Basic Information

Insect: Drosophila atroscutellata
Gene Symbol: ci
Assembly: GCA_035041605.1
Location: JAWNLA010000099.1:342576-354562[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.031 1.9 9.0 2.0 3 23 492 515 490 515 0.94

2 5 0.094 6 7.5 0.2 1 23 523 550 523 550 0.84

3 5 0.00017 0.011 16.1 2.9 1 23 556 580 556 580 0.98

4 5 0.00031 0.019 15.3 0.4 1 23 586 611 586 611 0.97

5 5 4.8e-05 0.003 17.8 0.4 1 23 617 641 617 641 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.031	1.9	9.0	2.0	3	23	492	515	490	515	0.94
2	5	0.094	6	7.5	0.2	1	23	523	550	523	550	0.84
3	5	0.00017	0.011	16.1	2.9	1	23	556	580	556	580	0.98
4	5	0.00031	0.019	15.3	0.4	1	23	586	611	586	611	0.97
5	5	4.8e-05	0.003	17.8	0.4	1	23	617	641	617	641	0.95

Sequence Information

Coding Sequence: ATGGATGCTTACACATTACCCACTTACTTTCCACTCGCGTATACGGAACTGCAGTTTTTGGCATCCCGTCGTGCcgcggctgccgctgctgctgcctctgttaTGCCCAGTTCCGCCAGCGGTGGTCACACAACGGATGTAAGCAGTACTGTGCCCGTGCCCGGTTCACCCATTCCGTCAGGGATTGCGGATTCAACACCCGCCACCGCGAATATGGCGACAACAAATGGCACAAATGGTGCCACAAATCAGGCGCTGACCATTGGCAATCTTCCcgcccatcatcatcatcatcacgtCCACAGCCATAGCCACAATCACAGTCACAGCCATCAACATGATTTCCATCCGGCTTACAGAATTCCCAGCTATATGGAACAGTTTTATTCCTTACAGCGCAGCAGTCCCTCGGCTTCCTATCATGATCCGTATGCGACCTGTTCCCCAGCTTTTCATTTAGCCGGATTGGGGCTGGGTTCGGGGGAGTATTTGAGTGCACGTGGCATGGGTTCGCTGAGCGAGTTGCATCAtgctgcagtggcagcagccgcagcagctgcagctggttCGCTGGCCAGCACCGATTTCCATTTCAGTCTGGATGGGAACGGGAGGCTGAACAGTCCAAGACCAGGGGGGGCAGGGAGCAGCATGCGTGCCAGTGTGAGCCGGAAGAGAGCATTGTCCTCCTCGCCCTACTCCGACTCCTTTGATATCAATTCGATGATTCGATTCTCCCCCAATTCGCTGGCTGCCACCTTGATGAACGGGGGGTCGAGAGGCAGTAGTGCTGCTAGTGGTTCCTATGGCCATTTGGCCGCCAGTCCCATGGCCCATGCCCATTCGGCAATGGCGCCACatctgcaacagttgcaggcgCATTTGTTGCGTGCCAGTGCTGGACTCTTGCACCCGATGACGCCGCAacaggcagcggcagctgccacCTATTCGATGAGTCATGTGGCAAGTGCCGCAGCTCTGGGGCTGACAGATGTCGCCCTCAAGTCAAAAGACCTGGCGGTGGGTTTGGCCAACGTCAGCCAGGCCTCAACTCCAACCTCCACCTTGATCAGCACAGCTGGAGAGGAttcaacgacgacaacgacaacgaccaCGATCAACAACAAGGCAGTGGGAGGAACGAAGaaCTTCGAGGAAGGTGGTTGTTGCACGGAACGCCATCGATCCTCAGCCGTCAAGAATCAATCGTCGAAGCACCTGGAGCAGCCCTCGTCTACATCGGAGAGTGTTGTGGCCCAGATGGAGGCGGATAGTGCTTCGGCTAACAGGTTGGAGCGACGACAACGGAGCAAATCTTTGGTaggtcagcaacaacaacaactgcaacaacaacgcatcCACGATGAGATTAACAGCCAAGTGGAGCATTCAGGATTCAATGAATACGATTGCACCACAGCGGATACAACAGATATTAAGGATGAGCCCGGTGATTTCATAGAGACAAATTGCCATTGGCGCAATTGCCACGTGGAATTTATGACCCAAGATGAGCTAGTGAAGCACATCAACAACGATCACATCCAGAGCAACAAGAAGGCCTTCGTCTGCCGCTGGGAGGATTGTTCCCGGGGCGAAAAACCCTTCAAAGCACAATATATGCTTGTCGTCCACATGCGGCGGCACACGGGAGAGAAGCCCCACAAATGCACTTTTGAGGGCTGCTACAAGGCGTATTCTCGCCTGGAGAACTTGAAGACGCATTTGCGTTCGCATACGGGCGAAAAACCGTATACGTGCGAATACCCCGGCTGCAGCAAGGCATTTAGCAATGCCAGCGATCGTGCCAAACACCAGAATCGCACACACAGCAATGAGAAACCGTACATTTGCAAGGCACCTGGTTGCACGAAGCGCTACACGGATCCCAGTTCGCTACGAAAACACCTTTCGCAGCATCcgcagctgcaggagcagcataTTGATTCAAGTCCCACAAGTGTCTCCAGTCCCAGCATCAAATCCGAATCcgaaacgacaacaacacatggaggaggcggaggaggggGTATTATTGGTGGCAACTCAGCTTCCGATTGTTTGTTGCAACTCTATCGCCATCAAACGGATGATCACTGGCCATacgatgatgttgatgttgatgccgCCGATTTGCCAATTGTTTTAAGGGCCATGGTCAATGGACACGgccatgcagcagcaacagttgcagctgcaacagcaactgttgcaacaacaacaacaacaactgttgttgcgtcagccacagcaacagcaacagttgcagcaacggcaacggcaacagttgctgcctcAATTTGCCGCCAGCCTTTTCGTAGTCGCctccaaaccaaaaacaattccATGTTATCGAATATACCCGAAACTAATCGCGCCATTGGCATCATCGAACTGAATCAGCGCATTACGGAGCTCAAAATGGAACCGGGCACAACTACGGCGGATCCGCAATTGCGGCGGGATAGTCAAAATTCCAATGCAAGCACTTATTATTGCAGCATGCCAAGTCGCAGGAGCAGTCAATGTTCACAGCTCTCCTCGATTTCCACTATGAGACCGGGTACGGTTTATAATACGGGCGTAGCGACGCCATCACTCTATGATCCCATTTCGCCGGGCTGTTCCCGGCGTTCCAGTCAGCTCTCAAACGTTCAGGCAACAACTGGAAATGgtttacatttaaattcaatttccaattttaatACCAATTCCGGCTTTACTTTAACGGCAAATCGTAGTGGAAGTGGGACGGGAAATGTCACTGGAAATGGGACGGGAAATGGAAGTAGAACTGGATCGGGAAATATCACTGAAAATGGTCTTGAAATAGCGCCTGGAACTAGGCCTGGAAATGGGCTTGGTCTGGCGCCGGGAATGAGGCCCGGAAATGCCATAGGAAGTTCTTTTGGCATGGGGAATTTGAGTCTGCCCCCGCCGCCCTCCTCTCACCTCATAGCCAGTCACTTGCAGCGCTTAAATCCGCAACAGCATACACAAAATCCACAACAGCATCCACAGCCGCCTGGAACTGCTCGCTTTTCCAGTGGAATGTTGCAATTTCCAGCCAATTATTATCAAAATTCCCATAACGACTTGGAAACATTTCGACGCCAATCGGAACCAATCGCCTGCCGGAACCAGTTCCAAGCGCCACGCAATCGCAGCAgctccacaacaacaacagttccAGATCCAGTTCCAATATCAGTTCCAGctgcaaatttaaatcatCCTAATGAGCAAGTTGTGAATTTGGACGAAGTTGAGGAATTAATTTTGCCTGATGAAAtgttgcaatatttaaatctgGTCAAGGAAACGGAACAGCCCAAAACCAGGCCTGGCAAACAGGAACTGCTAAACTTAAAATCAAGTTCCACTAaaacatttacaacaacaaatgcaaatctttCTAAATTGCCGCCTCCCCTGGCCAGTCCCAGCCTGGAACTGTTATCGCCACAATCAACTCACACTATGTCAGCCCTGGGCAGCCCATACTCTCAACGGAACTATGAACTGGAAGCGAGTCACCAAAGTCATCGCTATCAGCCCGCAAATCTCTACAATCAGAATAATTATCAACACTCCGAAAATTTACACAATGCGCAACAAAATCAGGTCATTGATTCGTCAATGACAAGTTTGCCGGAATTGGTTCCGACGCTGCCCAAAATGAACCAAAGTGAGCAGCTCAGCTGTGCAGCGGCTGAAATTCAATGTGGCGTCGTCAGCCAATCACAGCTTTCGCCCACTGCTGCGCCAGCTAACGGCCAGAatgcgcaacagcagcagcagcagcaacaacatcagcagcagcagcaacaacagcagcaacaacagcagcaacaacaacagcagcaacaacagcagctacaacaacagcagcaacaacagctgcagcaacaacagcagacatCTATGCAATCGGATACATATCAGCGAACGCTGGAATATGTGCAGAGCTGTCAGAACTGGAtggagagcaacagcaacaataacagcagcaataacagcaacaataacagtctGTCAGCTCATGCGCAAATGGCTGTCAACAGAACAgtaacagtagcagcagctgcagcagtacaaaacaataatatttggcCGGATGTGAGCAGCTCaacgcatccacatccacatccggGCGGCAATATGATTATCAATGATATGACAACTTCATTAAGCTCGCTGCTCGAAGAGAATCGATACTTGCAAATGATGCAGTAA
Protein Sequence: MDAYTLPTYFPLAYTELQFLASRRAAAAAAAASVMPSSASGGHTTDVSSTVPVPGSPIPSGIADSTPATANMATTNGTNGATNQALTIGNLPAHHHHHHVHSHSHNHSHSHQHDFHPAYRIPSYMEQFYSLQRSSPSASYHDPYATCSPAFHLAGLGLGSGEYLSARGMGSLSELHHAAVAAAAAAAAGSLASTDFHFSLDGNGRLNSPRPGGAGSSMRASVSRKRALSSSPYSDSFDINSMIRFSPNSLAATLMNGGSRGSSAASGSYGHLAASPMAHAHSAMAPHLQQLQAHLLRASAGLLHPMTPQQAAAAATYSMSHVASAAALGLTDVALKSKDLAVGLANVSQASTPTSTLISTAGEDSTTTTTTTTINNKAVGGTKNFEEGGCCTERHRSSAVKNQSSKHLEQPSSTSESVVAQMEADSASANRLERRQRSKSLVGQQQQQLQQQRIHDEINSQVEHSGFNEYDCTTADTTDIKDEPGDFIETNCHWRNCHVEFMTQDELVKHINNDHIQSNKKAFVCRWEDCSRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCYKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHLSQHPQLQEQHIDSSPTSVSSPSIKSESETTTTHGGGGGGGIIGGNSASDCLLQLYRHQTDDHWPYDDVDVDAADLPIVLRAMVNGHGHAAATVAAATATVATTTTTTVVASATATATVAATATATVAASICRQPFRSRLQTKNNSMLSNIPETNRAIGIIELNQRITELKMEPGTTTADPQLRRDSQNSNASTYYCSMPSRRSSQCSQLSSISTMRPGTVYNTGVATPSLYDPISPGCSRRSSQLSNVQATTGNGLHLNSISNFNTNSGFTLTANRSGSGTGNVTGNGTGNGSRTGSGNITENGLEIAPGTRPGNGLGLAPGMRPGNAIGSSFGMGNLSLPPPPSSHLIASHLQRLNPQQHTQNPQQHPQPPGTARFSSGMLQFPANYYQNSHNDLETFRRQSEPIACRNQFQAPRNRSSSTTTTVPDPVPISVPAANLNHPNEQVVNLDEVEELILPDEMLQYLNLVKETEQPKTRPGKQELLNLKSSSTKTFTTTNANLSKLPPPLASPSLELLSPQSTHTMSALGSPYSQRNYELEASHQSHRYQPANLYNQNNYQHSENLHNAQQNQVIDSSMTSLPELVPTLPKMNQSEQLSCAAAEIQCGVVSQSQLSPTAAPANGQNAQQQQQQQQHQQQQQQQQQQQQQQQQQQQQQLQQQQQQQLQQQQQTSMQSDTYQRTLEYVQSCQNWMESNSNNNSSNNSNNNSLSAHAQMAVNRTVTVAAAAAVQNNNIWPDVSSSTHPHPHPGGNMIINDMTTSLSSLLEENRYLQMMQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517279;
90% Identity: iTF_00521732;
80% Identity: -