Dbir001029.1
Basic Information
- Insect
- Drosophila birchii
- Gene Symbol
- -
- Assembly
- GCA_008042755.1
- Location
- VNKA01001717.1:273366-278779[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00034 0.028 15.0 1.3 2 23 153 174 152 174 0.97 2 13 0.00012 0.0096 16.4 1.9 1 23 399 421 399 421 0.98 3 13 3.8 3.1e+02 2.2 2.3 1 23 427 450 427 451 0.92 4 13 1.8 1.5e+02 3.2 3.9 1 23 473 496 473 496 0.93 5 13 0.0011 0.091 13.3 1.9 3 23 824 844 823 844 0.92 6 13 0.045 3.6 8.3 1.4 1 23 850 873 850 873 0.98 7 13 0.0037 0.3 11.7 0.5 1 23 953 976 953 976 0.97 8 13 0.00079 0.064 13.8 0.2 1 23 1174 1197 1174 1197 0.94 9 13 0.017 1.4 9.6 5.0 1 23 1209 1231 1209 1231 0.98 10 13 1.1e-06 8.7e-05 22.8 0.5 2 23 1235 1257 1235 1257 0.97 11 13 0.0013 0.1 13.2 0.8 3 23 1265 1288 1263 1288 0.88 12 13 0.01 0.83 10.3 0.2 1 23 1293 1315 1293 1315 0.96 13 13 0.0031 0.25 12.0 0.5 1 23 1321 1344 1321 1344 0.97
Sequence Information
- Coding Sequence
- ATGGCATTGAATAAGCGGATTAACCCGAATTCGGACGCCCGGGAGGGCGTCACGGAGTTGAACTACAAGTTTGCGTGTCGCTGCTGCCTGAAGTCGGACGCCGAGTTCATAAGGCTGGACTCGACGTCGGTGGCGCGCAGCCTGGACCCAGCCAGCGAGGAGGATAAGATTTCGCTCTTGCGTTGCCTTCTCTTCTGCGTGCGAGCGGAGAACGCGCCCGAGCTGCCGCCGTACATCTGCCTCGAGTGCAGCAAGAGCCTGCAGGTCGCCTACTACTTCCTGCAAAATGCAGTGCGTGCCCACGAGATCCTGTGCCGCAAGCTGTGCCCAGCCAAAGCATGGCAAGCGGAGGGCAAGCGTCTAAATGGGGCCATGGGCCAGCGCTTTCAACCATCGCCGTCTCCCAAGGAGgcggcggcggcggacaaGACGAGGCCCCCAAAGAGCATGCGACAAGAGTGCCAGGTTTGCGGCGAGATCTTCCACAGTCGCATGGAGCTCAAGCAGCACCTCCGCCAGCACACAGACGGCATTTCGTACCACTGCAAAATGTGCAACTTTACCACGCTGAAACAGCGGCAGCTACTGGATCACTATCGCTGCGATCACTCCATGACTCCCAGCCAGGCGGAGGAGCACCTTAAGGCGAGTCCACAACCCAAATCTTCCATAAAGGAAGAGGAGGTCAAGGCAGTGTGCACGCTGGAGGATATGGAGCTGCTAATACCCACGGTGCTCACGCCGGACGATTACGCTCAGCCCACAATTGATTCGGATCAGCTGCGCGATctcgagcagcagctggccgTCAGCATGGGCGATACAGTGACGGGAGTGGACAGCCTAACATCCACATTGCCGCCCATGGACACGGCACACAATGTGAGCATCGGCACCGAGTATCTGGTACTGCCGGATGGATCCCTGCAGCAGATCAACGGAGGCGGCGTGGTCATTGAGTACATTGACGACAGCAGGACGAAGACGCCGCCACCTCCACCTGCTCAAAATTCTCCGCATATCAACATCAATCTTCAAAACCTGCTTGGCCCCGAGGAAAACGACGCGATGGATATCGATGTCAACGACCACATTGTCGAGGATATGATGAAGATACAAAAGCCCACAATTTCTACTGCAACTTCCAACCCAGCCAAGCCAAGGCCAACGATTGGCGGATCCGCCAACTTCAAGCACAAGTGCAGTATATGTCCCAGGACGTTCTCATCAGTGCCGCGCCTGAAATCCCACCAGTTGACCCACAGCAATTTGCCCAAGTTCTTCTGCGACCAGTGCGATTTCTACTCGCTGCGCAGCGTCGATCTCATCGAACACTACAAGACTACGCACCATCGGGTGGATGAGAACGGTGCAACCAGCCAGGACCCAGGCCCGGAGTCGGAGGAGACGGGCGTCTATTCGTGCGACATGTGCCTCTTTGAGACGCGCACATGCCGCCAGCTAAGGGTGCACTATACGCAGCGGCACGCGATCCAGCCCACAGAAGTGCAGCTGCGTCCCAGTTGGACGAACAATGCTGGCAATGGGACTAACAACAGGGAGCAGCCGTTGTCAGGCAGGATGCCAGAACCCGCCGATCTGCCGGTGGCCATTAAATacCCGCCCCTAGTTTCGGATGCGCAGGTTCCAgtgcaaatgcagcagcaagtccaagtgcagcagcagcagcagcaacaggtggTGGCCACCACACCCACAACGCTCATCACACAGACGAGCAACCACATCAACGTGGTGGTGGATACCACACCGCTCTTCTATGCTTCAACCGCTTCCAGTGCCGTGCAGGCAGTGCCAGTGCCGGTCCAGGCCATGCCAGTGCAGGTGCAGGCCATGTCAGTGCCAGTGCAGGTCATGACAGTGCCGGTACAGACCATGCCCGGGCCGGAACAAACCATGCCAGTGGCAGTGCCAGTGCAGGCCATGCCTGGTCATTCGCCAGTGACAGCTGTGATGCAGCAGCCCACCCACAACGAGGATAATAGCAATGCATTCGAAATCCAAAATTCATTTCCAAAAGTCCCACCAAGCGATGAGCAAGTGGATGAACCCGTTCCCGTCGAGCCAATTCCGACGGCCAACACTTCCAATATCTCAATGTTCGGAGATATGCAGGATTTCATTGATAACACCGATGTGGCTGCCATATGCACGATACCAGCGGACGATATGCCCGTGGTGGATGGCGACGATATTGTGATtgataataacaatattaGCCTGGACTTTGATGCCGAAAATCTGTTTGAGGAATTCGAAGAGGAGGACGAGACTGTGGGCGAAGACGAGGGCgaggagggggaggaggaggaagaggacgaGGCGGACAATGATGATGAGAATGACAACAACGATGCGGCCACAGATCAAAATCTTCTGCTTACCagcgacgatgatgatgtggACGATTTTGACGATGAGCAATCGAAGCATCTGCAAAAGCCGTACTGCATTTATTGCAACAAGAAGTTCACCAGTCAATACAAGTTCGAGAATCATATGTTTGTCCATCGGGGCCTGGCTCCCTATCGCTGTGAGCTGTGCACCAACCTCTACAACATGAAGCGCCTGCTAATTAGGCACTACAAAACAGTGCACAAGCGAATGCCCACCAGAGACATGGTGCAGGCTAAGGGCGATAAGGTGCTGGTGGAGCGTACCAACATAGAGAAGCTTTATATAGATTCCATCAAAActccCATGGTGATGTGCGCCAAGTGTCCGTTTGAGTGCGAGGCGGATGGTGAAATGCGAAAGCATTTGAATGCCCATCACGGCATAAATGATGGACTGTCCATTCATGCCAATGAGGTCTTCATTATACGCAAATTGCCGTTTGAGTGTCCGCGCTGTATTCGATCGTTTGCTGCCAAGGGCAAGCTTACCCGCCACTTGCAGCGCAGCCATTTGGTGGACACTATTATTGAGATGCAAACGCCGCATTCGTCggctgccaccaccaccatcacaaCAACGACGGCCACTATAGCCGGGCCAGCGGGAGATAAGGAATCTTTTAGGGacgagatgatgatgatgacgacaacAACGACGGCTGCTGCAGGCAATGcaGAGCTGGGAGTAAGCCAGGATGATCAGGATggatcatcagcagcagcgccagtaAGAAGAGGGCGCGCCGTGCCGGATGAGGATGTGGATCCGGTGACATTGGACGCAGCCACGGCGGCGACAACAGCTGCCATAGCAGCGGCCATatcatccgcatccgcatcgcccagcgcaacaacaacaggcatGGCACCTTCCGCATCCAACCTGTATCCCACTCCCACGCCTTTTGATTTCGACTATGACTTAATGGGCAGTGATGCGCAGCGATCCCAGGTATCGACGCCCACTTCCAATCCCCAGCTCGGATCGCCTGGCAGCGGTCTGCTTAATGGCAGTGACAAGCTGCTGACAACCGCCGCCATGACCCCATTCCCAACGAAGGATCTGCGCTCCAACAGACGGCAGACGGCGTATAGTTCGATCTATGTATGCAAGCTGTGCAACAAGTCCTTCGACGAGCTGGGCAAGCTGGTCAAGCACGAGATGGAGATCCATTCAAATACGGAGCCCTCGCGATGGGGCTACCAGCACAAGTGTTCCATCTGCAGCACCAGCTACCGCACGCTGACACTGCTCAAATTCCACATGAAGCGGCACATCAACCGGCAGTGCAAGCTCTGCCCCAAGAGCTTCGCAAACAACGCGGAGCTGGAGAAGCACATGAAGGTGAAGCATTGCCGCGAGAAGTTGATCCCGTGTGCAATCGATGGCTGCGGGAAGATGTTCGCCTTTAAGCATCATATGATCCGGCATCAGAACGCCTCACATCTAAAAACTCGCCACATATGCGATGTTTGCAATAAGGAATTGATGAACGTGGCGGACTTGAAATCGCACATGATACTGCACAAGAGCTTGGTTACCTACAGGTGTCCCGAGTGCGACCGCACATATTTGCGGCGCGGAAGACTTCTGACTCATCTACTGAAAATTCACAAGAAACGCCTAACCGAAGACGAGATAGCCGCCTATAAAGAAGACCCAAGCCCGCCACAAAGTCCGGCCCAAAGCCCGAACGATCTGACCAGGCAACTGGGGCTCCACTATGATGTGGAAGAAACTGTAATCAAGGAAGAGGCGCATCCGGATGCGAtatcggcagcggcagcggcagcggcagctaaTCTTTCCAAATAG
- Protein Sequence
- MALNKRINPNSDAREGVTELNYKFACRCCLKSDAEFIRLDSTSVARSLDPASEEDKISLLRCLLFCVRAENAPELPPYICLECSKSLQVAYYFLQNAVRAHEILCRKLCPAKAWQAEGKRLNGAMGQRFQPSPSPKEAAAADKTRPPKSMRQECQVCGEIFHSRMELKQHLRQHTDGISYHCKMCNFTTLKQRQLLDHYRCDHSMTPSQAEEHLKASPQPKSSIKEEEVKAVCTLEDMELLIPTVLTPDDYAQPTIDSDQLRDLEQQLAVSMGDTVTGVDSLTSTLPPMDTAHNVSIGTEYLVLPDGSLQQINGGGVVIEYIDDSRTKTPPPPPAQNSPHININLQNLLGPEENDAMDIDVNDHIVEDMMKIQKPTISTATSNPAKPRPTIGGSANFKHKCSICPRTFSSVPRLKSHQLTHSNLPKFFCDQCDFYSLRSVDLIEHYKTTHHRVDENGATSQDPGPESEETGVYSCDMCLFETRTCRQLRVHYTQRHAIQPTEVQLRPSWTNNAGNGTNNREQPLSGRMPEPADLPVAIKYPPLVSDAQVPVQMQQQVQVQQQQQQQVVATTPTTLITQTSNHINVVVDTTPLFYASTASSAVQAVPVPVQAMPVQVQAMSVPVQVMTVPVQTMPGPEQTMPVAVPVQAMPGHSPVTAVMQQPTHNEDNSNAFEIQNSFPKVPPSDEQVDEPVPVEPIPTANTSNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEEFEEEDETVGEDEGEEGEEEEEDEADNDDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVLVERTNIEKLYIDSIKTPMVMCAKCPFECEADGEMRKHLNAHHGINDGLSIHANEVFIIRKLPFECPRCIRSFAAKGKLTRHLQRSHLVDTIIEMQTPHSSAATTTITTTTATIAGPAGDKESFRDEMMMMTTTTTAAAGNAELGVSQDDQDGSSAAAPVRRGRAVPDEDVDPVTLDAATAATTAAIAAAISSASASPSATTTGMAPSASNLYPTPTPFDFDYDLMGSDAQRSQVSTPTSNPQLGSPGSGLLNGSDKLLTTAAMTPFPTKDLRSNRRQTAYSSIYVCKLCNKSFDELGKLVKHEMEIHSNTEPSRWGYQHKCSICSTSYRTLTLLKFHMKRHINRQCKLCPKSFANNAELEKHMKVKHCREKLIPCAIDGCGKMFAFKHHMIRHQNASHLKTRHICDVCNKELMNVADLKSHMILHKSLVTYRCPECDRTYLRRGRLLTHLLKIHKKRLTEDEIAAYKEDPSPPQSPAQSPNDLTRQLGLHYDVEETVIKEEAHPDAISAAAAAAAANLSK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00524667;
- 90% Identity
- -
- 80% Identity
- -