Basic Information

Gene Symbol
-
Assembly
GCA_018148935.1
Location
JAECYG010000047.1:5826763-5828706[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0013 0.079 13.2 3.7 1 23 97 119 97 119 0.97
2 13 0.00052 0.031 14.5 2.8 1 23 125 148 125 148 0.98
3 13 0.00072 0.043 14.1 4.6 1 23 338 360 338 360 0.98
4 13 3.2e-05 0.0019 18.3 1.7 1 23 366 388 366 388 0.98
5 13 1.1e-06 6.7e-05 22.9 0.4 1 23 393 415 393 415 0.97
6 13 0.004 0.24 11.7 0.1 1 23 421 443 421 443 0.98
7 13 0.00098 0.058 13.6 4.3 1 23 448 470 448 470 0.97
8 13 0.00012 0.0073 16.5 1.5 1 20 476 495 476 498 0.93
9 13 0.011 0.63 10.4 4.7 1 23 504 526 504 526 0.98
10 13 4.6e-06 0.00028 20.9 6.2 1 23 532 554 532 554 0.99
11 13 8.7e-05 0.0052 16.9 0.3 1 23 560 582 560 582 0.99
12 13 0.0036 0.21 11.9 0.0 2 21 589 608 589 609 0.95
13 13 0.01 0.6 10.4 7.2 1 23 616 638 616 638 0.98

Sequence Information

Coding Sequence
ATGCCAACTAAAGTAAATGAGGAAATGGGACTTCCTGACGAGAATCATTTAAGGGAAGCGGAAAACCAGACATTTCCGTGCCAAGTGAAGGAGGAGTTCCTTGAGGAGGATGAGGAGTTCCTTGATGAGGAGGAGTTCTTTGATGAGGAGGAGTTCTTTGATGAGGATCCCAACGAGCAGTTTTACTCCCAGGACGAGCCCATTGAAGATGACTTCTATGAAAGTGGTCACCCCGATGAGCAAGTTCTAGAACTAGAACCTAGTATGGGCAACGAAAACTCCAAACCATTTAAATGCTGCCTCTGCCCGAACTCCTATCGGCTCCAATCCCATCTCATTCGCCACATTTTGGATCATGCGGCAGACCGACCATTTAGGTGCTCCACCTGCAACAATAGAACCTTTTCGACTAAACGCAGTCTAGATATACACTTAAGGACCCACAAGGACGAGGCATCTTTTTCGAATTCATCGAATCTGGACCCCCACGGAAGAATTAACACAGAGGAACAGGTGCTGGAGAAGGTCCTTGAAGAGGAATTTCCCGATGAGAAGATCCTTGATGAGGAGACCCCTGAGGAGGATGATTCAATAGAGGAGGAAGATGATTCAAAAGAAGAGGAGGACGAGGTGGAGTTCATATATGACAAAAGGAGCCAAATATCATCCGGCAAAGCTGAAGAAGTGATTGATTTCGAGGAGCAGATAGACGAACTAAGGGAAGGGGAATCCAGGTCGGAAGAAGAGACTCATTACTTTGAGGCCCAAGTGAAGAACGAACCCATTGAAGATGATTTTGAGGAGGAAGACGATTCCGTATTGGAAATGGCAAGTGATCAAGCCGACGAAGAAGTAACAGATGACGACATTGAAATAGAAGTCAAAAGCGAACCCATTGAAAGTAGTTTTCAAGAAGAGTTCAATCGCTTACTGGGAAAAGCAAACGTTAAACCCGATAATCAATTAAAAGTCGATGAGGTTGAAAGGGCCCGCCTCAATTGGAAAAACTCTTACAAGTGTTCCCAATGCCAGATAATGTTTCGGAATCGAGCCCATATGATGAAGCACTTCCTCAAGCACACGGGAGAACTACCTTTTGAGTGTAGCCAGTGCTCTAATTCGTATAAATCGAGAGTCTCCCTAAGGAAACACATGATAACGCACGGAGTGATGCCGTTCCAGTGCCCCCAGTGCTCCAAGGGCTTCGAGCAAAAGGCCTCCCTGAGGAGACACATTGGCATGCACCGGGAGGATCGGCCATTTAAATGCCCCCAATGCCCGAATTCCTACAGGGCGAGGGACATCTTAGCGAAGCACATAAAAGTACACGAGGAGAAGCCGTTCCATTGCCCCCATTGCACCAAGCGCTTCAGGGAAGAAGGTCCTTTGAAGAATCACCTTACCAGACACGAGAACGAACGGCCGTTCAAGTGCCCCCACTGCTCCAGGGCATTCGAGCTGGAATCCACTCTGAAGAATCACATGCCCAGACACACAGAAGAGCGGCCGTTCAAGTGCCCCCATTGCTTCCTGGGCTTCTTTCACGGAACCACGCTGAGAAAACACCTCAGCGTGCACACGGGAGAACGGCCCTTCAAATGCTCCTTCTGTCCGAAATCATTCAGGCTCAAGGACACCCTCAAACGACACCACAGAACCCACACGGGCGAGCGACCCTATCAATGTGACCAATGCGACGATGCCTTTGCGGATAAGACTGCCCTCAACATCCACAAGCGACGTCACGCGGGCGAGCGACCCAACGAATGCCCGGATTGCCAGGCAACCTATGTGGATAGTGGCAGGTTCACGAGACACTTAAGGGCCTACACGGAGGAACGACCGTATAAATGTCTCTTTTGCGACAAGACTTTCAAGTCCAAGCTCTGTATGAATAATCACTTCAAGTCTCACACCAAACTTCCTGGTGGAATTTGTATTTGA
Protein Sequence
MPTKVNEEMGLPDENHLREAENQTFPCQVKEEFLEEDEEFLDEEEFFDEEEFFDEDPNEQFYSQDEPIEDDFYESGHPDEQVLELEPSMGNENSKPFKCCLCPNSYRLQSHLIRHILDHAADRPFRCSTCNNRTFSTKRSLDIHLRTHKDEASFSNSSNLDPHGRINTEEQVLEKVLEEEFPDEKILDEETPEEDDSIEEEDDSKEEEDEVEFIYDKRSQISSGKAEEVIDFEEQIDELREGESRSEEETHYFEAQVKNEPIEDDFEEEDDSVLEMASDQADEEVTDDDIEIEVKSEPIESSFQEEFNRLLGKANVKPDNQLKVDEVERARLNWKNSYKCSQCQIMFRNRAHMMKHFLKHTGELPFECSQCSNSYKSRVSLRKHMITHGVMPFQCPQCSKGFEQKASLRRHIGMHREDRPFKCPQCPNSYRARDILAKHIKVHEEKPFHCPHCTKRFREEGPLKNHLTRHENERPFKCPHCSRAFELESTLKNHMPRHTEERPFKCPHCFLGFFHGTTLRKHLSVHTGERPFKCSFCPKSFRLKDTLKRHHRTHTGERPYQCDQCDDAFADKTALNIHKRRHAGERPNECPDCQATYVDSGRFTRHLRAYTEERPYKCLFCDKTFKSKLCMNNHFKSHTKLPGGICI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-