Basic Information

Insect: Drosophila bipectinata
Gene Symbol: prg
Assembly: GCA_018153845.1
Location: JAECYF010000098.1:4826985-4828753[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.061 4.6 7.8 0.6 1 23 211 234 211 234 0.93

2 9 0.002 0.15 12.4 0.5 1 23 240 263 240 263 0.98

3 9 4.3e-06 0.00032 20.8 0.5 1 23 269 291 269 291 0.98

4 9 2.5e-08 1.9e-06 27.9 2.0 1 23 297 319 297 319 0.99

5 9 0.00013 0.0097 16.2 0.6 1 23 325 347 325 347 0.98

6 9 4.7e-06 0.00035 20.7 1.3 1 23 353 375 353 375 0.98

7 9 7.7e-06 0.00058 20.0 0.6 1 23 423 445 423 445 0.96

8 9 2.3e-05 0.0017 18.5 0.3 1 23 450 473 450 473 0.91

9 9 0.046 3.5 8.1 2.5 1 23 477 499 477 499 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.061	4.6	7.8	0.6	1	23	211	234	211	234	0.93
2	9	0.002	0.15	12.4	0.5	1	23	240	263	240	263	0.98
3	9	4.3e-06	0.00032	20.8	0.5	1	23	269	291	269	291	0.98
4	9	2.5e-08	1.9e-06	27.9	2.0	1	23	297	319	297	319	0.99
5	9	0.00013	0.0097	16.2	0.6	1	23	325	347	325	347	0.98
6	9	4.7e-06	0.00035	20.7	1.3	1	23	353	375	353	375	0.98
7	9	7.7e-06	0.00058	20.0	0.6	1	23	423	445	423	445	0.96
8	9	2.3e-05	0.0017	18.5	0.3	1	23	450	473	450	473	0.91
9	9	0.046	3.5	8.1	2.5	1	23	477	499	477	499	0.98

Sequence Information

Coding Sequence: ATGTTTATTCCGGAGCCCGAAGACTTCCTGCCGCCGACCTCGAGCTCGTGTCGTCTGTGCCACCGCGAAGCAAGCGTTGAATCGCCAAACATATTCGACAGCTCTCCGGAGTTCTGCAAGGACCTCAGCATTGCCGACGTTTGCCAGCGCCTTTGGGATGTCCAGTATGAACGGCACGAGTTTTTGTCGGAGCACATTTGTCCAAATTGTGTTGAAATACTGGAGGATGCTCACGAGCAGCGTCGCGGGATGCAGGAGCGAGAACAGGCCCTACAGCAGCAACTAATTGGTCTCCTTAAAAAAGACGCCATGTATCGTCCAGGCTTGAATGGAAATCCAGGCGTCTTCGAAGCTGAAGAAGACCGAACTATTGTTGATGTGGATCCTGAAAAGCTGTCAGAGACCAGCGAAGACGAGTTCCTCGGCTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGGGTATGGATGCGGCACAAATGGCTTTGTTAGAGGCCGAAATGAAGACAGCTGGAGCCAATGACGACGCCAACCCAGGTGCGCCACGACCTAAGCGGGCTTTTCTGTGCCAGTATTGCGATGTGGGATTCACTCTCCCGTCAGAATGCCAGCAACACGAACTCACCGCCCACGACCCCAATGCACCATATTCTTGCGCCTTCTGCAACCTGTGTCTGGTCACGCGGCCCGCTCTGATCTCGCACATCAAGACGTTGCACGATCCTGATCGACCTTATGTGTGTGCTCAATGCCGCAAAGGATTTGTCCGGCGCTCCGATCTAAAGAAGCACACGATTGTACATACAGGCGTGCGCCCTTACACCTGCAACGTGTGTTCCAAGAGTTTTTCGCGAAATACTAACTTGACTAAGCACGTCCGCATCCATAGTGGGGTGAAGCCGTTCGTCTGCCAGCAGTGTCCGCGTTCCTTCCAAACGGCAGTCGAAATGATGAAGCACTCCCGCTCGCACTCCGAAGTGAAACCTTTCCAATGTGGCCGTTGTTCGTACTCGTTCTCCCGGAAGGATAAGTTGCTGGCTCACCAACAAGTCCACACACGACGGGATGTGGAACAGCAGCAGGCGCAAATGGGAGGGCTTCCACCGATGGAGGGCGATTTGGCTCAGTACCAATTCCATCAGCAACAGGTCCAAGTCAAGCCAAAACCATCATTGCAGCCCAAATCTTCTCGAAATTTCCGATGCGACGTCTGTGACCGGGTGTTCCAGCGGGAGCGGGACTTGCAACGGCATAGGGCCCTCCATATGGACTCACTGTTTGCCTGCAAGATCTGCAATATGGGATTCAATCGTCGAGAGCAGCTGCAGCGTCACGAATTGGAAGCCCATGGGCCCAGCTACACGTGTAGTATTTGCTGCATCAGTTTCCTACATCAGGTGGAATTGGAGAATCACTTAAAGGTGCATCAGCTGCAGCACAAAATGGCCCAGAGTGCCCAACAAGCCATTAATGCCGCCTCTGTCATACCGCACAAAGTAATGGATCAAGCTCCAGTGCCAATAATGGCCCCTGTAGTGCAGGAGCCGATGCCAATGCGACCCTCGGCAGCCGAACTCTCCTTCTATAGCAACATGATACCCACTATGAATTTGGGATTTTATAGCGAAACGAGACCCGAAGAATAA
Protein Sequence: MFIPEPEDFLPPTSSSCRLCHREASVESPNIFDSSPEFCKDLSIADVCQRLWDVQYERHEFLSEHICPNCVEILEDAHEQRRGMQEREQALQQQLIGLLKKDAMYRPGLNGNPGVFEAEEDRTIVDVDPEKLSETSEDEFLGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMDAAQMALLEAEMKTAGANDDANPGAPRPKRAFLCQYCDVGFTLPSECQQHELTAHDPNAPYSCAFCNLCLVTRPALISHIKTLHDPDRPYVCAQCRKGFVRRSDLKKHTIVHTGVRPYTCNVCSKSFSRNTNLTKHVRIHSGVKPFVCQQCPRSFQTAVEMMKHSRSHSEVKPFQCGRCSYSFSRKDKLLAHQQVHTRRDVEQQQAQMGGLPPMEGDLAQYQFHQQQVQVKPKPSLQPKSSRNFRCDVCDRVFQRERDLQRHRALHMDSLFACKICNMGFNRREQLQRHELEAHGPSYTCSICCISFLHQVELENHLKVHQLQHKMAQSAQQAINAASVIPHKVMDQAPVPIMAPVVQEPMPMRPSAAELSFYSNMIPTMNLGFYSETRPEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00550398;
90% Identity: iTF_00481690;
80% Identity: -