Basic Information

Insect: Drosophila bipectinata
Gene Symbol: gfi1b
Assembly: GCA_018153845.1
Location: JAECYF010000002.1:10631097-10632982[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0026 0.2 12.1 2.0 2 23 398 420 397 420 0.95

2 6 0.00018 0.014 15.7 1.0 1 23 427 450 427 450 0.95

3 6 1.7e-05 0.0013 18.9 0.5 2 23 456 477 455 477 0.96

4 6 0.00016 0.012 15.9 1.0 1 23 483 506 483 506 0.91

5 6 3.4e-05 0.0026 18.0 4.7 1 23 512 534 512 534 0.95

6 6 7.6e-06 0.00057 20.0 1.7 2 23 541 562 540 562 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0026	0.2	12.1	2.0	2	23	398	420	397	420	0.95
2	6	0.00018	0.014	15.7	1.0	1	23	427	450	427	450	0.95
3	6	1.7e-05	0.0013	18.9	0.5	2	23	456	477	455	477	0.96
4	6	0.00016	0.012	15.9	1.0	1	23	483	506	483	506	0.91
5	6	3.4e-05	0.0026	18.0	4.7	1	23	512	534	512	534	0.95
6	6	7.6e-06	0.00057	20.0	1.7	2	23	541	562	540	562	0.97

Sequence Information

Coding Sequence: ATGGAAGTTTGCGGCAGCGTGCTGGTGAATACGAATTACCAGCAGTTCCGGCTGAAGTGCATTTACTGCCCGACAGAGAGCGAACTTCATGATTGGAAGCTGTTCATAAACCATGTGCGGACATCACATTATTCCGAGGAGGACGAAGCCTCTGCCAATGCCCCAATCAAAGAAACCACAGATTCATTAGATCCTGAAATCGAATACGATGGAAATGATTTTTATGATATCATTGAAACGGTTGAGGAAGAGGACCAATGGCTAAAATCTGAAAACATGGAAGAGGATGACGGTGAATACCTTCCTGAATCCAATGAAGTGTCAGCTACATCAGAAGGTGATGCAGTCAGCTCCCACAATGACTTGGCTGATGTAAAGCCAGAAGGTTCTACGAGGTATGATAGTGGTAGCGAATATGATTCCTATGAGGAAGGAGCACCGCAACGACGGCGTCCAGGACGCCCACCAATACGTACCAGACCGGATCAAGTTTTCAAATTCAAAGTGTCGTTTATACGAAGCAATCCCCGTGTGCTGCATTTGATCCAGGTGTATAGGGAACACCCTTGTCTATGGAATCCATCAGATGATTTTTATGAAGATGAGAACGTGCGGAAACAGGCGTACCAATCGATAATAAGTCGTATGGAACTAAAAACTGACGTCCTTTTGACTGTGGCCGAGCTAAAACGCACTCTTGTGCAGCTGCACACGCAATATGCCCTTGCAGGAGAAATGAAAGCAAAGGGTAAGCTGGTCGGACTCGCATCACGTTACTATGCCAAATGCGAATTCCTCAGCGTGTCGCCTCCCGTAAAAGTAAGGCGAATTGAAGAGGACAGTAACATTATTACAATTAAGCTCGATTTTAAGGAGGATAATTTAGTGACTAGCTCTTTTATTGAGACGTATGCCAACTACCCGATGCTATACAATCCTTCACATCCCGATTTCTCTTCGATAGATATACGAGCCGACGCCTATGTTAAGTTTGCGGAGGAGTTCCAGCCTGTCGTGAAGGCGAATGAAACGGACGTCTACATAGCCGTGAATAAGCTAAGGCGTTGGGCTTATGAGGCTATGAGACGTCTCAAAGCCAAAGAGCTCATTGAGTCTTGCAATAAGCAAGAGGTGCAGTACTTGCGTATGTGTAGTTTCTTACCCGCTAAAGGATCGGAAAGTGCTGTATTATATTGCGATACCTGCAACAGGCGATTTCATGGCGATTACAACCTGCGCGTGCATATGTTTAAAGCGCACATGTTGGGCGATCTACCTTATCTGTGTTCTATGTGCCCAAGGCGCTTTGACAGGCAAGTGGACATGGAACGACACAAACAACGCTCCCATTTCGATAAAGGGTTGAAGTGCGAATATTGCGAAAAAACCTTTGCTGTTGCCCATGATTTAAAAGTGCACACCCTTATCCATACCGGCGAGAGGCCGCATGTGTGCGAAGTTTGTGGAAAATCGTTCCGTCTGAAACTGCTTTTGGATCATCACATAAACGGCGTTCACCTAAACATTCGGCCCCATGCCTGCCACTTGTGTGATAAAAGTTTCCGCAAAAAGTTCGAGTTGTCCAACCACATTAAAGGACATTATAATATTCGTGATAAAAAATGCGAGATATGTGGAGCTTCTTTTTACGACCATTCTTCCCTGTCCAGACATCGTCGAGGGCATAGAGAAAAACAATAA
Protein Sequence: MEVCGSVLVNTNYQQFRLKCIYCPTESELHDWKLFINHVRTSHYSEEDEASANAPIKETTDSLDPEIEYDGNDFYDIIETVEEEDQWLKSENMEEDDGEYLPESNEVSATSEGDAVSSHNDLADVKPEGSTRYDSGSEYDSYEEGAPQRRRPGRPPIRTRPDQVFKFKVSFIRSNPRVLHLIQVYREHPCLWNPSDDFYEDENVRKQAYQSIISRMELKTDVLLTVAELKRTLVQLHTQYALAGEMKAKGKLVGLASRYYAKCEFLSVSPPVKVRRIEEDSNIITIKLDFKEDNLVTSSFIETYANYPMLYNPSHPDFSSIDIRADAYVKFAEEFQPVVKANETDVYIAVNKLRRWAYEAMRRLKAKELIESCNKQEVQYLRMCSFLPAKGSESAVLYCDTCNRRFHGDYNLRVHMFKAHMLGDLPYLCSMCPRRFDRQVDMERHKQRSHFDKGLKCEYCEKTFAVAHDLKVHTLIHTGERPHVCEVCGKSFRLKLLLDHHINGVHLNIRPHACHLCDKSFRKKFELSNHIKGHYNIRDKKCEICGASFYDHSSLSRHRRGHREKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00476178;
90% Identity: iTF_00566335; iTF_00580209; iTF_00539196;
80% Identity: -