Basic Information

Insect: Drosophila basisetae
Gene Symbol: Glis3
Assembly: GCA_035041595.1
Location: JAWNLB010000070.1:8509152-8513929[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 8.5 5.2e+02 1.3 2.4 3 23 429 452 427 452 0.89

2 5 0.18 11 6.5 0.4 1 23 461 488 461 488 0.88

3 5 9.4e-07 5.8e-05 23.2 0.5 2 23 495 518 494 518 0.97

4 5 0.00094 0.057 13.7 0.8 3 23 526 548 524 548 0.92

5 5 3.8e-05 0.0023 18.1 0.4 1 23 554 578 554 578 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	8.5	5.2e+02	1.3	2.4	3	23	429	452	427	452	0.89
2	5	0.18	11	6.5	0.4	1	23	461	488	461	488	0.88
3	5	9.4e-07	5.8e-05	23.2	0.5	2	23	495	518	494	518	0.97
4	5	0.00094	0.057	13.7	0.8	3	23	526	548	524	548	0.92
5	5	3.8e-05	0.0023	18.1	0.4	1	23	554	578	554	578	0.94

Sequence Information

Coding Sequence: ATGTCTTCCACAatgaagcaacagcaacttccAATATCCATTCCCAATCACAGCGCCGAGATGTTCACCAAAACTAAATCATACAATGAGAGTGTTTGCTATGATGCTTTCATGTCGCCACCATTAAGTGCCAGTGTTGGCAAGGGACACGATGATTTTCAGGCGCCCAAAGTCAATTTCACCAATAATACGAATTTTACCTGCGCCGAATTGCAGTTTCCGGACTTTTCACATCTATGCTTCGCCACGGAGACACCGAACTCTGTGTTTAGTGACTATAATAACTATACGGGACCGGAACAGGACAGGGATAGGGATGatattgtgtgtgctgctgccgGGCAAACGGGTATGCCCTATCAGCAGGGTCAGTACACTCAGCTAAATCGCGAGGATGTCTTTCGGTTCGAGCCGGAGGACATTGCACGACTAACGGCAGACAATGGATGTGGTGGAGGTGGAGCCTTCGCTGAATCGATCGATGGCTTAATGCAGGTGCCACAAACACCCTTCACGCCGTGCAGTGGGCCGAGCGGGTGTCAATTGGGTGGTTTGGCCGCCCAGGTTGTCGAGCCGGTCGAGTCTCTCAATCAGGATATTGATTACTTTAATTATGATGAAGTTAATTGCCAATCAAAAAATCAATCACCCTGCTCGTCGCCACATTTGGACGCCTGGTTGAACTTTAACCTCAGCGAAATATCGCCGGCGGAAACAGTGCGCGAATCCTCACCGaaattatgcaacatttaCGAACAACAACTGGCGCATATTAAAGTggaacaaacacaaacacagcaaAAGTTACCATCAATGAGCTCCACTTTTGGCACACCCAAGTGTACACCGGTGTGTGGCACTTACGGCGATTACTCCAATCTTTACAACAACCAAAGTGTTTacggaaatttaaatgaatacgCAACggaacattttcaaaataacatCTCACAAGTTATTGAGAAACCCAATCGTGAACATAAAGTTATTTGGACAATTGATGAATTGGATGAACTGAATGCAGCCCTGGTGCTCAACGATCAGGTTCAGCAGGACTGTGAGTCCAAATTTGATAAGTCTGACTTCGCATTGGACAATCTGCCAACTGTAACAGTGGAAACCCTGAGCGAAGAGCATCTCTTGACGGCCAACATCAGCgatgatgacaatgacaaggatgatgatgacattGATGATGTGTTTGCGGCACCCGTCGAACTGGAGAGGAGACCTGAATATGCCGATTCCATTGATGGTGAGATTGAGCAGCCCGGTTCGCTTATTTGCCACTGGTCCGAGTGCAACATGGAGTTCGCCCatcagcaaatatttgtggagCACATCGAAAAGTGTCACGTGGATGTGCGCAAGGGCGAGGATTTCTCCTGCTTCTGGCTGGACTGCCCCAGACGCTACAAGCCATTCAATGCCCGCTACAAACTGCTCATCCACATGCGAGTCCACAGCGGCGAGAAGCCCAATAAGTGTCCGTTTCCGGAATGCAATAAGGCATTTTCACGTCtggaaaatttgaaaattcatCAACGCTCGCACACAGGCGAACGTCCTTATGGCTGCCAATATAAGGGTTGCCTCAAAGCCTTTAGCAACAGCTCGGATCGTGCAAAGCATCAAAGAACGCACTACGATACGAAACCGTACGCCTGTCAGCTGCCTGGCTGCACCAAACGGTACACGGACCCCTCAAGCCTGCGTAAACATGTCAAAAATCACGGACTTATGCGCCGCAAATCTGCCAGCGGCGGCGCCACATCCACGTCCTGCAGCAAAAAGTCGGGCAAGACACGCCGCCATTCCGAATCGTCTGCATTATCAACAAGGGGACCGTTGGTTGGTGCACCACCCGTTGAGCCGCGTACAgagcgcagcagcagttgcagcgaGGCAGCGCATTTAATCCAATTGGGTGGTGGCCAGAATAGGGATATGCTAACGAGGGAAGTGGTGGCATCAACTTCGTCAACAACAGACCGCAGCTATGTCTGCAGCAATGAGAACGTTGCAACTAAtaacaattcaataaaatttaatgagttGTCAAATTGCATTGTCATCATTgagcaaaaccaaaatgaggcgacaccaacagcaaatgcaacagcaattggcTGTCACGATAATAGatacaacaacacaacaatcGCAGCGACGACTACATATGACGGGTTTAACTACTACAATAACAGTCGAGCTGGCGAAGGTgacaatgtaaataatatatattccgTAACGGAAACGGATGCATTGagcacttgcagcagcagtgccagcaatagcaacaattatAAAACCAACAATCAGGACAGCTGCAATCAtgataatattcataaatttaatgatcTGGAACAGCTGCTAAATTCAACAACGGAACAACACAATTTAAGCACTGATTTTAATACAACGGACAATAAGTGTCAATTGAATGAGTTTGTCTCATTCGAATATGTGCGAAAGTATCTAACGGATGCATTCGAGTCACCCAGCGCAGAGCACAGACCAAAGAGCCCAGTTACAAATTCTCAAATCGTCAACGATTTCGAAAATTatgatattcaatttatttga
Protein Sequence: MSSTMKQQQLPISIPNHSAEMFTKTKSYNESVCYDAFMSPPLSASVGKGHDDFQAPKVNFTNNTNFTCAELQFPDFSHLCFATETPNSVFSDYNNYTGPEQDRDRDDIVCAAAGQTGMPYQQGQYTQLNREDVFRFEPEDIARLTADNGCGGGGAFAESIDGLMQVPQTPFTPCSGPSGCQLGGLAAQVVEPVESLNQDIDYFNYDEVNCQSKNQSPCSSPHLDAWLNFNLSEISPAETVRESSPKLCNIYEQQLAHIKVEQTQTQQKLPSMSSTFGTPKCTPVCGTYGDYSNLYNNQSVYGNLNEYATEHFQNNISQVIEKPNREHKVIWTIDELDELNAALVLNDQVQQDCESKFDKSDFALDNLPTVTVETLSEEHLLTANISDDDNDKDDDDIDDVFAAPVELERRPEYADSIDGEIEQPGSLICHWSECNMEFAHQQIFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPECNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNHGLMRRKSASGGATSTSCSKKSGKTRRHSESSALSTRGPLVGAPPVEPRTERSSSCSEAAHLIQLGGGQNRDMLTREVVASTSSTTDRSYVCSNENVATNNNSIKFNELSNCIVIIEQNQNEATPTANATAIGCHDNRYNNTTIAATTTYDGFNYYNNSRAGEGDNVNNIYSVTETDALSTCSSSASNSNNYKTNNQDSCNHDNIHKFNDLEQLLNSTTEQHNLSTDFNTTDNKCQLNEFVSFEYVRKYLTDAFESPSAEHRPKSPVTNSQIVNDFENYDIQFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567118;
90% Identity: iTF_00499892;
80% Identity: -