Dbir015662.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila birchii
Gene Symbol
-
Assembly
GCA_008042755.1
Location
VNKA01005600.1:100161-103129[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.42 34 5.2 4.2 1 23 175 198 175 198 0.96
2 9 1.4 1.1e+02 3.6 1.4 3 23 252 273 251 273 0.90
3 9 0.0002 0.016 15.7 5.2 1 23 625 647 625 647 0.97
4 9 0.00027 0.022 15.3 0.3 1 23 653 675 653 675 0.98
5 9 0.00049 0.04 14.5 0.9 1 23 681 703 681 703 0.98
6 9 2.1e-07 1.7e-05 25.1 0.5 1 23 709 731 709 731 0.99
7 9 7e-06 0.00056 20.3 0.6 1 23 737 759 737 759 0.99
8 9 2.5e-06 0.00021 21.7 0.6 2 23 766 787 765 787 0.97
9 9 7.1e-05 0.0057 17.1 0.4 1 23 793 816 793 816 0.96

Sequence Information

Coding Sequence
ATGCTGAAAATGACAAATGTTGCTGGGCCGCTGCAAATAATGAAGAAAAACGCAAAtggcaacgacaacgacgactcCGAGGAGTCCGACATAGACatggatgaggaggaggaggaggaggaagaggaggacgaTCTGCCCGACGATGTGGTGCTACAGATCGACAGCGAGGACGAGGCGGAGCTGGAGGCGCAGCGCATTCGCTTGGTGCgcgaagaagaggaagaggccaaggccaagaccaagacagcaacagcaaccacaAAGCAGGAAAATAGAGAAGCGCAGGTCAGTAACGGTAAAGCGAATGGCGTGGTGAagaaggaggcggaggagaagTCGGAGCTCGGAACAACGAAGTCCGGAAAGGCGGCTACCAAACGCAAGGCACGCGGCAAATCCGGTCGCCGGGTTTCTGAGAGTTCGCAGGCCTCCAGTGTCGGCTCCGTTGCATCCAGCGCAAGCGTCGCCTCCTTGGTGGCCGCCCAGGTTCTGGCCGACGAGAAGGCGCGCAGCTTCATTTACAGCTGCACGCAGTGCAGTCATCATTACGCCGACCGTGTGGTCCTCTCACGGCACTTCCAAAAGGAGCATGCCGAGAAGCCCAAGCGGAAGCGTGGACGAAGCAAGCTTGTCAGCCCCGAAGAGGATACATCTGCTGTTTTAAGTCCTCTAACCCTCCTGCCAGAGGATCTGAGCCAACTCAAGCCCTGCGCCCAATTGCTCATGCAGGGCGAGTCCGTGCTGCAGCTGTGCCTGGCCTGCAACTCACAGTTTGTGGACCAGCAGCACTTCCAGGAGCATCTTAGCCAGCAGCATGGTTTCttcaagctgctgctggtgcccaAGGAGGAGCCCACCGATCTGCCGCCACTGGCCATGGTCACCATTCCGGGGGCTCTGGCCTCAGTCAAGTCCAAccagcagcttcagcttccCATCCCAGCCCCAGAGACCCCACCGCCCGAGCAGGATGTCAAGGAACCGATAAGGAATACACAATCCAATGGCAGTGTGGTGGCGTCTAACGATAAGGAAGGTCTCCATATGATAAGCGCCATGGTGGCCGAGATTGCGGCCGAGAGAGTCAAGAAGACCAGCAGTCCCAAGGTCAGCAAAATCATCATCAAGGTGCCAAAGGCGGCCAACAAAAGGGGCAGAAAACGCGCCAAGCCGGAGAAGACAAAGATTCGGGATATAGCTGaaatgctgcagctgcaggcgGTGAAATCAGAGAGCGATCAACCTAAGGCGGAGCACACACACCAAGTGGAGACAAAGAAACCCGATCTAGCAGCTGAGGATCAGGGAGCTGTTGAGATTCCTCGGCAGTTAGGTAAAGCTGACAAAGAAAAGCATGAGAATATTGCTATTGAGGATAATTTGGAGAAAATGGAAGCGGATCATCAGCAGCCAAAGAAATCTGAAGGAGAGCCAGAGGAAATACAGCAGCCAATGGAAGTTAAGGGTCTTCTACAGCCGGAAAAGTTAAAGAAGTCTCAACAGCCACAGAAATCAAATacggagaaggagcagcagccatcATCTGAGCCAAATCATAATCCATCCAAGCGCAAGCGCGGCCGCAAAGAGCAAAAATCGCCAACGCCCATAACCGTCCCGTTGGAAGACAAAGAAATTAAGGAGGAGACTGAAACCACAGAGCGGCGCATGCGTAAAAGCCGCAACTTTGCGGACTACGCAGCGGATATTAAGGATGAAGAAGAGAACAATGAAGGGGAGGAGCCAGAGCTGGATGGGGACTCCTCGGCCACAGTTTCGCCAAACACTAGCTCCGCGGATGACAGTTTCACCTCGATCAAACGTGAATCATCCGTGGATTCGCAGCATAACGAAACCGGAGGCAGCATACACACCTGTAATTTCTGCGGCAAGACGTTTAAACGCTTCTCCCGGATGCAGGATCACCTGCGTCTCCATACCGGCGAGAAGCCCTACGTTTGCGGACAGTGCGGCAAGGCATTCCGCTTGAAAATGCGCCTGGTAGAGCATCAACTGCGCCATCGTTCCGAAAAGGCCTTCAAATGCGAGATCTGTTCAATGCCACTGGCCACCAAGCAGGATCTGTCCCTCCACATGCGTCACCATCAGAACGACAAACGCTACAAATGCGACAAGTGCAACAAGGCATTCGTCCGAAGCTCCGATTTGTCCATCCATGTCCGGATTCATACGGGTGAAAAGCCCTACAGCTGTGACATTTGCAGCAAGGCATTCCGGGCGCGCCAGAATCTTGTTGTCCATCGACGCACTCATCTCGGTGACAAGCCCATACAGTGTGACCTGTGCGACAAGCGCTTCGCCAGAAAAATCGATATGCGGGTGCACATGCGCAGGCATACTGGGGAAAAGCCCTACAACTGTGATTTATGCCAGCGCGGCTACTCCTCACGAGTGAATCTGGCACGTCACCAGGAGCGCGAACATGACCAGAAGGAGGAAAAGAGCTCTGGATCTGGCTCTGGCAAAGCTGAGAAGAAAAAGTTggaaaaggagcaggagaagaaaCCGCAACCCAAAGCCAAAGCGGCgccacgacgcccccgacgTGAGAAGCTGCAGCAGAAGATTGTGGCCCAGGAAAAACTACTGGACGATCTGAAGCGCAGCTTGGGCACATTGCCGGAAATAACCGAGGAAGAGTCATCATCTCAGGTAAAGTTGAATGCCGGGAAACTTCCAGCAGATGCCGGAGCAGGGCTTGCCCAAGTTCAAGTCACGGTGTCCATGCAGATGGAGCCCGCACCCAGTCACGAAGACGATGAGGAAATCACACCGGAAAAGGAGAACGCACTGTCCAGCTCGACTGCGTCGGCGGCCGACAAGACAAAGGCAAATCGCAAGATCACCAGCTACTTCACAGTCGTAGGTCAGCAGGCGGAAATCTAA
Protein Sequence
MLKMTNVAGPLQIMKKNANGNDNDDSEESDIDMDEEEEEEEEEDDLPDDVVLQIDSEDEAELEAQRIRLVREEEEEAKAKTKTATATTKQENREAQVSNGKANGVVKKEAEEKSELGTTKSGKAATKRKARGKSGRRVSESSQASSVGSVASSASVASLVAAQVLADEKARSFIYSCTQCSHHYADRVVLSRHFQKEHAEKPKRKRGRSKLVSPEEDTSAVLSPLTLLPEDLSQLKPCAQLLMQGESVLQLCLACNSQFVDQQHFQEHLSQQHGFFKLLLVPKEEPTDLPPLAMVTIPGALASVKSNQQLQLPIPAPETPPPEQDVKEPIRNTQSNGSVVASNDKEGLHMISAMVAEIAAERVKKTSSPKVSKIIIKVPKAANKRGRKRAKPEKTKIRDIAEMLQLQAVKSESDQPKAEHTHQVETKKPDLAAEDQGAVEIPRQLGKADKEKHENIAIEDNLEKMEADHQQPKKSEGEPEEIQQPMEVKGLLQPEKLKKSQQPQKSNTEKEQQPSSEPNHNPSKRKRGRKEQKSPTPITVPLEDKEIKEETETTERRMRKSRNFADYAADIKDEEENNEGEEPELDGDSSATVSPNTSSADDSFTSIKRESSVDSQHNETGGSIHTCNFCGKTFKRFSRMQDHLRLHTGEKPYVCGQCGKAFRLKMRLVEHQLRHRSEKAFKCEICSMPLATKQDLSLHMRHHQNDKRYKCDKCNKAFVRSSDLSIHVRIHTGEKPYSCDICSKAFRARQNLVVHRRTHLGDKPIQCDLCDKRFARKIDMRVHMRRHTGEKPYNCDLCQRGYSSRVNLARHQEREHDQKEEKSSGSGSGKAEKKKLEKEQEKKPQPKAKAAPRRPRREKLQQKIVAQEKLLDDLKRSLGTLPEITEEESSSQVKLNAGKLPADAGAGLAQVQVTVSMQMEPAPSHEDDEEITPEKENALSSSTASAADKTKANRKITSYFTVVGQQAEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00492416;
90% Identity
iTF_00478184; iTF_00541241;
80% Identity
-