Basic Information

Insect: Drosophila bocki
Gene Symbol: zfh1
Assembly: GCA_008042715.1
Location: VNJY01001298.1:105953-108510[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 6.8e-05 0.0049 17.1 0.6 2 23 16 37 16 37 0.97

2 7 3.1e-06 0.00022 21.4 6.3 1 23 46 68 46 68 0.99

3 7 0.00018 0.013 15.8 1.2 3 21 76 94 74 95 0.94

4 7 0.0042 0.3 11.5 0.7 2 21 327 346 326 347 0.92

5 7 8.2e-06 0.00059 20.0 0.5 1 23 671 693 671 693 0.94

6 7 3e-05 0.0022 18.2 7.4 1 23 699 721 699 721 0.98

7 7 0.0015 0.11 12.9 4.3 1 21 727 747 727 748 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	6.8e-05	0.0049	17.1	0.6	2	23	16	37	16	37	0.97
2	7	3.1e-06	0.00022	21.4	6.3	1	23	46	68	46	68	0.99
3	7	0.00018	0.013	15.8	1.2	3	21	76	94	74	95	0.94
4	7	0.0042	0.3	11.5	0.7	2	21	327	346	326	347	0.92
5	7	8.2e-06	0.00059	20.0	0.5	1	23	671	693	671	693	0.94
6	7	3e-05	0.0022	18.2	7.4	1	23	699	721	699	721	0.98
7	7	0.0015	0.11	12.9	4.3	1	21	727	747	727	748	0.96

