Basic Information

Insect: Drosophila bifasciata
Gene Symbol: zfh1
Assembly: GCA_009664405.1
Location: CM019044.1:39927123-39929056[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.13 8.6 6.8 0.2 1 21 290 310 290 311 0.95

2 10 1.9e-06 0.00013 22.0 0.1 1 23 319 341 319 341 0.98

3 10 0.0064 0.43 10.9 0.6 1 23 344 367 344 367 0.93

4 10 1e-06 6.9e-05 22.8 1.0 2 23 374 395 373 395 0.98

5 10 2.7e-08 1.8e-06 27.8 1.0 1 23 401 423 401 423 0.98

6 10 1.3e-06 8.8e-05 22.5 0.9 1 23 429 451 429 451 0.99

7 10 0.011 0.76 10.1 3.9 1 23 457 479 457 479 0.98

8 10 0.00083 0.055 13.7 0.3 1 23 485 507 485 507 0.98

9 10 0.00019 0.012 15.7 2.8 1 23 513 535 513 535 0.99

10 10 0.00087 0.058 13.6 0.1 1 23 541 563 541 563 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.13	8.6	6.8	0.2	1	21	290	310	290	311	0.95
2	10	1.9e-06	0.00013	22.0	0.1	1	23	319	341	319	341	0.98
3	10	0.0064	0.43	10.9	0.6	1	23	344	367	344	367	0.93
4	10	1e-06	6.9e-05	22.8	1.0	2	23	374	395	373	395	0.98
5	10	2.7e-08	1.8e-06	27.8	1.0	1	23	401	423	401	423	0.98
6	10	1.3e-06	8.8e-05	22.5	0.9	1	23	429	451	429	451	0.99
7	10	0.011	0.76	10.1	3.9	1	23	457	479	457	479	0.98
8	10	0.00083	0.055	13.7	0.3	1	23	485	507	485	507	0.98
9	10	0.00019	0.012	15.7	2.8	1	23	513	535	513	535	0.99
10	10	0.00087	0.058	13.6	0.1	1	23	541	563	541	563	0.98

Sequence Information

Coding Sequence: ATGGATGTGCAGAAGATTTGCTTGACCTGTTTGAGTTTAACAGGTCCATTCCTATCCATTTATGATGGCGGATCAGGCAGCTGCCTGGCGGATATGCTCAAACAGTTCACCAAAACGAAGCCGCGACCCGAGGATAATCTGCCCAAACAGGTCTGCCTGGGCTGTCTGAGCGAGATAAACCACTGCTACACCTTCAAGATCAAGTGCGAGAACTCCAGTCGTACTCTTCGCCAGCTGCTGCCAAATGCCCTGCCGGAGGAGCCCGAGTTCGCCGCCAAGCCAGCGGTGCCCACAGAAGAGAAGTCAGTACAGACCACCGAGCCCTGTGCCCCTACAACAGCCACAGCGGAAGTGCAAACCACTGAAACACACACCACAGATGCCGCGCAGAATACCAGTCTGGATAAGTCGGTgcccgaggaggaggatgcgGACGAAGACGGTGAGGATGGTTGTCAGGTGTTCGACTACGAGCTGACCGTGGAAAAGGAGGAAAATGAAAAGGATATTACCATCTATAAAGACGAGCCCGAGAGCCAGAAGACAACAGAATGTAATATATCCATATTCGAGGCTGCCGACAGCGACACGGAGACACCCGCACCCCCACCAACGCCCAAATCGCAAATGAGAACGCGCAAGAGTGCCGCcaagctgttgctgcagcagcaggaggtgaAGCAGTCACCCAAGCAGGAAATGGAAGACTCCACGACACCCGaaccagaggcagagccagcacCGGCCAAGAGATCCTCACGACGCCGTCCAGCCGAGAAaccagcagaaacagcagaaaTGGTGCTGGCTCCTGTGCCGAAGCTGATCAAAGTCAGCATCACCCAGGGCGAAATAATGGATCTCAAGTATCATTGTGATCGCTGCAATGCTGGCTTTGCCCTGGAGAAATCCCTGGTCATACATCGCCGGCAGAAGGGCTGCATCAATCGCAATTATCCCTGCAACGAATGCGAGCGGGTGTTTGTCTCGCCGGAGCATTTGGCGGAGCATCAGGCCACACATGGCACCTACAATTGCCAGGAGTGTGGGCTGCTGTGCGACTCCAAGGAGCAGCTGGGCAAGCATATGGTGCAGGGCCACAAGAGGAATCTGCGCAATCAGTGCAACGTTTGTAAGAAGGTTTTTACTATGCTCTCTACCCTGCGGGATCACATGCGCATCCATACCGGGGAGAAGCCATTCGTGTGCAACATTTGTGGCAAGAGTTTTACACAAAATGCGAATCTGCGCCAGCACAAGCTCCGCCACTCGGACATCAAGAGCTTCAAGTGCGGCGAGTGTCCGCATTCGTTTGTGACCAAAGCAGAGCTGACCTCCCACGCGCGCACCCACACCGGCGTCAAGCCGTACGAGTGTGAGGTGTGCATGTCCAAGTTCACGACGAGCTGCTCCCTGGCCAAGCACAAGCGGAAGCACACGGGGGAGCGTCCGTATGCCTGCGATCTGTGTCCCATGCGCTTCACGGCGCTGAATGTGCTCAAGAATCATCGGCGCACGCACACGGGCGAGCGTCCCTACGTGTGCCCCTTCTGCGCAAAGACCTTTACACAGCGCGGCGACTGCCAGATGCATCAGCGTACGCATCAGGGCGACAAGATCTACACTTGTCCGGTGTGCAGCGAGGAGTTCAAATCAATGCCAGAGATGCGCACACACGTAGCCATGCACGAGCAGGAGGACAAGCGTTTGATGCACTTTACGCTGCTCAGCAACAAGGAGAATGGCAGCAGTGGGGCAGCACTGGACGATGAGCTCACCGAGGTCACAGATTCAGCATTGATGGGCATATAA
Protein Sequence: MDVQKICLTCLSLTGPFLSIYDGGSGSCLADMLKQFTKTKPRPEDNLPKQVCLGCLSEINHCYTFKIKCENSSRTLRQLLPNALPEEPEFAAKPAVPTEEKSVQTTEPCAPTTATAEVQTTETHTTDAAQNTSLDKSVPEEEDADEDGEDGCQVFDYELTVEKEENEKDITIYKDEPESQKTTECNISIFEAADSDTETPAPPPTPKSQMRTRKSAAKLLLQQQEVKQSPKQEMEDSTTPEPEAEPAPAKRSSRRRPAEKPAETAEMVLAPVPKLIKVSITQGEIMDLKYHCDRCNAGFALEKSLVIHRRQKGCINRNYPCNECERVFVSPEHLAEHQATHGTYNCQECGLLCDSKEQLGKHMVQGHKRNLRNQCNVCKKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSDIKSFKCGECPHSFVTKAELTSHARTHTGVKPYECEVCMSKFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCAKTFTQRGDCQMHQRTHQGDKIYTCPVCSEEFKSMPEMRTHVAMHEQEDKRLMHFTLLSNKENGSSGAALDDELTEVTDSALMGI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00484572;
90% Identity: iTF_00603507;
80% Identity: -