Basic Information

Insect: Drosophila austrosaltans
Gene Symbol: -
Assembly: GCA_035045865.1
Location: JAWNOQ010000211.1:4730716-4732097[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0038 0.43 11.8 3.7 1 23 136 158 136 158 0.97

2 9 0.00038 0.043 15.0 1.0 1 23 164 188 164 188 0.97

3 9 0.025 2.8 9.3 8.6 1 23 196 221 196 221 0.96

4 9 6.2e-05 0.007 17.5 1.6 1 23 230 252 230 252 0.95

5 9 3.3e-05 0.0038 18.3 0.4 1 23 260 284 260 284 0.95

6 9 0.00086 0.097 13.9 0.4 1 23 290 312 290 312 0.96

7 9 0.00025 0.029 15.5 3.0 1 23 318 341 318 341 0.98

8 9 8.2e-05 0.0093 17.1 0.8 1 23 347 369 347 369 0.98

9 9 3e-08 3.3e-06 27.9 0.2 1 23 375 397 375 397 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0038	0.43	11.8	3.7	1	23	136	158	136	158	0.97
2	9	0.00038	0.043	15.0	1.0	1	23	164	188	164	188	0.97
3	9	0.025	2.8	9.3	8.6	1	23	196	221	196	221	0.96
4	9	6.2e-05	0.007	17.5	1.6	1	23	230	252	230	252	0.95
5	9	3.3e-05	0.0038	18.3	0.4	1	23	260	284	260	284	0.95
6	9	0.00086	0.097	13.9	0.4	1	23	290	312	290	312	0.96
7	9	0.00025	0.029	15.5	3.0	1	23	318	341	318	341	0.98
8	9	8.2e-05	0.0093	17.1	0.8	1	23	347	369	347	369	0.98
9	9	3e-08	3.3e-06	27.9	0.2	1	23	375	397	375	397	0.98

Sequence Information

Coding Sequence: atgaggAAATGTCGCGGctgcttttgttttctgccCCAGACCAGCAAACGGTATAGTTTAATTGAAACACCGAAATTAGCAGAAAAATTCTATGCCTGTACCAGTATAAAAGTGGTCCATGACGAAGATGCTGAGACAGCGAAAGAAGGGGCGGAGCTTATGCCCAAAGAACTCTGTGAGGAATGTTTTGAGAAACTCGAAGAGTTTTATAGATTTCGCCAAATGTGCATAAAAGGGGATAAAAGATTTCACCAAGAGAAATTTCGTTTAGAGAATGAGActgaagaagaagaggaaagcGAAGATGAGATGGTGAAGGATAGACCACCCATAGAAGCCACAGAAATGGTTATGTGCGATGGACAGCAAGATGATATTACACCAACCAAATTGTCCCCTTTGCGCTTCAAATGTAGCATCTGCTCCAAACGTTTCTCTGTGGAGCATCGATTCTTGGCTCATTCACGTCAGCATAAGGGCCTAATGCCATATCCTTGCCCTGAAGCCAACTGCCAGCGTGGCTTTAATCGTCGCCAATGTCTGCAGGAGCACCTTAAAGAGCATGAGGGAAAAACGCTAAAGTGGTTTTATTGTGACCACGAGAATTGCCATAAAGCTTATCGCCATAAAGGCACTCTGGTTATGCACCTAAGAAGGTGTCATCAATTGGGTCCCGAACTGCAGTCACACATTTGTGAGTTTTGTGGAAGAGTCTTTAAATCGTTGACCTCACTCAACGATCatcgatatatacataaagataAGTCCGAGATGCCCTTTGCCTGCAAAGAGCCGGGTTGTTCACGCCGTTTCGCCACCAAAGAGAAACTCAAAGTGCACATAATGCGGCATTTGGGAGTCAAGAACTTTGCTTGTCCCTATTGCGGTTTGCGTAAGACTACCAGAAATGAACttaaaatccatatcaattatCATACATTGGAAAAGACATTTTCCTGCCGTTTTTGTTCTAAAATTTGTAACAGTTCTGGGAATCTTAAAATGCACGTACGTACCGTTCATGAGCGAGCCCGAGACTATCCCTGCAGTTATTGTGATAGGAGTTTTGCCAAACCGGATACACGAAAATATCATGAAATGACGCACACAGGCGAGAAAAACTTTGAATGCGAGGAGTGCGGCAAGCGATTCACTCAACCAGCAGCGTTGCGCACTCACCGCAGGATACATCAGCGGAAACAagaggctgctgctgctgccgctgccgttgcTACTACTGCAGCTCCTGCCACTGTTACAGCCACTGCCACAACCACTGTTACTGTCACTGGTATTGCATTTGGTCCTGTGTATTGTGTTCAAGTATAA
Protein Sequence: MRKCRGCFCFLPQTSKRYSLIETPKLAEKFYACTSIKVVHDEDAETAKEGAELMPKELCEECFEKLEEFYRFRQMCIKGDKRFHQEKFRLENETEEEEESEDEMVKDRPPIEATEMVMCDGQQDDITPTKLSPLRFKCSICSKRFSVEHRFLAHSRQHKGLMPYPCPEANCQRGFNRRQCLQEHLKEHEGKTLKWFYCDHENCHKAYRHKGTLVMHLRRCHQLGPELQSHICEFCGRVFKSLTSLNDHRYIHKDKSEMPFACKEPGCSRRFATKEKLKVHIMRHLGVKNFACPYCGLRKTTRNELKIHINYHTLEKTFSCRFCSKICNSSGNLKMHVRTVHERARDYPCSYCDRSFAKPDTRKYHEMTHTGEKNFECEECGKRFTQPAALRTHRRIHQRKQEAAAAAAAVATTAAPATVTATATTTVTVTGIAFGPVYCVQV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00556025;
90% Identity: iTF_00591212;
80% Identity: iTF_00577967;