCTTCATCTGGCCCAAGGATCTGACACGTCACAAGCGGCTGCATCAGCCACAGGCGCTGGCTCAGTACCAATGCGCCTACTGTGATCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCGCATATGCGCGTGCACGGCGAACAGCAGCTGGACGGAACGATTGCCAGTGATCAACCATCGTCCGTCCTGCAGCACATGCCGGTAGTGTTGGCCCAATTTTGCCGGCCCAATGGCTGCAAGCAGATTCAGTGCATGATTTGCCTTTCGCAGCACACAAAGATCGCCGATCTGCGCGCCCATTTACTCAACCATCAGTTTGCGGTGATGTTTGCAGCGGATCGTGGTAAGTCGGAGAGCATTGCAAGCATTTCACGTGCTCTATATCCAGAGCTGGCCACGCCGCTGGATCAGCAACAGCTGATCAGGCGCATTCAAAGCGATGTGGCCAAGGGTCTTGAACTGGAAAGATTCATATCCATTACCAACGAGGCGGGCATTGAGCTCAGCCTGGACAGCAGCGAGACTGAAACAGATTCTGACTCTGCCGAGGGAGTTGGAAACAGCAGCGGGCGTCTGTACAGCTGTGAGCTGTGCCAGCTAAAAGTACAGCGCAAGCATCAGCTCTACGCCCATCAGCTGGAGCAGCATACGTGGCAGCAGGCTACGCGTGTTTGCACCCATTGCCAGGCCAGATTTGTAAAtgagcagctgctggagcATCATTATCGCACGCTCTGCCGAAACGCGCAGCGGCGTTTTCTATGTCGCAAATGCCCATTGCGCTTTCGCTGGCGCGAGAATCTGAAGCTGCACACGGACGTAGCGCACCAGGAGGCAAGTGGAGAGCATTTGAACTTGAGCATTCAATTGAACGGCACACATCTGCTGCCTATTGTTAGCTATGACTGCACCGAATGCAGCCGCAgctttaaaatgcaaaaggaTCTCACCAGGCACACCCTGATGCATGCTCAGGAGTCGAGCATTTACCGTTGTCGCTGGTGTGCGCGGCGTTTCTATCGCCAGGCCAATCTTCTGCAGCATATCGAGCGTCACGGCATTAGCGCCGAGCAGCTGCCCTATGCGGAGGCGCTGCTCAATGCCAGCCGGCATCCGCATGGCCAGAAGTCCATCCAGTGCAAGGTGTGTAATATTTCCTACCCCACCATTGCCGCACTGCGCGCCCATCTCCAATCTGCGCCAGCAGGCTCACATCATCAGCTTGACTCGATGCTCAACTACTCTATAACCAATCAGCTGGGCTACGAGCTGCACCTGGACGACTCGGAAACAGATGAGGAGGCCAAGCCGCCGGGCACACCCCCACACTACACCTGCGGTATGTGCCAACTGCGCTGTGTGCGCAAGTTTGAActgcatcagcatcaacaggcCATGCATCGACTGGAACGCATAAGCGAGGGTTGCGAtctttgcatatttaaaagcGTCTCTCCTGATCTTATCAACTACCATCGTCGTGCGCTGTGCAACAACACAGAGAAAAAGTTCAAATGCATCAAGTGCGGCTACAAGTTTATGTGGGAGGCAAATCTGTTGCAGCACGTGAAGCTGCAGCACCCCAGTAGCGAGCTGCAGCAGGAAGTGACTTCAACGCTCGCAACGGAAACTTCCAGTAATGAGTGCCAGATCTTTCAGTGCGGTCAGTGTCCTAGTAAATATAATCGCAAGGATCGTCTCACAGCACacgtaaaaaaaaatcattcaGCAGAAACTAGCTCCAAGACTGCCCCAACAAAGGCTTCTACAGGCGCCAAGCAGCAGAAAAGTTTTCTTTGCGCCTTTTGCGGCAAGGCGGTTAGTTCCTCATCCAATCTGATCATACACATACGTCGGCATACTGGCGAGAAGCCTTTCAAGTGCGACTACTGCGACATGGCGTTTCCACGGTCCTCCGATCTGCAGTGCCATCGACGTACCCACACGGGCGAGCGGCCGCATGTCTGCACCGTTTGTCAGAAGGGCTTCGCGCGCTCCtacaagctgcagcagcacatGCGCATCCACAATGGCGAACGCCCCTACAAGTGTACTTATTGTGATAAGAGTTTCACCCAGTCGAATGATCTGACGCTGCATATACGGCGGCACACGGGCGAGCGTCCTTATCAGTGCAACACGTGCGGTGAGCGTTTCATTCAGGGTACGGCCCTCAAGAATCATCGACTACAAAATGGACACTACGAGGCGAAAGCAGACCAAGTAAAAGATGTCTAA
Protein Sequence: MLPTDICRTCALQDDSLLPLATRTNKYANKSFSDILHELTQSDPLKDHTDDGLPQYLCGKCLHKLEAAYAFVLQARQAQGQLLLQLRKGLHTKCLEEMPIDISMQDIKTEAEVHLDSEPTSKTKSESLLQDAGEIEEPEIAAVCGPALKWQPESDSDNTQAAVDEQDRDLKPKQLRRSVRKAKHGIVSENEASFAKMKTLTVKRRRGRPTRLPKKENINEEGRHACEVCGKTFSWHRDMLRHARIHFEQAAYVCDSCGKSFLRKDKYMFHLRSHEKRAAKRQALQLSSEWRFAERLYSSSRLKHVLCKLCGLKCQRIQELRDHLACHDSIETLSKLSMESDVVKEQFANEQQQLDLVQIKQQVCADIAKGRELLDNYCAVVNAYGYELSLSDSDEELASLTPPYRCLPCNTTFTRKYRLMRHTLEEHTHSEADVPWQRCNVCQIGFVCAKLLEQHQRTQCDNKLKRYSCPNCPGKFIWKQNLKQHACSQRKGVQKAALQFQCCLCDAQLISMGGLRSHLLTHRDGCSGIDPEKRAAFFRTYYPDGLTCSLSELTARIAGDFEAEDYGRYFNASTSSGQELDFFDSETDLSDEEQLSSVAALHICSLCGETTIRRTQLLAHQQQQHQHSEARLPHACEDCDLSFVADSLLQLHRRRICAKRHAKYHCQHCSQRFFWHSNYERHLKLQHETEDKTEVIQELEPRLRSKRYPTAAKLQCDECEKVFIWPKDLTRHKRLHQPQALAQYQCAYCDRKFHRKDGLKSHMRVHGEQQLDGTIASDQPSSVLQHMPVVLAQFCRPNGCKQIQCMICLSQHTKIADLRAHLLNHQFAVMFAADRGKSESIASISRALYPELATPLDQQQLIRRIQSDVAKGLELERFISITNEAGIELSLDSSETETDSDSAEGVGNSSGRLYSCELCQLKVQRKHQLYAHQLEQHTWQQATRVCTHCQARFVNEQLLEHHYRTLCRNAQRRFLCRKCPLRFRWRENLKLHTDVAHQEASGEHLNLSIQLNGTHLLPIVSYDCTECSRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPHGQKSIQCKVCNISYPTIAALRAHLQSAPAGSHHQLDSMLNYSITNQLGYELHLDDSETDEEAKPPGTPPHYTCGMCQLRCVRKFELHQHQQAMHRLERISEGCDLCIFKSVSPDLINYHRRALCNNTEKKFKCIKCGYKFMWEANLLQHVKLQHPSSELQQEVTSTLATETSSNECQIFQCGQCPSKYNRKDRLTAHVKKNHSAETSSKTAPTKASTGAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNGHYEAKADQVKDV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00563306;
90% Identity: iTF_00551040;
80% Identity: -