Basic Information

Insect: Drosophila auraria
Gene Symbol: hang
Assembly: GCA_008042615.1
Location: VNJW01008200.1:69033-77110[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.25 25 5.8 1.0 3 23 366 387 365 387 0.93

2 19 0.81 81 4.2 3.1 3 22 492 511 490 511 0.89

3 19 0.00054 0.054 14.2 3.3 1 22 630 651 630 653 0.90

4 19 0.068 6.8 7.6 0.1 2 21 665 684 664 685 0.94

5 19 0.00063 0.063 14.0 0.2 2 23 815 837 814 837 0.95

6 19 0.0018 0.18 12.6 0.1 1 23 845 868 845 868 0.96

7 19 1.5e-05 0.0015 19.1 0.1 2 23 954 975 953 975 0.97

8 19 0.00026 0.026 15.2 2.9 2 23 1059 1081 1058 1081 0.97

9 19 0.02 2 9.2 0.2 2 23 1090 1112 1089 1112 0.95

10 19 0.00072 0.072 13.8 0.2 1 23 1125 1148 1125 1148 0.97

11 19 0.00011 0.011 16.3 1.1 1 23 1215 1237 1215 1237 0.99

12 19 0.0018 0.18 12.6 0.9 1 23 1245 1268 1245 1268 0.96

13 19 0.69 69 4.4 0.3 2 19 1276 1293 1276 1294 0.93

14 19 2.9e-05 0.0029 18.2 1.4 3 23 1390 1410 1389 1410 0.98

15 19 0.0045 0.45 11.3 0.1 1 23 1445 1467 1445 1467 0.97

16 19 0.00053 0.053 14.2 0.6 2 23 1553 1575 1552 1575 0.93

17 19 0.49 49 4.9 0.1 2 20 1595 1613 1594 1615 0.91

18 19 0.0059 0.59 10.9 0.4 3 23 1630 1650 1630 1650 0.98

19 19 9.2e-05 0.0092 16.6 2.1 1 23 1948 1970 1948 1970 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.25	25	5.8	1.0	3	23	366	387	365	387	0.93
2	19	0.81	81	4.2	3.1	3	22	492	511	490	511	0.89
3	19	0.00054	0.054	14.2	3.3	1	22	630	651	630	653	0.90
4	19	0.068	6.8	7.6	0.1	2	21	665	684	664	685	0.94
5	19	0.00063	0.063	14.0	0.2	2	23	815	837	814	837	0.95
6	19	0.0018	0.18	12.6	0.1	1	23	845	868	845	868	0.96
7	19	1.5e-05	0.0015	19.1	0.1	2	23	954	975	953	975	0.97
8	19	0.00026	0.026	15.2	2.9	2	23	1059	1081	1058	1081	0.97
9	19	0.02	2	9.2	0.2	2	23	1090	1112	1089	1112	0.95
10	19	0.00072	0.072	13.8	0.2	1	23	1125	1148	1125	1148	0.97
11	19	0.00011	0.011	16.3	1.1	1	23	1215	1237	1215	1237	0.99
12	19	0.0018	0.18	12.6	0.9	1	23	1245	1268	1245	1268	0.96
13	19	0.69	69	4.4	0.3	2	19	1276	1293	1276	1294	0.93
14	19	2.9e-05	0.0029	18.2	1.4	3	23	1390	1410	1389	1410	0.98
15	19	0.0045	0.45	11.3	0.1	1	23	1445	1467	1445	1467	0.97
16	19	0.00053	0.053	14.2	0.6	2	23	1553	1575	1552	1575	0.93
17	19	0.49	49	4.9	0.1	2	20	1595	1613	1594	1615	0.91
18	19	0.0059	0.59	10.9	0.4	3	23	1630	1650	1630	1650	0.98
19	19	9.2e-05	0.0092	16.6	2.1	1	23	1948	1970	1948	1970	0.98

