Basic Information

Insect: Drosophila biarmipes
Gene Symbol: PRDM1
Assembly: GCA_018148935.1
Location: JAECYG010000079.1:7825241-7846614[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.8e-05 0.0017 18.5 2.5 1 23 877 899 877 899 0.99

2 5 8.5e-06 0.00051 20.1 5.1 1 23 905 927 905 927 0.98

3 5 1.8e-06 0.00011 22.3 4.3 1 23 933 955 933 955 0.98

4 5 0.00059 0.035 14.3 2.4 1 23 961 983 961 983 0.97

5 5 0.0001 0.006 16.7 0.1 1 22 989 1010 989 1010 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.8e-05	0.0017	18.5	2.5	1	23	877	899	877	899	0.99
2	5	8.5e-06	0.00051	20.1	5.1	1	23	905	927	905	927	0.98
3	5	1.8e-06	0.00011	22.3	4.3	1	23	933	955	933	955	0.98
4	5	0.00059	0.035	14.3	2.4	1	23	961	983	961	983	0.97
5	5	0.0001	0.006	16.7	0.1	1	22	989	1010	989	1010	0.96

Sequence Information

Coding Sequence: ATGCATGGACATCACAACCACAACCATCTGCAGCAGCAGCAGCCACAGAATCCGCAGGATCAGCAGCCGGGAGCCATCATGAAGGCAGCCAACCATCCGCAGCCCCACCACCCACTCAGCCACCCACATCCGCACCAGCAGCACCCCCACGCCCAGCCACATCCGCATCCCCATCCACACCACAAGCTGTCGGCGAGAAGGGCGCGCAGTCGCAGTCGAAGTCGCAGTCCGTCGCCGGATGGCAACCAGGACTACGATGTGACCCGGATGCGGGAGGAGGACTTCCAGCGGCTGGCCGTCTACCTGGTGCCGGATGTCCAGGCGGAGCGGGGACTGCCCAACCGGGCGGACAAGACGCTGCCGCGCAGCCTGACGCTCAAGTCATCCATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGGGTCATCCCACGTGGCACTCGCTTCGGCCCATTCGAAGGCATTCCAACCTCAAACTATCCCAATGATAAGAATAAGGCTCGCTATTTCTGGCGGATCTTCAAGGACGACGACTACTATTATCTGGATGGCTCGGATCGCTCGCAGTCCAATTGGATGCGCTACGTGGCGTCCGCGTACAGTCTGTCCGTGATGAACCTGGTGGCGTGCCAGCACCAGGAGAACATCTACTTCTACACCACCCGCGACATTCTGCCCAACGAGGAGCTGATGGTGTGGTACTGCAAGGACTTCGCCAGTCGCCTGGGCTACGACGTGGATCCCGAGACGACGATCTTCGGCGCCTGCAAGCAGGCGGTGGAGGCGGAAGAGGAGGTCGACGAGGAGGAGGAGGAGGCGGAGGGCGAGGATGGCAAGCCGCGATACTCGATGCCTGCCCCGGAAATTCCCGCCGATGTGGCCGTGAGTCACATCACCTACGTCATGGGTCTCCATCTGCCGGTGGGAGCGGGAAATGGCGCAGCGAATGGTGCGGTTTCTGTTTCCGGTGCCACCCCTCCGCCCCCCACTGCCACGCAATGCTGCCGCCGCTCCAGTCCACCCGCCCATGTCAGCACCACCACCTCCGCCTGCAACTCCCACCACCCACACATCCAGCATGGACGCCACGCCTCCGTGATCATCGGCCAGGATCGATCGCCTCTGGCCAGCAGCGACAAGGACACGGCGGGCTCCCCCCTCTCCGGCCTGGACCACCAGATGACCCCGCAGGATGGCAGCGTGCGATCGGTGCGATCGGATGAGGGCTACCACAGCAACGAGTGCCACGAGGATGGACTCACGCCGCCCGAGGATTCCAGCGACAGCGAGAGTGAGCACAACTATGTGCTGGACTGTTCGAAGAAGGCGATCGCCCCCAAGGAGACGGTGATTGCCCAGGCCCAGAAGCCCAGCAGTTCGCCACCGGCTGTGGTTATGGCCAACACCACCACTAGTGCGATCAACAGCCATAGCTCGCCCACGGCCACGCCCATTTGCGAGTCGGACAAGAACGAGTACAGGAAGTTCAAGGTGAAGATGCCGCTGAAGTACGAGTTCAAGAACAAGAGCTGCGTGAAGCAGGAGCCCAGTCTGAAGGAGGTGGATCAGGAGATGTCCCTGCCGCAGGAGGAGGAGGAGGAGCAAGTGATGCACCCGGAACCCGACTCCATTTGCCCCTCGACCACCACCCACCTGGGCGATGAGCATATGCTGATGATGGAGAGGGAGCGGGAGAGGCAGAGGGAAAGAGAGCAGGAGAGGATTCAGGAGCGCGAGCAATCGAACCAGCAGCCCGCCTCCTCCACGGTCATTGTCCTGGAACACAATTCCGGTGGCCAGGCCCGCACCATTGTCCCACTGAGCAAACCCTACTACGAACCAGATCCCCCGGGCGAACGCTATCTGCGATTTGGCCAGCCCTCGTCGAGCATCCTGGAGACCATCCTGACCAGCCAGCATCGTCTGGAGGCGGCGGCAGCAGCGGCCAATGCCTGTCGGCAGGCCAATGCGGCCACGCCCCCTCCCACCTCGCCCACGGAGATGGCCTACAGCTACAAGAAGTCCCAGCGATATGGCAATGCGGTGAGTCCGGACAGCAGCTCCAACCTGGGCCAGAATCCCGAGCAGCTCTCCTCGTCGGCCGTGGTGGTGGGTGATCAGGAAATGACCAGAGCCACCCTGATCAAGGGAGAGTGCTCCCCACCACCGCCCAGCCACCATCACCACAACGTGATCTTCTCACCCTCGAGGCATGCGGCGTACTTGGGAGCCGGCGAGGCGGGTGGTCACTCACCAAGTCCGGGATATCCTGGTTACCCCCACTACGGAGCAGCAGCCACCTCGACCTTCCACTCGCCGCCGCACAGTTCCCATTCCCCCTTCGACCGCCAGTCGAATGCCTCGAGCGGAGCGGGCTCCGCCTCCAACTTGCATTTGTTGCAGACCAGCACCCAGATGCTGAATCACCCGCTGATGCAGCCGCTCACCCCGCTGCAGCGCCTGTCGCCCCTGAGGATCTCGCCGCCCAGCAGCCTGAGTCCCGACGGCAACTCCTGCCCGCGCAGTGGCAGCCCGCTGAGCCCCAACTCCCTGGCCTCCAGGGGCTACCGATCGCTGCCCTATCCCCTGAAGAAGAAGGACGGCAAGATGCACTACGAGTGCAACGTGTGCTGCAAGACCTTCGGGCAGTTGAGCAACCTCAAGGTCCATCTGCGTACCCATTCCGGCGAAAGACCCTTCAAGTGCAATGTGTGCACGAAGAGCTTCACCCAGTTGGCGCACCTGCAGAAGCATCACCTGGTGCACACGGGCGAGAAACCGCATCAGTGCGACATCTGCAAGAAGCGATTCTCGAGCACCTCCAATCTGAAGACTCACCTAAGGCTCCACAGTGGCCAGAAGCCGTATGCCTGCGACCTGTGCCCCCAGAAATTCACGCAGTTTGTGCATCTCAAGCTGCACAAGAGGTTGCACACGAACGACAGGCCGTACGTGTGCCAGGGGTGCGACAAGAAGTACATCAGTGCATCGGGCTTGAGGACCCACTGGAAGACCACCAGCTGCAAGCCCAACAACCTGGAGGAGGAGCTGGCCATGGCAGCAGCGGCTACCTCGGAGTGTTTGGATAAAGACCATCCCGAGCCGGACTCCCGAGAAGCCTACGAGCAGCTGACGCAGCACATGCATCCTGGTGTGCACCCGGGACTGAGACATCTCTCGAATGGAGGACAATCGCCACCACGCCTGATACCCCTGGGCAACCACATGGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCACCTGCTGATGGCCCAGCACTCGGTGGGTCCGGCCCCCATGCTACTGACCACCGCCAGTCAGCTGCCTCCGCCGCCGCCGCACCACCAGCAGAACTCGCCCAGCCGCCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCGGAGTCGGGGGCGTATCTGCATGGCCAGCACGTGCAGGCCCAGGAGAGCAGGCCGTCGGTCATCGAGTCCTCCAACCAGCCCATGATCATCGAGTGCACGTAG
Protein Sequence: MHGHHNHNHLQQQQPQNPQDQQPGAIMKAANHPQPHHPLSHPHPHQQHPHAQPHPHPHPHHKLSARRARSRSRSRSPSPDGNQDYDVTRMREEDFQRLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHQENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPETTIFGACKQAVEAEEEVDEEEEEAEGEDGKPRYSMPAPEIPADVAVSHITYVMGLHLPVGAGNGAANGAVSVSGATPPPPTATQCCRRSSPPAHVSTTTSACNSHHPHIQHGRHASVIIGQDRSPLASSDKDTAGSPLSGLDHQMTPQDGSVRSVRSDEGYHSNECHEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSSPPAVVMANTTTSAINSHSSPTATPICESDKNEYRKFKVKMPLKYEFKNKSCVKQEPSLKEVDQEMSLPQEEEEEQVMHPEPDSICPSTTTHLGDEHMLMMERERERQREREQERIQEREQSNQQPASSTVIVLEHNSGGQARTIVPLSKPYYEPDPPGERYLRFGQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQNPEQLSSSAVVVGDQEMTRATLIKGECSPPPPSHHHHNVIFSPSRHAAYLGAGEAGGHSPSPGYPGYPHYGAAATSTFHSPPHSSHSPFDRQSNASSGAGSASNLHLLQTSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDHPEPDSREAYEQLTQHMHPGVHPGLRHLSNGGQSPPRLIPLGNHMAXXXXXXXXXXXXXXXXXXHLLMAQHSVGPAPMLLTTASQLPPPPPHHQQNSPSRLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXESGAYLHGQHVQAQESRPSVIESSNQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00619380;
90% Identity: iTF_00529789;
80% Identity: -