Basic Information

Insect: Drosophila athabasca
Gene Symbol: zfh1
Assembly: GCA_008121215.1
Location: CM017793.1:10520691-10558727[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0028 0.19 12.0 1.9 2 23 80 102 79 102 0.95

2 9 0.00088 0.06 13.6 0.2 1 23 314 336 314 336 0.96

3 9 0.00011 0.0076 16.4 1.7 2 23 351 372 350 372 0.97

4 9 5.5e-06 0.00037 20.5 6.3 1 23 381 403 381 403 0.99

5 9 0.00033 0.022 14.9 1.2 3 21 411 429 409 430 0.94

6 9 0.0092 0.62 10.4 1.8 2 21 675 694 674 695 0.92

7 9 1.5e-05 0.00099 19.2 0.5 1 23 1056 1078 1056 1078 0.94

8 9 5.4e-05 0.0037 17.4 7.4 1 23 1084 1106 1084 1106 0.98

9 9 0.0027 0.18 12.0 4.3 1 21 1112 1132 1112 1133 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0028	0.19	12.0	1.9	2	23	80	102	79	102	0.95
2	9	0.00088	0.06	13.6	0.2	1	23	314	336	314	336	0.96
3	9	0.00011	0.0076	16.4	1.7	2	23	351	372	350	372	0.97
4	9	5.5e-06	0.00037	20.5	6.3	1	23	381	403	381	403	0.99
5	9	0.00033	0.022	14.9	1.2	3	21	411	429	409	430	0.94
6	9	0.0092	0.62	10.4	1.8	2	21	675	694	674	695	0.92
7	9	1.5e-05	0.00099	19.2	0.5	1	23	1056	1078	1056	1078	0.94
8	9	5.4e-05	0.0037	17.4	7.4	1	23	1084	1106	1084	1106	0.98
9	9	0.0027	0.18	12.0	4.3	1	21	1112	1132	1112	1133	0.96

