Basic Information

Insect: Drosophila bocki
Gene Symbol: ZNF212
Assembly: GCA_008042715.1
Location: VNJY01008099.1:1975-3976[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.85 61 4.2 2.1 1 20 120 139 120 140 0.92

2 10 0.00018 0.013 15.8 0.5 2 23 189 210 188 210 0.97

3 10 0.0002 0.014 15.6 0.9 1 23 236 257 236 257 0.98

4 10 0.00036 0.026 14.9 0.8 1 23 264 286 264 286 0.98

5 10 2.8e-05 0.002 18.4 0.5 1 23 313 335 313 335 0.98

6 10 7e-08 5e-06 26.5 0.9 1 23 341 363 341 363 0.99

7 10 0.00096 0.069 13.5 5.5 1 23 369 391 369 391 0.98

8 10 2.2e-06 0.00016 21.8 0.9 1 23 397 419 397 419 0.97

9 10 1.8e-05 0.0013 18.9 0.3 1 23 423 445 423 445 0.99

10 10 0.0053 0.38 11.2 0.1 3 23 474 495 473 495 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.85	61	4.2	2.1	1	20	120	139	120	140	0.92
2	10	0.00018	0.013	15.8	0.5	2	23	189	210	188	210	0.97
3	10	0.0002	0.014	15.6	0.9	1	23	236	257	236	257	0.98
4	10	0.00036	0.026	14.9	0.8	1	23	264	286	264	286	0.98
5	10	2.8e-05	0.002	18.4	0.5	1	23	313	335	313	335	0.98
6	10	7e-08	5e-06	26.5	0.9	1	23	341	363	341	363	0.99
7	10	0.00096	0.069	13.5	5.5	1	23	369	391	369	391	0.98
8	10	2.2e-06	0.00016	21.8	0.9	1	23	397	419	397	419	0.97
9	10	1.8e-05	0.0013	18.9	0.3	1	23	423	445	423	445	0.99
10	10	0.0053	0.38	11.2	0.1	3	23	474	495	473	495	0.98

Sequence Information

Coding Sequence: ATGTCAACGCACAACGAGCCCGAGGAGATTCAGCCCCACATCCATGTGGAGGACGGACTTTGTGGAACAACCCAGTCGCCCCTTTTTTACTGCGAGAGCTGCGGTAACATTTACGGAGACAATGAGGCTTACGCCAAGGACCACAGTCACCAATCTGGTTGTTGTGTCGGTGGGATCAAGAAAGAGCTTGAGTTTGTAGAGGAGTTCATTTCAGAGGAACAGACCGAGGTTCCAGCAAGTTTAGCCGAGGAGGATAATGAAGAGGAGATCCACGAGGCTGACGTTCCGCTCTGGGAGGTGGTAGATGACTCCATTAAAGCAGAAGAGAACGAGACTGACCCCACCCATTCAGATCGTTACTTTTGCTATGACTGCCACAGCATTTTCGAGAACAGGAGCAGTGCAGAGGACCATGTTTGTCCGCAGGCAGACACCGGCGGTGGTGGCTCTATACAGCATGCAGACGAGATTCCCGCCGGCACAGCTAAACCACCGACACGTCGGAAGTTGCCCAGCGTGGCCGCAAGGACAGACTCCAAGGGTAGTTCACAATCAACTGTTATTAGCTGTGAAATATGCAACACAGTTTTTAGTTCTGCCAAGTTTCTCAAGTTCCATATGCGCATTCATGAAAAGGTGGCTCCCAAGAGCATTCAAGACGCCCTTCCCGTGGGCGCCCATCAGCAGTACAGTAAGCTGGATCAGTTTTACTGCGAGATCTGCAACAAGAGCTTCGACGAAAACCTCCTGACGGTGCACAAGCAAATGCACCAGGAGACCGCCAAAGAGTTCATGTGTGGCATTTGTAACCGGCAATTCTTTAACTCAATAGACTATCAGATGCACCTCAAGATTCACCAGAAGCCGCGCGACTTGGAAGCCACAAGAATGCCCGAACACCGCAGCACTGCAGCTGGCGATAAGGAGAAGCCGGGCTTTCCCTGCCAGTACTGCGAGCGTGTGTTCTCTCGCCCTTATGAAAAGGTTAAGCACGAACGGGTGCACACGGGCGAGAAGCCCTACTCTTGCGAGGTGTGCGGCAAGACCTTCCGTGTCTCGTACTCGCTCACTCTCCATTTACGGACGCATACGAACATACGGCCTTATGTTTGCACGGTATGCAATAAGCGGTTCAAGTCCCACCAGGTGTACTCCCACCACCTGCGTATACACAGCACAGAGCGGCAGTTTGCCTGCGACATATGCTCAAAATCCTTCCGCACCTCGGTCCAACTCTATGCCCATAAGAATACCCACACCAAGCCATACCAGTGTGTTGTATGCAACCGCCCCTTCTCGTCAATGTACGCCGTAAGAATTCACATGCAAACGCATGAAGAGGAGAAGAataaaggaaatggaaaaggcGTAGTACAGGCTTCTACCAACAAGAGCCAACCTTCAGCGGGGAAATTCTGGTGCAGTTCCTGTGGAGCAGAGTATGCACGTATGTTTGCCCTGCGAATGCATATGAAGACGGCTCACGGCCTGACAGAGGAAGTCGTCATACAGCAGGAGGAGAATTCGTCGTCCGCCCTAGAGGATGTCCTTCCCAACGTAGTAGACTCCGAGACAGCGGTGCTTATAGCAGCCGCCGAGGCTGATGCAGCGTACATTAACGCTGTGGTAAACGCTGTAGACGTCGTGGGATCCGTGCCCACATACGAAGAGGTGGCTGTTGAATTCGATGTGGAGAACTTCCACAGTGAGGAAATCATCACGGACTGGCTTAAATAG
Protein Sequence: MSTHNEPEEIQPHIHVEDGLCGTTQSPLFYCESCGNIYGDNEAYAKDHSHQSGCCVGGIKKELEFVEEFISEEQTEVPASLAEEDNEEEIHEADVPLWEVVDDSIKAEENETDPTHSDRYFCYDCHSIFENRSSAEDHVCPQADTGGGGSIQHADEIPAGTAKPPTRRKLPSVAARTDSKGSSQSTVISCEICNTVFSSAKFLKFHMRIHEKVAPKSIQDALPVGAHQQYSKLDQFYCEICNKSFDENLLTVHKQMHQETAKEFMCGICNRQFFNSIDYQMHLKIHQKPRDLEATRMPEHRSTAAGDKEKPGFPCQYCERVFSRPYEKVKHERVHTGEKPYSCEVCGKTFRVSYSLTLHLRTHTNIRPYVCTVCNKRFKSHQVYSHHLRIHSTERQFACDICSKSFRTSVQLYAHKNTHTKPYQCVVCNRPFSSMYAVRIHMQTHEEEKNKGNGKGVVQASTNKSQPSAGKFWCSSCGAEYARMFALRMHMKTAHGLTEEVVIQQEENSSSALEDVLPNVVDSETAVLIAAAEADAAYINAVVNAVDVVGSVPTYEEVAVEFDVENFHSEEIITDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00613632;
90% Identity: iTF_00527483;
80% Identity: -