Basic Information

Insect: Drosophila auraria
Gene Symbol: -
Assembly: GCA_008042615.1
Location: VNJW01006627.1:3333-5572[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.2e-06 0.00022 21.7 0.8 1 23 441 463 441 463 0.98

2 7 7.2e-05 0.0072 17.0 0.6 1 23 469 492 469 492 0.98

3 7 1.2 1.2e+02 3.7 0.6 1 19 498 516 498 521 0.75

4 7 1.5e-05 0.0015 19.1 0.8 1 23 544 566 544 566 0.98

5 7 4.8e-05 0.0048 17.5 0.6 1 23 572 594 572 594 0.98

6 7 0.00016 0.016 15.8 0.2 2 23 601 622 600 622 0.95

7 7 0.00024 0.024 15.3 2.2 1 22 628 649 628 652 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.2e-06	0.00022	21.7	0.8	1	23	441	463	441	463	0.98
2	7	7.2e-05	0.0072	17.0	0.6	1	23	469	492	469	492	0.98
3	7	1.2	1.2e+02	3.7	0.6	1	19	498	516	498	521	0.75
4	7	1.5e-05	0.0015	19.1	0.8	1	23	544	566	544	566	0.98
5	7	4.8e-05	0.0048	17.5	0.6	1	23	572	594	572	594	0.98
6	7	0.00016	0.016	15.8	0.2	2	23	601	622	600	622	0.95
7	7	0.00024	0.024	15.3	2.2	1	22	628	649	628	652	0.91

