Basic Information

Insect: Drosophila auraria
Gene Symbol: -
Assembly: GCA_008042615.1
Location: VNJW01005300.1:5962-10047[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0042 0.42 11.4 0.7 3 23 248 269 246 269 0.95

2 10 0.011 1.1 10.1 4.6 2 23 391 413 391 413 0.91

3 10 0.0085 0.85 10.4 2.3 3 23 491 512 489 512 0.94

4 10 0.096 9.6 7.1 3.5 1 19 616 634 616 639 0.94

5 10 0.00017 0.017 15.8 0.2 2 23 751 773 750 773 0.96

6 10 0.00098 0.098 13.4 0.2 2 23 819 841 818 841 0.92

7 10 0.0082 0.82 10.5 3.6 2 23 896 918 895 918 0.96

8 10 0.08 8 7.4 4.2 2 23 932 954 931 954 0.92

9 10 0.0016 0.16 12.7 0.7 2 23 1023 1045 1023 1045 0.95

10 10 0.037 3.7 8.4 0.6 1 23 1145 1167 1145 1167 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0042	0.42	11.4	0.7	3	23	248	269	246	269	0.95
2	10	0.011	1.1	10.1	4.6	2	23	391	413	391	413	0.91
3	10	0.0085	0.85	10.4	2.3	3	23	491	512	489	512	0.94
4	10	0.096	9.6	7.1	3.5	1	19	616	634	616	639	0.94
5	10	0.00017	0.017	15.8	0.2	2	23	751	773	750	773	0.96
6	10	0.00098	0.098	13.4	0.2	2	23	819	841	818	841	0.92
7	10	0.0082	0.82	10.5	3.6	2	23	896	918	895	918	0.96
8	10	0.08	8	7.4	4.2	2	23	932	954	931	954	0.92
9	10	0.0016	0.16	12.7	0.7	2	23	1023	1045	1023	1045	0.95
10	10	0.037	3.7	8.4	0.6	1	23	1145	1167	1145	1167	0.99

