Basic Information

Insect: Drosophila auraria
Gene Symbol: -
Assembly: GCA_008042615.1
Location: VNJW01008199.1:35970-39074[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.3 1.3e+02 3.5 3.6 1 23 172 195 172 195 0.95

2 9 1.3 1.3e+02 3.5 1.4 3 23 249 270 248 270 0.90

3 9 0.00019 0.019 15.7 5.2 1 23 663 685 663 685 0.97

4 9 0.0033 0.33 11.7 0.3 3 23 693 713 691 713 0.97

5 9 0.0012 0.12 13.1 0.8 1 23 719 741 719 741 0.98

6 9 4e-07 4e-05 24.1 0.5 1 23 747 769 747 769 0.99

7 9 6.6e-06 0.00066 20.2 0.6 1 23 775 797 775 797 0.99

8 9 2.4e-06 0.00024 21.6 0.6 2 23 804 825 803 825 0.97

9 9 0.0002 0.02 15.6 0.5 1 23 831 854 831 854 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.3	1.3e+02	3.5	3.6	1	23	172	195	172	195	0.95
2	9	1.3	1.3e+02	3.5	1.4	3	23	249	270	248	270	0.90
3	9	0.00019	0.019	15.7	5.2	1	23	663	685	663	685	0.97
4	9	0.0033	0.33	11.7	0.3	3	23	693	713	691	713	0.97
5	9	0.0012	0.12	13.1	0.8	1	23	719	741	719	741	0.98
6	9	4e-07	4e-05	24.1	0.5	1	23	747	769	747	769	0.99
7	9	6.6e-06	0.00066	20.2	0.6	1	23	775	797	775	797	0.99
8	9	2.4e-06	0.00024	21.6	0.6	2	23	804	825	803	825	0.97
9	9	0.0002	0.02	15.6	0.5	1	23	831	854	831	854	0.96

