Dboc011768.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila bocki
Gene Symbol
sd
Assembly
GCA_008042715.1
Location
VNJY01003817.1:20378-30905[+]

Transcription Factor Domain

TF Family
TEA
Domain
TEA domain
PFAM
PF01285
TF Group
Helix-turn-helix
Description
The TEA domain is a DNA-binding region of about 66 to 68 amino acids that has been named after the two proteins that originally defined the domain: TEF-1 and AbaA. The TEA domain is located toward the N terminus of eukaryotic transcription factors of the TEA/ATTS family. It shows a three-helix bundle with a homeodomain fold [3, 1]. Two α-helices are nearly anti-parallel and pack on either side of the third one, which is the DNA-recognition helix of the TEA domain. Phosphorylation of one or both of the two conserved serines found on the DNA-binding surface could interfere with DNA-binding activity, by introducing electrostatic repulsion and/or steric hindrance, and help regulate the transcription factor activity of the proteins [2, 1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3e-31 4.9e-27 93.9 0.1 2 66 92 158 91 160 0.96

Sequence Information

Coding Sequence
ATGAAAAACATTACAAGCTCGAGCACTTGCAGCACGgggctgctgcaactgcagaACAACCTTggcagcgacggcggcggcgagtTGGACGTTGCAGAAAAACCAGAGGCGACAGttGGACCCGGCACCATACCATCACCGTGGACACCAGTAAATGCCGGTCCTCCAGGTGCCCTTGGATCGGCAGACACAAATGGCAGCATGGTGGATAGTAAAAACCTGGATGTTGGTGATATGAGCGATGATGAAAAGGACCTATCATCTGCTGATGCCGAAGGTGTCTGGAGTCCGGATATCGAACAGAGCTTTCAAGAGGCTTTATCTATATATCCACCATGTGGACGtagaaaaatcattttatcCGATGAGGGTAAAATGTATGGTCGCAATGAGCTGATCGCACGGTATATCAAACTGCGGACGGGCAAGACGAGAACCAGGAAACAAGTCAGCTCTCACATCCAAGTGCTGGCCCGACGGAAGCTGCGCGAGATCCAGGCGAAAATTAAAGTTGAGCCCAATGACGTGTCCTTGCACTTGTTAAACGAGAAAGAGCAGACGACCCTGCAGATCATGACCACAATGACCAGTTCGCAAATCGTATCCGCCCAGGCGGCCAACAATCTTGCCTTTGCTGCGTCGGCGTTATCGGTGCACCCGCATCCTCATCCCCGTCACCTGCCGGTGGGGTCCTCCTCCACCTCATCCCCGTTGGTCACCGGTCAGCCGCCGCTAATCTCGTCGTGCTCGCCCCGACAACAACACTATCATCCCCATGCGCACGTGCAAGCCCtccaccatcaccatcaccaccaccatcattCCCATCCCAACTTGACGCACATACCGCACAGTCATGTGCATCATCCTCATCCCCAtcctcatccacatccacaccATCCACATGCAGCAGCCGTGGCAGCGGTCTAccatctccagcagcagcagcagcaacagcagcagcgccagacAACTGCGCCGAGCGACTCTGTCACGGACTCCGGCTCTGGCTCAGGCTCTggttctggctctggctctggctccggcTGTGGCTCCGGTCCAGTGGTACGTTGTGCTGGCGGAGGCTCTGgtccaccgccaccaccaccacctccagcGACGCTGCACCACCCCCCGCCGCCGTTGTATTCGGGCCAATTCTGGCAGCCTGGACTGCAGCCGAGCACGTCACAAGATTTCTATGATTACAGCATCAAGCCCTTCGCACAGCCACCCTATCCAGCCGGCAAGCCATCGACGGCGGTGTCCGGGGATGAAACTGGAATTCCGCCAGCTCAATTGCCTTGGGAGGGACGAGCCATTGCCACGCACAAGTTCCGATTGCTGGAGTTTACGGCGTTCATGGAAATCCAAAGAGATGATATGtATAACCGTCACCTTTTTGTACAACTAGGCGGCAAGCCATCCTTCTCCGATCCGCTACTAGAGACTGTTGATATCCGGCAAATATTCGACAAGTTTCCGGAAAAATCCGGCGGGCTCAAAGATCTCTACGAAAAGGGGCCACAAAATGCGTTCTATCTGGTTAAATGCTGGGCAGATCTTAATACCGACATAACGACTGGCAGCGAAACGGGCGATTTCTATGGCGTAACCAGCCAATATGAGAGCAACGAGAACGTGGTACTTGTCTGCTCTACGATCGTTTGCTCCTTCGGAAAGCAGGTGGTGGAGAAGGTGGAGAGCGAGTATTCGCGGCTGGAGAATAATCGTTATGTATATCGCATACAGCGCTCACCCATGTGCGAGTATATGATCAACTTTATACAGAAACTGAAAAACTTACCTGAACGCTACATGATGAACAGTGTGCTGGAAAACTTTACAATATTGCAAGTAATGCGAGCGCGTGAGACGCAGGAGACACTGCTTTGCATTGCCTACGTTTTTGAGGTGGCGGCTCAGAACAGCGGCACCACCCACCACATCTATCGTCTCATCAAGGAATAG
Protein Sequence
MKNITSSSTCSTGLLQLQNNLGSDGGGELDVAEKPEATVGPGTIPSPWTPVNAGPPGALGSADTNGSMVDSKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIKVEPNDVSLHLLNEKEQTTLQIMTTMTSSQIVSAQAANNLAFAASALSVHPHPHPRHLPVGSSSTSSPLVTGQPPLISSCSPRQQHYHPHAHVQALHHHHHHHHHSHPNLTHIPHSHVHHPHPHPHPHPHHPHAAAVAAVYHLQQQQQQQQQRQTTAPSDSVTDSGSGSGSGSGSGSGSGCGSGPVVRCAGGGSGPPPPPPPPATLHHPPPPLYSGQFWQPGLQPSTSQDFYDYSIKPFAQPPYPAGKPSTAVSGDETGIPPAQLPWEGRAIATHKFRLLEFTAFMEIQRDDMYNRHLFVQLGGKPSFSDPLLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDITTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHIYRLIKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00590197;
90% Identity
iTF_00593795; iTF_00612771; iTF_00485094; iTF_00488623; iTF_00491471; iTF_00541031; iTF_00609130; iTF_00525841; iTF_00561716; iTF_00590197; iTF_00524375; iTF_00477977; iTF_00606265; iTF_00482938; iTF_00480123; iTF_00613468; iTF_00492190;
80% Identity
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