Sequence Information

Coding Sequence: ATGAGATGTTCCGTGCCCAACTGTAGAAATGCTTTTATATCCAGATCCAAGAGGGGCCCGggtcagcagcagccggtTTCCTTCTTCCAGTTCCCCAAGTCGCCGGACCTCTTCAATAGCTGGCTCTCGTTCTGCGGAGTGAGTTCAGCGGCAGCCCTAAAAGTAAAGAACCCCTGCATCTGCATCGAACACTTCAAAGACGAGGACATAGAGGGGTCCATCAAATTCGAAATGGGACTGGCTAAGAAGAGAACTTTGCGGACAGGTGCGGTTCCCTGCATAAACAAGGGCCAGGAAAGCCCCTCGACAACAGCACGGAAGGAGCGCTCAGAGCGGCGAAGGAACAAGAAACTGGTGGACGACATACTGTTAGAGGATGAAGCCAGGTCTAATGCTCAAGCGGAAGTGGTTCCCACGCCCAACTACGTTCGGTTCAGCACGGGAATCGCTTCGGCGCTTCCATTCGTCACTCCCACGCCGGCAGAAGATGAGTTATCCCCTATGTTCACGGAAGATGATCCGCTTTTGGCTGAGGCAAGGATGTATAAGGAGAGATGCCGCACGTGCTACAAGGACTTTGTTGTCGACTCCAGTGCCAAAGATCTCTTCGACCCGGCGAACACTGTGCTAATTTTTCACATCGAAGTCATAAGCGGAGTTTGGATCAGGAACATCGAAGGGGAACCCCAGCTCATGTGTCCAGCTTGTCAGTTGTCGCTTCAACAGGCGATCGAATTCCGGGAGATGTGCATAGACATTGAGCTGAAGCTCACCCAGCATAAGGCTGCATTTGAGGATGAACCCGATCTGGAGATAGTCAAGGAAGAGTCATCAATTGTTGATGTTATTTCGGACTCGGAGTATTCCAATGCCGAAGATTATCCATCAGAGGAACCTGTTGTGGACGAACCCCTCTCTAATACGGAGTCCACAATAGAGTCTGTGGCAGAATCGCCCGAGACGGTTTCACAAGATCCACTCAGTGTCTCTCTGGGAGCCCAGATTTTCAAGGATCTAATCAACCAATATACGGGAAGGTCTACAACAAAGAAAGAGGCGCCTGTGGCAAAGGCAACGCCTGTTGCAAAGGCACCGCCCCTTGTAATGCCGAAGCTTGTTCCAATAGGGGCGCCCCTTGCAAAGGCGACTTTCGTTGCAAAGGCAGCGCCCGTTGAAAAGGCAGCGCCCGTTGAAAAGGTGTCGCCCGAACCCAAAACTACTACGGCTCCCGAACCAAAACCGAAGAGAAGAGCCAACCCCAAAACCAACGAAGAGAGGAATCGTATTCGACGTGCCCGGATACGAGCCAGGCCAACGAATTTCGTGTGCGATCAGTGCGGCCAGGCCTTCCGCATGAATCACAATCTGCAAATTCACATCCTTCGGCACAGTCGCACCAAGAACTACAAGTGCACCGAATGCCCCATGACCTTTTACGATGCTTACATGCGCAACATTCACATACGGATCAAGCATCGCGGGGAGACACCCTTCAGCTGTCGATTCTGCCCGGAAACGTTTGCCTATGCGCAGATACGTCAGAAGCATGAAAAAGAGGTCCATGGAGCAGCACCCCGCCGTATTGTGAACCGTATCAATCCGCAGCCAATGCCCCGCACCAATATGCGTTACCATTGCAATCTCTGTCCCAAAAACTATGCTTCCAAGTACGCCCTGGCCTGGCACATCAAGTCGCACACGGATGCGGGCGCCTACAAGTGTCAGCAATGCGAAAAGAGCTACTCGGAGCCGGCGCGACTCAAGCGCCACGAGATGATCCACGACGAGAAGAGGCCGCTGCAGTGTGAAGTTTGCGGAAAAGGGTTCTACCAACTAACGAAGCTAAGAGAGCACGAGACCATCCACACCGGCGAGCGCCCCTATCGGTGCGAGATTTGCGATGTCCACTTCCGCTACAAGTACAACATGAAGGTCCATGCAAACAGTAAAATGCACCAGGAGAACGTCTTGAAAGCCGAGTCTAATCAATTTGTAGAAATGTAA
Protein Sequence: MRCSVPNCRNAFISRSKRGPGQQQPVSFFQFPKSPDLFNSWLSFCGVSSAAALKVKNPCICIEHFKDEDIEGSIKFEMGLAKKRTLRTGAVPCINKGQESPSTTARKERSERRRNKKLVDDILLEDEARSNAQAEVVPTPNYVRFSTGIASALPFVTPTPAEDELSPMFTEDDPLLAEARMYKERCRTCYKDFVVDSSAKDLFDPANTVLIFHIEVISGVWIRNIEGEPQLMCPACQLSLQQAIEFREMCIDIELKLTQHKAAFEDEPDLEIVKEESSIVDVISDSEYSNAEDYPSEEPVVDEPLSNTESTIESVAESPETVSQDPLSVSLGAQIFKDLINQYTGRSTTKKEAPVAKATPVAKAPPLVMPKLVPIGAPLAKATFVAKAAPVEKAAPVEKVSPEPKTTTAPEPKPKRRANPKTNEERNRIRRARIRARPTNFVCDQCGQAFRMNHNLQIHILRHSRTKNYKCTECPMTFYDAYMRNIHIRIKHRGETPFSCRFCPETFAYAQIRQKHEKEVHGAAPRRIVNRINPQPMPRTNMRYHCNLCPKNYASKYALAWHIKSHTDAGAYKCQQCEKSYSEPARLKRHEMIHDEKRPLQCEVCGKGFYQLTKLREHETIHTGERPYRCEICDVHFRYKYNMKVHANSKMHQENVLKAESNQFVEM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00483017; iTF_00590444; iTF_00590273; iTF_00606353; iTF_00606542; iTF_00480370; iTF_00480204; iTF_00609204; iTF_00609391; iTF_00531861; iTF_00531693; iTF_00571933; iTF_00572124;
90% Identity: iTF_00483017; iTF_00609204; iTF_00609391;
80% Identity: iTF_00483017;