Basic Information

Insect: Drosophila biarmipes
Gene Symbol: Znf574
Assembly: GCA_018148935.1
Location: JAECYG010000260.1:8964050-8966872[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 4.7 2.8e+02 2.0 2.0 2 23 330 352 329 352 0.92

2 10 0.056 3.3 8.1 0.1 6 23 362 379 362 379 0.98

3 10 5.2e-06 0.00031 20.8 3.1 1 23 385 407 385 407 0.98

4 10 0.81 48 4.5 0.8 1 14 416 429 416 439 0.73

5 10 0.00047 0.028 14.6 2.8 1 23 447 470 447 470 0.97

6 10 0.15 8.9 6.8 0.4 3 23 478 499 476 499 0.92

7 10 0.47 28 5.2 0.2 2 23 511 533 510 533 0.93

8 10 0.0038 0.23 11.8 3.2 1 23 540 563 540 563 0.93

9 10 1.7e-06 0.0001 22.3 1.4 1 23 569 591 569 591 0.98

10 10 0.038 2.3 8.6 3.3 1 23 597 620 597 620 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	4.7	2.8e+02	2.0	2.0	2	23	330	352	329	352	0.92
2	10	0.056	3.3	8.1	0.1	6	23	362	379	362	379	0.98
3	10	5.2e-06	0.00031	20.8	3.1	1	23	385	407	385	407	0.98
4	10	0.81	48	4.5	0.8	1	14	416	429	416	439	0.73
5	10	0.00047	0.028	14.6	2.8	1	23	447	470	447	470	0.97
6	10	0.15	8.9	6.8	0.4	3	23	478	499	476	499	0.92
7	10	0.47	28	5.2	0.2	2	23	511	533	510	533	0.93
8	10	0.0038	0.23	11.8	3.2	1	23	540	563	540	563	0.93
9	10	1.7e-06	0.0001	22.3	1.4	1	23	569	591	569	591	0.98
10	10	0.038	2.3	8.6	3.3	1	23	597	620	597	620	0.97

Sequence Information

Coding Sequence: ATGGATTCCTCTTCGTGCTGCTTACTCTGCATGTGCGAGTATCCGGCCATGATGGGGGACTACATCGACGTGCAGTCCGCGCGGGCGGTCCAACTGGAGGTGGCCAGGATCGTCAACCAGCACTTTCCCTTCCAGATCAGCAAGGAGAGCCACGACAGGATTTGCGGGCGCTGCTGGAAAACCGTCTCCGACTTTCACACATTGCACGAGTTCGTGAGTGCAGCGCAGCATTCCTTGCAGGAGACCAAAGTGCTGCTCATGGAGGATGACCCCCTCACACAAGCTACTTCCTCCTTTCCGGAAACTCTGAAGCTGCCAACTCTGGAGGAGGAGCGGTTGCAGGAGCCACCGGAACCCCTTGATGGGCGAAATTTCTTTTACCCGGAGGTCAAGATAGAAGAACACGAGCTGGACCACCTACCCCGCATCGAGATCCTGGAGAGCACCGCCAACACGCAAGAATCTCAGGATCCAGTGGAAGGTACAGCCAGGCGCTTAAGGAAGCGTCTTAAGGCAGAGGAAGGAGCTGCTGGGGACAAGGATAAGGATGAGGATGACGTAGAAGAAACTGCAGAGCCGGCGCCGCCCAAAAAGAGACGAGGTCGTCCCCGGAAAGCAGACACAGCAATCGCCCCTGCCCAGAAACCTACGGAAGACATCAAACTTGACCTTAAGGCAGAGGAGCTCGACGAGTTCTTGGAGGAGTCCACGGACCCCGATTTCTCAGGCCTGTTGCACAGCGACGACTCCTCCGAGGACAACTACGGAGGCAGTGATGCCTCCGACTCTGACTTCGAACTAGACAATCCCGAAAAGCAGGAGTTTGCCGTGCTGCCCAAGCGAACGGTGGTACGCCCCAAGAAGTACAAGAAGCGGACGAAACCGGCAGAGCCGAAGGTGCGCATGTCGCGCGAGCTGCTGGAGCAGCGCAAGAAACAGCAGGAGGAGTACGACGTCATCATCGCCAAGTTCTTCACCAACGTGCTGCCGTGTGCCATCTGCAATCTGCTGGTGCACAACTTCACCGAGATGCAGCGCCACCACCGACTGACCCACCAGGTGGATCCCGGCTACATGATGTGCTGCGGCCGCAAGTTCACGCAGCGCAAAGTGCTGGCCGAGCATGTGCTCGTCCATTGGAATCCTGACCACTTTAAGTGCAGCGTGTGCGAGAAGTCATTCCAGAATTCAAGGCACCTGGAGTCTCACCAGCAGGTGCACATGGATCCAGCCATCAAACTGACCTTCAGCTGCGACCTGTGCTCGAAGACCTTCCTCAGCAAGACGGCCATCGACTACCACAAGCTGAACAAGCATGTGCCCAAGTCGGAATTCAAGTTCACCTGTACCGAGTGCAATAAGAAATTCCTTACCGAGCGCAAGCTGAAGAACCACATGAGCTCCATGCACGACCCAGAGAGCACCATCATCTGCGACAAGTGCGGCAAGCAGATGCGCACCAAGATCATCCTAAAGAAGCACCAGGAGCTGATGCATTCGGACAAGCCGCGTCCGGAGCCGGAGCTGAAGCAGTGCCAGATTTGTGGCGCCTGGCTGAAGGGAATGACCGGTCTGAAGCAGCACATGAAGAGCATCCATGTGGAGAGTGCGGGAGAGCACCGTTGCCACATCTGCGCCAAGGTGTCTCCAAATGCCAGGGCTCTCCGGCGTCATATCTACCACAATCACGAGTGCGAGCGCAAGTTCAAGTGCACCATGTGCGAGAAGGCCTTCAAACGGCCGCAGGAGCTGAAGGAACACACATCCACCCACACCGGCGAGGTTCTTTACACCTGTCCGAATTGCCCGATGACATTCTTCTGCAGCGCCAACATGTACAAGCATCGCCAGCGATTGCACCGCGCCCAATACGAGGCGGACAAGAACCAGCCCAAGCCCCCCAATATCCTGAAGATATCGCGCAACGCCTCCTCGCAAAACAAGCCCAAACAGGAGATCTAG
Protein Sequence: MDSSSCCLLCMCEYPAMMGDYIDVQSARAVQLEVARIVNQHFPFQISKESHDRICGRCWKTVSDFHTLHEFVSAAQHSLQETKVLLMEDDPLTQATSSFPETLKLPTLEEERLQEPPEPLDGRNFFYPEVKIEEHELDHLPRIEILESTANTQESQDPVEGTARRLRKRLKAEEGAAGDKDKDEDDVEETAEPAPPKKRRGRPRKADTAIAPAQKPTEDIKLDLKAEELDEFLEESTDPDFSGLLHSDDSSEDNYGGSDASDSDFELDNPEKQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDVIIAKFFTNVLPCAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAIKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCTECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELKQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPKPPNILKISRNASSQNKPKQEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00494659;
90% Identity: iTF_00578837;
80% Identity: -