Basic Information

Insect: Drosophila atroscutellata
Gene Symbol: -
Assembly: GCA_035041605.1
Location: JAWNLA010000094.1:3224258-3228778[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.00052 0.033 14.6 0.9 1 23 208 230 208 230 0.97

2 25 0.00061 0.039 14.3 2.8 2 23 237 258 236 258 0.97

3 25 0.016 1 9.9 0.8 2 23 289 310 288 310 0.96

4 25 0.0064 0.41 11.1 2.4 1 23 385 408 385 408 0.94

5 25 3 1.9e+02 2.8 0.4 1 20 447 466 447 468 0.91

6 25 1 64 4.2 0.6 2 23 494 515 493 515 0.96

7 25 0.012 0.75 10.3 0.7 1 23 589 612 589 612 0.96

8 25 0.0088 0.56 10.7 0.1 1 22 621 642 621 642 0.95

9 25 0.0031 0.2 12.1 4.3 1 23 651 674 651 674 0.97

10 25 6.4e-05 0.0041 17.4 0.4 2 23 688 709 687 709 0.97

11 25 2.1e-05 0.0013 19.0 5.4 1 23 715 737 715 737 0.98

12 25 0.14 8.8 6.9 1.3 1 23 876 899 876 899 0.95

13 25 0.028 1.8 9.1 2.2 1 22 906 927 906 927 0.95

14 25 0.4 26 5.5 0.4 1 20 936 955 936 959 0.86

15 25 5.8e-05 0.0037 17.6 1.6 1 23 983 1005 983 1005 0.97

16 25 0.00044 0.028 14.8 0.7 1 23 1012 1034 1012 1034 0.98

17 25 0.12 7.7 7.1 0.0 2 21 1061 1080 1060 1081 0.94

18 25 0.039 2.5 8.7 4.0 1 23 1126 1149 1126 1149 0.96

19 25 0.0066 0.42 11.1 1.5 1 23 1186 1209 1186 1209 0.96

20 25 0.014 0.9 10.1 3.1 1 23 1236 1259 1236 1259 0.97

21 25 1.3e-05 0.00085 19.6 0.1 2 23 1280 1301 1279 1301 0.95

22 25 4.6e-05 0.0029 17.9 2.9 1 23 1307 1329 1307 1329 0.99

23 25 4.1e-06 0.00026 21.2 2.3 1 23 1335 1357 1335 1357 0.97

24 25 2.8e-07 1.8e-05 24.8 2.6 1 23 1363 1385 1363 1385 0.99

25 25 0.00049 0.031 14.6 0.3 1 22 1391 1412 1391 1415 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.00052	0.033	14.6	0.9	1	23	208	230	208	230	0.97
2	25	0.00061	0.039	14.3	2.8	2	23	237	258	236	258	0.97
3	25	0.016	1	9.9	0.8	2	23	289	310	288	310	0.96
4	25	0.0064	0.41	11.1	2.4	1	23	385	408	385	408	0.94
5	25	3	1.9e+02	2.8	0.4	1	20	447	466	447	468	0.91
6	25	1	64	4.2	0.6	2	23	494	515	493	515	0.96
7	25	0.012	0.75	10.3	0.7	1	23	589	612	589	612	0.96
8	25	0.0088	0.56	10.7	0.1	1	22	621	642	621	642	0.95
9	25	0.0031	0.2	12.1	4.3	1	23	651	674	651	674	0.97
10	25	6.4e-05	0.0041	17.4	0.4	2	23	688	709	687	709	0.97
11	25	2.1e-05	0.0013	19.0	5.4	1	23	715	737	715	737	0.98
12	25	0.14	8.8	6.9	1.3	1	23	876	899	876	899	0.95
13	25	0.028	1.8	9.1	2.2	1	22	906	927	906	927	0.95
14	25	0.4	26	5.5	0.4	1	20	936	955	936	959	0.86
15	25	5.8e-05	0.0037	17.6	1.6	1	23	983	1005	983	1005	0.97
16	25	0.00044	0.028	14.8	0.7	1	23	1012	1034	1012	1034	0.98
17	25	0.12	7.7	7.1	0.0	2	21	1061	1080	1060	1081	0.94
18	25	0.039	2.5	8.7	4.0	1	23	1126	1149	1126	1149	0.96
19	25	0.0066	0.42	11.1	1.5	1	23	1186	1209	1186	1209	0.96
20	25	0.014	0.9	10.1	3.1	1	23	1236	1259	1236	1259	0.97
21	25	1.3e-05	0.00085	19.6	0.1	2	23	1280	1301	1279	1301	0.95
22	25	4.6e-05	0.0029	17.9	2.9	1	23	1307	1329	1307	1329	0.99
23	25	4.1e-06	0.00026	21.2	2.3	1	23	1335	1357	1335	1357	0.97
24	25	2.8e-07	1.8e-05	24.8	2.6	1	23	1363	1385	1363	1385	0.99
25	25	0.00049	0.031	14.6	0.3	1	22	1391	1412	1391	1415	0.91

