Basic Information

Insect: Drosophila atripex
Gene Symbol: gfi1b
Assembly: GCA_035045925.1
Location: JAWNOP010000052.1:16235355-16237278[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0037 0.28 11.7 1.4 2 23 410 432 409 432 0.95

2 6 0.0002 0.016 15.7 1.0 1 23 439 462 439 462 0.95

3 6 1.3e-05 0.001 19.4 1.0 2 23 468 489 467 489 0.96

4 6 0.00018 0.014 15.8 1.0 1 23 495 518 495 518 0.91

5 6 6.2e-05 0.0048 17.3 6.3 1 23 524 546 524 546 0.97

6 6 2.5e-05 0.002 18.5 1.1 2 23 553 574 552 574 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0037	0.28	11.7	1.4	2	23	410	432	409	432	0.95
2	6	0.0002	0.016	15.7	1.0	1	23	439	462	439	462	0.95
3	6	1.3e-05	0.001	19.4	1.0	2	23	468	489	467	489	0.96
4	6	0.00018	0.014	15.8	1.0	1	23	495	518	495	518	0.91
5	6	6.2e-05	0.0048	17.3	6.3	1	23	524	546	524	546	0.97
6	6	2.5e-05	0.002	18.5	1.1	2	23	553	574	552	574	0.97

Sequence Information

Coding Sequence: atggaAGTGTGTGGCAGCGTGCTGGTGAATTCGAATTACCAGCAGTTCCGGCTGAAATGCATATACTGCACCACAGAAAGCGAGCTCCATGATTGGAAGCTGTTCATCAACCATGTGCGGACATCACATTATTGCGAGGAAGATGAGGCCTCTGCCTCCATAGATGTCCCAACCAAAGAAAACACTGATGGATTAGACCCCGAAATCGAATACGAACCAGAAGAATTATACGATATCATTGAAACGGTTGAGGAAGATGACCAATGGttgaaaaatggaaatggcatgGAAGAGGACAGTCAATATGCGGAGAATAAGGGGACTTACTGTGAATACCTCCCTGAATCCAATGAAGCGCCAGATCCATCAGAAGGTGATGCATCCAGCTGCCACTATGACACGTCTTCTTTGAAAACAGAACCTTTAGTGGAGTACGAAAGTGGTAGCGAATATAATTCAGATAGGGAAGAACCACCGCAACCACGGCGTCCCGGACGGCCACCAAAACGTACCAGACCCGATCAGGTGTTTAAGTTCAAAGTGTCGTTTATACGAAGCAATCCCCGTGTGCTTCATCTGATCCAGGTGTATAGGGAACACCCTTGTCTATGGAATCCAGCAGATGATTTTTATGAGGACGAGGCCGTGCGGAAGCAGGCGTACCAATCGATAATAAGTCGCATGGAGCTGAAAACCGACGTACTTTTGACTGTGGCCGAGTTGAAGCGAACTCTGGTGCAGCTGCACACGCAATACGCCCTTGCCGGAGAGATGAAAGCGAAAGGGAAGCTGGTCGGACTCGCATCTCGTTACTATGCCAAATGCGAATTCCTCAGCGTGTCCCCGCCCGTAAAAGTAAGGCAGATCGAAGAGGACACTAACCTAATCACAATTAAGcTTGATTTTAAGGAGGATAACTTAGTGACTAGTTCTTTTATAGAGACATATGCCAACTATCCGATGTTATACAATCCATCACACCCAGATTTCTGTTCGATAGATGCGAGAGCCGAAGCCTATGTAAAGCTGGCGGATGAGTTCCAGCCAGTCGTGAAGGCTAATGAAACGGACGTTTACATAGCCGTAAATAAGCTGAGGCGTTGGGCTTATGAGGCTATGAGGCGGCTCAAAGCCAAAGAGCTGATTGAATCTTGCAATAAGCAGGAGGTGCAGTACTTGCGTATGTGTAGCTTTTTACCCGCCAAAGGTTCGGAAAGTGCTGTGTTGTACTGCGATGTCTGCAGCAGGCGGTTTCACGGCGACTACAACCTGCGTGTCCATATGTTCAAAGCCCATATGTTGGGCGAGCTACCTTATCTTTGTTCTATGTGCCCGCGGCGCTTTGACAGACAAGTGGACATGGAACGGCACAAACAACGATCGCATTTCGCCAACCGGCTGAAGTGCGAATATTGCGATAAAACCTTTGCTGTCTACCACGACTTAAAGGTACACACTCTTATCCACACCGGCGAGAAGCCGCATGTGTGCGaagtttgtggcaaatcgttCCGTCTGAAACTGCTTTTGGATCATCACATAAACGGCGTCCACCTCAACATTCGGCCTCACACCTGCCACTTGTGCAACAAAAGTTTCCGCAAAAAGTTCGAGCTGTCCAATCACATTAAAGGACACTATAATATTCGTGATAAAAAATGCGAGGTGTGCGGAGCCGCTTTTTACGATCATTCTTCCCTCTCCAGACATCGCCGAGGCCATagagaaaaacaataa
Protein Sequence: MEVCGSVLVNSNYQQFRLKCIYCTTESELHDWKLFINHVRTSHYCEEDEASASIDVPTKENTDGLDPEIEYEPEELYDIIETVEEDDQWLKNGNGMEEDSQYAENKGTYCEYLPESNEAPDPSEGDASSCHYDTSSLKTEPLVEYESGSEYNSDREEPPQPRRPGRPPKRTRPDQVFKFKVSFIRSNPRVLHLIQVYREHPCLWNPADDFYEDEAVRKQAYQSIISRMELKTDVLLTVAELKRTLVQLHTQYALAGEMKAKGKLVGLASRYYAKCEFLSVSPPVKVRQIEEDTNLITIKLDFKEDNLVTSSFIETYANYPMLYNPSHPDFCSIDARAEAYVKLADEFQPVVKANETDVYIAVNKLRRWAYEAMRRLKAKELIESCNKQEVQYLRMCSFLPAKGSESAVLYCDVCSRRFHGDYNLRVHMFKAHMLGELPYLCSMCPRRFDRQVDMERHKQRSHFANRLKCEYCDKTFAVYHDLKVHTLIHTGEKPHVCEVCGKSFRLKLLLDHHINGVHLNIRPHTCHLCNKSFRKKFELSNHIKGHYNIRDKKCEVCGAAFYDHSSLSRHRRGHREKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00476178;
90% Identity: iTF_00550485;
80% Identity: -