Basic Information

Insect: Drosophila bocqueti
Gene Symbol: ZNF212
Assembly: GCA_018151655.1
Location: JAECXF010000057.1:8043670-8045709[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.89 68 4.2 2.1 1 20 130 149 130 150 0.92

2 10 0.00019 0.015 15.7 0.5 2 23 202 223 201 223 0.97

3 10 0.00021 0.016 15.6 0.9 1 23 249 270 249 270 0.98

4 10 0.00014 0.011 16.2 1.1 1 23 277 299 277 299 0.98

5 10 3.9e-05 0.0029 17.9 0.6 1 23 331 353 331 353 0.98

6 10 7.4e-08 5.6e-06 26.5 0.9 1 23 359 381 359 381 0.99

7 10 0.001 0.077 13.4 5.5 1 23 387 409 387 409 0.98

8 10 4.2e-06 0.00032 21.0 0.8 1 23 415 437 415 437 0.97

9 10 1.9e-05 0.0014 18.9 0.3 1 23 441 463 441 463 0.99

10 10 0.0028 0.21 12.1 0.1 3 23 491 512 490 512 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.89	68	4.2	2.1	1	20	130	149	130	150	0.92
2	10	0.00019	0.015	15.7	0.5	2	23	202	223	201	223	0.97
3	10	0.00021	0.016	15.6	0.9	1	23	249	270	249	270	0.98
4	10	0.00014	0.011	16.2	1.1	1	23	277	299	277	299	0.98
5	10	3.9e-05	0.0029	17.9	0.6	1	23	331	353	331	353	0.98
6	10	7.4e-08	5.6e-06	26.5	0.9	1	23	359	381	359	381	0.99
7	10	0.001	0.077	13.4	5.5	1	23	387	409	387	409	0.98
8	10	4.2e-06	0.00032	21.0	0.8	1	23	415	437	415	437	0.97
9	10	1.9e-05	0.0014	18.9	0.3	1	23	441	463	441	463	0.99
10	10	0.0028	0.21	12.1	0.1	3	23	491	512	490	512	0.98

Sequence Information

Coding Sequence: ATGTCAACGCACATCGAGACTGAGGAGATTTTGCCCCACGTCCATGTGGTGGACGACGGACTTTCGTCGTCGAACTGTGGAACAACCCAACCGCCCCTTTTATACTGTGAGAGCTGCGGCAACATCTACGAGGACAATGAGACTTACGCCCAGGACCACAGTCAGCAGTTCGGCTGCTGCGTCGGTGGGGCCAATGTCAAGGACGAGTTCCAGGTTGTAGAGGAGATCATTTCGGACGAGCAGATCGAGATTGCACCAAGTTCGGCCGAGGAGGACAATGAAGAGGAGATCCTCGAGGCTGATGTGCCGTTCTGGGAGGTAGTAGATGACCCTTCCTTCACCAATAAAGTAGAACAAACCGAGACTGAAGCCACCCAATCAGATCGTTACTTTTGCTATGACTGCCACAGCATTTTCGAAAACAGAAGCAGTGCGGAGGATCATGTTTGTCCGCAGGCAGAGTCCGGCGGTGGTGGCACCATTCAACATGCAGTCGAGACGACTGCTGCCGCCACAACTAAACCACCGACACGCCGTAAGATGCCCAGCGTGGCGGCAGCAAGGGCAGATTCAAAGGGTGGTGGTCCACAACCATCTGTCATTAGCTGTGAAATATGTAATACCGTTTTTAGCTCTGCCAAGTTTCTAAAGTTCCATATGCGCATTCACGAGAAGGTTGCCCCCAAGAGCATTCAAGACGCCCTTCCCGTGGGCGCCCACCAGCAGTACAGTAAGCTGGATCAGTTTTACTGCGAGATCTGCAACAAGAGCTTCGACGAAAACCTACTGACGGTGCACAAGCAAATGCACCAGGAGACCGCCAAAGAGTTCATGTGTAGCATTTGCAACCGGCAATTCTACAATTCAATAGACTACAACATGCACCTTAAGATTCACCAAAAGCCTCGCGGCGACTCGGCGGATGCCGCCAAAATGCCCGAGCATCGCAGCGGTGGTGGTGGTGGTGGTGGCAAGAAGGAGAAGCCAGGCTTCCCCTGCCAGTTCTGCGATCGTGTCTTCTCTCGCCCCTATGAGAAGGTCAAGCACGAACGGGTGCACACTGGCGAGAAGCCCTACTCCTGCGAGGTCTGCGGCAAGACCTTTCGCGTCTCGTACTCGCTAACTCTCCATTTACGCACGCATACGAACATTCGGCCATATGTCTGTACCGTCTGCAATAAGCGCTTTAAATCACACCAGGTGTACTCTCACCACCTGCGCATCCACAGCACCGAGCGGCAGTTTGCCTGCGACGTATGCTCAAAGTCCTTCCGCACCTCCGTTCAGCTGTACGCCCATAAGAACACCCACACCAAGCCGTACCAGTGCGTCGTATGCAACCGACCCTTCTCGTCCATGTACGCCGTGAGGATTCACATGCAAACACATGAGGAAGAGAAGAGTAAAAGAAATGGAAAAGGCGGCGTACAGCCTACCAATAAGAACCAAACTTTAGCTGGGAAATTCTGGTGCAGTTCCTGTGGAGCAGAGTATGCACGTATATATGCCCTGCGGCTGCATATGAAGACGGCGCACGGACTGACAGAGGAAGTCATACAGCAGCAGGAGGAGCAGGAGCATTCATCGTCAGCAGCCCTAGAAGATGTCCTCGCCGCCACCGATGTAGACTCTGAGACTGCGGTGTTAATAGCAGCCGCCGAGGCTGACGCTGCGTATATTAATGCTGTGGTAAACGCTGTTGATGTCGTGGGATCCGTGCCCACATACGAAGAGGTGGCCGTTGAATTCGATGTGGACAACTTTCACAGCGAGGAGATTATTACCGACTGGCTTAAATAG
Protein Sequence: MSTHIETEEILPHVHVVDDGLSSSNCGTTQPPLLYCESCGNIYEDNETYAQDHSQQFGCCVGGANVKDEFQVVEEIISDEQIEIAPSSAEEDNEEEILEADVPFWEVVDDPSFTNKVEQTETEATQSDRYFCYDCHSIFENRSSAEDHVCPQAESGGGGTIQHAVETTAAATTKPPTRRKMPSVAAARADSKGGGPQPSVISCEICNTVFSSAKFLKFHMRIHEKVAPKSIQDALPVGAHQQYSKLDQFYCEICNKSFDENLLTVHKQMHQETAKEFMCSICNRQFYNSIDYNMHLKIHQKPRGDSADAAKMPEHRSGGGGGGGKKEKPGFPCQFCDRVFSRPYEKVKHERVHTGEKPYSCEVCGKTFRVSYSLTLHLRTHTNIRPYVCTVCNKRFKSHQVYSHHLRIHSTERQFACDVCSKSFRTSVQLYAHKNTHTKPYQCVVCNRPFSSMYAVRIHMQTHEEEKSKRNGKGGVQPTNKNQTLAGKFWCSSCGAEYARIYALRLHMKTAHGLTEEVIQQQEEQEHSSSAALEDVLAATDVDSETAVLIAAAEADAAYINAVVNAVDVVGSVPTYEEVAVEFDVDNFHSEEIITDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00613632;
90% Identity: iTF_00492376;
80% Identity: -