Basic Information

Insect: Drosophila basisetae
Gene Symbol: PRDM1
Assembly: GCA_035041595.1
Location: JAWNLB010000174.1:1994601-1999222[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3.1e-05 0.0019 18.4 2.5 1 23 936 958 936 958 0.99

2 5 9.4e-06 0.00058 20.0 5.1 1 23 964 986 964 986 0.98

3 5 2e-06 0.00012 22.2 4.3 1 23 992 1014 992 1014 0.98

4 5 0.00066 0.04 14.2 2.4 1 23 1020 1042 1020 1042 0.97

5 5 0.00011 0.0068 16.7 0.1 1 22 1048 1069 1048 1069 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3.1e-05	0.0019	18.4	2.5	1	23	936	958	936	958	0.99
2	5	9.4e-06	0.00058	20.0	5.1	1	23	964	986	964	986	0.98
3	5	2e-06	0.00012	22.2	4.3	1	23	992	1014	992	1014	0.98
4	5	0.00066	0.04	14.2	2.4	1	23	1020	1042	1020	1042	0.97
5	5	0.00011	0.0068	16.7	0.1	1	22	1048	1069	1048	1069	0.96

Sequence Information

Coding Sequence: atgcatggacatcatcatcatcatcagcagcagcagcagcagcagcagcaaccactacagccgcagcaacaagtgcaacaaatgCCAGCCGCaatgaagcagcagcagcagcagctgcagcaacaacaaacacaacacatagccatacagcaacagcaacagcaccagcagcagcagcaacagcatcagcagcaaacgcatccgcatcatcatcatcatgcaaCAGCACAGCATCCACAACGGCATCCACAACAGCATCCACAACAGCACCCACATGCGCATCCACATCATCATGCAAAGCTGCTGCGTCGCTcgcgcagtcgcagtcgcagtccgACGCCGGATGGGACACAGGACTACGATGTGACGCGGATGCGTGAGGAGGACTTTGAGCGTTTAGCGGTATATTTGGTGCCCGACGTGCAAGCGGAGCGAGGGTTGCCCAATCGTGCGGATAAAACGCTGCCGCGCAGCCTAACGCTCAAGTCCTCCATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGCGTTATACCGCGTGGCACTCGCTTTGGCCCGTTCGAAGGCATTCCAACCTCAAATTATCCAAATGATAAGAATAAGGCGCGATATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGATTATTAAGATCTTCAAGgatgatgattattattatctggATGGCTCGGATCGCTCGGAATCCAATTGGATGCGCTATGTTGCCTCGGCGTATAGTTTGTCCGTTATGAATTTAGTGGCATGCCAGCATCAGGATAACATCTATTTCTACACCACCCGCGACATATTGCCCAACGAGGAGCTGATGGTCTGGTACTGCAAGGACTTTGCCAGCCGCCTCGGCTACGATGTGGACCCGGAGCGCACCATTTTCGGTGCCTGCAAAcaggatgtggatgtggatgaggatgaggacgaTGAACTGCCGCACAAGAAACCCCACTATGCAATGCCCGCTCCCGAAATACCCGCCGAGGTGGCTGTCAGTCATATTACCTATGTAATGGGATTGCATTTGCCCGGtgcaccacctccaccaccgcCACCCGCAGGATCAGTTGGAACAGCTGGTGCTCCATcggcagcaccagcacaaGCATCCGCCCAATGCTGTCGTCGCGGCAGCCCACCTGCCCATGTCAGCAccacaaccagcagcaacactaaCTCCAATTCCCTTCATCCGCATATACAGCACAGTCGGCACGCCTCGGTAATCATTGGCCAGGATCGGTCTCCCCTAAACAGTAGCTGTGAGAAGGAGACGGCTGGCTCACCGCTCTGTGGCAAGGATGCCCATTACGAGCATCAGTTGACGCCGCAGGATGGCAGCGTGCGATCGGTGCGCTCCGATGAAGGTTACCACAGCAACGAGTGCCAGGAGGATGGACTGACACCCCCCGAGGATTCCAGTGATAGCGAGAGTGAGCATAACTATGTGCTCGACTGCTCCAAGAAGGCAATTGCGCCCAAGGAGACGGTCATTGCGCAGGCGCAAAAGCCGAGCAGTGTATCATCACCACCGGCAGTagccaacaatagcaacagcaccaccagcaacagcaccaccaacagcagcgccaccaTCACGCCcaccgctgctgttgtcacgCCCAGTTGTGAGGCGGACAAGAACGAGTATCGTAAGTTCAAGGTAAAAATGCCActgaaatatgaatttaagaACAAGAGCTGTGTGAAAACGGAACCACTAAAGGAAGTGGATGAGCAACTGCCGCCAGTTGGTGTCGGtctggaggaggaggatctACACGAAATGCATGGTGCAGCGACGACGCATTGCGAGGATTCATTGTGCCCGCCCAGCACGACAACAACGCTGGGTGAGGAGCACCATCAGTTGCAGCATGTGATGGAGCCAACGAATCCACAGCCAGCCTCCTCCACGGTGATTGTGCTGGAGCACAGCTCCAATGGACAGACGCGAACCATTGTGCCGCTGAGTAAGCCCTACTACGAGGCCGATCCGCCCGTGGAGCGCTATGTGCGCTTCACACAGCCCAGCTCCAGCATCTTGGAGACGATACTCACCAGCCAGCATCGTTTGgaggcagctgccgctgcagcaaaTGCCTGTAGGCAGGCAAATGCGGCAACACCACCGCCCACATCGCCCACAGAGATGGCCTACAGCTATAAGAAATCACAGCGCTATGGCAATGCAGTGAGTCCCGATTCCAGCTCCAATCTGGGACAGCCGCAGGAGCTCACTAGTGCTCATGTGGTGCAGGAGCAGGAACTGAGTCTGAATCGTGGTGCATTGATCAAAGGCGAATGTTCGCCACCACCTCCATCctcgcatcatcatcataatgtGATCTATTCGCCGACGAGGGCGCATCACGGTGGCTACGAACCGGGCAGCCATTCACCCAGCTATACCGGCTATGCGGGCTATCCCGGGGCACAATCACTGCATGCTGCAACCTCAACGTTCCACTCACCACCCCACAGTTCGCACTCCCCCTTCGATCGCCAGTCGAATGCGTCTAGTGGCGGTGGCTCCGCTTCCAACTTGCATCTGTTGCAGAGCAGCACACAAATGTTGAACCATCCGTTGATGCAACCGCTGACGCCGTTGCAGCGTCTATCTCCGCTGCGCATCTCCCCACCCAGCAGTCTGAGTCCCGATGGCAACTCCTGTCCACGCAGCGGCAGTCCCTTGAGTCCCAACTCGTTGGCCTCTCGCGGCTACCGCTCGCTGCCGTATCCCCTGAAGAAGAAGGATGGCAAAATGCATTACGAGTGCAATGTTTGCTGCAAGACATTCGGCCAACTGAGCAATCTCAAAGTGCATCTGCGTACCCATTCCGGTGAGCGTCCGTTCAAGTGCAATGTGTGCACGAAGAGCTTCACACAGCTGGCGCATCTGCAGAAGCATCATCTGGTGCATACGGGTGAGAAGCCGCATCAGTGTGATATCTGCAAGAAGCGCTTCTCCAGCACATCCAATCTGAAGACGCATCTCCGGCTGCACAGCGGCCAGAAGCCCTACGCCTGCGATCTCTGTCCACAGAAATTTACACAATTCGTGCATTTGAAGTTGCACAAGCGTCTCCATACGAATGATCGACCGTATGTGTGCCAGGGCTGCGATAAGAAGTATATCAGTGCGTCTGGACTGCGCACACATTGGAAGACGACGAGCTGCAAGCCCAACAATCTGGAGGAGGAACTGGccatggcagcagcagcgacctCGGAATGTTTGGACAAAGATCTACCGGAGCCGGACTCGCGTGAGGCATATGAGCAGCTGCACCAGCACATGCATCCCGTGCATCCGAGTTTGCGTCATTTAGCTGGCACACAATCGCCGCCGCGTCTCATTCCGCTGGGCAGCAATGGACAGCcgcatatgcatatgcgaCAGCATTCACATCCGGCGCCGCCAGGACATTTAATGCACTCACCACATGGTGGTCCGCCCATGCTGCTGACCACAGCCAACCAGTTACCGCCACCAACAACGCCGCATcacatgcagcagcaacagcagcagcaacagcagcagcaacagcagcaacaacaacagcaacaaccttTGCCACAAGTCTCACCAggcagacagcaacagcagccgcagcattTGGGTGCAGCTCATCACTTAGCGCAGCATTCACCCAAATCGCTGAAGCCTTTGCCGGACACTGGCTATCTGCATGGGCCGCATGTCCAGGCGCAGGAGAATCGACCCTCGGTCATTGAGTCCTCCAGCCAGCCAATGATCATTGAGTGCACGTAG
Protein Sequence: MHGHHHHHQQQQQQQQQPLQPQQQVQQMPAAMKQQQQQLQQQQTQHIAIQQQQQHQQQQQQHQQQTHPHHHHHATAQHPQRHPQQHPQQHPHAHPHHHAKLLRRSRSRSRSPTPDGTQDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGIIKIFKDDDYYYLDGSDRSESNWMRYVASAYSLSVMNLVACQHQDNIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQDVDVDEDEDDELPHKKPHYAMPAPEIPAEVAVSHITYVMGLHLPGAPPPPPPPAGSVGTAGAPSAAPAQASAQCCRRGSPPAHVSTTTSSNTNSNSLHPHIQHSRHASVIIGQDRSPLNSSCEKETAGSPLCGKDAHYEHQLTPQDGSVRSVRSDEGYHSNECQEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSVSSPPAVANNSNSTTSNSTTNSSATITPTAAVVTPSCEADKNEYRKFKVKMPLKYEFKNKSCVKTEPLKEVDEQLPPVGVGLEEEDLHEMHGAATTHCEDSLCPPSTTTTLGEEHHQLQHVMEPTNPQPASSTVIVLEHSSNGQTRTIVPLSKPYYEADPPVERYVRFTQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQPQELTSAHVVQEQELSLNRGALIKGECSPPPPSSHHHHNVIYSPTRAHHGGYEPGSHSPSYTGYAGYPGAQSLHAATSTFHSPPHSSHSPFDRQSNASSGGGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPDSREAYEQLHQHMHPVHPSLRHLAGTQSPPRLIPLGSNGQPHMHMRQHSHPAPPGHLMHSPHGGPPMLLTTANQLPPPTTPHHMQQQQQQQQQQQQQQQQQQQPLPQVSPGRQQQQPQHLGAAHHLAQHSPKSLKPLPDTGYLHGPHVQAQENRPSVIESSSQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610151;
90% Identity: iTF_00498390;
80% Identity: -