Sequence Information

Coding Sequence: ATGGCTGCATCCATATATGCCACCCCACCGCCAGATCTGAGCAGCGAGGACACTGCCCTCTCCGACGTCTCCAACTCATCGACACTGAACACGAaccgcaacagcaacagcaacaacacacaTGAAGCCGCAGGAGCAGCATCCCgagaaacagcagcagcatcaggaggaggaggaggaggagcagagaCAGGAGCAGGGGGAGGAGCTGGAGTGGGAGCCATTTCACCCGTCGAGCACTTGGTCAACCCAATGGAGCTGAAACTGGAGCCACAGCCAGCGGGAAGCGGCACAACtgagccggagccagagccagaggaAGGGCACAAGGATGTGGAGGAAGCggtggaagaggaggaggaggtgggaGATGCCCACATGGCCACCATGGCGGCAGCCAtgcagctgcaactgctggAGGCCCTAAGCGATGCGGCCAAGAAGCGACGCAAGCAGCACAACCCCAGCCGCCTGGAGGCGCTCAACCTCAGCGGAGAAGCTTCGGGACAGAAGCGTGGTGACTCCACCGTGGACTACGAGGAGAAGCTGTCCAAGATGTTCCTCCCAAAGTCCATCGAGCAGCTGAAGGAGACCttcgagctgctgcagcagcacaagCAGGATGAGGAGCAGCCCGAAGTCGAGCACGAGCCCCAGGCCGAGccggaagcggaaacggaagccaTGGCAGACATATCAGAGCAAGCGAGCAAGGAGCGCGAGAATCCCTACCACACCTTCTGCAAGCAGTGCGGCGAGAACTTCGAGACCGAGTTCAAGCTGAGCCTGCACATGCTGCAGGACCACAACGAGGATCGGGCGGGCGACCAGGATCCCGCCGACTTCCTGGCCTCCATCAAGGTGAAGCTCGAGCGAGCCGAGAGCCCCAGTCCGGCGCAGCAGGATCACCacatgcagctgcagcagcaccaactGACCAATGGCCACGGAAAGGACCTGGAGCGCGAGCAGGAGCACTGGTTCCAGGCCATGcagcaggcccaggcccaTCATCCGCACGCTGGCCAAATGCCGCCGGCGTTTCCCTTTCCTCCGGAGGCCGCACTGGGAGTGGGTCCAGCTGGCTACCTGCCGCTGCTGGGAATGTCCGGGTTTCCGGGAGTCGACGGCCTGAACCGCCCACCGCTAAGGATCTTCAACCCCGAGGCCTACTGCGAGCTGTGCAACAAGGAGTTCTGCAACAAGTACTTCCTCAAGACGCACAAGGCCAACAAGCacggcatcttcgaccccgtCGGGGAGCCCAGCACCCCCAACACTTCCAgccaccacaacaacaacaataacaacaccaccagcagcaataacaacaccAGCGGTCATCCCAATCCCGGCATGAGTTCCATGAGCCAGATGTTTCAGCTACAGAGAGAAGCGGCTCAGATGGCCAAGCAGGAGCAGGTATCGGCaagcggaggaggagcctCCGCTCCCGTGGCCACGGTGCACTGTGACGTCTGCTCCAAGCGCTTCACCAACGTCTTCGCCATGCGCCGCCATCGGGCCAAGCAGCACGACTCACTGCCCTCCGCCCAGGATTCACCGAACTCCCAGACCCAGACACCAACGCAGTCACAGTCGCAATCCCTTCGCGGCAGTCCCAACGAGCCACAGCAGACCATAAAGCAGGAGCTGCATCAGGAACCGGAACAGCTTAAGCCGTATCAGTTGCCCGAGGGCTTCCGCGAGGACTTCACcctggagcaggaggagctgagCTTCGTGCCGCCACCCCGGAAGCTGCCGTCGCACCTACACCAGCAGGCTAAGGAGGCCAACTTCAGTCCGGACAAGCTGCGGCGCCTGGGCGTCCAGTTCCCGGAGTTCTACTGCGAACTGTGCCACCGGGAGTACGCCAACAGGTACTTCCTGCGCACCCACAAGTGGAAGCGACACGGCCTGTTCGTGCCACCGGAAGACGTGACACCGCAGCAACCCGGCAAGGACGAGGCCCAGATGAGCGGCTGGCCCTTCATGCCGCTCAACCTGATGCTGGCCAAGGCGGCCGCAGCCTCCATGGATCAGCAGGAGAAGGACCAAGAGCTAACGGAGGCGGAGGCCGATGCCGAGCAGCCCAACAAGCGGATCAAGCTGGAAGAGCAGGAGCCGACCCCGCCGGAGGGCTACGACGAGGAGAAGCTGAACGGGTCGGTGGTGGGACTGCAGAACCTCCAGAAGCTCCAGTCCATGTTGCAGCAGCTGAACGACATCAACGGGAAGCGTCCCTTGCCGTGCCACCTCTGCGGCAGGGAGCTGGAGAACCAGTATGCGCTGAGGGCTCACCTGATGACCGAGCACGCGGGCCAGATGCAGCTGCCCATGCCCATACCCATTCCCCTGCCCGACCAGCAGGCGCCCCATCCCATGGCCGGTTTGTATCATCCCCAGACTCCGCCGGGTCCCGGCGCTAGATCCTCGCCCATCGGCGACCTGCGCTGCCAGCAGTGCGATCGGGACTTCGCAACGGCCCAGGAATTCAAGCAACATATCGCCGAGGTGCACATGGGCGGCCGGAATGGCGGAGGACTCGGAGGCAGTCCCCTGCGCGAGGGCTTCTTCACGCCGGAGCGCCCGGTGGCGCCGCCAGCTGGGGCAGGAGGAGCCGCCCCAGCCGGAGCTCCGCCAGGCAATCGGCCGGCGTACACCATCACGCCCACCAGCAGCTACTGCGAGATCTGCAACAAGGAGCTGTGCAACAAGTACTTCATGAAGACGCACATGCAGCGGATGCACGGCATCGAGATCGAGAACGGAGCCCAGATCGGCGGCGTCGTGTGCAACATATGCAACAAGGAGCTCTGCAGCAAGTACTTCCTGCGGGTGCACAAGCACAACACGCACGGCATCATCGAGGAGGGTTCCCCGCTGCCGCAGCCCCGGGGTCAGAACGGGGTGAAGATGGAGGCAGCCgccgcggcagcagctgctgcggcatCACAGTCCCAATCGCAGCCAGCAGCTCAGCCGCAGGATCAGGAGATGAATGTCTCGCCGCCCACAGTGGAGGGCGGTTCCAGCTCCAGTTCATCTGGCGCCAATCACGAGGTGTGTCCGCTGTGCTCGCGCCAGTTCCGCAGCTTCAAGTGGCTGCGATCTCATCTGATGAACGAGCACGGATCCGCAGGAGTCGAACGCCTCCGGGAGATGGAGACCAGCCAGTCGGGCTCGGGACGCAGCAAGCCCAACAGTCCCACGCTCAAGATACCCAACGGCAGTGGCAACGGCAACCCCACTCCggcgggagcgggagctggaAGTGCCGCTCCCAATCTCGCCCAGGCCCTGCAGAACCTCAATGCCCAGCACCTCTTCGgccagatgcagcagcagcagcagcaacagcagatgTCCAAGATGCCGCCGCTTCCGCTGCCAGGGATGTTCGGCGAGCAGGCGGCCAGGTTCAAGGAGTACCAGTGCTCACTGTGTCCCTTCACCACGCCCTACTACGCCTTCCTCTTCATCCACGAGCGCTCCCATGCGCTGCTCAACAACGGAGGCGACGGCATGGACCTGCAGATGGAAACGCCGCCACCGCAGCCGGCTAGGAACCCGGGAAAGTCCCGCAGCAAGTCCAGCAAGGCGGCAGTGGTGCCACCTCCGGCAGATCCAGCGGATCTTTCTGTGGAGCCCACCAACCTCAGCACCTCTGCAGCCAAGATCACACCATCGGCCGGATCTCCGGCCAACTCCTCCCCCAAGGCAACCAGCTCAACTTCCCCCAAGATTCAACGCCGTCGATCCTCCTCGAAGCCACCGACCACGCCCAACGGCCTGGGCAGTAGTGGCAACAATGGAATCGGagccggaaacggaagtggTGGCCACCGCTCGGCAGCCACCTCGCCCTTCGAGGGCTGCGGCGAGCTGGCCAACGGCAGCGGCAAGCCGGCGAGCTACGCCCAGCCGGATCGGGCAGAGGAAGCATATCAGATGCAGGCCTTCCACCTGCAGCCCGCCGACGCCGACTCGGAGATGCAGTTCGCACCTGCCCTGGTCTACCTGCCGGTGCGGGTGCGGGCCTCGGAGTCGGCCACGCTCAGCTTCCGGCTCACACCGGCCTAA
Protein Sequence: MAASIYATPPPDLSSEDTALSDVSNSSTLNTNRNSNSNNTHEAAGAASRETAAASGGGGGGAETGAGGGAGVGAISPVEHLVNPMELKLEPQPAGSGTTEPEPEPEEGHKDVEEAVEEEEEVGDAHMATMAAAMQLQLLEALSDAAKKRRKQHNPSRLEALNLSGEASGQKRGDSTVDYEEKLSKMFLPKSIEQLKETFELLQQHKQDEEQPEVEHEPQAEPEAETEAMADISEQASKERENPYHTFCKQCGENFETEFKLSLHMLQDHNEDRAGDQDPADFLASIKVKLERAESPSPAQQDHHMQLQQHQLTNGHGKDLEREQEHWFQAMQQAQAHHPHAGQMPPAFPFPPEAALGVGPAGYLPLLGMSGFPGVDGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPVGEPSTPNTSSHHNNNNNNTTSSNNNTSGHPNPGMSSMSQMFQLQREAAQMAKQEQVSASGGGASAPVATVHCDVCSKRFTNVFAMRRHRAKQHDSLPSAQDSPNSQTQTPTQSQSQSLRGSPNEPQQTIKQELHQEPEQLKPYQLPEGFREDFTLEQEELSFVPPPRKLPSHLHQQAKEANFSPDKLRRLGVQFPEFYCELCHREYANRYFLRTHKWKRHGLFVPPEDVTPQQPGKDEAQMSGWPFMPLNLMLAKAAAASMDQQEKDQELTEAEADAEQPNKRIKLEEQEPTPPEGYDEEKLNGSVVGLQNLQKLQSMLQQLNDINGKRPLPCHLCGRELENQYALRAHLMTEHAGQMQLPMPIPIPLPDQQAPHPMAGLYHPQTPPGPGARSSPIGDLRCQQCDRDFATAQEFKQHIAEVHMGGRNGGGLGGSPLREGFFTPERPVAPPAGAGGAAPAGAPPGNRPAYTITPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEEGSPLPQPRGQNGVKMEAAAAAAAAAASQSQSQPAAQPQDQEMNVSPPTVEGGSSSSSSGANHEVCPLCSRQFRSFKWLRSHLMNEHGSAGVERLREMETSQSGSGRSKPNSPTLKIPNGSGNGNPTPAGAGAGSAAPNLAQALQNLNAQHLFGQMQQQQQQQQMSKMPPLPLPGMFGEQAARFKEYQCSLCPFTTPYYAFLFIHERSHALLNNGGDGMDLQMETPPPQPARNPGKSRSKSSKAAVVPPPADPADLSVEPTNLSTSAAKITPSAGSPANSSPKATSSTSPKIQRRRSSSKPPTTPNGLGSSGNNGIGAGNGSGGHRSAATSPFEGCGELANGSGKPASYAQPDRAEEAYQMQAFHLQPADADSEMQFAPALVYLPVRVRASESATLSFRLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00594085;
90% Identity: iTF_00533328;
80% Identity: -