Daus006868.1
Basic Information
- Insect
- Drosophila austrosaltans
- Gene Symbol
- zfh1
- Assembly
- GCA_035045865.1
- Location
- JAWNOQ010000049.1:2003505-2028992[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0029 0.33 12.2 1.9 2 23 72 94 71 94 0.95 2 9 0.003 0.34 12.2 0.1 1 23 292 314 292 314 0.97 3 9 3.3e-05 0.0037 18.3 1.8 2 23 328 349 327 349 0.97 4 9 5.7e-05 0.0065 17.6 6.3 1 23 358 380 358 380 0.99 5 9 0.00034 0.038 15.1 1.2 3 21 388 406 386 407 0.94 6 9 0.0019 0.21 12.8 0.5 2 21 663 682 662 683 0.92 7 9 8e-05 0.009 17.1 0.6 1 23 1054 1076 1054 1076 0.92 8 9 5.6e-05 0.0063 17.6 7.4 1 23 1082 1104 1082 1104 0.98 9 9 0.0028 0.32 12.2 4.3 1 21 1110 1130 1110 1131 0.96
Sequence Information
- Coding Sequence
- ATGTTGTCCTGTTTGGCGCCGTCGTCTTCACGTTTTGGCCAAGAGGATAACATTATACAGCAAAGCATGCCATCGTCCACAGCCTTCACCATGCAGTTTCCCTCTTTGGCCTCCAGTTTGCATCATCATCAGACACATAACAAATCGAATAATGCAGTCAGCAATACCGAGCATGTCCAACGTGGAGCAGGAGCTGTTGATGACTATTTGGTTAAATGTACACAGTGTCACAAGCGTTTCACAGAGTTTCAGTCCCTCAGTGAACATATTGCCAGCGAGCATCCCCATGACAAGCTTAATTTTGAGCCAAATCGGGGCACTGGCGCCGCACAACCTGAAAGCGATGCTGAAGATGAGCAAAGTAATTTGAGTAGCAGCAGTCGTCGCTATGCCAAATCTCCGGCAGttagtaacaacaacaataacaatagcgAATTGATCAAGAAtcacaataataacaataacaatagtGAAAAACATTCACCAATGTGCTCACCAGGATCTGGTGGTTCTCAGGGTCCAACAAGTGATCTATTTGCCCATCTAACACATGCCCCCCATCAATTGCCACCAAATTTGCATGCCCAATTTATGGCAGCAGCTGCATTGGCCATGCAATCGGCACGATCGGCCAGCACTTCAAGCTCACCgaatcatcatcttcatcatcaccagcagcaacagcatcaccaccaccaacaacaacaacagcaacagcagcagcagcatcaaggacaacagcagcaattattgccaccacaattgccgggTAGTAATAGTAGTGTTGGTAGCAATTCTGCATATGATTTGGATTTAAGTGCACCAAGATCAACATCCAGTCCAGGATCAACAACAGGTGATCTAAATGCTGCCTATCCATGCATGCAATGTGCGGCAGCATTTTCCACACGCGAACAATTGGAACAACATGAACTGATGCATTCGCCAAGTGGGCAACCAGTTACACAAAATATTACTCAGaCTTGCAAAATCTGTCACAAGGCCTTCGCAAATGTATACCGCCTGCAGCGTCATATGATCAGTCACGATGAGTCCGCCCTGTTGCGCAAATTCAAGTGTAGTCAATGCGAGAAGGCATTCAAATTTAAGCACCATCTGAAGGAGCACGTACGCATCCATTCCGGCGAGAAGCCCTTCGGCTGTGATAATTGCGGTAAACGTTTCTCTCACTCGGGCAGTTTCTCCTCCCACATGACATCGAAGAAGTGCATCAGCATGGGCCTGAAACTGAATAACAATCGTGCCATGCTAAAGACACTGGAAAAGGGCTCAGGATCGGGACGAGGTGGCTCTGGCGATCAGGGGCATCATCAGTCCGGCAAGCGTTCCAAACTTACTGAACAATCCACAACTATGGCCACGTTACCACCAGCATTACCAAATCCTATGATCTATTTTGCTGGCGATGCACCGAGTCAAAGTGCAGGCGCCAATGGACCAGCGGCTCCCTTCTATCCCAACTATGGGGCAATGAATGCAGCTCTCTTGGCATTTCCTTTTCTTGGGCCTCATCCGTATAGCATACAGAGGTTGTTGGAACTATCTGCAGCtggacagcagcaacaacaacaacagcagcagcagcatcatcaaaTGGAAGAAAGGGATGATCAGGTTGAGGATCATGACCATGAGCAGTTGGAAATCTACGAAGCAGCCAAAGATGAAGAAGAGACGCCAGATGAACCAAAATTGGTCATGGATTTAGATGAGAGTGCAACAGTCAAGGAACATGATGAGCCATTGGTTCAGCCAACTCAGAAGGAACAAGAGGAGGAAGAGACTATTGAAGTAAAGCAAGAAGCCAGTCGAGGAACAACTCCATTGCCAGAAAGTAATCCAACATCCCCCAAGACAATTAAGCAAGAGCAGGAAGAGGACAGATCGCCGGAGGAAGAGTCCACATTGGAGGTGGCAGGTGACAATAATGAACCAACCACATCCATGGAGACGCCTACTGAACTGCGTTGCAGTCGCTGTGATAAGCAATTTAATCATCCCACTGAGTTAGTTCAGCATGAAAAGGTTCTCTGTGGATTGATCAAAGAGGAACTGGAGCAACActatcagcaacaacaacagcaacagcaggcgTCGGTAAACTCCTTTGTCCTGCCTTCAGCCAGTGAAGATGAAGACGATCGGGATGTCGATGATGAACACGATCAGGAAACCAATACACGCCAGGATTTCAATGGCAGCGAAAATGGCGAAGCCGGACGAAAGGTTCGCGTCCGTACGGCCATCAAtgaagagcagcagcaacagcttaAACAACACTACGCTCACAATGCCCGTCCCAGTCGTGATGAGTTCCGCCTCATAGCTGCTCGTCTGCAACTTGATCCACGTGTTGTTCAGGTCTGGTTCCAGAACAATCGTTCGCGGGAACGCAAGATGCAAAGCTACAACACAAGCACCAATGTTGCAAACACTGAAAATGTGAGTGGTCCTTCAAGTCGTCCCTCTGGAGAGGATCAGCCGTTGGATTTGTCGGTAAAACGTGATTCCCTTTCACCAAAAGGCCAGCAATCGCCTCTCTATGGCCTGGCGCCACAGCAGGCTGCTGGTCAGCCAGCTTCTCTTGATTTCCAGGAAGCCATAAATCTTAGCCGTAAATTTGCCAGTTCGGCTTCCATGTCGCCAGCCTCGTTGTCTCCCTCATCGGGAGCATCTTTGcaccatcaacagcaacaacagcagcagcatcaatcCTCGGCAcaagcagctgcagctgctgcggCACTCTATTTTCGTGGTGCACCACCGTCGCCCCCATCCATGGAGGCCACGCCCATAGCACCATTACAATTGCCGCCCCAGAATTGTTCTAGAGCCCGGCAAAGTGGACATCCGTTTCCCGGACTACCGCCTTATATGTTACCCATGCAACAATTGCCCATGGAAGCGCTGTTCCAAATGCGTCCCGGCGAGTTTGCTCCCAATCCCCTAATGAACAGTATTAAAATGCCAGATTATCGTGGCACTAGCCTCAGTCCGGGTGGCTCCGAGAAACGTTCCTGGCGCGATGACGATTCACGCATCTCCCATGAGGATGACTATGGAGGCCTGTTGccaccaaaaccaaaacgagCCAAGGCCGAAACGCATGGACATGCCGGTGATGCAGATCTACCATTCTTATGCGATCAATGCGACAAAGCCTTTGCCAAGCAGAGTTCTCTGGCGCGCCACAAATACGAGCATTCCGGTCAACGACCCTACCAGTGTATGGACTgcccaaaggccttcaagcacAAGCATCATTTGACGGAGCACAAGCGTCTACATAGCGGTGAGAAGCCATTTCAGTGCTCCAAGTGCCTGAAACGCTTCTCGCATTCGGGCAGTTATAGCCAGCACATGAACCACCGTTACTCCTATTGCAAGCCCTACAGGGAATAG
- Protein Sequence
- MLSCLAPSSSRFGQEDNIIQQSMPSSTAFTMQFPSLASSLHHHQTHNKSNNAVSNTEHVQRGAGAVDDYLVKCTQCHKRFTEFQSLSEHIASEHPHDKLNFEPNRGTGAAQPESDAEDEQSNLSSSSRRYAKSPAVSNNNNNNSELIKNHNNNNNNSEKHSPMCSPGSGGSQGPTSDLFAHLTHAPHQLPPNLHAQFMAAAALAMQSARSASTSSSPNHHLHHHQQQQHHHHQQQQQQQQQQHQGQQQQLLPPQLPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLNAAYPCMQCAAAFSTREQLEQHELMHSPSGQPVTQNITQTCKICHKAFANVYRLQRHMISHDESALLRKFKCSQCEKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRAMLKTLEKGSGSGRGGSGDQGHHQSGKRSKLTEQSTTMATLPPALPNPMIYFAGDAPSQSAGANGPAAPFYPNYGAMNAALLAFPFLGPHPYSIQRLLELSAAGQQQQQQQQQQHHQMEERDDQVEDHDHEQLEIYEAAKDEEETPDEPKLVMDLDESATVKEHDEPLVQPTQKEQEEEETIEVKQEASRGTTPLPESNPTSPKTIKQEQEEDRSPEEESTLEVAGDNNEPTTSMETPTELRCSRCDKQFNHPTELVQHEKVLCGLIKEELEQHYQQQQQQQQASVNSFVLPSASEDEDDRDVDDEHDQETNTRQDFNGSENGEAGRKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRLIAARLQLDPRVVQVWFQNNRSRERKMQSYNTSTNVANTENVSGPSSRPSGEDQPLDLSVKRDSLSPKGQQSPLYGLAPQQAAGQPASLDFQEAINLSRKFASSASMSPASLSPSSGASLHHQQQQQQQHQSSAQAAAAAAALYFRGAPPSPPSMEATPIAPLQLPPQNCSRARQSGHPFPGLPPYMLPMQQLPMEALFQMRPGEFAPNPLMNSIKMPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYGGLLPPKPKRAKAETHGHAGDADLPFLCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00483587; iTF_00500944; iTF_00501283;
- 90% Identity
- iTF_00500944;
- 80% Identity
- iTF_00483587;