Sequence Information

Coding Sequence: ATGATTTGCGCAGTCTTCTGTTTGATGGAGCGAGCGGGGGCTTCAGGGGCCGGGGGCAAGGTGGAAAGGTGGAAAGAGGAgATCACCTCGCAGGATCGCCTGTCGCTGCATATATGCCACGCCTGCATCAGCTACCTGAACTCGTGGCAGAGCTTCAAGAACCGCTGCCTCAGCTCGCAGACAAAGCAGCGCCAGTGGCTGGACACCAACAACAAGAGCAAGCTCTTCAACTATCTGGACCTGAACAGTACCGAGAACGGAGGAGGATCCTCCTTCgatcatcaccagcagcaccaccagcagcatcagcatccgcatccgcatccgccgCATCAACCGCAATCGGAGAATGAGCTCGACGCGGCGGAGAAGGcgacggcagcggcagcggccacAACGGCCGCCAACATATTGGACGGCATACCCTCGCTGAAGAAACGCAAATCCCTAACAGTCTATTACAAGCCCAAGGTGTACTTGCCATTGGATATATCGGTGCCACCGCTACCGCCGCTGCCTTCAGTGGCTCCCGGATCGAttacagctgctgctgctgctcctgcgccTGCTGCCGTTCCTGCTGCTGAACAGCCGCTGCTCTCGGGATTCTCCGGTTTGGGCGGTGGAATGGAGAGcttgtcgctgtcgctgccacTTGATTTCAGCCAAAGCTGCAGCAGCGTCCAACAGCCGGCCACGGCCACAGCTACGGCCACGTCCACAGCGACGTCCACGTCCCATCCAACGGGCATCGCGTCGTCGGCTACGGCCacctctggctctggctctgcatCCGTGTCCacggctacggctacggctCCGCTGCTCATGCCGCCGCTGCCAGCGTTGCCCATCAAAGATGAGCCCATTGACACGGACGACGACTACCAGATGAAGTCGATAGACGAGTCCGACGACATGGTCGACCCCACAATGTTCCTAGAGCGTTCCGAGCACGAGGGCGATATGCCCTTCATGGCCTCGGACTACGACTACACGGCCCAGCATGGCGTCAATGCCCATTCCGTGGCTGCCGGCCTGCCGCCGAATGCGGTGGCCAATGTGGCCGCCGCCGGGGATTCCAAGGTGGCCAGCTGCCGGGCCTGCAGCCTGCAGTTCTCCACGCGAGCCAACGCCCGTCGGCACGAGCGCAATCTGCACCCGAACCTGTTCCAGCTCTCCACAGACTCGCCGCACTGCACGCCAATTACGAAGCCAACGCCGGCACTGGCCGCCGCCCTGGAAATCCAGCGGGCGGCAGCCGCAGCGGCCAGCGAGGAGGCGCACCGTGCCGCGGGCGGAAGTATCTCAACCCAAAAGTACCGCCAGGTGGTGATGAACGCGTTCATCAAGTCCGAGGGCGGCGGCTACGACTACGACAACCCGGAGCAGTACCGGCCGCTGCTCAGCCACGACAAGGTGGAGTTCATCGAGCAGAACGAGGAGTTCCTGGAGCAGTACCAGACGATgacctgccgctgctgcagcaagTACTTCAGCACGTACAAGAACTTCATGGCGCACGTGCGCAAGAAGTATCCGCTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATCTCGCACCTCAAGAAGCGCAACTGCATCAATCTCTACAGGGTTGTGACTATGCTGCGCGCTAAAGGACTACCTCTGCTGCCTCTGTGCGTCACGGAagcggaggaggcggcggtcGACGATGCAGGAGCCTCAGCTGTGGCCCTGGCGGTGGCCGATGCCGGAGCAGGCCAATCCCTCGTCACAATGGCCAGTCCCACGGTGACCGTTGGCGGGGAGTTGGTTGGCTCTGCGGGCGGCAACCCCGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAACAAGCTGTACGAGTGCAAGCTCTGCCCGAAGGGCTTCCGCACCAAGCACGAGTTCCGCACCCACGTCTACGACAAGCACGCCGACGTGCAGCGCAAGGACAACAGCACGACGCAGTGCAGCTTCTGCGGCCTGGACTTTGCCGATCCCGTGGACCGGCGGCGGCACTACAACAACATGGACTGCATTGTGCGGCTGCGCTGCATGACGTGCGACGCCAAGCTAGAGACGCACCAGCGCTTCCTCGACCACGTCTACCAGGACCATCTGGGCggcgtgggcggcggcggtggcggggcCAGCAGTGATAACGCCTCCACGACGGGCAGCGGCCTGGCCCGGAGCAACAGCATGGAGCACTCGCCGGGCAAGCGAAGTCTGCTCGGTGCCCTGGGCATTGGCGTTGGCTCCTCCGCCGAGGAGTCGCGCAGCAGCAGTGTGGCGCCCACCCTCACATCCACACCCAAGCCGGCGGGCACATCAGCAGCCTCTGCATCCGCTTCGAGCTCGGCCAATCGGGATGCGGCCGCTCCTAAGTCCCAGTACTTTTCGCGAATGCCGCAGGTGTGCCCCATCTGCGGGCAGCAgtacaacaactacaacaacgtGCTGCGCCACATGGAGTCGAAGCATCCGAACAAGCTGCCCGAGACGTACAAGTGCGTGCGCTGCGGCCTGGGCTATCCGCGGATCTCTTACCTGCGGGAGCACATGATCAATGTGCATGGCGTGGACAAGAACCGGCACTCGGGCGGCTTCGAGTACATCGTGAACGCCGATGCCGTGAAGCTGGCGGACGGCAGCACGCCGAATGTCTACACGGGTCGCTACGACTACGTGATGAAGGACCTGATGTCGATAACAAATGGTGGGACCCTCGATGAAGACGACGAGGAGGCGGGCAGCGTGGCCAAGAAGATGCGCCTGgacgacagcagcaacaacagcagcctggtgggcgtggccagccagcagcagaaggagtGCCCCATCTGCAATGCGGTGTTCAGCAACAACATTGGCCTGTCTAACCACATGCGCTCCCACTACACAGCCTCCAATGCGGTGAACGCAGCTTTGGCGGCCGCCAATCGCATGACACCCAAGTCGCTGACCATCACAGCCACTCCGGCCGCGGAGGCCAGCCCAGAGGCGACAGGCCTGCTATCCGCATCGATGGCTTCGGCTCCGGCGACGCCCAATGTCCCGCCAGCGATGGCGGGTCAAACGCCCCAGGAGCAGGCCGTCTTCCGACGCAGCTTGGATCAGGCGGCCGACCGTCGCTTCCGGCGCATGCGATGCCGCATCTGCCAGCGGCGCTTCAGCTCGAAGAAGTCCTATCGCTACCACATGCTGACGGACCACCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTCTGCAACGCCGAGTTCGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGCAGGGCCATCAAGGACGAGATGATCATCAAGCAGTTCGAGTGCGAGGTCTGCTCGATTGTGTACAGCTCGGAgatggagctgcagcagcacaagCGCAGCGTCCACAAGCTGACCTCGGCCTCCGCTTCGGCCTCTGCTTCTGCCTCGGCCTCCGCCTCTACTTCCTCGAAGATGGAGGAAGACTCGCTGATGGAGGAGAGCAAGGCTGCAGTGGGGGTCGGTGAGCACGCTGATCTGTCCGCCAATGCGTCCAGTGCCTCCGCTtcgggcctgggcctgggagTGGGCACGCCGCTGTACTGGTACCAGTGCAAGTACTGCCCCTCCAACTTCAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAACGATTACTCCTGCAAGGATTGCGGCAACGTCTACAGCGGCCGCAAGAGTCTATGGGTTCATCGCTACAAGAAGCATCCCCAGGTGCCCGACCCGGCCGAGTGCTCGCTGTGCCGCAAGATCTTCTTCGACCGCCAGATGCTGGACAACCACACGCCCACCTGCAACCGCAAGCCCATCACCTCGACGGGtgcccaccagcagcaggagtcgcagctgcagcaacagcaggcggCGCTCCAGCGAGCTGTGTTCCGGCACAAGACtggcgacgacgaggacgaggaggacgatgaccagcagcagcagctgcagttggAAGAGGGGGCCCCGAACAGTGATGGCAATGGGCTGGCAACGGGAGCGGCGGCTTCGGGAAGTGCTGCCGCCGtggctcctccgccgccgcctgcccTGAAGATCCGCATACCCGAGGTGGCCTGCACTATATGCGGGGCACGCTTCACCGACCAGGAGCACTTCAGCAAGCACATCCAGAAGCACGAGCAGGAGCTGTACGTGGACAATCCGCTGGCGGCGATGTTCGACGATGGGCCAGCGGATGCCGGCCAGTTCCAGGTGGAGCGGCAGAACGAGAACGGGGAGTACGCGTGCGATCTGTGCGCGAAGACGTTCCCCCAGGTGATTGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAAGCGACACAGTTGACCAACAACAATCATActaccagcaacaacaacaacaacaacaacaacagcagcagcagcagctcgatgCTGCACCTCCGCGAGCTGCATGCAGTGGGCCTGATGcccaaccagcagcagcagcagcagcaacagcagcagcagcagcagagccaccacagcaactccagcagcagcaagtcgATGAAGCGGAAGCGTGAGCTCAAGTGCGAGTACTGCGCCTCCACCTtcatcagcaacaacaacctgCGCCGCCACATGTACGAGCTGCACAAGCACGAGGTAAGCAATCTCCCCGAGCCGCCGGTCATCCTGGTGGACGACCACCTGCAGTGCCGTCGCTGCCAGCTCAGCTTCGACACGAAGGAGCTGTGGATCGAGCACAAGCTGGCCGATGCCAAGGTGGTGCGTCCCTTCTGTCCCTTCCAGTGGGGCTGCGACCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTGATGAACCACATCAACAATCATCTCAAGGAGGAGGTCATTGTGCCGGTGGCCACCAAGGCGGCCATTGATCGTGAGGCGGCAGCGGTCGCAGCAGCGGATGCAGAGAAGGCGAAGGAGCTGACGGTAGAAAGGGAGGAGGCTCAGGACAGCAAGAACAAGGCggagggagcagcagcaaaggaAGAAGAAAGCGATGACCTGGACGAGGAGGATAGCTcgggcgaggaggaggaggaggaaagtTCAGGCACgggcgacgacgaggacgatgacTCCGACGATGATGAGGAGGAAGATGACGAGGGCGATGGCGGCGAAGGTGAAGACGAGGAGGGCGTGCAGCCCGGTCACCTCTtgccgcaacagcagcagccgcacaAAGTAACCCTTGGCCAGGACGACGATGATCTCGTCGAGGAGGTCATTAGCTCGGACGAAGGCGAGGTGGAAagcgatgacgacgacgacgacgaagacgACGTCGAGGAAGATGACGATgtggaggaggacgacgacgaagatgaggatgtggaggagccggagccagtGGCAGTCGCAGTGCCAGCGCAGCCGCTGAtgaatggcaatggcaagTCGAAGATGCCGCCCCTGATCATGGCCAGCTCCGAcgatgaagatgatgatggtgTGATGCCCATCGAGGACATTATTGAAGAGGAGTTCGACGATCCGGATGTGGACGATGCCATCGAGGAGGTGGATGACGATGATTTGGATGAGGAGGGGGAGGGAGATGATGTGGAGGAGGACGAGCCGAATGTGGTGTCGGCGGCCTCCTCGTCGGAGAGCGAGTCCACCTCGACGACCACCTCcaattcgcattcgcattcacaTTCCACGGGTGAGCGGCGTAAGAAGAAGAGGGCTGACGATCAGTTGAATGATCCCAGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTACTCCAGAGCCACATCAAAAGCCATTTCCTCAATGGGCCAAAGCTCACCGccgccccagcagcagcagcggcggcggcaggcagcgcgtcagcaacggcaacggccaAGACGAAGCCTGACTCCAAGTCGGCGTCGGCGCTGCTGaccgccaacaacaacaacaataacaacaataagagCAGCAAGactgtggcagcagctgcagctgccacaAACTGA