Sequence Information

Coding Sequence: atgtcagctgctgctgcgacgcTGCTGGCGTCGCAGTTGGCAGAGACCTGCCGGATCTGCCAGAAGGCGTTCGCGAATGTGTATCGCCTGCAGCGTCACATGATCAGCCATGATGAGAGCGCTCTGCTGCGAAAGTTCAAGTGCAAGGAGTGCGACAAGGCCTTCAAGTTCAAGCATCACCTCAAGGAACATGTCCGGATCCATTCCGGGGAAAAGCCCTTTGGCTGCGACAACTGCGGCAAGCGCTTCTCCCACTCGGGCAGCTTCTCCTCCCACATGACGTCCAAGAAGTGCATCAGCATGGGCCTCAAGCTGAACAACAACCGTGCTCTGCTCAAGCGTCTGGAGAAGAGTCCCGGTTCCGGAGGCGGCGCTCGTCGCTCCCCCTCCGATCAGGGCCTCAAGCCGGAACAGCAATCGGGCCTTCCGGGACTGCCCAATCCGATGATCTACTTTGCCAGCGATGCTCAAGGCCAGGCGGGAAATGCAGCTGCTACGCCCTTCCAACCCTTCCATCCCACGAACTACATGAATGCGGCTCTGTTTTCCTTCCCCAATCCCTTCATGGCTGCCGCCGCTTTGGATCCTCGCGTTCATCCCTACAGCATCCAGCGACTGCTGCAACTTACGGCTGCAGGTCAGCAACAgagggaggagcaggagcagcaacagcagcagcagctggagcaggaggagcgtGAGCCCGAGGAGGAGACGCCGGATGAGCCCAAGCTGGTCATGGACATTGATGAGCCGGAGACCAAGGATCTAAGGGCACCCACACCCGAAATCCGAGAGCCGGCAGCGGCTCCCATTAAGCAGGAGCTCAGCAGGGAAGCCTCTCCAGTTCCTGAGAGTGCTCCAGCTTCGCCGCAGGAGATCAAGCAAGAGCAGGTACAGGAACCGCTGTCGGTAGAAGAAGTAGAGCCACAGTCCTCGGTTGAAGAGCCCTCCCAAATAGAGCAACCCGCCGATCTGCGCTGCAGTCGCTGCTCCAAGCAGTTTAACCACCCAACGGAGCTAGTGCAGCACGAGAAGGTGCTGTGTGGCCTGAtcaaggaggagctggagcagcacttccatcagcagcagcagcagcaacaactacagCACCAGACCACGTCCTTTGTGATGCCCTCCGCCAGCGAAGAAGACGATGAAGACGAGGAGATGGAAGAGGAGCCGCGACAGGAGAGCGGCGAGCGCAAGGTGCGAGTGCGTACGGCCATcaacgaggagcagcagcagcagttgaaGCAGCACTACTCCCTGAACTCGCGACCCAGCAGGGATGAGTTCCGAATGATAGCCGCTCGCCTGCAGCTCGATCCGCGCGTAGTCCAAGTCTGGTTCCAGAACAATCGATCTCGCGAGCGAAAGATGCAGAGTTTCCAGAGTAATCAAACCACGCCGGTAGCCGGTAACAATGAAGTGCAGACTTCGCAGGTTTCACGTGAGGATCAACCCTTGGATCTGTCCATCAAGCGAGATCTTTTGACGCCTAAAAGCGAGAGCTCGCCACCCTACATACCGCCTCAGACTACTGAGGCCCTGAATCCGGAGGCTGCCATCAATCTGAGCAGGAAGTTCTCCAGCTCCGCCTCGATGTCGCCAGCCTCGATTTCACCCTCATCCGCGGCAGCCCTGTACTTTGGCGCTGGCCCGCCGCCTTCGCCGCCCAACAGCCAACTGGAGGCCACTCCTCGTTCGGCCGGCCAGGCCTTCCCAGGACTGCCCTACATGCTGCCCATGCCCCGACTCCCCATGGAGGCCCTGTTCCAAATGCGTCCCGGTGGCGAATACGCCCCCAATCATCCCCTGATGAACAGTATTAAGCTGCCCGATTATCGCGGCACAAGTCTGAGTCCCGGCGGATCAGAGAAGCGTTCGTGGCGCGACGATGACTCGCGGATCTCCCATGAGGATGACTTCAGTGGTGGACTAATGCCGCCGAAGCCAAGGCGAGGCAAACAGGAGACCCATGGCCATGCCGGCGATCCCGATCTGCCCTTTGTGTGCGATCAATGTGACAAGGCCTTTGCCAAGCAGAGCTCATTGGCACGCCACAAGTACGAGCATTCCGgTCAAAGACCCTACCAGTGCATGGACTGCCCCAAGGCCTTCAAGCACAAGCACCACCTGACGGAGCACAAGCGTCTGCATAGCGGCGAGAAGCCCTTCCAATGCTCCAAGTGCCTGAAACGCTTCTCGCACTCGGGCAGCTACAGCCAGCACATGAACCACCGCTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MSAAAATLLASQLAETCRICQKAFANVYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRALLKRLEKSPGSGGGARRSPSDQGLKPEQQSGLPGLPNPMIYFASDAQGQAGNAAATPFQPFHPTNYMNAALFSFPNPFMAAAALDPRVHPYSIQRLLQLTAAGQQQREEQEQQQQQQLEQEEREPEEETPDEPKLVMDIDEPETKDLRAPTPEIREPAAAPIKQELSREASPVPESAPASPQEIKQEQVQEPLSVEEVEPQSSVEEPSQIEQPADLRCSRCSKQFNHPTELVQHEKVLCGLIKEELEQHFHQQQQQQQLQHQTTSFVMPSASEEDDEDEEMEEEPRQESGERKVRVRTAINEEQQQQLKQHYSLNSRPSRDEFRMIAARLQLDPRVVQVWFQNNRSRERKMQSFQSNQTTPVAGNNEVQTSQVSREDQPLDLSIKRDLLTPKSESSPPYIPPQTTEALNPEAAINLSRKFSSSASMSPASISPSSAAALYFGAGPPPSPPNSQLEATPRSAGQAFPGLPYMLPMPRLPMEALFQMRPGGEYAPNHPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDFSGGLMPPKPRRGKQETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00489979;
90% Identity: iTF_00613695;
80% Identity: iTF_00489277;