Dbas005583.1
Basic Information
- Insect
- Drosophila basisetae
- Gene Symbol
- Znf48
- Assembly
- GCA_035041595.1
- Location
- JAWNLB010000116.1:8694853-8696898[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0034 0.21 12.0 2.0 3 23 12 32 11 32 0.95 2 11 0.0055 0.34 11.3 5.7 1 23 38 61 38 61 0.95 3 11 4e-06 0.00025 21.2 1.2 1 23 141 163 141 163 0.99 4 11 0.63 39 4.8 4.7 3 23 170 192 169 192 0.88 5 11 0.0037 0.23 11.9 4.2 1 23 199 222 199 222 0.97 6 11 5.5 3.3e+02 1.9 0.6 1 10 227 236 227 247 0.84 7 11 0.02 1.2 9.6 5.2 1 23 271 293 271 293 0.97 8 11 2.1e-05 0.0013 18.9 4.2 1 23 306 328 306 328 0.97 9 11 0.00012 0.0072 16.6 2.7 1 23 334 356 334 356 0.97 10 11 4.2e-06 0.00026 21.1 0.3 3 23 365 385 363 385 0.96 11 11 0.00039 0.024 14.9 1.2 1 22 391 412 391 415 0.91
Sequence Information
- Coding Sequence
- atgaaagctGTTGGAAAAAAGAATTCCAATATGTGCGAAACATGTGGCAAGTGCTTTTTAAAGCCTGCTCTGCTCCATCGCCATCTAGTTGTGCACAGTCCagcaaaattatttgcaTGCAACAGATGCTGCAGTCAATTCACACAGAAAAGTTCACTACGGCGCCACTTACGCACTAAGCATGATGAGGTCAATGACAGCGATTCTTCCCAGGTAGCGCAACAGGCTTTAGCTGCCTTAAAAGCACTGCAAGCCAGTCACCCAATTGTTGCTAACAAAGATGTACAAACTCCTCTCGAGGAACAGGAGCTAATCAGCTGTCAAGTGGTGCAGGTCAAGGATGCGCTCAATCCAAGGGGCGAGTTGCACTTGCTGCCTACGCAGCGCATACAGCGTCGCCAGGAGCGTGTTAGCTACTTTTATGTATGCGACTATTGCGCCAAGGAGTTTAGCAAGACCTACGATCTCATCCGACATCGTCGCTCGCACACCAAAGAGATGCCTtattgctgcattttttgcttgcatCGCTTTGCCACCCAGGCCAAGTTAAATGAGCATACGAAGAGGTTGCATGCCACCACGACAAAGAAGCACACATGCAGCGAGTGCAACGCTAGCTACAGTTTAAAAACCAAGCTGCACAAACATTTGGCGACACAACATCCGGATTCGGTTTACAGCTGTGCGCAGTGCAAGCGAATATTCCTCAGCCAAACAGCCTGCGAGGCACACGAGAAACTTGAAGCAGATGTGCAGGTGGCAAAACTGGTGCCGCTGTTGCCCCAGCCAGCGATTTCACAGCGCAGCTACAAATGCATCTATTGTGAGAAACAGTTCACGAGAAAATTCAACTGTCGCATCCATATGGTGACCCATCTAAAGCGTTTGCTGGTCACGCGTAGAATCCCAAAGCACAGCTGTCTGCAGTGTGGCAAGAATTTCACAAAGCTGCACGATCTGGAACGGCATCTGTTGACGCACTCCAAGCTCAAGATGCACATTTGTGGAGTGTGCCAGAAGCGCTTTACGCTCAAGCTAACATTAAACCGGCACCTGCAGACACATCAGGCAAAGCGCAATCGCATAAATTGTCAGGTGTGTGGCAAATCCTTTGCGTCCAGGACCTCCTTGCTGTTACATTTGCGGCTGCACACCGGCGAGCGGCCATTCAAGTGTGAAATTTGCCAAGAAACGTTTCGAACGTCAGGGCACAAGTTGGAGCATGTGCGAGGTGAACGGCACAGGAATGCCTCTGGCTACAATGCGCTTATATCTTGTAATGaggtttaa
- Protein Sequence
- MKAVGKKNSNMCETCGKCFLKPALLHRHLVVHSPAKLFACNRCCSQFTQKSSLRRHLRTKHDEVNDSDSSQVAQQALAALKALQASHPIVANKDVQTPLEEQELISCQVVQVKDALNPRGELHLLPTQRIQRRQERVSYFYVCDYCAKEFSKTYDLIRHRRSHTKEMPYCCIFCLHRFATQAKLNEHTKRLHATTTKKHTCSECNASYSLKTKLHKHLATQHPDSVYSCAQCKRIFLSQTACEAHEKLEADVQVAKLVPLLPQPAISQRSYKCIYCEKQFTRKFNCRIHMVTHLKRLLVTRRIPKHSCLQCGKNFTKLHDLERHLLTHSKLKMHICGVCQKRFTLKLTLNRHLQTHQAKRNRINCQVCGKSFASRTSLLLHLRLHTGERPFKCEICQETFRTSGHKLEHVRGERHRNASGYNALISCNEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00528231;
- 90% Identity
- iTF_00583140;
- 80% Identity
- -