Basic Information

Gene Symbol
Hivep2
Assembly
GCA_035045925.1
Location
JAWNOP010000052.1:11980588-11988575[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00029 0.022 15.2 0.2 1 23 418 440 418 440 0.98
2 8 0.0067 0.52 10.9 2.1 1 21 446 466 446 470 0.88
3 8 0.012 0.89 10.2 0.1 1 19 1061 1079 1061 1082 0.93
4 8 2.6e-06 0.0002 21.7 2.0 1 23 1773 1795 1773 1795 0.99
5 8 9.4e-06 0.00073 19.9 3.5 1 23 1801 1825 1801 1825 0.92
6 8 4.8e-05 0.0037 17.7 3.6 2 23 2283 2304 2283 2304 0.97
7 8 0.00074 0.057 13.9 1.2 1 23 2310 2334 2310 2334 0.91
8 8 0.0024 0.18 12.3 2.7 1 23 2355 2379 2355 2379 0.92

Sequence Information

Coding Sequence
ATGGAAAATGCAACAACCACAACGGCCAAGCATTACAAGACGACAGGAAAACAGTACAAGACCAATAAGGTGAACAACACGCGACgtgccacagcagcagcagcagcagcagcagcggcagcagcagcggcaacagtaacaacagtagcaacagcaaccagcAGCACGCCGGCAACCAAGAAGCAGACATATCGGGAAACTGCAACAACCACTCAGAGAACAGCTACTAGCAAGGCAAACAGAGCAGCTAGCACAGCCACAGCATCGACAGAGGCAACAGTAGCAACACcaccagcagtagcagcagcagcaacagttgccgatgttgccagcaacagcagcaacagcaagccCAGTACTAGCACACGCGATAAGCTGATCGATTTGCCTCTACCAGCTgccgacaacaacaaccacaataataataataataataataataaaaataataacaacaacaatcataataataataacaacaaaaacaacaacaaccacagtGATAATAGTATTAGTGAGaataattatgaatttaaGAGTTGTAGAGATAAAGCAAGTCTAAGTGATAGCAAAATGACGCTACAGCAGATGGCAGCCGTCAGCAGCAACAAGGAGCCAGTGGCTCCAAACAGCAGCAACTCCACCGTCACAGTCGCCGCCGCCGCGGTCGTTACCGCCACCCCCACCGACGAGGCCGCCTTCGGGGAGTGCTCGAACATTTCGCGGTATTTGCACAAGAAGTTCAAGCGCTTGGCCAGCACCACCGAGGTGGAGAACGCCAACGGCAATGGGAATCTGTCTGGGGATGCCGGCCGCACTACATCGCTGTCCTCAAATAGCTCACTttcgccgccaccgccgccgatGGTCGCCAATGGCCACCACCTGACCCAAccgccacagcagcagccgcagcagcaactgcaacaacatcCACAGCCACCGCCGCCGTCGACGCAGCAACATGACTTTAGTGCCAACTTTGTAAATAGCAATCATGTCAATGCCATCGGTCAGGAGGAGAGCCAGAAGGCAGTGCCCAGAACGCGAACGCCGctgagcagcagcaacagcaacacgaACAGCAACTATGCGGCAAATGCCACACTGTCGCCGGCAACATTCGCTCAGCACCAGCAGTTGACTCAGCCAACGGCAGGGGGCGGAGTGCcaggcggcggaggaggaggaggtggtggcggtggcggtggcgttGGAGTGACTACTCCCGCAGGTGAGAAGGCCGGACGGTATGTCTGTCCCTATTGCAATTTGATTTGTGCCAAGCCCTCGGTGCTGGAGAAGCACATCAGGGCACATACCAACGAGCGACCCTATCCCTGCGATCCCTGCGGCATCGCCTTCAAGACGAAGAGCAACCTGTACAAGCACTGCCGCTCCAGGTCGCACGCAGCCAGAGCCCGGGGCTTGGAGGTGCCACCAGATGCGGATGACGGTCTGTCCGACCAGGATGCGGAGCTGAGCAACAGTAGTTCGGAGTTGCCAAGTCGCGCTGGATCGCCATATGAGGAGCCCATGAGCTCGCCCACACCCTCGCCCTCCACCTTGTCGGCGGCGAAGAGTGCCTACATCCAGCAGCCGCCACTCCCCCAGCACATGCAACAACTGCCGCTGGGTTCGCCGGCGGCGGGGACTCTACCACCCGCCACGGCGGACAACCTGCACTCGGCCACTGCCCAGCACCGGTCGTCGGTTGACTACAAGCCATACAAGCCCAAGTTCCACAACGCCTCGCTTTACGCTCCTGGGAGTAGCAAggatcaacagcagcagcagcaactgcacttggtgcaacagcagcagcagcagcagctggtcCAGCAGAAGCTGTTGACGCAACTGCCGATGGTGCAGCAGCCATCGCTGACACATCCCACGCTCTCGCCCAGCACCCAGATGAAGATGAAGAATCACATCACATCGCACcagctgcagttgcagctgcagcagcagttgcacgCCCAGCAATCGCTCCTGGTCGGCCTGCCGCCGGTGCCCCCGGCTGGGGTATACTACCTGGGCCAGCCTCCCTATTACAATCAGGATCCTACCGCGGCTGCGATCCACCAGCAGCTGGTCCtccagcaactgcaactgcagcagcacaTCCACCTggcccagcaacagcagcaacaacagcaacagcagcagcaacactcTCCGTTGGTTAAGGCACCGCCGCCAACACCCCAGCCACCCAGTGTTCCCCCGCAACAGCTGGTGCGAGGCAACAGTCAGGTTTCGAATGTAaccccagccccagccacTCCCTCGCCCGCCACAAATCTGAGCAGTTTCGCCAGCTCCAGCGGCGGCATGCAAGTgAATGTGGCTAAAGTTCAGGAGCACATATCGAAGCTGATTTCGCACAACGAGGCCATTGTGGAGAACAAAGACATACTGCTGCAGAAAAAGTATCCCAAGCAGCTGAGCCGATCCCGAAGCTTCAACAACGCCAACGCCACTAGTGCGTCGCAACACGCCGCCAACTCGACGACCCAGCAAGCGAGCAGCAATCACATTGGTGCACAGATGCCGGAGCGGGAAGCCAAAGTTAACTTGGCCCAGGCCATTGtccagaaacagcaacagcagcagcagcagcagcagcaacaacagcagcagcagcaactgcagcaacaacaacagcagcagcagcaactgcagcaacagGAAGAGCatctgcagcagcaacggcagtATCAGATATACTTGCAACATaaggagcaacaacaacagcagctggAGCCCCCGAATGGATTGGCGAAGAGGAACAACTACAAGCCAGCCCCGTCGATAACCACGCCAGTGAAGCAGCAGCCGCACCTGCCACCGCCTCCCTCGCCACTGCCCATGCAGACAATGCAGTACCGTCAGGATCCGGCCACCCCGGTGGCCAAGATGGACCAACAGGCGGTGGGAGTGCATGTGATGCCTTTGAACTTGTCGGCGAAACCGAAGCCCGCCGTAGTTAGTCTGCCCGTCAGCTCCATAGCCACCAGTTCCGTGGCATCCACCCCCACGACCTCCACAGCTCCGACGGCCAGCGGCTCCAAAACTGCCCCGCCCACTGCCCAGCCAAACAACTCCATCATCAAAAATCTGCTCTTGAACGCCCGGGGATTGGCCGTGCCCATCGGAGAGGGCGACGACGCTGTCTACTCGTGTCCCATTTGTGCCAATGAGTTCCGCAGCGCGGACGAGCTGAAGCAGCATAACAGCACCTATTGCCAGGATGCGAGCTCCAGCGCCCCGATGAGTCCGGCCTCGTCGCCCTTCCGCTCCAACTCGATCTCGCTCAGCCTGCCGGAGCTGAAGAACCACATCGCCAACTCAAAGAATCCTCTGTCGCTGGCCAAGCTGGCCTGGTGTCAGCTGAAGACCAAGCGGAGCTGCCTGGTCCTCAATCGCCTGAATGCGGCTCAAACCCACGCGAGGACCTCTACGGTGACGGCTCCCACAGCCACTCCTCCGGCAACTGCCCCTACCACTGGTGCGGGCCCAGCTCCAGCTCTTCCCAGTGCTCCAGTTAGTCAACCAATAGTAGCTCCCACAGCCATTGAAGCTCTGCGCTTTGTGGACGCACCACTGCCATCGCCAGGACCTCTTCTGGGAAAAACGCCACTGGTGGACTATGCCCAGCAGAATACACCCCGCAAGGCCCAAGACTCCGTTGTGATTACGAAAATGCACGAGGACCGGCAGTTCCCTGTGGATCTCGACGCCCAGCCGGCCAAGCGGGTGAAGACTAGCGATGTCGCCATAGTTCCCTCCCAGACTCAGCCGCAGGTCTTCACATTTCCGTTCAGCAGCGTCTCGGAATCGCAGTCCAGCAAGGAAGAGCGCTTGCGGAGATTAACGTCCTCCGGAGGCACTATGATTCCCATCTCGGAGTGCCCTGAGCTGGAGAAGAGTCCCAGGGTGATACGCACTTCGCTGTTGTCGGGCGGAAGCTTCCTGGAAGTCGGAAGTACTTCCAAGGTCAACGAGCCGGGATCGGGCAAGGACCGGAAGCTACTGCCGCTGCCCGGTGGACTCTCCACGGGCGCCCAGCACTTTCAGTTCCCGCCCATCAACTCGATTACTGGCTTCAATCCGCTGACACTGCCCCAGATGGGCGGCGGGGACAAGACTACCCCCAGCACACCGATTCCCTACGTGCCGGGCATCCCAGGACCTGGCAGTCTGACGCCTCAGATGCCCCTGCTTCCACCGCCGCCGCAACAGTTGCAGCTGCCGGTGGCCACGGGTCGCGGCCGCAGTCCCAACCGGAAGCAGCCCAGTCCGCTTCTGATGGCCGGCGCAGCTGCTGGCGAGCTGAAGGCGTTGTCTCCCTTCGGCGGAGTCCAGAATCTCCCCAGCGAGTTCAGCCGACTGCCGCCAACGCCCGCCCAGCGTCAGGCCCTCCAGTGGAACAGCAAGGAGCCCGGCAAGAAGGCTCCGTTCAACTTCCTGCGAATGGCCGACAACGTTAAGATCTCTGAGCCGGAGGTGCGTCACTTCAACCTGGACAGCGTGATTGCGggcaagcagcagcaggagtcGCCTCTAACGCCGCTCCACGTGGACACGCCGAACGGAGTGGCCACCGAGGAAGCGAGTGCCCCCTCTACGTCCAGTTCCTCCGCCAAATCCAAGTTCCTGCGACCCACCAGCCTGCCCCTGAAGCCGGGTACGTTTACCCCGAAACGCCATCACGGAATCACTCCCACGGCCAACACACTGCCACTCATTTCTCCGGAGACGCCGAGGCCGTCGAAGTCGTGCGTGCAGCTGTATCTGAACGGGCATGCCTACACCTACCTGGGCCTGAAGTGCAGCACCAAGATGTTCTACTGCACGGTGAACTGCCCGCAGCCCTCGTACGTGGCCGGCATGCACAAGCTGTCGATGTACAGCGTGTGGCAGGTGTGCGAGGAGAACCAGCCGCATCCTCTGGGCTTCAAGCTGAAGCAGGTCATGGGCCTCTACGACTCCCGCCAGAGGATGTTGGGCAACGTGAGCACTACTGCGATGGCTGGAACCGGGAAACTGAGCTACGGCCTGGTCTCGTCCCAGCAGATCGTGTGCTCTCCCTCGCCCAACGCCAGTGGTAGTGCCTTCTACCAGGCCCAACAGAAGTCCGCTCCCGCCGTCCAGGTGGGCGCTCTCAGCGAGGCGAATGTGGCGGCCAAGGCGGCCAACGATGAGGCGCAGGCCAAGAAGCTAGAGACCAGCCCGTCCGGACAACCGCTGGTGGGCGGATACGAGTCGCACGAGGACTACACCTACATCCGGGGCCGAGGAAGAGGCAGGTATGTCTGCTCCGAGTGCGGCATTCGCTGCAAAAAGCCTTCCATGTTGAAGAAACACATTCGTACTCATACGGATGTGAGGCCTTTCACATGCAGCAACTGCAATTTCAGCTTCAAGACCAAGGGCAACCTGACCAAGCACATGCAGTCCAAGACGCACTTCAAGAAGTGCATGGAACTGGGCATCAACCCAGGACCCATGCCCGCCGATGGCGAATTTTTGGACGTGGACATGGACTTTGATCAGCAGTCGTCCACTTCGGCGGGAGGACGCACATCCTCCATGGCCGGGGAGTCCGATTCCGATGACTTTACCGACAACGAATCGGAAAGCAGTGACACGGATGAGTCGAAATCGCGCCTGAAGGAGCACGAGGCAGCCAGATGCCTGTTGTCGCTGTCCATGACGCCGCCCATTCCTCAGAGTGTTTCTCCTTATCCCCAGCTGCAGGGGGATACACCTGTTCCGGCCGCCAGCCCGGCCAACAGTATTGGATCCTCGGGATCGCAGCCAAAGCGATTGGTTTGCTCCTTCACCTCGCCGAAGCCTCCGTTCGACTATCAGAAGCAGGAACAGTATTACTCCAATCCGGAGGAGTCCAAGCCAAAGCGAAGCGTGGCCAGCGAGGAGAGCGCTCCGATGGATCTCACCAAGCCGCGTAGCTCCGCGTCGGCCGTCTCGCCtttgccgctgctgccgccagTCCAGGACCTCCCCAAGTCGCAGGCCCAGCAGATGCGCGAAGTGATCTTCGGCAGCTCTGGCAACGAGAGCGGCTTCATGAAGACCCTGATTTCGGTGTCGGACAAGGTGCGCATCTCCGCCGAAATGGAGGAGCAGGCCAAGCTGGGGGCCGAGGGCGAGGACGTGCTGCTGCAAACGTACATCAAGGAGCAGGCGCTCCACCACGCCAAGATGAAGCAGAGCCAGTTCAGCCGCAGCTACCTGATCAACACGCTGTTCTCCACTGCGGCGCCGGTGATGAGCAACAGTGCCAACCTGCTGACCACCACCAGCAGGCCAGTCATGAGCATTAACGAGGTGCCCAGCATCGAAGTGCACGAGGTGAAGACACCGGACGAGGTGCCAACTGTGGCTCCTGTAATtccggctccagctccagtaTCGGCTCCAGCTCCCTCGGCTGTCACACCCGTTGCCAACGTTGCTCCGGAGGAGAGCGAGGAGAGCGACCACAAGAAGTCCAAGGTGGAGCGACACAATGCCAATCTGCCGGCTGCAGTGCAACAACCGGATGTCAATGACTTCAGCGGAGTGCTGAGCGGCCCATCCTTGGCCCCAACAGCACCGCCAGCATCTGTGGCCGCGTCCACTCCCGCACCTGTGGTCACGTCCACCACAGCCACCACGCCCAGCGTCTCATCCCAGCCCACGCAACGCACTGTGATTGTGGGCGAAGATGGCTTCAAGAACTCCACGCCCAGCAGCAAGAGCAGCGATCTCCAGCCGGGTCCCTATGCCCGGGGAATGCCACCTGCTCCTCCGCCGATCGCCGCCGATGCCCGACCCACCTGCACCATCTGCTCGAAGACGTTCCAGCGGCAGCATCAGCTCACCCTCCACATGAACATCCATTACATGGAGCGGAAGTTCAAGTGCGAGCCCTGCAGCATCTCCTTCCGCACCCAGGGCCATCTGCAGAAGCACGAGCGATCCGAGGCGCACAAGAACAAGGTGATGATGACGTCGACGTTCGGAGTGCCCACCACTTCCAATCCCCGTCCCTTCGAGTGCACCGACTGCAAGATCGCCTTCCGCATCCACGGACATTTGGCCAAGCATCTGCGCTCCAAGACCCATGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCGTTTGGAACGTACGCCGAAATCGAACGGGCCGGCATCAGTCTCACGGAGATCGACACCAGTGACTGCGAGAATTCATTGATTTCCCTAAAGCTACTGGCCCAGAAGCTGCTGGAGAAGGATCCCAACAAGCTGAGCGGCTACACGACGCCCTCGGGAATGATGCAGCTGGCCCAGGACGCCACTGGCCCCACCTCGCAGGACAGTGCCTCCGAGGATGGGTTCAGTGCCGCCATAGCCTCGGCCATTGCATCGCTGGACAACGACAGTGCTGGGAACACACCGAAGCGTGCCAGTTCTATGTCCGAGGACGAGACAGTGACCAATGGCCTGAACCATAATCTGAAGCGACGTCTGCCGGGAAGCTTCAGCAGTACCGGCGAGGAGAGCGACAATCCGGCGGAGGGTAGTGGCGAGAAGCGAGCACGATCCGGACAAGAGATGCCCGTTCCGGTGCCCGTGGCTGTTCCGGTGGCCGCCTCGGCGGCAGCCAGCAACTGA
Protein Sequence
MENATTTTAKHYKTTGKQYKTNKVNNTRRATAAAAAAAAAAAAATVTTVATATSSTPATKKQTYRETATTTQRTATSKANRAASTATASTEATVATPPAVAAAATVADVASNSSNSKPSTSTRDKLIDLPLPAADNNNHNNNNNNNNKNNNNNNHNNNNNKNNNNHSDNSISENNYEFKSCRDKASLSDSKMTLQQMAAVSSNKEPVAPNSSNSTVTVAAAAVVTATPTDEAAFGECSNISRYLHKKFKRLASTTEVENANGNGNLSGDAGRTTSLSSNSSLSPPPPPMVANGHHLTQPPQQQPQQQLQQHPQPPPPSTQQHDFSANFVNSNHVNAIGQEESQKAVPRTRTPLSSSNSNTNSNYAANATLSPATFAQHQQLTQPTAGGGVPGGGGGGGGGGGGGVGVTTPAGEKAGRYVCPYCNLICAKPSVLEKHIRAHTNERPYPCDPCGIAFKTKSNLYKHCRSRSHAARARGLEVPPDADDGLSDQDAELSNSSSELPSRAGSPYEEPMSSPTPSPSTLSAAKSAYIQQPPLPQHMQQLPLGSPAAGTLPPATADNLHSATAQHRSSVDYKPYKPKFHNASLYAPGSSKDQQQQQQLHLVQQQQQQQLVQQKLLTQLPMVQQPSLTHPTLSPSTQMKMKNHITSHQLQLQLQQQLHAQQSLLVGLPPVPPAGVYYLGQPPYYNQDPTAAAIHQQLVLQQLQLQQHIHLAQQQQQQQQQQQQHSPLVKAPPPTPQPPSVPPQQLVRGNSQVSNVTPAPATPSPATNLSSFASSSGGMQVNVAKVQEHISKLISHNEAIVENKDILLQKKYPKQLSRSRSFNNANATSASQHAANSTTQQASSNHIGAQMPEREAKVNLAQAIVQKQQQQQQQQQQQQQQQQLQQQQQQQQQLQQQEEHLQQQRQYQIYLQHKEQQQQQLEPPNGLAKRNNYKPAPSITTPVKQQPHLPPPPSPLPMQTMQYRQDPATPVAKMDQQAVGVHVMPLNLSAKPKPAVVSLPVSSIATSSVASTPTTSTAPTASGSKTAPPTAQPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKQHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKNHIANSKNPLSLAKLAWCQLKTKRSCLVLNRLNAAQTHARTSTVTAPTATPPATAPTTGAGPAPALPSAPVSQPIVAPTAIEALRFVDAPLPSPGPLLGKTPLVDYAQQNTPRKAQDSVVITKMHEDRQFPVDLDAQPAKRVKTSDVAIVPSQTQPQVFTFPFSSVSESQSSKEERLRRLTSSGGTMIPISECPELEKSPRVIRTSLLSGGSFLEVGSTSKVNEPGSGKDRKLLPLPGGLSTGAQHFQFPPINSITGFNPLTLPQMGGGDKTTPSTPIPYVPGIPGPGSLTPQMPLLPPPPQQLQLPVATGRGRSPNRKQPSPLLMAGAAAGELKALSPFGGVQNLPSEFSRLPPTPAQRQALQWNSKEPGKKAPFNFLRMADNVKISEPEVRHFNLDSVIAGKQQQESPLTPLHVDTPNGVATEEASAPSTSSSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMGLYDSRQRMLGNVSTTAMAGTGKLSYGLVSSQQIVCSPSPNASGSAFYQAQQKSAPAVQVGALSEANVAAKAANDEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSNCNFSFKTKGNLTKHMQSKTHFKKCMELGINPGPMPADGEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDFTDNESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYPQLQGDTPVPAASPANSIGSSGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVASEESAPMDLTKPRSSASAVSPLPLLPPVQDLPKSQAQQMREVIFGSSGNESGFMKTLISVSDKVRISAEMEEQAKLGAEGEDVLLQTYIKEQALHHAKMKQSQFSRSYLINTLFSTAAPVMSNSANLLTTTSRPVMSINEVPSIEVHEVKTPDEVPTVAPVIPAPAPVSAPAPSAVTPVANVAPEESEESDHKKSKVERHNANLPAAVQQPDVNDFSGVLSGPSLAPTAPPASVAASTPAPVVTSTTATTPSVSSQPTQRTVIVGEDGFKNSTPSSKSSDLQPGPYARGMPPAPPPIAADARPTCTICSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMMQLAQDATGPTSQDSASEDGFSAAIASAIASLDNDSAGNTPKRASSMSEDETVTNGLNHNLKRRLPGSFSSTGEESDNPAEGSGEKRARSGQEMPVPVPVAVPVAASAAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00550443;
90% Identity
iTF_00550443;
80% Identity
-