Basic Information

Insect: Drosophila biarmipes
Gene Symbol: Clamp
Assembly: GCA_018148935.1
Location: JAECYG010000283.1:1312516-1316405[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00086 0.051 13.8 0.7 1 23 127 149 127 149 0.99

2 7 0.00018 0.011 15.9 0.7 1 23 362 384 362 384 0.97

3 7 4.7e-06 0.00028 20.9 0.1 1 23 390 412 390 412 0.99

4 7 2.7e-06 0.00016 21.7 3.2 1 23 418 440 418 440 0.99

5 7 2.9e-06 0.00017 21.6 0.3 1 23 446 468 446 468 0.98

6 7 1.3e-06 7.7e-05 22.7 0.4 1 23 474 496 474 496 0.98

7 7 5.5e-05 0.0033 17.6 0.1 1 23 502 524 502 524 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00086	0.051	13.8	0.7	1	23	127	149	127	149	0.99
2	7	0.00018	0.011	15.9	0.7	1	23	362	384	362	384	0.97
3	7	4.7e-06	0.00028	20.9	0.1	1	23	390	412	390	412	0.99
4	7	2.7e-06	0.00016	21.7	3.2	1	23	418	440	418	440	0.99
5	7	2.9e-06	0.00017	21.6	0.3	1	23	446	468	446	468	0.98
6	7	1.3e-06	7.7e-05	22.7	0.4	1	23	474	496	474	496	0.98
7	7	5.5e-05	0.0033	17.6	0.1	1	23	502	524	502	524	0.97

Sequence Information

Coding Sequence: ATGGAAGATCTTACCAAAAACATAATCTTCACAAATGCTATAAATGGGCAACCAGCTACAATTCAGTACCAGACGGCAGATGGCACGATTCTTAAACAGCCTAAGATTGAGGGTCAAAAAGCGGAGCAGCAGCCTACATTTTATTACACGACAAATGGCAATAATGGAACTGTCAATCTTGCACAGCTGGCCACCACGGATGAGAACAAGACGTGTTACATAGCCCAGCCTGTTGGCGGCTACAACTACGCCCTGGTCAATGGGATGCCACTCAATCAGGGCGCAGCACTAGGCATCGCCACGGTGGACGCTCAAGGACGCATCCAGATCGTTAATCAGAACAAGCCAATAGCAGCTAACACCATATCCAACATCAGCTTCAAATGTGATGTCTGTTCGGATATGTTTCCCCACCTTGCCCTTCTCAACGCCCACAAGCGGATGCATACAGAGGGGGAACAGCAGCAACAACAACAGCACAACACCCAGCAAGTAGGCAGCGACTCGATAGCCGTGGTAAGCGCCCAGGGTATAGTGCAGGCACAGAACATCATTGGAAATGGACAAATGGGCCAGATCCAGATAGTGTCTTCCGACACGCTAGAGCCAGTGCAGCAATCAGTGATGCAACAGCAAGAATCTAAGGCGAACAAATGCATAATCTGCGGTAATTCCGTCCATCAGCAGTCCAAACGCAAAGGACCAAAGCAGGTGCGTTGTGAACCCTGCATGCAGGCGGAACAAGCGGCACAACAACAGCTCTTTGTGGCACAGGACGGTCAAATGGCGCATCCCGTGCAGATCATATCAACCACACCTCAGGCCCAAGCACAACTGCAGCAAATTGTAGCTGCGCAGACAGGCGGTTCGACGCCCAAACGTGAACCAAGCAGTGGGTCTGGCCATCACCCAGTAAAAAAGCGAAGTTCCCAACAGATGGCAAAATGTCAGAAGTGCAATGGCTCTGGCGTTGTACTGGTCGGGCAGCACCACCACCCCGGACATGCCGGAGCGGGTGGATCAGTAAAGCAATCTGTTACTGTCAAGACTGAGTGTTCGTCGTGCAGGAATCCGTCGAAACCGTTTAGTTGCAATATATGTGGTGGTCTTTTCTCACGTTACTCAAGTCTTTGGTCACACAAAAAACTGCACAGCGGCGAAAAGAACTATAAGTGCAGCATCTGCGGATTGGCCTTTGCAAAAGCCGTTTACTTGAAAAACCATGCTCGTATTCACACAGGCGAAAAACCCTATAAATGTCAAACATGTGGCATGCAATTCTCACAGTCGCCCCATCTTAAGAACCATGAACGCACGCATAGCGGCGAACGACCCTACGTGTGCGGAGTGTGCGATAAAGGATTCGCGCGCCATGCTACTCTTTGGAACCATCGGCGCATTCACACTGGCGAGAAGCCGTACAAGTGTGAAATTTGCGGCTCAGCTTTTTCCCAAGCGGCGCACCTTAAGAATCATGCAAAGGTGCATTCTGGTGAGAAGCCCTACAAATGCGAGATTTGCTCGGCAGCGTTTGCTGATCGTTTCGCTCTTAAACGCCACCGCGGCATACACCAAAAGTACGGCCAAACGGCGCCGCGGCAGACTAGTAGTGATGGAATGATAGTGCACAAGCAGGAGATTCCTGACATGGATGACGAAGCCCAACAGGAGGTGATCATTGGAGGGTTATAG
Protein Sequence: MEDLTKNIIFTNAINGQPATIQYQTADGTILKQPKIEGQKAEQQPTFYYTTNGNNGTVNLAQLATTDENKTCYIAQPVGGYNYALVNGMPLNQGAALGIATVDAQGRIQIVNQNKPIAANTISNISFKCDVCSDMFPHLALLNAHKRMHTEGEQQQQQQHNTQQVGSDSIAVVSAQGIVQAQNIIGNGQMGQIQIVSSDTLEPVQQSVMQQQESKANKCIICGNSVHQQSKRKGPKQVRCEPCMQAEQAAQQQLFVAQDGQMAHPVQIISTTPQAQAQLQQIVAAQTGGSTPKREPSSGSGHHPVKKRSSQQMAKCQKCNGSGVVLVGQHHHPGHAGAGGSVKQSVTVKTECSSCRNPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIHQKYGQTAPRQTSSDGMIVHKQEIPDMDDEAQQEVIIGGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537677;
90% Identity: iTF_00524568;
80% Identity: -