Basic Information

Insect: Drosophila bifasciata
Gene Symbol: ZNF574
Assembly: GCA_009664405.1
Location: CM019043.1:6577060-6579276[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.66 44 4.6 1.0 2 23 332 354 331 354 0.94

2 10 0.033 2.2 8.6 0.1 6 23 364 381 364 381 0.99

3 10 6.4e-05 0.0043 17.2 0.5 1 23 387 409 387 409 0.97

4 10 0.00023 0.015 15.4 0.7 1 20 424 443 424 447 0.87

5 10 9.2e-05 0.0061 16.7 0.9 1 23 455 478 455 478 0.97

6 10 0.00032 0.021 15.0 2.0 2 23 485 507 484 507 0.92

7 10 0.0011 0.07 13.3 0.4 2 23 519 541 518 541 0.97

8 10 0.00054 0.036 14.3 7.1 1 23 548 571 548 571 0.93

9 10 2.4e-06 0.00016 21.7 0.8 1 23 577 599 577 599 0.98

10 10 6.7e-05 0.0044 17.1 1.3 1 23 605 628 605 628 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.66	44	4.6	1.0	2	23	332	354	331	354	0.94
2	10	0.033	2.2	8.6	0.1	6	23	364	381	364	381	0.99
3	10	6.4e-05	0.0043	17.2	0.5	1	23	387	409	387	409	0.97
4	10	0.00023	0.015	15.4	0.7	1	20	424	443	424	447	0.87
5	10	9.2e-05	0.0061	16.7	0.9	1	23	455	478	455	478	0.97
6	10	0.00032	0.021	15.0	2.0	2	23	485	507	484	507	0.92
7	10	0.0011	0.07	13.3	0.4	2	23	519	541	518	541	0.97
8	10	0.00054	0.036	14.3	7.1	1	23	548	571	548	571	0.93
9	10	2.4e-06	0.00016	21.7	0.8	1	23	577	599	577	599	0.98
10	10	6.7e-05	0.0044	17.1	1.3	1	23	605	628	605	628	0.97

