Basic Information

Insect: Drosophila bocqueti
Gene Symbol: zfh1
Assembly: GCA_018151655.1
Location: JAECXF010000001.1:3794765-3799045[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.5e-05 0.0019 18.5 1.0 1 23 151 173 151 173 0.97

2 15 0.00077 0.058 13.8 1.2 3 23 181 201 179 201 0.94

3 15 0.00025 0.019 15.3 0.2 1 23 367 389 367 389 0.98

4 15 0.00018 0.014 15.8 0.8 1 23 395 417 395 417 0.98

5 15 1.3e-05 0.001 19.4 2.3 1 23 449 471 449 471 0.97

6 15 0.0094 0.71 10.4 1.2 1 23 506 528 506 528 0.93

7 15 0.01 0.76 10.3 1.3 1 23 534 557 534 557 0.97

8 15 0.024 1.9 9.1 0.4 3 19 566 582 565 583 0.95

9 15 0.00015 0.011 16.1 5.6 1 23 592 614 592 614 0.97

10 15 0.043 3.3 8.3 0.4 2 23 620 641 619 641 0.96

11 15 8.5e-06 0.00065 20.0 1.0 1 23 650 672 650 672 0.98

12 15 0.00096 0.073 13.5 0.1 3 23 680 700 678 700 0.97

13 15 5.2e-05 0.0039 17.5 0.5 1 23 706 728 706 729 0.95

14 15 0.034 2.6 8.6 0.3 1 23 739 761 739 761 0.97

15 15 0.0052 0.4 11.2 0.2 1 23 1307 1329 1307 1329 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.5e-05	0.0019	18.5	1.0	1	23	151	173	151	173	0.97
2	15	0.00077	0.058	13.8	1.2	3	23	181	201	179	201	0.94
3	15	0.00025	0.019	15.3	0.2	1	23	367	389	367	389	0.98
4	15	0.00018	0.014	15.8	0.8	1	23	395	417	395	417	0.98
5	15	1.3e-05	0.001	19.4	2.3	1	23	449	471	449	471	0.97
6	15	0.0094	0.71	10.4	1.2	1	23	506	528	506	528	0.93
7	15	0.01	0.76	10.3	1.3	1	23	534	557	534	557	0.97
8	15	0.024	1.9	9.1	0.4	3	19	566	582	565	583	0.95
9	15	0.00015	0.011	16.1	5.6	1	23	592	614	592	614	0.97
10	15	0.043	3.3	8.3	0.4	2	23	620	641	619	641	0.96
11	15	8.5e-06	0.00065	20.0	1.0	1	23	650	672	650	672	0.98
12	15	0.00096	0.073	13.5	0.1	3	23	680	700	678	700	0.97
13	15	5.2e-05	0.0039	17.5	0.5	1	23	706	728	706	729	0.95
14	15	0.034	2.6	8.6	0.3	1	23	739	761	739	761	0.97
15	15	0.0052	0.4	11.2	0.2	1	23	1307	1329	1307	1329	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCGGCATCCAGTGGATACAGCACCACCCCGCTGCAGGCGACTCTTCCGAGACGGACCTTCTCGAGCATGAAGACGCCGATGGCGATGGTATGGTGAGCGGCGGGGACGGCGACCCAGACGGGGATGCGGATGCTGACCTGGACCATATGGCTGCCGAGAACCTGATCTTTATGGCGCGCGACGGTCAGCTGGGAGAGATTATCGCCGCCAATGAGGGAACTGTCCTGGTCACCGCCGATGGCACGACGGTGGCTTATGCGGAATCCTTTGACGACGATGCCCAGGTGGTCACCGAGGAGGTCATCACCGACGATTGGGTGCAGGACCAGGGAGCCGAGCGCGTGGAAATCGCCGCTGAGCAGATAGCTGGCATCAGTAGTTCCCAGGAACTATTGGACATGGAGCAGGATGAGTACACGGCTTTGCGTCCCTATCCCTGCGACTTTTGCAGCCGGCGCTTTCGGAAGAAGGCCAGCCTGAACAACCACATGCTGGCCCACCAGAACGACCGACCTCATCTCTGCAAGCTGTGCGGAGCGCGCTTCTCACGCCGGGCGGAGCTCATTAGCCACTTCAAGGCCCACGCCGAGGCCCAGGATGCTGCTGATGCCGAGGCAGCCGCCGCCGCTGCCGTTTCGGCCTCTTCCATAAAATTCGAGCATCAGGGCCACAGGCAGATGGATGATCATTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAGGTCCAGTTTGTGGCCAGCTACACAGCAACGGTGGCTCCTCCGCCTGCTCCGTCGCGCGGAAGGATTAGCAGGCTGAAACCCAAGGAGGAAAGCAGCCAGTTCATCGTGATAACCGACAAGTCGACGTCCAGCGAGTTGCAGGACTACATGGTCAGTGAGCCGGTGCCTCAGCCTATGGTGCCGGCACCGCAGCCCATGGCCATTGATCCGCCGCCTGCACCAAAGCCAAACTTCCCGGTGCTAGACGACAGCAAGCCCTTCGTGTGTCAGCAATGCGGATTGGCTTTTGCACGGGAAAAGGCGCTAGTCTCGCACACAAAGAACCATCGCGTGGACTCTCCCTTCGAGTGCAACCAGTGCCAGGAGATGTTTTGGGACAACAGCACCCTGCAAGACCACCAAAAGACGCATCAGTTTGAGGAGAGCAACTCTGAGTATGATCCCGCCTCTGGCGATGATAGCGCCAGCGAAACGTCGGAGCCGGAGGAGCAGCTCTACGGGGAGTTCTACTGCAACGAATGCGGCATCTCCTTTCATCGTCAGGATCTACTGCGGCGTCATGCCAAGCAGCATTTCAAGCAGCAGCAGGATCATAATTCAACGGTGGCGGCAGGAGACGGAAGCTCATCGGACATCATAGCTAGCGGGGATCAGGCCAAAGATGGTAACGATGGCCACTGTTGTCAAACGTGCGGCAAATCATTTCCCAGTGCCTTGGAGATGCTTTCCCATGCCGAAATCCATGCGAGGTTTCCGCCTTTCAAGTGCGTCCTGTGCGGCATAAGTTTCTACGAGGAGCAGGCCATCAAGCGGCATCTGCACACTCGTCATCCCAACGAACTGAAGGCCAACTCCTGCGTGCTGTGCGGCAAGGAGTGTCGCGACCGCAAGGCCCTGATCAAGCACGCCTGGGATCACTCTCGCGAAAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTTCATAATAAAGCGCGACTGAAGCGGCACATGGCCTCGCATCGTGACAAGTCCGTGGTGTGCGAGGTCTGCCAGGAGGAGTTTCCCGACGGCCGCACGCTGTCCAATCACCGTCACTCGCACAGCACCACGTCGCCAGGAAAGCTATTCCCCTGCCACGAATGCGGCAAGACATTTGGGTCACGCAGCTCCCAGCAGATCCACGTGCGCATTCACACGGGTGAGCGACCCTACGGCTGCCGTTACTGCTGGAAGGCCTTCGCCGATGGAGGAACGCTGCGCAAGCACGAACGTATCCATACGGGCGAAAAGCCCTACGCCTGCTCTGTCTGTCCGCGGGCCTTCAATCAGCGCGTGGTGCTGCGCGAGCACATCCGTTCCCACCACTCCGGTCTGGATGCGGCGAGGAATACGTACCACTGCACGGTCTGCTCCGAGGATCTGGCCTCGTCCAATGACCTCATACAGCACCTCATCCAGCACAGTGATTCGAACACCGCAAAGCAGCGTCAACCAGTGACGGGACCGCGGAAATACAAACGTCGACGAAAGCTGCAGCCTCATGAGATTGCGAACATGCGAGCAGAACACAAGGATGCTAACGGCGGCGACGAGGAAGAGATCCTGGGAGGCGAAGGTGATGGCGATGGCGATAACGATGGAGAGGAGTATGCTAGCGACATCGACCTTTGCGACTTTGACGTGGAGAATGTGGACGATCTCTTTGAAATGGCCGAGTCTTCGCCCAAAAAGGAGAAGCGTAAGAGGACATCGGCAGCGGCATCGACGAAGGCAGAACCTAAAGCTGTTTCCAATGGCGGCGGATCGTCGGGGAAGCCTGTCCAGGAGAAAAACAAGGCCAAGCTGCGCTACGACTCTACCAGCAGCCAGCAATCGGATCGCATTTGGGAGGAGAAGTTTTTACAGGACAATCAGGTGGCGCTCTTCCAAATCGATTCGCTGGTGGTGGTCAACGATACTCACCTCCAACCCGCGAGCTCAGCAGCCATGCCCAAGACGAGAGGTGGCACCAGACAGCAGCAACTGCAGGCCAAACAGCCCACTGAAAGAGCTGCTGGAAACTCCAATCCCTCGGCTGCAAGCTCAGTTGCCACCTCATTAGCCTCCGCATCCGCATCCGCCACTACATCCACTTCCAGCAATCGTAGCAGGAAGAAGGCGGCCGCCGTAAAGACAGCTGCTGCCTCACGACCCCGCATGATTCACACGGAAAAGGCCAAGGTGCCGTCCAAGGGAAATGCCAGTGGAGAGTTGGCCAAGAAGACACGCTCCAAGACGTACATCACCCGCACGGAGACGACCAATCTGAGCAGCCTGGACAAGTCGCAGAGCAGAGCGTCCAACATCGTGGATGACTACGAAATCATTTCACCGGCTACCCATCCGCCCAACCAGATCAGCTCCAGTCCCCTGCACATCAAACAGGAGCAGGAGCAGCTGCACCGTGCCCAGATGATGTACGACGACAACCTCCTGATAGACGCCGCCCTGCTGCGGGAGAAGACCTACGAGAAGTTCAACCCGAGCATTGTGAACGATCTGGAGGAGATCCTGCGCTCGCCGCTCAAGCACGAACGCAATACCCGCCTGCGATTCACCAGCGAATCCTCGACCACGCCACAGTTTCTGCCCGAAGAAGAGCAGAATCTGATTAAGATCGAGCCCACGTCTCCGGACTTGCGGGAGATGCTGGAGAGCCAGAGTCAAAGGGTGAGAGTACCAAGTGGCAACACACCGTCGCCCTCGTCCTCCTCCGCCAGAACTTCCCGTCATCGTATGATCACTGCCAGTGGCCCAAGGGCAGGGAACAAGAGATCCGCAGGGGGTGGCGGAAGTGGTAGCAGCGCTAGCACATCCTCACCTGCCCCAGGAGTGCCGGCAAAGAAAGTAAGCACGGCAGCCAGTAAGGTCGGTACCTCGTCCTCGTACCTCAATTACGGAGTGGATGCCTACAACGTGAACGTACCTGCCAGCGCCAGCGCTGCCGATGTGGGCAGCGGATTCTTCTCCATCTCGGAGGTCGTGTCGGCCGCCGATGCAGCTGATGCGGCGGCCAAGGCGGCGGCGGCCGGGAAAACGGAGCGGAAAACGCGATGTTTCGAGTGCGAAATGTGCTCGGCCATCTTTTATGATCGAGCCCAGTTACTGGACCATGTGCACATCCACATCTAG
Protein Sequence: MNNQDYGGIQWIQHHPAAGDSSETDLLEHEDADGDGMVSGGDGDPDGDADADLDHMAAENLIFMARDGQLGEIIAANEGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQDQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAAAVSASSIKFEHQGHRQMDDHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEVQFVASYTATVAPPPAPSRGRISRLKPKEESSQFIVITDKSTSSELQDYMVSEPVPQPMVPAPQPMAIDPPPAPKPNFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSTLQDHQKTHQFEESNSEYDPASGDDSASETSEPEEQLYGEFYCNECGISFHRQDLLRRHAKQHFKQQQDHNSTVAAGDGSSSDIIASGDQAKDGNDGHCCQTCGKSFPSALEMLSHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIANMRAEHKDANGGDEEEILGGEGDGDGDNDGEEYASDIDLCDFDVENVDDLFEMAESSPKKEKRKRTSAAASTKAEPKAVSNGGGSSGKPVQEKNKAKLRYDSTSSQQSDRIWEEKFLQDNQVALFQIDSLVVVNDTHLQPASSAAMPKTRGGTRQQQLQAKQPTERAAGNSNPSAASSVATSLASASASATTSTSSNRSRKKAAAVKTAAASRPRMIHTEKAKVPSKGNASGELAKKTRSKTYITRTETTNLSSLDKSQSRASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQLHRAQMMYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHERNTRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMLESQSQRVRVPSGNTPSPSSSSARTSRHRMITASGPRAGNKRSAGGGGSGSSASTSSPAPGVPAKKVSTAASKVGTSSSYLNYGVDAYNVNVPASASAADVGSGFFSISEVVSAADAADAAAKAAAAGKTERKTRCFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480304;
90% Identity: iTF_00617778;
80% Identity: -