Sequence Information

Coding Sequence: ATGCTGAAAATGACAAATGCTGCTGGGCCGCTGCAAACGATGAAGAAAAACGccaacggcagcggcaacgacGACTCCGAGGAGtcggacatggacatggacgaGAGTGAAGATGAAAGCGAAGCAGAACCCGTGGACGATGTGGTGCTACAGATCGACAGCGAGGACGAGGCGGAGCTGGAGGCGCAGCGCATTCGCTTGGTGCgcgaggaagaggaagaggccaaggccaagaccaagatagcaacaacaacaaagcagGAGGAGAGAGAAGCGCAGGTCAGTAACGGTAAAGCGAACGGCGTGGTGAAGAGGGAGACGGAGGAGAAGGCAGCGATCGGAACAACGAAATCCGGAAAGGCGGCCACCAAACGCAAGGCACGCGGCAAATCCGGACGCCGGGCCTCCGAGAGTTCGCAGGCCTCCAGTGTCGGCTCCGTTGCGTCCAACGCCAGCGTTGCCGCCTTGGTGGCCGCCCAGGTGCTGGCCGACGAGAAGACGCGCGGCTTCATCTACAGCTGCACGGAGTGCAGCCACCACTACGCCGACCGGGTGATCCTCTCGCGGCACTTCCAGAAGGAGCATGCCGAAAAGCCAAAGCGCAAGCGGGGTCGGAGCAAGGTCGCCAATCACGAAGAGGATTCAGCTGCGGACCCTAGCCCTCTTAACCTCCGTCCAGAGGATCTGAGCCACCTCAAGCCCTGCGCTCAGCTGCTTATGCAAGGCGAATCCCTGCTGCAGCTGTGCCTCGCCTGCAACTCTCAGTTTGTGGACCAGCAGCACTTCCAGGAGCATCTCAGCCAGCAGCACGGTTACTtcaagctgctgctggtgcccaAGGAGGAGCCCAGCGATCTGCCGCCACTGGCCATGGTCACCATTCCGGGGGCTCTGGCCTTGGGCAAGACCAACcagcagcttcagcttccCATCCCGGCGCCAGAGACGCCGCCGCCCGAGCAGGATACGAATACGGCTACCAATGGCAATGTGGTGGCCTCTAACGATAAGGAGGGTCTCCATATGATAAGCGCCATGGTGGCGGAGATTGCGGCCGAGAGGGTCAAGAAGACCAGCAGTCCCAAGGTCAGCAAGATGATCATCAAGCTGCCAACGGCGACCACCAAAAGGGGCAGGAAACGCGCCAAGCCCGAGAAGGCGAAGGAACGGACGCATCCGGAAATTTCTGaaatgctgcagctgcaggcgCTGAAACCGGAGAGCGATCAACCGAAGCCGGAGCAGCCACAGCCAATGGAAATAGCTGATGGGGCACCGGAGGAGACAAAGCAGCCCGAACAGCAGCCGCTGGAGACAGCAGCAGAGGATCAGGAACCCATGGAAACAGCTAAGGAAGTTCCTCAGCAGCTCGAGAAAGCAGACAAGGAACAGAAAGTTGAGGAAAAATTAGAAGGTGATTCTCAGCGAACGGAGAAAATCGAAGAGGAACCTCAGCAGCCAGAGAAAATTGAAGGGGAGTCGCAGCTGCCAGAAGTCAAGGAGCCATTGCCTGAAAAGGTTGAGAATAGTCAGCAGCCAAAGGTAGTTGAGGAGCCTTTGCAACAGGAAAAAGTAAAGGAGTCTCACCAGCCAGAGAAATCCAATATAAAGGAGCAGGAGAAACCACAGGGAGCACTAGCAGGGGAGCAGCGGCAGTCACCAGAGCCAAATCTCAATCCATCCAAGCGCAAGCGCGGCCGCAAAGAGCGCAAGTCGCCAACGCCCATACCCGTCCCGTTGGAAGACAAAGAAATCAAGAAGGAGTCTGAGAGCACAGAGCGGCGCACGCGCAAGACCCGCAACATTGTGGACTACGTAGTGGATATTAAGGACGAagaggaggacgaggaaggGGAGGAGGCTGAGCTGGATGGTGATTCCTCGGCCACAGTTTCACCAAACAACAGCTCCACGGACGAAAGTTTCACCTCGATCAAGCGTGAATCGTCCGTGGAGTCGCAGCGCAATGGAACCGGAGGCGGCATACACACCTGTAATTTCTGCGGCAAGACGTTCAAGCGTTTCTCCCGGATGCAGGATCACCTGCGCCTCCATACCGGCGAGAAGCCCTACGGTTGCGGACAGTGCGGCAAGGCGTTCCGCTTGAAGATGCGCCTGGTTGAGCACCAGCTGCGCCATCGCACTGAGAAGGCCTACAAATGTGAGATCTGCTCGATGCCACTGGCCACCAAGCAGGATCTGTCGCTCCACTTGCGTCACCACAAGAACGACAAGCGCTACAAGTGCGACAAGTGCAACAAGGGATTCGTTCGCAGCTCCGATTTGTCCATCCACGTCCGAATTCACACGGGCGAAAAGCCCTACAGCTGTGACATCTGCAGCAAGGCGTTCCGGGCCCGTCAGAATCTCGTAGTCCATCGCCGCACGCATCTTGGCGACAAGCCCATTCAGTGCGAGCTGTGCGACAAGCGCTTCGCCCGAAAGATCGATATGCGGGTGCACATGCGCAGGCATACCGGGGAGAAGCCCTACAATTGTGACTCCTGCCAGCGCGGCTACTCCTCCCGAGTGAATCTGGCGCGTCACCAGGAGCGGGAGCACGGCAAGAAAGAGGAGAAGAGCTCTGGATCTGGATCGGCCAagactgagaaaaaaaagtcgGAAAAGAAGCCGGCGAAGGAGCAGGAGACACAACCGCAGCCCAAGGCCAAAGAGGCGCCGCGACGTCCGCGACGCGAGAAGCTGCAGCAGAAGATCGCGGCTCAGGAAAAACTACTGGACGATCTGAAGCGCAGCCTGGGTACATTGCCGGAAATACCCGACGAAGAGTCATCTCAGGTTAAGTTGGATGCCGGGAAACTGCCAGCAGATGCCGGAGCAGGGCATGCCCAAGTTCAAGTCACGGTGTCCATGCAAATGGAACCCGCTCCCAACCACGAAGACGATGAGGAGATCACGCCGGAGAAGGAGAACGCGCTGTCCAGCTCGACAGGGTCGGCGGCCGATGCAGCAGGTGGCAAGACAAAGGCGAATCGCAAGATCACCAGCTACTTCACAGTCGTGGGTCAGCAGGCGGAAATCTAA
Protein Sequence: MLKMTNAAGPLQTMKKNANGSGNDDSEESDMDMDESEDESEAEPVDDVVLQIDSEDEAELEAQRIRLVREEEEEAKAKTKIATTTKQEEREAQVSNGKANGVVKRETEEKAAIGTTKSGKAATKRKARGKSGRRASESSQASSVGSVASNASVAALVAAQVLADEKTRGFIYSCTECSHHYADRVILSRHFQKEHAEKPKRKRGRSKVANHEEDSAADPSPLNLRPEDLSHLKPCAQLLMQGESLLQLCLACNSQFVDQQHFQEHLSQQHGYFKLLLVPKEEPSDLPPLAMVTIPGALALGKTNQQLQLPIPAPETPPPEQDTNTATNGNVVASNDKEGLHMISAMVAEIAAERVKKTSSPKVSKMIIKLPTATTKRGRKRAKPEKAKERTHPEISEMLQLQALKPESDQPKPEQPQPMEIADGAPEETKQPEQQPLETAAEDQEPMETAKEVPQQLEKADKEQKVEEKLEGDSQRTEKIEEEPQQPEKIEGESQLPEVKEPLPEKVENSQQPKVVEEPLQQEKVKESHQPEKSNIKEQEKPQGALAGEQRQSPEPNLNPSKRKRGRKERKSPTPIPVPLEDKEIKKESESTERRTRKTRNIVDYVVDIKDEEEDEEGEEAELDGDSSATVSPNNSSTDESFTSIKRESSVESQRNGTGGGIHTCNFCGKTFKRFSRMQDHLRLHTGEKPYGCGQCGKAFRLKMRLVEHQLRHRTEKAYKCEICSMPLATKQDLSLHLRHHKNDKRYKCDKCNKGFVRSSDLSIHVRIHTGEKPYSCDICSKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKIDMRVHMRRHTGEKPYNCDSCQRGYSSRVNLARHQEREHGKKEEKSSGSGSAKTEKKKSEKKPAKEQETQPQPKAKEAPRRPRREKLQQKIAAQEKLLDDLKRSLGTLPEIPDEESSQVKLDAGKLPADAGAGHAQVQVTVSMQMEPAPNHEDDEEITPEKENALSSSTGSAADAAGGKTKANRKITSYFTVVGQQAEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00606528;
90% Identity: iTF_00531844;
80% Identity: -