Protein Sequence: MICAVFCLMERAGASGAGGKVERWKEEITSQDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLDTNNKSKLFNYLDLNSTENGGGSSFDHHQQHHQQHQHPHPHPPHQPQSENELDAAEKATAAAAATTAANILDGIPSLKKRKSLTVYYKPKVYLPLDISVPPLPPLPSVAPGSITAAAAAPAPAAVPAAEQPLLSGFSGLGGGMESLSLSLPLDFSQSCSSVQQPATATATATSTATSTSHPTGIASSATATSGSGSASVSTATATAPLLMPPLPALPIKDEPIDTDDDYQMKSIDESDDMVDPTMFLERSEHEGDMPFMASDYDYTAQHGVNAHSVAAGLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPHCTPITKPTPALAAALEIQRAAAAAASEEAHRAAGGSISTQKYRQVVMNAFIKSEGGGYDYDNPEQYRPLLSHDKVEFIEQNEEFLEQYQTMTCRCCSKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVVTMLRAKGLPLLPLCVTEAEEAAVDDAGASAVALAVADAGAGQSLVTMASPTVTVGGELVGSAGGNPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNSTTQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGGGGASSDNASTTGSGLARSNSMEHSPGKRSLLGALGIGVGSSAEESRSSSVAPTLTSTPKPAGTSAASASASSSANRDAAAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDEDDEEAGSVAKKMRLDDSSNNSSLVGVASQQQKECPICNAVFSNNIGLSNHMRSHYTASNAVNAALAAANRMTPKSLTITATPAAEASPEATGLLSASMASAPATPNVPPAMAGQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSEMELQQHKRSVHKLTSASASASASASASASTSSKMEEDSLMEESKAAVGVGEHADLSANASSASASGLGLGVGTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKIFFDRQMLDNHTPTCNRKPITSTGAHQQQESQLQQQQAALQRAVFRHKTGDDEDEEDDDQQQQLQLEEGAPNSDGNGLATGAAASGSAAAVAPPPPPALKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATQLTNNNHTTSNNNNNNNNSSSSSSMLHLRELHAVGLMPNQQQQQQQQQQQQQSHHSNSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVILVDDHLQCRRCQLSFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVATKAAIDREAAAVAAADAEKAKELTVEREEAQDSKNKAEGAAAKEEESDDLDEEDSSGEEEEEESSGTGDDEDDDSDDDEEEDDEGDGGEGEDEEGVQPGHLLPQQQQPHKVTLGQDDDDLVEEVISSDEGEVESDDDDDDEDDVEEDDDVEEDDDEDEDVEEPEPVAVAVPAQPLMNGNGKSKMPPLIMASSDDEDDDGVMPIEDIIEEEFDDPDVDDAIEEVDDDDLDEEGEGDDVEEDEPNVVSAASSSESESTSTTTSNSHSHSHSTGERRKKKRADDQLNDPSFTCDLCQLCFDSQELLQSHIKSHFLNGPKLTAAPAAAAAAAGSASATATAKTKPDSKSASALLTANNNNNNNNKSSKTVAAAAAATN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00606476; iTF_00485279; iTF_00531808;
90% Identity: -
80% Identity: -