Basic Information

Insect: Drosophila bocki
Gene Symbol: prg
Assembly: GCA_008042715.1
Location: VNJY01005757.1:223782-225513[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.057 4.1 7.9 1.0 1 23 204 227 204 227 0.93

2 9 0.11 8.2 7.0 1.8 1 23 233 256 233 256 0.97

3 9 4.4e-06 0.00032 20.9 0.5 1 23 262 284 262 284 0.98

4 9 4.4e-09 3.2e-07 30.3 2.3 1 23 290 312 290 312 0.99

5 9 1.4e-05 0.001 19.3 0.5 1 23 318 340 318 340 0.98

6 9 7.3e-07 5.3e-05 23.3 0.7 1 23 346 368 346 368 0.99

7 9 6.5e-06 0.00047 20.3 0.9 1 23 416 438 416 438 0.96

8 9 1.6e-05 0.0011 19.1 0.3 1 23 443 466 443 466 0.91

9 9 0.17 12 6.4 1.2 1 23 470 492 470 492 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.057	4.1	7.9	1.0	1	23	204	227	204	227	0.93
2	9	0.11	8.2	7.0	1.8	1	23	233	256	233	256	0.97
3	9	4.4e-06	0.00032	20.9	0.5	1	23	262	284	262	284	0.98
4	9	4.4e-09	3.2e-07	30.3	2.3	1	23	290	312	290	312	0.99
5	9	1.4e-05	0.001	19.3	0.5	1	23	318	340	318	340	0.98
6	9	7.3e-07	5.3e-05	23.3	0.7	1	23	346	368	346	368	0.99
7	9	6.5e-06	0.00047	20.3	0.9	1	23	416	438	416	438	0.96
8	9	1.6e-05	0.0011	19.1	0.3	1	23	443	466	443	466	0.91
9	9	0.17	12	6.4	1.2	1	23	470	492	470	492	0.98

Sequence Information

Coding Sequence: ATGCACGCGGTGGTGAACACGTGCCGACTGTGCCACCGCGAGGTGGAAGCCGACTCCCCCAACATCTTCGAGAGCTCCCTGGAGTTCTGTAGTGAATTGTCCATTGCCGAGATCTCGCAGCATCTTTGGGCCGTACACTACGAGCGCCATGAGCTCTTGCCGGAGCTGGTGTGCCCGGAGTGCCTAGAGCTATTGTTCGATGCATTCGAGCATCGCAAGGGCATGCTGGAGCGGGAACAGAGGCTGCAGGAGCAGCTAAAGGACATGATGAAAACGGATCCCAAGTACCGGCCCGGCTTCAATGGCAATCCTGGTGAATTCGAACCGGAGGAGGACTGCGAGATTGTGGACGTGGATCCAGAAAAGCTGTCGGAGACCAGTGAAGAAGAGTTCCTGCCTTGCTCGGAGGGGGATTACGAAAACTTCgaggaagacgacgacgaagaggaggaggacttCGATGAGGAGGACGAAGAAGAGGGTCAGAATGGCGAGGACGCTGATATGCCTTTGGGCATGGATGCCGCCCAGATGGCGCATATGGAGGCGGAAATGAAAGGCAATAACGCTAATACTGATCCCAGCTCTGGGGTGAAACCTAAGCGTGCCTTCCTCTGTCAGTACTGCGATCTGGGCTTCACCTTGCCCTCCGAGTGCCAGCAGCACGAGAAGAGCGCCCACGACCCGGCTGCCCCGTACTGCTGCACCTTCTGCAACCTCCGAGTGGACGCTCGTACCACACTGATTTCGCACATCAAGTCGCTGCACGATGCCGAGCGTCCGTATGTTTGCGCGCAATGCCGGAAGGGATTCGTGCGTCGCTCCGACTTGAAGAAGCACACGATTGTGCACACGGGCGTGCGACCCTATACCTGCAACGTATGCTCCAAAAGCTTCTCGAGAAACACCAACCTGAACAAGCATATGCGCATCCACAGCGGCGTCAAGCCGTTCGTGTGCCAGCAGTGTCCGCGATCATTTCAGACGGCCGTGGAATTAATGAGGCACTCACGCTCCCACTCCGAGGTAAAGGCTTACCAGTGTGGCCGCTGTCCATACTCCTTTTCGCGCAAGGATAAGCTGATGGCGCACCAGCAAGTCCACACCAGGCGCGACATTGaagagcagcagaagcaatTGGGGCTTCTGCCGCCAGGAGAAGGTGACCTggcgcaacagcaacagctgcaACTCCAGCTTCAGGCCAAGCCAAAGGCTCCCACGCACTCGAAGTCTTCGCGCAATTTCCGCTGCGACGTTTGCGACAGGTCCTTCCAGAGAGAGCGCGACCTGCAGCGCCATAGAGCCCTACACATGGACACGCTGTTCGCCTGCAAGATTTGCAATCAGGGATTCAACCGGCGGGAGCAACTGCAGCGTCATGAACTGGAGGCTCATGGGCCTAGCTACACCTGCAGCATCTGCTGCATCAACTTTCTGTATCAGGTGGAGCTGGAGAACCATCTAAAAGTCCATCAACTGCAGCACAAAATGGCTCAAAGTGCCCAAGAGGCCATCAATGCTGCCGCTAGTCTGCCCCTCAAAAAGGTCGAGCAGCCGCCGGTGGCTGTAATGCCTCCGGTGATTCAGCCCTCGGCTGCCGAACTCTCCTTCTACAGCAACATGATTCCAACCATGAATCTTGGTTTCTACAGCGAGACTCGTCCGGAGGAGTAG
Protein Sequence: MHAVVNTCRLCHREVEADSPNIFESSLEFCSELSIAEISQHLWAVHYERHELLPELVCPECLELLFDAFEHRKGMLEREQRLQEQLKDMMKTDPKYRPGFNGNPGEFEPEEDCEIVDVDPEKLSETSEEEFLPCSEGDYENFEEDDDEEEEDFDEEDEEEGQNGEDADMPLGMDAAQMAHMEAEMKGNNANTDPSSGVKPKRAFLCQYCDLGFTLPSECQQHEKSAHDPAAPYCCTFCNLRVDARTTLISHIKSLHDAERPYVCAQCRKGFVRRSDLKKHTIVHTGVRPYTCNVCSKSFSRNTNLNKHMRIHSGVKPFVCQQCPRSFQTAVELMRHSRSHSEVKAYQCGRCPYSFSRKDKLMAHQQVHTRRDIEEQQKQLGLLPPGEGDLAQQQQLQLQLQAKPKAPTHSKSSRNFRCDVCDRSFQRERDLQRHRALHMDTLFACKICNQGFNRREQLQRHELEAHGPSYTCSICCINFLYQVELENHLKVHQLQHKMAQSAQEAINAAASLPLKKVEQPPVAVMPPVIQPSAAELSFYSNMIPTMNLGFYSETRPEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00492409;
90% Identity: iTF_00492409;
80% Identity: -