Basic Information

Insect: Drosophila azteca
Gene Symbol: PRDM5
Assembly: GCA_005876895.1
Location: VCKU01000015.1:2551214-2554861[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0017 0.14 12.6 0.0 2 23 208 230 208 230 0.94

2 8 8.8 7.3e+02 0.9 1.2 2 21 792 813 792 815 0.87

3 8 1.3e-06 0.0001 22.4 2.8 1 23 885 907 885 907 0.98

4 8 0.00038 0.031 14.6 2.0 1 21 937 957 937 958 0.94

5 8 8.7e-07 7.1e-05 22.9 1.7 2 23 965 986 965 986 0.98

6 8 0.0076 0.63 10.5 1.1 1 23 992 1014 992 1014 0.98

7 8 0.0073 0.6 10.6 1.0 1 23 1020 1043 1020 1043 0.97

8 8 0.0034 0.28 11.6 0.2 1 23 1053 1075 1053 1075 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0017	0.14	12.6	0.0	2	23	208	230	208	230	0.94
2	8	8.8	7.3e+02	0.9	1.2	2	21	792	813	792	815	0.87
3	8	1.3e-06	0.0001	22.4	2.8	1	23	885	907	885	907	0.98
4	8	0.00038	0.031	14.6	2.0	1	21	937	957	937	958	0.94
5	8	8.7e-07	7.1e-05	22.9	1.7	2	23	965	986	965	986	0.98
6	8	0.0076	0.63	10.5	1.1	1	23	992	1014	992	1014	0.98
7	8	0.0073	0.6	10.6	1.0	1	23	1020	1043	1020	1043	0.97
8	8	0.0034	0.28	11.6	0.2	1	23	1053	1075	1053	1075	0.98

