Basic Information

Insect: Drosophila biarmipes
Gene Symbol: -
Assembly: GCA_018148935.1
Location: JAECYG010000079.1:17366190-17368337[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 1.9e-05 0.0011 19.0 0.1 3 23 236 256 234 256 0.97

2 12 3.6e-05 0.0021 18.1 2.2 3 23 268 288 266 288 0.96

3 12 1.1e-05 0.00068 19.7 1.8 1 23 294 316 294 316 0.99

4 12 1.4e-05 0.00081 19.5 4.7 1 23 323 345 323 345 0.98

5 12 8.4e-06 0.0005 20.1 2.2 1 23 351 373 351 373 0.97

6 12 3e-07 1.8e-05 24.7 1.1 1 23 379 401 379 401 0.99

7 12 5.1e-07 3.1e-05 24.0 3.5 1 23 407 429 407 429 0.99

8 12 1.2e-06 7.2e-05 22.8 4.9 1 23 435 457 435 457 0.99

9 12 1.5e-05 0.00087 19.4 0.8 1 23 463 485 463 485 0.98

10 12 0.00055 0.033 14.4 0.5 1 19 493 511 493 515 0.93

11 12 0.00052 0.031 14.5 2.2 1 23 525 547 525 547 0.97

12 12 2.5e-05 0.0015 18.6 4.1 1 23 552 574 552 574 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	1.9e-05	0.0011	19.0	0.1	3	23	236	256	234	256	0.97
2	12	3.6e-05	0.0021	18.1	2.2	3	23	268	288	266	288	0.96
3	12	1.1e-05	0.00068	19.7	1.8	1	23	294	316	294	316	0.99
4	12	1.4e-05	0.00081	19.5	4.7	1	23	323	345	323	345	0.98
5	12	8.4e-06	0.0005	20.1	2.2	1	23	351	373	351	373	0.97
6	12	3e-07	1.8e-05	24.7	1.1	1	23	379	401	379	401	0.99
7	12	5.1e-07	3.1e-05	24.0	3.5	1	23	407	429	407	429	0.99
8	12	1.2e-06	7.2e-05	22.8	4.9	1	23	435	457	435	457	0.99
9	12	1.5e-05	0.00087	19.4	0.8	1	23	463	485	463	485	0.98
10	12	0.00055	0.033	14.4	0.5	1	19	493	511	493	515	0.93
11	12	0.00052	0.031	14.5	2.2	1	23	525	547	525	547	0.97
12	12	2.5e-05	0.0015	18.6	4.1	1	23	552	574	552	574	0.97

