Basic Information

Insect: Drosophila athabasca
Gene Symbol: -
Assembly: GCA_008121215.1
Location: CM017796.1:9625586-9631913[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.06 4.1 7.8 0.3 1 23 605 627 605 627 0.96

2 7 0.29 20 5.7 0.6 2 19 632 649 631 650 0.97

3 7 5.5e-06 0.00038 20.5 0.3 1 23 656 678 656 678 0.99

4 7 0.0028 0.19 12.0 4.2 1 23 688 710 688 710 0.98

5 7 0.00065 0.045 14.0 0.1 2 23 717 738 716 738 0.95

6 7 1e-06 6.9e-05 22.8 1.3 1 23 744 766 744 766 0.98

7 7 7.6e-05 0.0052 16.9 3.5 1 23 772 794 772 794 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.06	4.1	7.8	0.3	1	23	605	627	605	627	0.96
2	7	0.29	20	5.7	0.6	2	19	632	649	631	650	0.97
3	7	5.5e-06	0.00038	20.5	0.3	1	23	656	678	656	678	0.99
4	7	0.0028	0.19	12.0	4.2	1	23	688	710	688	710	0.98
5	7	0.00065	0.045	14.0	0.1	2	23	717	738	716	738	0.95
6	7	1e-06	6.9e-05	22.8	1.3	1	23	744	766	744	766	0.98
7	7	7.6e-05	0.0052	16.9	3.5	1	23	772	794	772	794	0.98