Sequence Information

Coding Sequence: ATGACAGCCTGTGTTCTTTGTTTGGGTTTCTCCGATGCTTCCTACGGCCTGCAGTCCGATGAAGGGATGCGGCTCAACATAAGGGAGActataagcaaacatttccTGTTCTTTGAGCTACCCATTGCGGATAATAATTCGGAGGTGATCTGCCGGGAGTGCTGGCAGAACGTGATTAGTTTCAATGAGTTCCATCAGAGGGTGTACGTCCTgcaccagcagcggcagagcgaCTCGAAAAGTGTTCCAATCGAGTTCTGTGGCGAGACAGAGGCCATCAATCCGCTATTTTCGGCTGAACTCGATGCCCTGTCCGAGGGTTTCTTTGCCCCCAACGCGGTTAAGGTGGAGGTGAACGAATTAGAGCCGCTGACCAAGGTGGAGCTACTGGAGGATCCGGTGGACACTGAACCCAAAACTGCTACGAAAAGGACCAGTGGAAACTCGGATTGGCCCACCAATCCGAAGCGGCGCATTAAGAATGAACAGCCACTTGGTAGTGATTCAGATGGAGACGTGCCGCTGGCGGAGTTCCTAAACACAGATGCAAGGAATGATTCGAATGGATCGTCCGAACGAAACGGAACCGGCAAGGGCCGTCAGCTGAGAAGAAGTACGCGGCGTGGCCGGAAACCAATGCCCAAACTCGAGTCTCCTGATCGACTGAAAAAGGAATTGGACTCAGATGACGATAACGATAATGATAATGACAATGGGTTTGTGGCCGCCGAGGCTGTCCTGGGAACGGAAGACAGcgccagctcctcctccagtGACAGCAGCGATGGGGACTCGGACAACAGTTTGCCGGACTTTGAGCCGGAAGAGCGATACGCTGAGATACCCAAGCGGGTCGTAGTCAAGCCCAAAAAGTACCGAAAGCGTCCGAAGCCTTTGGTTCCACCCGTCCGCATGAGTCGCGAGGAGATCGAACGGCGCAAGCTCCAGCAAAACGAGTATGATGAAATTATCATCAAGTTCTTCAAAAAGCTGTCCTGCGAAATATGCAATCTCCTGGTGCAGAATTTTGCCGACATGCGACGCCATCACCGCCTCACGCACAACATCGAGTCGGGCTACGTCAGCTGCTGCGGAAAGAAGTTCACGATACGCAAAACCTTGGCTGAACATGTGATGGTTCACCAGAATCCAGACCACTTTATGTGCACCCAATGCGGGAAAGTGTTTCAGGACTCCCGCAGCATGGAGGTACACGAGCAATCGCACACGACTCCGCCCGACCAGACGGATCCCAAGGAGAAGCGGGTTTATCAGTGCGAAAAGTGCCCGAAAACGTTCACCACCAAGGCGGCTATCGAGTATCACAATGTGTCCAAGCATGTGGCCAAGTCCGACTACAAATACAGCTGTCCAGAGTGCAAAAAGAAAATTCCCACAGAGCGCAAACTGAAGGAGCACATGCGCTATATGCATGACCCAGAGACGGCCATCATGTGCGATAAGTGCGGCAAGACAATGCGCTCCCAAACGAATCTCAAAAAGCATCATGAGCTGGAACATTCCGACGAGCCCCGTCCCAAGCCCGAGCCCGTGCAGTGCGAGATTTGCGGCACTTGGCTGCGCCATCTGTCCGGCCTGAAGCAGCACATGAATACGGTGCACGAGCCGCCGGGTGGTGAGCATCGCTGCCACATCTGCAACAAGACTTCAACAAACTCCAGAGCCCTCAAGCGACATATTTACCACAATCATCTCTGCGAGCGAAAGTTCAAGTGCGGAATGTGTGAAAAGGCTTTTAAGCGACCCCAAGATTTGCGAGAACACACTTCCACGCACACCGGAGAGGTGCTCTACACCTGTCCCAACTGTCCAATGACGTTCTTTTCGAATGCCAACATGTACAAACATCGCCAGCGCCTGCATCGCGCCGAATGGGAGGCAGACCGCAAGAAGCCGCTGCCGCCCAACATAATGAAAATCTCGCAGGGTGCCTCCACAGCCATGAAGAAGCGCCAGATCAGCACGTCCATGTTCCCACAGTCGGAACCAGCGCCAGCTGGCCCCTAG
Protein Sequence: MTACVLCLGFSDASYGLQSDEGMRLNIRETISKHFLFFELPIADNNSEVICRECWQNVISFNEFHQRVYVLHQQRQSDSKSVPIEFCGETEAINPLFSAELDALSEGFFAPNAVKVEVNELEPLTKVELLEDPVDTEPKTATKRTSGNSDWPTNPKRRIKNEQPLGSDSDGDVPLAEFLNTDARNDSNGSSERNGTGKGRQLRRSTRRGRKPMPKLESPDRLKKELDSDDDNDNDNDNGFVAAEAVLGTEDSASSSSSDSSDGDSDNSLPDFEPEERYAEIPKRVVVKPKKYRKRPKPLVPPVRMSREEIERRKLQQNEYDEIIIKFFKKLSCEICNLLVQNFADMRRHHRLTHNIESGYVSCCGKKFTIRKTLAEHVMVHQNPDHFMCTQCGKVFQDSRSMEVHEQSHTTPPDQTDPKEKRVYQCEKCPKTFTTKAAIEYHNVSKHVAKSDYKYSCPECKKKIPTERKLKEHMRYMHDPETAIMCDKCGKTMRSQTNLKKHHELEHSDEPRPKPEPVQCEICGTWLRHLSGLKQHMNTVHEPPGGEHRCHICNKTSTNSRALKRHIYHNHLCERKFKCGMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKISQGASTAMKKRQISTSMFPQSEPAPAGP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00471813;
90% Identity: iTF_00601230;
80% Identity: -