Sequence Information

Coding Sequence: ATGGAAAGCTCATCGGTGGCCGCCATGGAAAAGAACTGCCGCGCCTGCGCCGAACACTCGCCCGTACTGGTGGACCTCTTCTCCGCGGACATTTGCGACCCACCCGTTTGGGAGATGCTGAATTCCTTTCTCCCCGAGAACTGCCGCGTCAACCGAGATGAAATGCCGCAGAAGATTTGTCCCCCCTGCCTGGTGGCCACCCAGAATGCCTTTCACTTCAGGCACAAGTGCGAACAGAGTTTCCAGTACTTTGGCCACCTCATCCAGCTGGAAAAATCCGCTGCCACAAAACAGGGCAGAACTAGGAGCAGAAGAGGAGACCAGAATGCTCTAGTAGATTTCGAGATGGTTGGTTGCGAGGATCCGCTGGACACGAATGTTTCTGGAAGGGACGAGGACCGGCTTGTTTTGAAAACCGATAATGATTTGCAGCCAACGGAGGAATTGCCAATTAATGAACAGGACGATCAGCCGCTGCAGGAGGTCTTTGAAATAACCATGAGCGATATAAAAACTGAGGAAGAATTGTCCAACGGCGATGCCTTCGAAGATGCCTTTGCAGAAGACGATAATAATGTTGATGAACCTGAATGCGAATCTGATGAATGGTCTCCTGACTGGTCGGACCAAGAGGATGAAGAGGAGCTCTGGATGCAAGGCAAGGGAGAACCATCCACGACCAACGACAAGAGTAAGTCGCTCCTGTGCACAGAGTGTGGAGTGACCTATTCCTCGCAGAATGCGTTGCAGAAGCACATTGCCAGGCACAAGACGCAGAATGATCCTCAAAAGCCGCACCTGTGCGACTTCTGCGGCAGAGGATTTCGCACCAACCCCCAGCTGATATCCCACAGGCGCAAGCACACCGGAGAGCGTCCTTTCAAATGTACCCTTTGTCCGAAAGAGTACACAAATGCCCCTACCCTGAAGTTGCATATGCACACCCACGACGAGCAAAGAAAAGTCCACACGTGTCCTCAGTGTAATAAAACCTTTTTCTCCAGGCGCAACCTTAGGGATCATGTGAAGCGTCACACTGGAGAAAGACCATTTGAGTGTCCCGAATGTCATCAGACCTTTACAAAGAACTCGGGCCTTAAATTGCACAGTCGTCTGCATATGGCGGAAAAGCCCTTTAAATGTGAGCTCTGCGGCAAAGGATTTGTTCAGAACCAGCATTTGATCACCCACTTGCGCGTCCACAACGGGGATCGCCCGTTCAAGTGCACTGAGTGCGACAAGTCGTTCTTCGAGAAATCCAACATGCTGAAGCATCAGCGGACGCACACCGGAGAAAAGCCTTTCAAATGCGAGGAGTGCGGCCAGGCATTCGCCCACAACCATCATCTGAAGAGTCACCTACGCATCCATACAGGTGATAAGCCCTACAAATGTGACCAGTGTGGCAAGGGCTTCTGTGCGAATCAGTCTCTGGCAAAGCATATCCTTTGGCACGAGGAAAACAAAGATCGTCCTTTCAAGTGTCCCAAATGCCCCAAAGCCTTTGACTCACTGCAGAGTTTACGGGGCCACGATAAGGCGCACAGAAAGCCAGTTGAGCCAAAAACGCTGCATCAATGCCCACACTGCGATGTCAGGTTTGCCCTAAAGAAGACCTTGGACAAGCATATCGGTAGTCATAAGATTCGGCCACACCCATGCCCGCATTGTGACGAGGGATTCTTCTCGGAGAAGAGCTTTAAAAGACACCTCCGCACGCACAAATCGAAGGAATAG
Protein Sequence: MESSSVAAMEKNCRACAEHSPVLVDLFSADICDPPVWEMLNSFLPENCRVNRDEMPQKICPPCLVATQNAFHFRHKCEQSFQYFGHLIQLEKSAATKQGRTRSRRGDQNALVDFEMVGCEDPLDTNVSGRDEDRLVLKTDNDLQPTEELPINEQDDQPLQEVFEITMSDIKTEEELSNGDAFEDAFAEDDNNVDEPECESDEWSPDWSDQEDEEELWMQGKGEPSTTNDKSKSLLCTECGVTYSSQNALQKHIARHKTQNDPQKPHLCDFCGRGFRTNPQLISHRRKHTGERPFKCTLCPKEYTNAPTLKLHMHTHDEQRKVHTCPQCNKTFFSRRNLRDHVKRHTGERPFECPECHQTFTKNSGLKLHSRLHMAEKPFKCELCGKGFVQNQHLITHLRVHNGDRPFKCTECDKSFFEKSNMLKHQRTHTGEKPFKCEECGQAFAHNHHLKSHLRIHTGDKPYKCDQCGKGFCANQSLAKHILWHEENKDRPFKCPKCPKAFDSLQSLRGHDKAHRKPVEPKTLHQCPHCDVRFALKKTLDKHIGSHKIRPHPCPHCDEGFFSEKSFKRHLRTHKSKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536909;
90% Identity: -
80% Identity: -