Sequence Information

Coding Sequence: ATGAATAGGAATATAAGAAAAGGTGCAGGAAGAGGTGCAGTGCGAAAAGCAGTGGAGGTAGAGAGAAGAAGCAGGAGAACCGGCAGGTTGCGCCCCCGCCCTCCCTCACCCTCGTCCACATTTacactctctcacacacacactcttatcagccagcaaacagcagctccatctccacccACTCTCATAGCAGGAGGACTGGGGGATAATACCATGGCCAGCAGTGCAACAAATGCAGCAAGCATCCGAAGCACaagcaccaacaacagcagcagtagcactGCTCTGCCATCACTATTCTCCTCTGCGTCCgccgccgctgcagcagccacCTCAAAGGACATGGACGGACTGATTGCCATCAATGATAGCGCATTATCGCAACAAATCGAATTTATACTACAAGATGCTCCTATGGAGCAGGATGATGACCATCAAcagcaccatcaccaccaccggcaccaccaccataaccaccaccatcagcagcagcatcaacaccaccagccgcagccacagtcgcagcagcaccaccaccaccagtcgcagcagcagcaacagcagcatctgcAACCACATCATCAGCTGGTAGTAGGAGCTGGATCTGGAGGTGGAACAGCTGCGAAGCTCGAGAATAACCACCcaccgacaacaacaaccgctGCAGCAACCGCAACGGCAACCAACAGTGCTTCCGTTTCCACctacaccaccaccagcagcaatagcaacaacaatcacCTGGAGGAGCATCATCACCTGATgatccaacagcagcaacagcatctgCTAAATGGCCGGCGTGTTATCATCCAGTCAACCGGTAACAGCAGCACGGCAACAGTATTGGCGGCCAGCGACataaaggaggaggagctggacgaggaggaagaggatCCTGAGCTGAACGATGAGAATCTTCAGGATATCGAGGAGGAGGCCCAGGCGGCCGAAGCCGACGAGGAGCCAGAGACGACCGCACAGCAGCATCCGCACCTTCAGACTCGCGTCAAGATCGAGGTGGAGGACGACGATATGCCCGAagatgatgacgatgaggaggaggacgaggatgaAAACATGTCGGTGGCCCATCtccagcggcagcaacaggcCCAGGctcaagcccaagcccaagcccaggcccaATTGGAATATCAACTGCAATCGACGCAAGGGGGCGGGTCAGGCGCCCAGCAGTTGGTGCAGCTTCCCGCCGGTAGTCTAATGAGCACCTCGAATAACCGTACTATGACTGTGCCCGTCACCGAGGCGGCACTCGTTCAGCTGCAGCGCCGTCCCGTGTATATCAGCAATGCTGTGGGCAGCCTGTCCGCCGGCACCACCTATGTACGAATGCCCGGAGCGGCCGTGATCAGTCGGAGTCCGATGACGGTGCTAAATGTGGTGCAACAGACAGCGGCCCTACCCGCGACCCAATTGATCCTGCAGGCCCAGAGCCCAACGCctcaacaacagcagcagcagtcccaacccgagcagcagcagcagcagatggccataaaccaacagcagcagcagcagcagcagacacaatTGCAATcacagcagccgcaacagcagccgcaacagcagccgcaacagcagccgcaacagcagccgcaacagcagccccaacagcagccgcaacagcagccgcaacagcagccgcagcagcagcaacagctacagctatCATCCCATCCCGTGAAGCACCATCAAGCATCGCCAGCATCCAGCTCTTCCCCATGCAGCAGTAGCGGTAGCAGTGGGGCCAGCAGCACGGGGGCCACCGCCAGCTCGACGAGCAGCTACCAGTGCATGGAGTGTGTGGAGAAGTTCGAATCGAAGGAGCTGTTCGACATCCATCGCAGCGGACATGCCAACAACATGAAGTGCGCCATCTGCAACATGGTGCTCAAGTCCCTCAAAAACTACGAGAAGCATTGCCTGCGTTGCAAGCCGTACGAGTGCCAGATCTGCGGCCGGGTGGTACGCTTCCGGCCCAACTTCATCAAGCACATGCGGGTGCACACGGGCCAGCAGTCGGAGCGGCACAAGTACAAGTGCGAGGTTTGCCACAAGGAATTCATGAGCTTCGAGTACTTCAAGGTGCACAAGAAGATCCACAACGAGAATGTGAATCTCACCTGCGAGATCTGTGGCAAGGTGTTCAGTGCCCTGGCCTCGCTGCGCGGCCACTCGAAACTCCATTCGGGGGTCAAGCTGCACAAGTGCGATGTCTGCGGCAAGGGTTTTGGCCAGCGCTACAACCTGAAGATCCATGCCCGCACCCATACGGGCGACTTTCCCTTTGAGTGCAAAGTATGCAAGAAGAAGCTCCACACACAATCCTCGCTGCAGACGCACATGCAGGTCCATCTCAGGGACCAGCCGGCGGCAGCAGCCACGCAGCAGGCAAAGCAGGCCAGcaatgccagtgccagcaGCCAGAACGGGGGGAGCACAACCAATAATACAAATACCAgcaccacccacacccacaccagcagctgcagcaactcgagcaacagcaacagcaatagtGCGACAACCGCTACGGCAACAACGATTGTCAAACTGGAGCCGCCAAGCGATCTGGATATGCCTAGCACTAGCACAAGCAACAGCAatcagctgcaacagcagcaccactcacaccaccagcaacagcagcaacaacaacagcagcaactgcaacagcagcagcaaatggaATTGGACGACCATTCTGGCCTCAGTGGGGACGAGGATGTGAACTCTTCCTCGCATATTGTCAACTCAACCACCAATCGCTTGACCACCGGTGAGGATTCATCCAATGAGTCCTCGAATGCCTCGCTACACAATCAGCCGCACTCCTCCTCATCCGCAGCCAGCATCAGCTCCTCGCATTCACCATCTatgctgcagcaacagcagcaacaggtgCCCACAGCATCGACACAGTTTCTCATGTCCACGCCCTCACGGACGATTGTTATCAAGAACTAcatgcagcaacagcagcagcagcagcaacaacatacAGGAGCGGGGCAGGGACAGGTACAGGGACAGCATCATCAACAGAACGGACCCGATCAGAGTGCAGTACTCCATACGCAGGTTATCCAGAGCGGTGcaggcaccagcagcagcggcgccagcagcagcagcaatggcagCGGGAACGCCATCGTTAGCAATGGTACACAGCAATTGATACGCAAGACGCCCATCATTCATCACTCAAcgagcggcagtggcagtggcactctCAGCTCCGCTTTGGCCAGTGCggtgcagcaacagcacacaggagCTGGTTCGCCCGCTCAATCGCCACAGTCATCATCGTCAACGTCTTGCTCCTCCACCACTGTGCTGGTGTCCAAGGCCACGGGTGTACCCCTATCGATAGCCTCctcggcagcggcggcggctgcccTGTCCGGTTCTACCATCATACGGAGCACACGCAGTCATCATCATatacagcagcaacagcagcagcagcatagcaacagccagagtcagagtcaacagcagcagcgtggGTCAGGAGCTGGGACGCAGCAGCGCAATAACCACCGAAACCACCACCGACGTCGTCATCTTGCAGACATGGATGATgaggacgatgacgatgaggacgaagatgcagccacagcagccgctCAATTGCAGTTGCAGCGCCATGGCCAACAGTCGTCGTCCATGTCCGCCagcccccaccaccaccaccagcatcagcagcaccaTCATTCACATCATCAAcagaatcagcagcagcatcagcagcaacagcagcagctccatcatcaccatcatcatcatcacaaTCATCATTtcgatgatgacgatgacgatgagaAATCATCACCGTCCCTGGCCACAGCGGCCATCAAGGTGGAACCGAATCTCTACTCCTCCGGCTCCGGCGACAACTCCAACGATATGTTCATCAAAGAGGAGGTAATGTTCGAGGACTCGGCTGCCCCACATTCACCACAATCGCCGCCCAGCTCAAAGTTTCGCATATCGAACTTTGATAGCGATCTGGTCGATCACCATGTCGATTTGAACCACTCGCTACCGCCGTATGGGAACCTCTTTGAGCCGCATTCGATACCCGATAGCATACCCGTGCAACTCTATccggatgatgatgatgacttTCGGCTGGACCATAGCTCGTTGGGTGGACTGCATAATACATCGTCATCGACAACAGATGGGGACTTTATCAAAAAGGAATGGGTCTATGGCACCGGCACCAGTTCCTATGCCATGAATGGTAAATTCGATGATGACAGCGATGCCCTATGCGATGCTGCAAATTTTATATACAATTGA
Protein Sequence: MNRNIRKGAGRGAVRKAVEVERRSRRTGRLRPRPPSPSSTFTLSHTHTLISQQTAAPSPPTLIAGGLGDNTMASSATNAASIRSTSTNNSSSSTALPSLFSSASAAAAAATSKDMDGLIAINDSALSQQIEFILQDAPMEQDDDHQQHHHHHRHHHHNHHHQQQHQHHQPQPQSQQHHHHQSQQQQQQHLQPHHQLVVGAGSGGGTAAKLENNHPPTTTTAAATATATNSASVSTYTTTSSNSNNNHLEEHHHLMIQQQQQHLLNGRRVIIQSTGNSSTATVLAASDIKEEELDEEEEDPELNDENLQDIEEEAQAAEADEEPETTAQQHPHLQTRVKIEVEDDDMPEDDDDEEEDEDENMSVAHLQRQQQAQAQAQAQAQAQLEYQLQSTQGGGSGAQQLVQLPAGSLMSTSNNRTMTVPVTEAALVQLQRRPVYISNAVGSLSAGTTYVRMPGAAVISRSPMTVLNVVQQTAALPATQLILQAQSPTPQQQQQQSQPEQQQQQMAINQQQQQQQQTQLQSQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQQQLQLSSHPVKHHQASPASSSSPCSSSGSSGASSTGATASSTSSYQCMECVEKFESKELFDIHRSGHANNMKCAICNMVLKSLKNYEKHCLRCKPYECQICGRVVRFRPNFIKHMRVHTGQQSERHKYKCEVCHKEFMSFEYFKVHKKIHNENVNLTCEICGKVFSALASLRGHSKLHSGVKLHKCDVCGKGFGQRYNLKIHARTHTGDFPFECKVCKKKLHTQSSLQTHMQVHLRDQPAAAATQQAKQASNASASSQNGGSTTNNTNTSTTHTHTSSCSNSSNSNSNSATTATATTIVKLEPPSDLDMPSTSTSNSNQLQQQHHSHHQQQQQQQQQQLQQQQQMELDDHSGLSGDEDVNSSSHIVNSTTNRLTTGEDSSNESSNASLHNQPHSSSSAASISSSHSPSMLQQQQQQVPTASTQFLMSTPSRTIVIKNYMQQQQQQQQQHTGAGQGQVQGQHHQQNGPDQSAVLHTQVIQSGAGTSSSGASSSSNGSGNAIVSNGTQQLIRKTPIIHHSTSGSGSGTLSSALASAVQQQHTGAGSPAQSPQSSSSTSCSSTTVLVSKATGVPLSIASSAAAAAALSGSTIIRSTRSHHHIQQQQQQQHSNSQSQSQQQQRGSGAGTQQRNNHRNHHRRRHLADMDDEDDDDEDEDAATAAAQLQLQRHGQQSSSMSASPHHHHQHQQHHHSHHQQNQQQHQQQQQQLHHHHHHHHNHHFDDDDDDEKSSPSLATAAIKVEPNLYSSGSGDNSNDMFIKEEVMFEDSAAPHSPQSPPSSKFRISNFDSDLVDHHVDLNHSLPPYGNLFEPHSIPDSIPVQLYPDDDDDFRLDHSSLGGLHNTSSSTTDGDFIKKEWVYGTGTSSYAMNGKFDDDSDALCDAANFIYN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603687;
90% Identity: iTF_00474128;
80% Identity: -