Basic Information

Insect: Drosophila birchii
Gene Symbol: -
Assembly: GCA_008042755.1
Location: VNKA01001553.1:161120-164676[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00094 0.076 13.6 1.8 1 23 298 320 298 320 0.99

2 8 2e-06 0.00016 22.0 0.8 1 23 325 347 325 347 0.98

3 8 9.7e-08 7.9e-06 26.1 0.2 2 23 356 377 356 377 0.97

4 8 5.8e-07 4.7e-05 23.7 0.3 1 23 383 405 383 405 0.98

5 8 4.7e-08 3.8e-06 27.1 4.8 1 23 411 433 411 433 0.98

6 8 2.7e-07 2.2e-05 24.7 1.9 1 23 439 461 439 461 0.98

7 8 5.8e-06 0.00047 20.5 5.1 1 23 467 489 467 489 0.98

8 8 0.00019 0.016 15.7 0.5 1 21 495 517 495 518 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00094	0.076	13.6	1.8	1	23	298	320	298	320	0.99
2	8	2e-06	0.00016	22.0	0.8	1	23	325	347	325	347	0.98
3	8	9.7e-08	7.9e-06	26.1	0.2	2	23	356	377	356	377	0.97
4	8	5.8e-07	4.7e-05	23.7	0.3	1	23	383	405	383	405	0.98
5	8	4.7e-08	3.8e-06	27.1	4.8	1	23	411	433	411	433	0.98
6	8	2.7e-07	2.2e-05	24.7	1.9	1	23	439	461	439	461	0.98
7	8	5.8e-06	0.00047	20.5	5.1	1	23	467	489	467	489	0.98
8	8	0.00019	0.016	15.7	0.5	1	21	495	517	495	518	0.94

Sequence Information

Coding Sequence: ATGGGTTTTAAGCACGCCATGCTGCAGCGCAGTTACGAGCTGTCGCCCTCCCCGGCGCGCACACCACCCATGGCAGCCAATGCCACCACCAGAACCACCCACGAGGCGGCTCCTCCGGCGGCAGCTGTGCCCCCCGTTCAAGTCACCGACTTTAGCATCAGCCGGATATTGGGCAAGGAGCGAAAAAGTGTCCAAGACGCAAGCACCAATATCCTCGATCTCTCcaagagcagcagccacatcagCAGCAGAGGTAGCGAGCTAAGGACATCTCAACCAGGAGGATTACTCCCAGCAGGACCTTTGCTGTCGTCACCCTATGGATGCTACTCAATGCTGCCTCCGGATTTGGTGGCCATGGCCAATGCCACCCAGTTTTATGCCAAGTTCTTTCCACACCTGTTGCCCGCCTatgcggcggcagctgcagctgcaggactCAGCACTCCGCCCACTTCGCCATATCAGCAACCTCTcccgcagcagcatcagccccAGCTTCAGGCTCAGCAGAAGCGCTACTTTGCTCCCTATGTAATTaatggccaacagcagcaacagatcCGTACCAAAGGTCCTGCCTGCACCCGTCTGGACTGCCAGGAGTGCCTGGACTACTACCAACGACTGCAGGCTGGCTACAAGCAATCAACGCCTCTCATATCGCCGGCTTCCTCATCCGTGAGCAGTTCCAGCGGGATATTGCGACCAGCAAGGGAACTGCCAATGACAGCCGCCGGAGGATCCATCACCAGCAACATTTCCCTCAGCTCTGTTACCAATCTGAATCTGAGTTTGAACATGGCTCAGACGGCAACTGTGTCCACTGTCGTCGGCAGCAGCGCAGGAGCAATCGGGGGCTACAACACCGCTGCAGCAGAGGAGATTAGCTACAAGTGCAGGATATGCGAAAAGGTCTTTGGCTGCTCTGAAACTTTGCAGGCCCACGAGAAGACACACAAATCGCCGCGTTACGAATGCTCAGACTGCGGTAAAGGCTTCTCCCAGTTGCGGAACTACAAGTACCACCTGTCCGTCCATCGGGGCACCAAGGAGTTTGCTGCCGAGTGTCCAGAATGTGGCAAGACCTTCAACGACAAAGGCTACTTGAGTAGCCACATGAAGATCCACCGGAACCGCAAGGAGTACGAGTGCCCCTACTGCCCCAAGTCCTTTAACCAACGGGTGGCCTTCAACATGCACGTCCGGATCCACACGGGCGTAAAGCCGCACAAGTGCTCCGAGTGCGGAAAGAGGTTTTCCCGGAAGATGCTCCTCAAGCAGCACATGCGCACCCACAGCGGCGAGAAACCCTACCAGTGCTCCGTGTGTGGAAAATCCTTCGCCGACCGCAGCAACATGACGCTGCACCATCGCCTGCACTCCGGAATCAAGCCCTTTAGCTGTCCCCTGTGCCCGAAAGCCTTCACCAAGAAGCATCACCTTAAAACGCACCTCAACTATCACACTGGCTGCAAGCCCTACGTCTGCCCGCATCCCAACTGCAACCAGGCCTTCACACAGTCCAGCAACATGCGTACCCATGCCAAGAAGTGTCAGTATCGTCCGCTGGAAGGAGCAGCCACTGCATCCCTTcctgcggcagcggcggcgaagTCTTCCCAACAACTGCAGATGCCAGTGCCGACCACTTTGGCCGTTGCCATGGCAACGTCTCCGGCGTTTGCGATGCCAATGCCACCACCACCTggaccaccgccgccggctcAGCAGACCCTGCTCAGCAATCTGAGGACATTTTAA
Protein Sequence: MGFKHAMLQRSYELSPSPARTPPMAANATTRTTHEAAPPAAAVPPVQVTDFSISRILGKERKSVQDASTNILDLSKSSSHISSRGSELRTSQPGGLLPAGPLLSSPYGCYSMLPPDLVAMANATQFYAKFFPHLLPAYAAAAAAAGLSTPPTSPYQQPLPQQHQPQLQAQQKRYFAPYVINGQQQQQIRTKGPACTRLDCQECLDYYQRLQAGYKQSTPLISPASSSVSSSSGILRPARELPMTAAGGSITSNISLSSVTNLNLSLNMAQTATVSTVVGSSAGAIGGYNTAAAEEISYKCRICEKVFGCSETLQAHEKTHKSPRYECSDCGKGFSQLRNYKYHLSVHRGTKEFAAECPECGKTFNDKGYLSSHMKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCSECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRTHAKKCQYRPLEGAATASLPAAAAAKSSQQLQMPVPTTLAVAMATSPAFAMPMPPPPGPPPPAQQTLLSNLRTF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00531796;
90% Identity: iTF_00526008;
80% Identity: -