Basic Information

Insect: Drosophila basisetae
Gene Symbol: Hivep2
Assembly: GCA_035041595.1
Location: JAWNLB010000144.1:7990228-7999383[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0016 0.095 13.1 0.4 2 23 258 279 258 279 0.98

2 8 0.00024 0.015 15.6 3.2 1 21 285 305 285 309 0.90

3 8 0.0094 0.58 10.6 0.4 1 19 974 992 974 995 0.93

4 8 2.9e-06 0.00018 21.6 2.0 1 23 1753 1775 1753 1775 0.99

5 8 1.2e-05 0.00075 19.7 5.3 1 23 1781 1805 1781 1805 0.92

6 8 0.00055 0.034 14.5 3.5 2 23 2294 2315 2294 2315 0.97

7 8 0.00083 0.051 13.9 1.2 1 23 2321 2345 2321 2345 0.91

8 8 0.0027 0.16 12.3 2.7 1 23 2366 2390 2366 2390 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0016	0.095	13.1	0.4	2	23	258	279	258	279	0.98
2	8	0.00024	0.015	15.6	3.2	1	21	285	305	285	309	0.90
3	8	0.0094	0.58	10.6	0.4	1	19	974	992	974	995	0.93
4	8	2.9e-06	0.00018	21.6	2.0	1	23	1753	1775	1753	1775	0.99
5	8	1.2e-05	0.00075	19.7	5.3	1	23	1781	1805	1781	1805	0.92
6	8	0.00055	0.034	14.5	3.5	2	23	2294	2315	2294	2315	0.97
7	8	0.00083	0.051	13.9	1.2	1	23	2321	2345	2321	2345	0.91
8	8	0.0027	0.16	12.3	2.7	1	23	2366	2390	2366	2390	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCAGGTGGCAAGCAGCGCAGCGAGCaatgtagcagcaacaacaacaacagcaacaacaataccagcCACAgccaacaccaccagcaacaataacaacaaccagaacagcaacagcaacaacaacagcagcagcagtgagtatccaacaacagcgacagcaacaattgtcgaTGGCTGGACGAGCTCAACCAATTTGCgttatttgcacaaaaagtTTAAGCGGCTGGCGAGCACCACCGAACCAGAGTCGGTGGATGCAATGGCAGCGATGCGCACCACATCGCTGTCATCGAATAGCTCGTTATCGCCACCGCTGCCAGTGGCCGCAGCACCGCTGCTCAATGGACATGTGACGGTGAAGGTTGCTCCCTTGCTGCCGGCAAGAAATGTAGAATTCAGTGCCAATTTCGTAAATGCcaacgacaacatcaacaacaacaacaacaacaacaataacaacaacagtcatgatgagagcaacaacaacaagcacggcaatgttgctgttgttgctggtgcgcCCCGAACACGCACGCCCCTCAGCAACAgtaatagcaatagcaatattaACTATGCCAGTAATGCAACACTGTCGCCAGCAACATTcgcacagcatcagcaacaaacgcagccaacgccagcagcaacagcagccgcaacaacaacaacagcaacagcagctgtagcagcaacaacaataatacaaacagcaccagcaacagttgcagtcgcaggaTTGGGCGAGAAAACTAGTCGCCCCAAGTGCCCCTATTGCAATCTGATCTGTGCAAAGCCATCGGTGCTGGAGAAGCACATTCGTGCCCATACCAATGAGCGACCGTATCCGTGCAACAACTGTGGCATCGCCTTCAAAACGAAGAGCAACCTGTATAAACACTGccgttcccgttcccattTGGCGCGCATGCGTGGCCTCGATGTGCCAGCCAATGAGACGGACGGTCTGTCCGACCAGGACGGCGACGGGGAgctgagcaacagcagctccgaGCTACTAAGCGTCGAAGTTTTGAGTCGCACAGATTCGCCTTATGATGAGGCAATGGCCTCGCCGacgccatcgccatcgacGCTGTCGGCGGCGAAGAGTACGTatctgcagcagccgcaactgcaacagcatatgctgcaacagttgccgcttGGCTCACCAGCAGCCGGAACACTGCCGCCCGCCCCGCCCGCTGACTCGCTGCACTCGGCGACCGCTCAGCTTCGCCAGTCGCTCGAATACAAGCCATACAAGCCCAAGTTTCACAATGCATCCCTCTATGCGCCCGGCACCCTcaaggagcaacagcagcaacaacagcaacagcagcagcaggtactgcaacagcaacagcagcaggcgttgctgcaaccacaacagcatcaacacaAACTATcagcgcagcaacagcagcagcagcaaccatcGCTGGCGCATCCAACGCTCTCGCCCAGCACCCAGTTGAAGCTCAACAATCACATCAATTCGcatcagttgcagctgcagatgcagcaccagcaccaacagcagcagcagcaacagcatttgcACGCCCAGCAATCCTTGCTGCTGGCGGCTGCAGCAACCAATCCGGTTGCATTGTCTGCattgccaccgccgccgccgggCGTTTATTATTTGGGACAGCCGCAGTATTATAatccaactgcagctgcaatgcATCAACATGCGCTGGCCATTCAgcagatgcagttgcagcagcactttcagctgcaacagcagcagcagcaacagcagcagcagcagcaacagcagcaccagcaacagcagcaacagcagcaacagcagctacagcatcaccaacagcaacaacagcagcagcagcatcaccaacagcagcagcagcaacactcacCATTGCTGAAggcgccacagcagcaacagcagcagCTGTTGCGCTCCACTAGccaacagcaggcagcagtgattgcaacaacagcagcgctgccagcaCCAGCCACACCCAACCCGCCAACCAATCTGAGCAGCTTTGCCAGCTCAAGCGGCGGAATGCAAGTGAATGTGGAAAAGGTGCAGGAGCACATCTCCAAGCTGATCTCACAGAACGAGGCGATTGTGGAGAATAAGGAGATACTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGTTCGCGCAGCttcaacaatgccaacaacaatagcaacaataacagtagcagcaacagcaacatcaacagcagcagcagtataccaacagcagcgcacgccaacagcaacagtaacaacaacaacagcaatcagcagCTGGGCGAGACTAAAGTGAACCTGGCACAGGCCATAgtacaaaaacagcagcaacagcaacagcagcatatgcaacaacagttgcagcagcaacagtaccAATTatacttgcaacagcaacaacaactggagcCGCCTGTGAATGGTCTGCtgaagcgcagcagcagcagctctgcAAGCAGTACAGCCAGCAGCGGCTATGCCAGCCTTAAGGGCACAGCGACCACAACACAAATCGCCGCAGCCACTCTAAATGTgaaacagttgcaacagttgccgccgccgccatcgccgttgccgttgcaacagttgcagtatCGCCAGGATCCGTCAACGCCAGTGCCcaagctggagcagcagcagcagcagcagttgcagcaacccTTGCCACTGAATTTGTCTGCCAAGCCCAAGCCGTCGCTAGCAATGCCAGCAAAACCAACgccaacagtaacagcagccgcagcagcatcagcaacaacaactgttgttgccaagagcacaacaacaacagcgccagCGGCAGCACCGAATATATCCATAATCAAGAATCTGCTGTTGAATGCACGTGGCCTGGCAGTGCCAATTGGCGAGGGCGATGATGCCGTCTACTCCTGCCCCATTTGCGCCAGTAAGTTTCGCAGCGCGGACGAGCTGAAGCACCACAACAGCACCTACTGCCAGGATGCGAATAGCAGTGCACCGATCAGTCCAGCCTCATCGCCGAGCACCAAATACTTTCGCTCCAATTCCATATCGTTTAGTCTGCCAGAGCTCCAATCGCACATGGCCAACTCGAAGAATCCGTTGTCGCTGGCCAAGCTCGCCAAGGTTGCCTGGTCGCAGCTAAAAACCAAGCCGAGCAGCCTGGTTCTCAGTCGTCTCAGTGCGGCACAGTCTCCCGCACGCACCTCAACCGTCACAGCGGctatcaacagcagcaccagcagcatcagcaaccacataaacagcagcagcagcatcaatcacaacagcagcagcaatcacataccagcaacagcagcaacagctgttgtaATCCCGCCCAGCATTGATGCAACCAGCGTTGCCTTGCGTTTTGTGGACGCACCGCTGCCATCGCCGGGGCCGCTGCTCGGCAAGACGCCGCTGGTGGATTATGCGGCGCCACGCAAAGCGCCCGATGCCCAGGTGGTCATCACGAAAATGCACGAGGATCGCCTGGAGAACATTATCGTTGAGGCGCCATCGAAACGGCTCAAGCTGAGCAGTTGCGAGACATCGTTCACGCTGCCATCTGTCGTCGATATGCTCTTTGCTGGCAATCCAGAGTTGCAGTTCAGTGGCAAGGAGGAGCGTTTGCGTCGCTTTACCTCATCCGGCGGCACCATGATACCCATTTCGGAGTGTCCCGAGCTGGACAAGAGTCCCAAAATGATACGCACTCCCCTGTTGTCCGGCGGCAGTTTCCAGGAGATGTCGCCACGTCTCAGCGACATCAAGGAGCGCAAACTACtcgctgccaacaacaataacaacaacaacaacaacaataataataacaatcataataatgGTTTTCTGCTCAGCGCCTCCAACACGCCGCATCATTTCCAATTCCCACCAATCAATTCGATAACCGCCTTCAATCCGCTCACCCTGCCACCcatgagcaacagcagcggcaccagcagcagcagcaacattgtgGATAAAGCGATACCCTATGTGCCGGGCATACCTGGTCCGGGCAGCTTATCgttgctgccaccgccacTTCAGGTGCAGCGTGGACGCAGCCCCAATCGCAAACAGCCCAGTCCCAATACGAATGCCAATCTCAATATCAATCTCAATCCGCTGCTGGCAGCTGAGGGCCCACTCAAGGCACTCTCGCCATTCGGTGGCGTACAAAATTTGCCCAGCGAATTCAGTCGCCAACCACCAACGCCAGCGCAACGCAATGCGCTCCAATggacgaacagcagcagcaacaacagcagcaataagcTGCCAGTGATTGTGGCCGACAGCACGCTGACCAAGAAGCCACCATTCAATTTTCTACGCATGGCGGATAATGTGAAGAGCTCCGCTgtgcaggagcaacagcaacaggcccAGGCACTGGCAATGGGTATGCTGGAGGTGCGTCACTTTAATTTCGATAATGTGAACAAATCGCAGGAGGCGCTGGCGCCGCTGCATGTCGACACGCCCgatgaggcagcagcagcagcagcagtagctgcaatcaaaacaacaacaacaaccactgcaATTCTAGTAGCTGCAACAGCCGCAACTAGCAGTGCCAAGTCGAAATTCTTGCGACCCACCAGTCTGCCCCTCAAGCCAGGCACCTTTACCCCAAAGCGACATCATGGCATCACACCGACTGCCAATACACTGCCCTTGATCTCACCGGAAACCCCGAGACCCTCCAAGTCGTGCGTGCAACTCTATCTGAATGGCCATGCGTACACCTATCTGGGACTCAAGTGCAGCACGAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCCTCGTATGTGGCGGGCATGCACAAGCTGTCCATGTACAGTGTGTGGCAGGTGTGCGAGGAGAATCAGCCGCATCCGCTCGGTTTCAAGCCCAAACAGGTGATGGCTCTCTACGATTCCAGGCAAAAGATGCTCGGCACTGGTTGCACCACAGCAATGGCGGGTGCCGGCAAACTGCAGTACTCTGTCTTCAGTTCACAGGAAACGGTTAGCACGTGCTCAACGACGGCCAACGGACAGAGCAAGTTCTACCAGCACCAGTTGAAACAGCCGCCGGCAATTGGCGCGCTCAGCGAGGCGAATGTGGCAGCCAAGGCCAGCGAGGAGGCGGCTGCCAAGAAGCTGGAAACGGGTCAGCTATTGGTCGGTGGCTACGAGTCGCATGAGGATTACACGTACATTCGTGGACGGGGGCGTGGTCGCTACGTCTGCTCCGAGTGTGGCATACGTTGCAAGAAGCCATCCATGCTCAAGAAGCATATACGCACCCACACCGATGTGCGTCCATTTACCTGCAGTCACTGCAATTTCAGCTTCAAGACAAAGGGCAATCTCACCAAGCACATGCAGTCGAAGACGCACTTCAAGAAGTGCCATGAGCTGGGCATCAATCCGGGTCCGATGCCCGCCGATGGCGAATTCCTTGATGTCGATGACTTTGATCAGCAATCGTCGACATCGGCAGGCGGACGCACCTCCTCCATGGCCGGTGAATCCGATTCGGATGACTACAGCGACAACGAGTCCGAGAGCAGTGACACCGATGAGTCCAAGTCGCGCATGAAGGAGCATGAGGCGGCACGGGgtctgctgtcgctgtcgatgACGCCGCCGATACCGCAGAGTGTTTCACCGTATCCGGCACTGGTCCAGGATACGCCGGCTGCCAGTCCAGCGAACAGCATTGGCTCCTCGGCTGGCAGCGCAGCTGGCAGCGGTTCGCAGCCGAAGCGACAGGTTTGCTCGTTTACGTCGCCAAAGCCGCCGTTTGACTACCAGAAGCAGGAACAGTATTACTCCAATCCCGAGGAGTCCAAACCCAAGCGCGGGGTGCCCAACGATGAGAGCAGCGCACCCATGGATCTGACCAAGCCCCGTCCAATGCCCAGCATTTCAGTGGCGGCCTCGTCGCCCATAGCCGACCAGATGCTGGCGCAGACACCCAAATCGCAGGCACAGCAGATGCGAGACGTAATCTTTGGCGCGGGCAACAACGAGTGCGGCTTCATGAAGACCCTAATCTCTGTCTCCGACAAGGTGCGCATCTCTGCCGAAATTGAGGAACAGGCAAAGCGCGAAAGCGAGGGCGAAGATGTCCTCCTGCAGACGTACATCAAGGAGCAGGCGCTGCAGCATGCCAAAATGAAGCAGAGCCAATTTAGTCGCAGCTACCTGGTCACTTCCACCACCAACTCCAACACGAACTGCTCCAACTCTACCTCTACCACGAGCAGCGTTAGCATTAGCTGTGCTGTGACCACGCCCATTGTTAATAGCAAGCCACAGTTGAACATGGCTGAGCTGCCCAGCATTGAGGTGCACGAGGTGAAGACACCAGAGTCGCCAACGCCATCGCCGGCACTTGTCAAATCCGCCGAGGAGAGTGAGGAGAGCGAAACGCAATCGGATCAGGAGAAGCCAAGCCTAACAACACCCATTCCTGTGCCAGTCACCGTCTCTGTCTCAGTTGCTGTACCAGTTTCCAGCACCAAGTCGACTGCAGAGATTCAGCAGCCGCACAATGCCAATTTGCCTGCTGCAGTGCAACAGCCAGATGCCACCGATTTTAGTGGCgtactcagcagcagcagcagcaatagcaacaaaaatagtaacagcagcagcggcagcagtggATCAACTGCACCCACGCGTATTGTGGTCGTCGGTGAGGATGGCTTCAAAACGACACCGACCAGCGGCAGCAACGAATTGCAGTCTGGCggcgcaacagcagctgcaacagcagcggcaccaGCAGGTGCAACGTATACGAATCGTGTggtgccaccgccaccgccgccaatAGCGAGTGATGCGCGACCCACTTGCACCGTTTGCAACAAGACGTTCCAGCGAACGCATCAGCTGTCGCTGCACATGAACATCCACTACATGGAACGGAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGCACCCAGGGTCACCTGCAGAAGCACGAGAGGAGCGAGGCGCATCGCAACAAAGTGATGATGACATCAACGTTTGGTGTGCCAACCACATCCAATCCGCGTCCCTTCGAGTGCACTGATTGCAAGATTGCGTTTCGCATCCACGGCCATCTGGCCAAGCATCTGCGCTCCAAGACACATGTGCAGAAGTTGGAGTGCCTGCAGAAGTTGCCATTTGGCACCTATGCCGAGATCGAACGGGCTGGCATCAGTCTGACGGAGATCGATACCAGCGACTGTGAGAATTCGCTCATCTCGCTCAAGTTGCTGGCACAGAAGCTGCTCGAGAAGGATCCGAACAAGCTGAGTGGCTACACAACGCCGTCGGGCATGCTGCAGCTATCGGCGGATGCACCGGCTGCCGGCCAGGACAGCGCCTCCGAGGATGGCTTCAGTGCGGCGAACAGTGCCGCCGCCTCGGCCATTGCCTCGCTGGACAACGACAGTGCCGGCAACACACCGAAGCGTGCCAGCTCCATGTCTGAGGATGAGACGCTCACCAACGGACTCGGCctcagtcacagtcacagccatAGCCACAGTCTGAAGCGGCGTCTGCAGAAcagcagcttcagcagcaATGGCGATGAGAGCGACAATCCAACGGATACCactggcagcggcagtggcagtggcagcagcgagAAGCGTGCCAGAAGCAACACAAATGAAATCATCACGCTGCCGACGCCGGTGGCTGTGTCGACGGCAACGGCCAGCAACTGa
Protein Sequence: MTLQQVASSAASNVAATTTTATTIPATANTTSNNNNNQNSNSNNNSSSSEYPTTATATIVDGWTSSTNLRYLHKKFKRLASTTEPESVDAMAAMRTTSLSSNSSLSPPLPVAAAPLLNGHVTVKVAPLLPARNVEFSANFVNANDNINNNNNNNNNNNSHDESNNNKHGNVAVVAGAPRTRTPLSNSNSNSNINYASNATLSPATFAQHQQQTQPTPAATAAATTTTATAAVAATTIIQTAPATVAVAGLGEKTSRPKCPYCNLICAKPSVLEKHIRAHTNERPYPCNNCGIAFKTKSNLYKHCRSRSHLARMRGLDVPANETDGLSDQDGDGELSNSSSELLSVEVLSRTDSPYDEAMASPTPSPSTLSAAKSTYLQQPQLQQHMLQQLPLGSPAAGTLPPAPPADSLHSATAQLRQSLEYKPYKPKFHNASLYAPGTLKEQQQQQQQQQQQVLQQQQQQALLQPQQHQHKLSAQQQQQQQPSLAHPTLSPSTQLKLNNHINSHQLQLQMQHQHQQQQQQQHLHAQQSLLLAAAATNPVALSALPPPPPGVYYLGQPQYYNPTAAAMHQHALAIQQMQLQQHFQLQQQQQQQQQQQQQQHQQQQQQQQQQLQHHQQQQQQQQHHQQQQQQHSPLLKAPQQQQQQLLRSTSQQQAAVIATTAALPAPATPNPPTNLSSFASSSGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNSNNNSSSNSNINSSSSIPTAAHANSNSNNNNSNQQLGETKVNLAQAIVQKQQQQQQQHMQQQLQQQQYQLYLQQQQQLEPPVNGLLKRSSSSSASSTASSGYASLKGTATTTQIAAATLNVKQLQQLPPPPSPLPLQQLQYRQDPSTPVPKLEQQQQQQLQQPLPLNLSAKPKPSLAMPAKPTPTVTAAAAASATTTVVAKSTTTTAPAAAPNISIIKNLLLNARGLAVPIGEGDDAVYSCPICASKFRSADELKHHNSTYCQDANSSAPISPASSPSTKYFRSNSISFSLPELQSHMANSKNPLSLAKLAKVAWSQLKTKPSSLVLSRLSAAQSPARTSTVTAAINSSTSSISNHINSSSSINHNSSSNHIPATAATAVVIPPSIDATSVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENIIVEAPSKRLKLSSCETSFTLPSVVDMLFAGNPELQFSGKEERLRRFTSSGGTMIPISECPELDKSPKMIRTPLLSGGSFQEMSPRLSDIKERKLLAANNNNNNNNNNNNNNHNNGFLLSASNTPHHFQFPPINSITAFNPLTLPPMSNSSGTSSSSNIVDKAIPYVPGIPGPGSLSLLPPPLQVQRGRSPNRKQPSPNTNANLNINLNPLLAAEGPLKALSPFGGVQNLPSEFSRQPPTPAQRNALQWTNSSSNNSSNKLPVIVADSTLTKKPPFNFLRMADNVKSSAVQEQQQQAQALAMGMLEVRHFNFDNVNKSQEALAPLHVDTPDEAAAAAAVAAIKTTTTTTAILVAATAATSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKMLGTGCTTAMAGAGKLQYSVFSSQETVSTCSTTANGQSKFYQHQLKQPPAIGALSEANVAAKASEEAAAKKLETGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCHELGINPGPMPADGEFLDVDDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPALVQDTPAASPANSIGSSAGSAAGSGSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPNDESSAPMDLTKPRPMPSISVAASSPIADQMLAQTPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEIEEQAKRESEGEDVLLQTYIKEQALQHAKMKQSQFSRSYLVTSTTNSNTNCSNSTSTTSSVSISCAVTTPIVNSKPQLNMAELPSIEVHEVKTPESPTPSPALVKSAEESEESETQSDQEKPSLTTPIPVPVTVSVSVAVPVSSTKSTAEIQQPHNANLPAAVQQPDATDFSGVLSSSSSNSNKNSNSSSGSSGSTAPTRIVVVGEDGFKTTPTSGSNELQSGGATAAATAAAPAGATYTNRVVPPPPPPIASDARPTCTVCNKTFQRTHQLSLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLSADAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPKRASSMSEDETLTNGLGLSHSHSHSHSLKRRLQNSSFSSNGDESDNPTDTTGSGSGSGSSEKRARSNTNEIITLPTPVAVSTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513682;
90% Identity: iTF_00499804;
80% Identity: -