Basic Information

Insect: Drosophila birchii
Gene Symbol: prg
Assembly: GCA_008042755.1
Location: VNKA01000639.1:164803-166532[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.017 1.3 9.7 0.8 1 23 203 226 203 226 0.94

2 9 0.028 2.3 8.9 2.7 1 23 232 255 232 255 0.97

3 9 1.8e-06 0.00014 22.1 1.0 1 23 261 283 261 283 0.98

4 9 8.2e-09 6.7e-07 29.5 1.9 1 23 289 311 289 311 0.99

5 9 5.6e-06 0.00045 20.6 0.6 1 23 317 339 317 339 0.98

6 9 1.3e-06 0.0001 22.6 0.7 1 23 345 367 345 367 0.99

7 9 7.9e-06 0.00064 20.1 1.0 1 23 416 438 416 438 0.96

8 9 1.6e-05 0.0013 19.1 0.3 1 23 443 466 443 466 0.91

9 9 0.18 14 6.4 1.2 1 23 470 492 470 492 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.017	1.3	9.7	0.8	1	23	203	226	203	226	0.94
2	9	0.028	2.3	8.9	2.7	1	23	232	255	232	255	0.97
3	9	1.8e-06	0.00014	22.1	1.0	1	23	261	283	261	283	0.98
4	9	8.2e-09	6.7e-07	29.5	1.9	1	23	289	311	289	311	0.99
5	9	5.6e-06	0.00045	20.6	0.6	1	23	317	339	317	339	0.98
6	9	1.3e-06	0.0001	22.6	0.7	1	23	345	367	345	367	0.99
7	9	7.9e-06	0.00064	20.1	1.0	1	23	416	438	416	438	0.96
8	9	1.6e-05	0.0013	19.1	0.3	1	23	443	466	443	466	0.91
9	9	0.18	14	6.4	1.2	1	23	470	492	470	492	0.98

Sequence Information

Coding Sequence: ATGGTCGTGAACACGTGCCGCCTGTGCCACCGCGAGGTCGAGGCCGACTCCCCCAACATTTTCGAGAGCTCCATGGAGTTCTGCAAGGAATTGTCTATTGCAGAGATCTCGCAGCATCTTTGGGCCGTTCACTACGAACGCCATGAACTATTGCCGGAGCTCGTGTGCCCGGAGTGCCTGGAGCTGTTGCTAGATGCATTCGAGCAGCGTAGGGGCATGCAGGAGCGAGAACAGGGACTGCAGGAGCAGCTAAAGGAGATGATGAGAACGGATCCCAAGTACCGGCCCGGTTTTAATGGAAATCCTGGTGAATTTGAGCCGGATGAGGACTGCCAAATCGTGGACGTGGATCCGGAAAAACTGTCAGAGACGAGTGAAGAAGAATTCTTGCCTTGCTCGGAGGGCGATTACGAAAACTACGAGGAAGACgatgaggaagaggaggaggatttcgatgaggaggacgaggaagaGGGTCAGAATGGCGACGATGTTGACATGCCACTGGGCATGGACGCCGCTCAGATGGCCCTCATGGAGGCGGGAATGAAAGCAAATAACATTAATTCCAATCCAAATTCTGGATTGATAAAACCCAAGCGCGCCTTCCTCTGCGAGTACTGCGATCTGGGCTTCACCTTGCCCTCAGACTGCCAGCAACACGAGAAGACCGCCCACGACCCAGCAGCGCCGTATTGCTGCACCTTCTGTAATCTCCGGATGACCACCCGAACCGCTCTGATTTCGCACATAAAGTCGCTGCACGATCCCGATCGTCCGTATGTGTGCACGCAGTGCCGGAAGGGATTCGTGCGACGCTCCGACTTAAAGAAGCACACGATTGTGCACACGGGCGTGCGTCCCTATACCTGTAACGTGTGTTCAAAGAGCTTTTCGAGGAACACTAACCTGAACAAGCACATTCGCATCCACAGCGGCGTCAAGCCCTTCGTTTGCCAGCAGTGTCCGCGATCTTTTCAGACGGCCGTGGAATTGATGAAGCACACGCGCTCCCACTCCGAGTTAAAGGCTTACCAGTGTGGCCGCTGTCCGTACTCCTTTTCGCGCAAGGATAAGCTGCTGGCCCATCAGCAAATCCACACCAAGCACGACattgagcagcagcaattggGACTCCTTCCACCTGCGGATGGCGACCTGGCGCAActccatcagcagcaacagctacaGCTGCAGTTTCAGGCCAAGCCGAAGGCTGCACCGCAATCAAAGTCCTCACGTAATTTCCGCTGCGATGTCTGCGACAGGACTTTCCAAAGAGAGCGCGACCTGCAGCGCCATAGAGCCCTGCACATGGACTCGCTGTTCGCCTGCAAGATTTGTAATCAGGGATTCAACCGGCGGGAGCAATTGCAGCGCCATGAGCTGGAGGCCCATGGACCCAGCTATACCTGCAGTATTTGCTGCATCAACTTTCTGTATCAGGTGGAGCTGGAGAACCATCTAAAGGTCCATCAACTGCAGCACAAAATGGCGCAGAGTGCCCAAGAAGCCATCAATGCCGCCGCTAGTCTGCCCCTCAAAACGGTTGATCAAACGCCAGTGGCAGTAATGCCTCCGGTAATTCAGCCCTCGCCGGCTGAACTCTCCTTCTACAGCAACATGATTCCAACCATGAATCTGGGTTTTTACAGCGAGACTCGTCCGGAGGAGTAG
Protein Sequence: MVVNTCRLCHREVEADSPNIFESSMEFCKELSIAEISQHLWAVHYERHELLPELVCPECLELLLDAFEQRRGMQEREQGLQEQLKEMMRTDPKYRPGFNGNPGEFEPDEDCQIVDVDPEKLSETSEEEFLPCSEGDYENYEEDDEEEEEDFDEEDEEEGQNGDDVDMPLGMDAAQMALMEAGMKANNINSNPNSGLIKPKRAFLCEYCDLGFTLPSDCQQHEKTAHDPAAPYCCTFCNLRMTTRTALISHIKSLHDPDRPYVCTQCRKGFVRRSDLKKHTIVHTGVRPYTCNVCSKSFSRNTNLNKHIRIHSGVKPFVCQQCPRSFQTAVELMKHTRSHSELKAYQCGRCPYSFSRKDKLLAHQQIHTKHDIEQQQLGLLPPADGDLAQLHQQQQLQLQFQAKPKAAPQSKSSRNFRCDVCDRTFQRERDLQRHRALHMDSLFACKICNQGFNRREQLQRHELEAHGPSYTCSICCINFLYQVELENHLKVHQLQHKMAQSAQEAINAAASLPLKTVDQTPVAVMPPVIQPSPAELSFYSNMIPTMNLGFYSETRPEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00492409;
90% Identity: iTF_00492409;
80% Identity: -