Sequence Information

Coding Sequence: atgttgcCGACGAATGTTTGTCGCACGTGTGCGCTACAAGATGACAACTTGTTTGCGCTGGCAACGCGTAGTGAGAAATACGCAAAGAAAAGTATCTGCGAAATGCTGCACGAATTAACACAAAACGATCCACTGCTGGAGCATACAGATGATAAGCTACCGCAGCATTTGTGCGGCCAATGCTTGAGCCAGCTGGAAGCAGCTTATGCATTTGTGCTGCAAGCCCGCGAGGCGCaggagcaactgttgctgcagctacGCAAAGGATTGCAGACACAGTGCCTGGACGAAACACCTATCGATATAAGCATAGAACACATCAAAATCGAAACAGACATTGACCTAGTTGATGCTGAGTTTGAGGAGGAGCGGGAGAAGCAGGTTGTCTTAAAATGTCAACCGGAAACTGATAGCGATAGCAGTCAGGATAATGTGAAGGACCATGACGTTGAGGTCCAAACCCTGCAGCTGCGGCGCAGTGCTCGGCGAGCCAATCTGAGCACTGACAGCGAAAATGAGTCAATcagctccgagcagctgcagccgttGCCTGTTAAACGTGGACGCGGTCGTCCCCGACGTGTGGCCAAGAGGGCGACAACCACCAACGAGGATGGGCGGCATGTGTGCGAGGTGTGCGGCAAGACCTTCTCCTGGTATCGCGATATGCAGCGCCATGCACGCATCCACTTCGAGCAGGCGGGCATTGTGTGCGAGCACTGCGGCAAGAAGTTCCTGCGCAAGGACAAGTACATGACCCATCTGCGATCACACACAAAGCACGTGGCCACAGACAGACTGCCACGGAGCAGCGAATGGCGCTACGCGGAGCGTCTATACAGCTCCGGCAGATTAATGCGTGTGGAGTGCAAACTGTGCGGCATGAGTTGCCAGCGCATTCGGGAGTTGCGCGACCACCTGGCGAGTCATGTTCACATTGAGACATTGTGGAATCTCAGCCTGGATAACGATGTCATTCGGGAACAGTTTGGCAGCCAATCGGATTTGCAGCAAATCAAGGAACAGGTCTGCACGCAAATTGCCAAAGGTCGTGAACAACTGGAGAATTACGGCGCCGTGGTGAATGCCTACGGTTATGAGCTGTGCCTCAGCGACtcggatgaggaggaggatgaggagctgCCTGGCAAATATCAGTGTCTGCGCTGCAATGTCAACTTTGCACGCAAGCATCAATTCGTGCGACATACGCTCGAGGAGCACATGGACAGAAGTGAAACCCCTTTGGAACGCTGCAATATTTGTCAAATTGGCTTTCTTTGCGCCaagctgctggagcagcatcAGCGCACGCAGTGCCTCAATCCGCTGAAGCGTTACAGCTGCGAGAATTGTCCTGGCAAGTTTATTTGGCTGCAGAACCTGCAGCAGCATGCATGCAGCAGGCTGCAACATGATCTGCAGCAGGAACTGCAGCACCGGCatcaggagcagcagcaggcacctCATCGCCAGATCCAGTGTTGCCTGTGCAATGAACGACCCAGCAGCATGGCTGCCCTACGCTCTCATTTACTCACTCATCGCGATGGACACACGGACATCGATCCGCATCAGCAGTCTGCCTTCTTTCGCACCTATTACCAGGATGACGGCGTCAGCAGCCTGTCGGAGATTAGAGCACGCATCGCTGGCGACTTTGAGGCGCAGCTTTATGGAAGATATTTCAATGCGTGTACGGACAGCGGACAGGAACTGGACTTTAACGACTCCGACATGGAGTGGAGCGATGCGCCCGCTCTACATAGCTGTGCCGTGTGTGGCGAGAGTAGAATCCGCCTCAATCAGCTGCTCCAGCATCAGCAGAGCCAGCACATTGAGCTGGCAGACAGACTGCCTCACGTCTGCTCAGATTGTGGATTGGGCTATGTGGCCgagtcgctgctgcagcagcatcgtcgTCGCATATGCGCCAAGCTGCATGCCAAGTACCAGTGTCCACACTGCAGTCAGCGGTTCTATTGGCACTCTAACTACGAGCGGCACATTCAGGTGCAACATCCTGCGGAGAGGCAGCAGGGGCAGGAAAAGAGCAAGCTTCAGTGCAGCGAGTGTGATAAGGTGTTCATCTGGCCTAAGGATTTGACGCGCCACAAGCGCATGCATCAGTCGCAGGTGCAGTTCGAATGCGTCCACTGCGATCGCAAGTTCCATCGCAAGGATGGCCTAAAGTCGCACATGCGGATGCACGGCGAGCTGCTGACGTCGTCTCTCggtgagcagctgcagcgcatGCCGATGGTCTTGAGCCAGCTGTGTCGCCCCAATGGCTGCAAGCAGATCAAGTGCATGATTTGCCTGTCGCAGCACACGAAGATCTCCGATTTGCGAACGCATTTGACTAGCCATCAGTTGAGACTGTGTTTGGCCGAGGAGCGAGGCATCGCAAACATTTGTCGTGCTCTCTATCCGGAGCTGAACACGCCATTGAATCAGCAGGCATTGATCAAGCGCATCCAGCGGGATCTGGGCAatgaactggagctggagagATTCGTTTCGATAACAAATGAGGCGGGCATCGAACTAAGCCTGGACAGCAGCGAAACCGACACGGATTCGGATTGTGCAGCAGAAACCGAACGGAGCTGCATGGAACGCGGTTACAGCTGTGAACTGTGCCAGGTGCAGGTGATGCGCAAACATCAGCTCTATGCCCACCAGCTGGAGAAGCACATGTGGCACCAGACGACGCACGTCTGCAGCCACTGCCAGGCGAGATTCGTGaatgagcagctgctggaCCATCACTATCGCACTCTCTGCCGCAATGCCCAGCGGCGTTTTCTGTGTCGCAAGTGTCCGTTGCGTTTTCGATGGCGCGATAATCTCAAGCTGCACAATGGTGTGGCGCATCAGGAGCGAGGGAATGTGGAACAGCACTCCAATGTGGACATTCAGTTGAGTATGCTGCCCGTGGTTAGCTATGACTGTGTCGAGTGCAAGCGTAgcttcaaaatgcaaaaggatCTAACACGGCACACCTTGATGCATGCCCAGGAGTCGAGCATCTATCGGTGTCGCTGGTGCGCTCGACGCTTCTATCGAGAGGCGAATCTGCTGCAGCACATCGAGCGCCATGGCATCAGCGCCGACCAGCTGCCTTATGCTGAGGCCCTGCTCAACGCCAGTCGTCATCCGCACGGCCCGAAGTGCATAAAGTGTCGCGTGTGTGAATTATCCTTTGGCAGCATTGCGGCACTGCGCTCGCATCTGCAATCGTCGCCAGTTGGCACTCATCATCCGATTGAATCCATGGCCAACTATTCGATCACCAATCAGCTGGGTTACGAGCTGCATCTGGACGACTCAGAAACTGATGAGGAAGCCAAGCCGGCGGGCACCCCGGCGCATTATACGTGCGGCATGTGCCAGCTGCGTTGTGTGCGCAAGTTTGagctgcatcagcatcagcaggccATGCATCGTCTGGAGCGCATTGCCGATGGCTGCGATCTGTGCATCTTCAAGAGCGTCTCGCCCGACCTTATTGCCTATCATCGGCGTGTGCTGTGCGAGAACACAGAGAAGCAGTTCAAGTGCTCTAAATGCAGCTACAAGTTTATGTGGCAATCGAATCTGGTGCAGCACATCCAACTGCAGCATCCCAGCAGCGAGGAGTCGACTACAAAAACATCAATGCCCATGGCTGTGCCCGACATTGCCAACGCCGAGTGCCACATCTTCCAATGTGGTCAGTGTCCCAGTAAATACAATCGCAAGGATCGCCTCACCGCCCATGTAAAAAAGTGTCACACAGCTGGCTCAACTGCATCAACAAAAGCGCCAGCGGTTGCCAAGCAGCAAAAGAGTTTCCTGTGCGCATTCTGCGGCAAGGCGGTGAGCTCATCCTCCAATTTAATCATACACATACGTCGGCATACCGGCGAAAAGCCGTTTAAGTGTGATTACTGCGACATGGCTTTTCCGCGCTCCTCTGATCTCCAGTGCCATCGACGCACTCACACCGGCGAACGGCCACACATCTGCACCGTCTGCAAGAAGGGATTTGCTCGCTCCtacaagctgcagcagcacatgcGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTCACACTCCACATCCGGCGCCACACGGGCGAGCGACCTTATCAGTGCAATACGTGCGGCGAGCGATTCATTCAGGGCACAGCGCTCAAGAACCATCGAATGCAGAATGGCCACTATGAGACGGAAGTGGGTCAATCGAAAGTTGACTAA
Protein Sequence: MLPTNVCRTCALQDDNLFALATRSEKYAKKSICEMLHELTQNDPLLEHTDDKLPQHLCGQCLSQLEAAYAFVLQAREAQEQLLLQLRKGLQTQCLDETPIDISIEHIKIETDIDLVDAEFEEEREKQVVLKCQPETDSDSSQDNVKDHDVEVQTLQLRRSARRANLSTDSENESISSEQLQPLPVKRGRGRPRRVAKRATTTNEDGRHVCEVCGKTFSWYRDMQRHARIHFEQAGIVCEHCGKKFLRKDKYMTHLRSHTKHVATDRLPRSSEWRYAERLYSSGRLMRVECKLCGMSCQRIRELRDHLASHVHIETLWNLSLDNDVIREQFGSQSDLQQIKEQVCTQIAKGREQLENYGAVVNAYGYELCLSDSDEEEDEELPGKYQCLRCNVNFARKHQFVRHTLEEHMDRSETPLERCNICQIGFLCAKLLEQHQRTQCLNPLKRYSCENCPGKFIWLQNLQQHACSRLQHDLQQELQHRHQEQQQAPHRQIQCCLCNERPSSMAALRSHLLTHRDGHTDIDPHQQSAFFRTYYQDDGVSSLSEIRARIAGDFEAQLYGRYFNACTDSGQELDFNDSDMEWSDAPALHSCAVCGESRIRLNQLLQHQQSQHIELADRLPHVCSDCGLGYVAESLLQQHRRRICAKLHAKYQCPHCSQRFYWHSNYERHIQVQHPAERQQGQEKSKLQCSECDKVFIWPKDLTRHKRMHQSQVQFECVHCDRKFHRKDGLKSHMRMHGELLTSSLGEQLQRMPMVLSQLCRPNGCKQIKCMICLSQHTKISDLRTHLTSHQLRLCLAEERGIANICRALYPELNTPLNQQALIKRIQRDLGNELELERFVSITNEAGIELSLDSSETDTDSDCAAETERSCMERGYSCELCQVQVMRKHQLYAHQLEKHMWHQTTHVCSHCQARFVNEQLLDHHYRTLCRNAQRRFLCRKCPLRFRWRDNLKLHNGVAHQERGNVEQHSNVDIQLSMLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYREANLLQHIERHGISADQLPYAEALLNASRHPHGPKCIKCRVCELSFGSIAALRSHLQSSPVGTHHPIESMANYSITNQLGYELHLDDSETDEEAKPAGTPAHYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCDLCIFKSVSPDLIAYHRRVLCENTEKQFKCSKCSYKFMWQSNLVQHIQLQHPSSEESTTKTSMPMAVPDIANAECHIFQCGQCPSKYNRKDRLTAHVKKCHTAGSTASTKAPAVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRMQNGHYETEVGQSKVD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00610043;
80% Identity: -