Sequence Information

Coding Sequence: ATGAACGATGCGGCTTTCTCGGGCTTCTACAGCGGCATTGGCAACCAGCTGCACCCGCCCCTCCCCCtacatcagcagcagcaacaacagagccagcaccagcaccaggaGCTGTCCCTGTCGACGCCCGTGCACGCCCTGGAGCCGGACACCAACTTCACAGGCTTCTTTGACGACGACATCGTGACCTGCGGCTCCACATCCTCCTCAGCCATCTGGCTGCCTATTCAGCTGGGCAACGGCAATCCCAATGGAGGTATCAATGGTCCAAACAAGGCAGCCGCCGAGGTTCCCTTTGTCCAGATCCACACCACGGACCTGCAACAGCAGGCGCAGCCGGAGAAGAGCTATCGCAATGCCTTTCGCCGCAGGACGGCGGAGATCAAGTCCGAGGAGCTGATCAAATCCGAGCTGGCCGAGGCTGCGGCCAAGGAACGCCTGAATGCCACGCCCACGCCACCCACACGCAATTCTAGCTGCGCCAGCGTCGAGGGCAAGGCCATGGTGCAGGAGGCGCCGATTCTCTTCAGGTGCCCCAACTGCCCGTTTCTCAGCCTCTGCCAGGTGAAGTCCAGCCAGCACGTAAACAACTGCTTCGGAACCAGCGCCGAGCAGCAGAGACAGTGTCCAGGCTGCCCGAACATCTTCTATAGCAGCGACGCCCTTAATGTGCATCTTAGCCTGGACCATCAGCTGGATGACGATGAGATTGTGACCCTGCTGGGTGGCACAGGCACACCCCCTAAAACGACCGGCAATAAGCAGCCTCTGCCCAAGAGCCGCATCTTCATCAAGAGCGTAGACTGTCTAAGGGAGCCCCTGCAGGATTTCCTACCTCTTCTGCAGCAGGAAACCGATTCTCCAGTCACTGGCAACATTCTTGATCTACTCGATGAAGTGGCAGAGACACCGGCACTGACATCCAGCACTGAGCAAGTGGCGCCGCCCTGCCAAAAGCCCAGCCAGAAGATATCCATCAAAAGCGTAGACGTGCTGAGGGAGCCTGCGCTGCTGACCTTCGATTTTCAGCTGCCCAATGGCTGCCAGGAGATGCCTCTGCTGGCGGACAGCAATCTGGATGTTTCAGTGGTGGGGGAGGAGGCGGAACCGGAGAAGCCGCGCCAACCCAAGATCTACATCAGAAACGTGGACATCCTCAAAGAGCCGATGTTGCTGCCCTCGTCCCTGCCCGGCATGGGCTTCAATGGAGGCGTTGCCACAACGATACCGATGCAGAATGGTGGTggcggaggaggagctgcCAACGATGTCTTCCAGGCGGATACGTTACTCACGCCAACGGGTCCGCTGCCAGGATTCGAGCCCAGCCTGGCGCCACTGGCCAACATGTGCTCCGAGCCCTTCCCCTTTGATTCCGTGCTAAGTGTGAGCGCAGGTGCAGGTGCCTCAACACTGGAAAACACCCGCTTCAGTGCCTTGGACTTGGACTTTGGCGTCGATTTTGACCATGGCATAGCGCCACTGCTCACAGAGGCCACACctccgccaccgccgccgccgccagtGCAGTCTGGCCTCTCGGAGCTGGAGCAGCCCGTCGAGCTGCAGCACTACCTGCCGACGGCTCCGAGCACCACGAAGCAAAAGATCTTCATCAAGAACGTAGACATCCTGAAGGCTCCCCAGCGGGGAACCCTCCACCTGCGCACCGTCGACGAGCTCAATTTTATGACCCGCAACGAGGTGGAGCGCCTGATAGTGCCCAATCTGGAACCGATGCCCAAAATGGAGCCCCTGAtggaccagcagcagcagcacacacagccacagtcgcagccgcagccgctgGATCCCCTGCAGCTAGAGCCGCAGAACTCTCAGACCCTTAGCGAGTTCCAGGCTCCTCTGAGCGGAAGCTGGCCAAGCGAGGACAGTTACGACCTCGCCGGGGATCTGGAGTGCTGGCCCTGGATCGAGGAGGCAGTGCAAGAGGTCATACCCCTACCGGATCCAAATGAAGCTGCCGCCGCAGCTGAAACACAAGTGGAGGCTCTTCCCCAGTCCTCGGACGATTTCCCCCAGCTGTATCCCTCACCGCCAGAAGCAGTACAAAGCGGCGGAGAAGCAGTGCCTCCCCTGGTGCCCGTCAGCGCCTCAGATGGCACTGCAGTCGCTTCTACAGGCTCCGGCCCGAGCAGTCTGCCCCTTCCTCCGCTGGTTCCTCTGGCGGCGGAGGCGGGCGAGAAGCCGGGACGCATCTATGTGGCCAACAATCTGCTGCCCGCCGCCGTGGATCCGCTGCCGGGTGGCACTTCGGTGCGCGGGCGTCCTTATGGAACCAAGCTGGCGTCAGGAAGCGGCGGAGGAAAACGAAAAGCAGCGCCGGGGATCAGCCAGGTGGCCGAGGGGGGTAAGTGCCAGGTAGAGGGCTGCATGTTCCGCTTCAAGTCGCCGGCGACGCTGGAGTATCATGGACGCTGCCACAACGACGTACTGGGGTCGTCCCAGCCCATGATCTGTCCGGAGTGCCGTTCGTCGGAGTTCAGCAACTGGAACTGCCTGCACACGCACCTGTGGCGCACTCACCAGATCGACATGGAGCTCTACTGCTGCCAGCTGTGCAGCTTCAAAACGCCCATCTACTCTCGGCTGGTCAACACCCACGCCAAGATCCACTCCGAGGAGCGCAACTACAAGTGCGAGCAGTGCGGCAAGGGATTCAAGAACACCAAGCAGCTGAAGAATCACAGACGGCTGCACCGCACCCAGGGACTGGGAATGGGCAAAGGTTCGCATCAAGATCAGGGCACAGCCGATGCTGatgctcctcctcctactgCCATCCTGCATCGCTGTGGCGACTGTGGGGCGGCCTTCAAGCAGCGCAAGACACTGCGCGAACATCTCTGCAAAGAGCGAAACGAACAGCCGCAGTGCTCCATCTGTCAGCGGGTTTTCAGCTCCAAGAGCAGCCTCAAACTGCACCTGCGCAGCCATCAGGCGAACAAGCGCTTCCAGTGCGATACCTGCGAGTACGAGGCGAGCGACCACAACGCCTTTCGACGCCATCTGGCCACGCATCGGGATCGCAAGCGCTACGCGTGTCCCCATTGCGACTTTCGGGCGATACAGAGCACTGCCTTTCGGATACACCTGCAGAAACGCCATCCGGAGAAGGAGCTCTCGTCCATCATCTACAAGTGCGATTTGTGCAGCTTCTCCAGCATCAATCAGGGTCTGTTGCTGGTTCATCAGGCCAAGCACGAGGCATCACCCAACCAACAGCCTCTCCCAGTGGTATTTCCTGTCTCCTTACATGTGGCACCTCCTGAGGCAGTTACAGCGGCAGTTGCTGTCCCCGAGGCAGGGGCAGTTCCAGCGACAGTTTCAACTCCATCACAAATCAAGGTGGAGACCAGCCTGCTGCTAGCTCATTCCAGTACAAATGTCGCCAAAAAGCAGGCGGTTGGTCCCTTGGCAGATATCCTACAGTCCTCCAAATCCTCCTAA
Protein Sequence: MNDAAFSGFYSGIGNQLHPPLPLHQQQQQQSQHQHQELSLSTPVHALEPDTNFTGFFDDDIVTCGSTSSSAIWLPIQLGNGNPNGGINGPNKAAAEVPFVQIHTTDLQQQAQPEKSYRNAFRRRTAEIKSEELIKSELAEAAAKERLNATPTPPTRNSSCASVEGKAMVQEAPILFRCPNCPFLSLCQVKSSQHVNNCFGTSAEQQRQCPGCPNIFYSSDALNVHLSLDHQLDDDEIVTLLGGTGTPPKTTGNKQPLPKSRIFIKSVDCLREPLQDFLPLLQQETDSPVTGNILDLLDEVAETPALTSSTEQVAPPCQKPSQKISIKSVDVLREPALLTFDFQLPNGCQEMPLLADSNLDVSVVGEEAEPEKPRQPKIYIRNVDILKEPMLLPSSLPGMGFNGGVATTIPMQNGGGGGGAANDVFQADTLLTPTGPLPGFEPSLAPLANMCSEPFPFDSVLSVSAGAGASTLENTRFSALDLDFGVDFDHGIAPLLTEATPPPPPPPPVQSGLSELEQPVELQHYLPTAPSTTKQKIFIKNVDILKAPQRGTLHLRTVDELNFMTRNEVERLIVPNLEPMPKMEPLMDQQQQHTQPQSQPQPLDPLQLEPQNSQTLSEFQAPLSGSWPSEDSYDLAGDLECWPWIEEAVQEVIPLPDPNEAAAAAETQVEALPQSSDDFPQLYPSPPEAVQSGGEAVPPLVPVSASDGTAVASTGSGPSSLPLPPLVPLAAEAGEKPGRIYVANNLLPAAVDPLPGGTSVRGRPYGTKLASGSGGGKRKAAPGISQVAEGGKCQVEGCMFRFKSPATLEYHGRCHNDVLGSSQPMICPECRSSEFSNWNCLHTHLWRTHQIDMELYCCQLCSFKTPIYSRLVNTHAKIHSEERNYKCEQCGKGFKNTKQLKNHRRLHRTQGLGMGKGSHQDQGTADADAPPPTAILHRCGDCGAAFKQRKTLREHLCKERNEQPQCSICQRVFSSKSSLKLHLRSHQANKRFQCDTCEYEASDHNAFRRHLATHRDRKRYACPHCDFRAIQSTAFRIHLQKRHPEKELSSIIYKCDLCSFSSINQGLLLVHQAKHEASPNQQPLPVVFPVSLHVAPPEAVTAAVAVPEAGAVPATVSTPSQIKVETSLLLAHSSTNVAKKQAVGPLADILQSSKSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00515212;
90% Identity: iTF_00481123;
80% Identity: -