Sequence Information

Coding Sequence: ATGCTGACATACGGGCGAAAGGAACAGGACAGGAACAtgagtagcagcagcatcgggaacagcaggagcagcaggaacaggagcagcaggactCGACTCAGAGGTAAATGCCGAGTTCCCTCTTTGGCTTCCAGTCTGCACCACCACCAGGCACCGCACAGCAAGCCGATCAATGGCTCCGGTGGCAGCCAGGAGCAGCACGCACAGCCAGGTGTATCCGTCGATGATTTCCTGGTCAAGTGCACGCAGTGCCACAAACGCTTTACAGAGTTTCAGTCCCTCAGCGAACACATTGCCAGCGAGCATCCGCACGACAAGCTGAACTTTGAGGCAAGTCGTGGCTCCAGCGGTGCCGTGCAGCCGGAGAGCGATGCCGAGGACGAGCAGAGCAATCTGAGTGGCAGCCGATATGCCAAGTCCcctgccaccaccacccatgccacgcccagcaacaacaacaacaacagcgatctGGCCAagaaccacaacaacaacaacaacagcaacagcagcagcagtaagcTCTCTCCGATGTGCTCTCCCGGTTCGGCGGGtcccaccaccgccgccgcagaTCTCTTCGCCCACCTCTCACACGGAGCCCCGCCCCAGCTGCCCCCCCACCTGCACGCCCAGTTcatggccgccgccgccctgGCCATGCAATCGGCCCGCTCCGTCAGCTCCTCCGCCAGTTCGCCCAACagccaccatcaccaccagcagcaccagcagcaacagcagcagcagcagtcgcaccttcatcatcaccagcagcagcagcagctccaccagcagcagtcgcagcagcagctgctgccgcccCAGCTACCGggtagcaacagcagcgtggGCAGCAATTCCGCCTACGATCTGGACCTGAGTGCCCCACGCTCCACCTCCAGTCCGGGCTCTACCACCGGCGACCTGAGCGGCGCCTATCCCTGCATGCAATGCACCGCCTCCTTCAGCAGCCGTGAACAGCTGGAGCAGCACGAGCTCCTACACTCGCCCACCGGGGGCCAGCCCACGGCACAGAATGTCtctcagACCTGCCGAATCTGCCACAAAGCCTTCGCGAATGTCTACCGCCTGCAACGGCACATGATCAGCCACGACGAGTCGGCGCTACTGCGCAAATTCAAGTGCAAGGAGTGCGACAAGGCCTTCAAATTCAAGCATCACCTGAAGGAGCATGTGCGCATCCATTCCGGCGAGAAGCCCTTCGGCTGCGACAACTGCGGCAAGCGATTCTCGCACTCCGGCAGCTTCTCCTCCCACATGACCTCCAAGAAGTGCATCAGCATGGGCCTCAAGCTGAACAACAATCGGGCGCTTCTCAAGCGCCTGGAGAAGAGTCCTGGCGCCGCCGGTCCCCGACGCTCGCCCACGGACCTACAGGGCCCCAAAAACGGTGCCGCAAAGATGACCGATCAGCAGTCCCTGCCACCGCTGCCCAATCCCATGATCTATTTTGCCGGCGAGGCACAGGCGCAAGCTGCTGCCGCGAATGGAGCTCCTCCACCGTTCTATCCCAACTACATGAATGCGGCTCTGTTAGCCTTTCCCAATCCCTTCATGGCAGCGGCTCTGGATCCGCGCGTCCATCCCTACAGCATACAGCGACTTCTGGAGCTGACGGCCGCcggacagcagcaacaacatcagcagcagcaacgcgaGGAACGcgaagagcaggagcaggatcaGCACGAAGAGCCTGAGACGCCGGAGGAGCCGAAACTGGTCATGGACATCGATGAGTCTGAGCGTATGGTGCCACAGGCAAGCCCTCAGATTATGCCAGAGGAGATCGAACCCGTTGTCGACATGGCCGTTGCTCCCATAAAGCAAGAGCCCAGCCGCGAGCCCACCCCACTCCCGGAGAGTGCACCGCCCTCGCCCAAGTCCTtcaagcaggagcaggaggagcccCGTTCCGTAGAGGAGGATCAGCCCATGGAATCGGCTCAGCCCGAAGTCTCTGTCTCCTCCCCCAGGGTGGACACACCGGCCGAGCTGCGGTGCAGCCGCTGTGACAAGCAGTTCAACCACCACACGGAGCTGGTGCAGCACGAGAAGGTCCTCTGCGGCTTGATCAAGGAGGAGCTCGAGCAGCActaccaccagcagcagcagcaacaacagcaccaccaacatctccagcaacagcagcatcagcagcaggctgCCTTTGCCTTGCCCTCTGCCAGCGAGgatgacgacgaggaggagcgcGAGAATGACAACGACACGGAGCCACGTCAAGACAGCAACGAGCGCAAGGTGCGCGTGCGCACAGCCATCAACGaggagcaacaacagcagctgaAGCAGCACTACGCCCTCAATGCGCGGCCGAGTCGCGACGAGTTCCGGATGATTGCGGCCCGCCTCCAGCTGGATCCGCGCGTGGTCCAGGTCTGGTTCCAGAACAATCGGTCACGCGAGCGCAAGATGCAGAGCTATGCGAGTGTCCACACGGCAGCTCCAGCCGCCAATGAAGTGCCCACCACTCCAGTGGCCAGCCGTCCCACGACCGAGGATCAGCCCCTAGATCTGTCGGTGAAGCGCGACTCCTTGACGCCCAAGAGCGACCACTCCGCCGTGTACGGATTGCCCCAGCAGCAGGCTGCCGGACAGCCAGCCCCCGCCGACTTCCAGGAGGCCATCAACCTGAGCCGCAAGTTCTCCAGCTCGGCCTCCATGTCACCAGCCTCGCTGTCGCCCTCGTCGGGCGCCTCTCTGCAGCAATCCTCGGCAGCTgcggccgccgctgctgcagcccTCTGGCCCTTTGGCGGCCCGCCTCCATCGCCCCCCAGCCAGCACGAGGCCACGCCCGCCCAACACTGCTCGACGCCGCGTGGCGGCCAGGCCTTCCCTGGACTACCGTACATGCTGCCCATGCAGCGGCTTCCCATGGAGGCCCTCTTCCAGATGCGCCCTGGAGGCGAGTACGCCCCCAATCCCCTGATGAACAGTATTAAGATGCCCGACTTTCGCGGCACCAGTCTCAGTCCGGGCGGCTCCGAGAAGCGCTCCTGGCGGGACGACGACTCGCGCATCTCCCACGAGGACGACTTCGGCAACGGCCTGATGCCGCCCAAGGGCCGTCGTGGCAAGGCCGAGACCCACGGGCATGCCGGCGATCCAGATCTGCCCTTTGTCTGCGACCAGTGCGACAAGGCATTCGCCAAGCAGAGCTCCCTGGCGAGGCACAAGTACGAGCATTCCGGTCAAAGACCCTACCAGTGCATGGACTGCCCGAAGGCTTTCAAGCACAAGCATCACCTGACGGAGCACAAGCGTCTGCATAGCGGAGAGAAGCCCTTCCAGTGCTCCAAGTGCCTGAAACGTTTCTCGCATTCGGGAAGCTACAGCCAGCACATGAACCACCCAGCCGCCTCGGGAACGGGGCCACCGGCTCCTAGTGGACGCCGTGGTCGCGGCCAGTCGGCCTCCGCCCGATCccaggccagcagcagcacttacccgccgcatccacatccgcaccagcatcagcaccagcacccTCATCCCCACCAGCATCCGCTGGCGGCCATGGCCGCcttccagcagcaacagcagaggatgcaccaacaacaacagcaacagcagcgtctCTCCTGGCCACCGTCCGTGCCTGGGGCTGGAGTCATGCTGCCACCACCATccaatcaacaacaacagcgtCCCACGGCACCGCCACCACCTCTGCTTTCGGGCGCAGGATTTGGACAGCCGCCACCGCAGTTCTTTCACCATGCCGGCCTGCTGCCGCCACCAGCCCCACCATCGGGGGCGGGAAATGTGCGATTTGCCGCACCAGCAACGCCGCCCTCGGTCGCTCCGTCCCACGGCGGGGGTCCCGCCTTTGATTTCTTCAATGCCAAAATGTTGCTCCACTAG
Protein Sequence: MLTYGRKEQDRNMSSSSIGNSRSSRNRSSRTRLRGKCRVPSLASSLHHHQAPHSKPINGSGGSQEQHAQPGVSVDDFLVKCTQCHKRFTEFQSLSEHIASEHPHDKLNFEASRGSSGAVQPESDAEDEQSNLSGSRYAKSPATTTHATPSNNNNNSDLAKNHNNNNNSNSSSSKLSPMCSPGSAGPTTAAADLFAHLSHGAPPQLPPHLHAQFMAAAALAMQSARSVSSSASSPNSHHHHQQHQQQQQQQQSHLHHHQQQQQLHQQQSQQQLLPPQLPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLSGAYPCMQCTASFSSREQLEQHELLHSPTGGQPTAQNVSQTCRICHKAFANVYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRALLKRLEKSPGAAGPRRSPTDLQGPKNGAAKMTDQQSLPPLPNPMIYFAGEAQAQAAAANGAPPPFYPNYMNAALLAFPNPFMAAALDPRVHPYSIQRLLELTAAGQQQQHQQQQREEREEQEQDQHEEPETPEEPKLVMDIDESERMVPQASPQIMPEEIEPVVDMAVAPIKQEPSREPTPLPESAPPSPKSFKQEQEEPRSVEEDQPMESAQPEVSVSSPRVDTPAELRCSRCDKQFNHHTELVQHEKVLCGLIKEELEQHYHQQQQQQQHHQHLQQQQHQQQAAFALPSASEDDDEEERENDNDTEPRQDSNERKVRVRTAINEEQQQQLKQHYALNARPSRDEFRMIAARLQLDPRVVQVWFQNNRSRERKMQSYASVHTAAPAANEVPTTPVASRPTTEDQPLDLSVKRDSLTPKSDHSAVYGLPQQQAAGQPAPADFQEAINLSRKFSSSASMSPASLSPSSGASLQQSSAAAAAAAAALWPFGGPPPSPPSQHEATPAQHCSTPRGGQAFPGLPYMLPMQRLPMEALFQMRPGGEYAPNPLMNSIKMPDFRGTSLSPGGSEKRSWRDDDSRISHEDDFGNGLMPPKGRRGKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHPAASGTGPPAPSGRRGRGQSASARSQASSSTYPPHPHPHQHQHQHPHPHQHPLAAMAAFQQQQQRMHQQQQQQQRLSWPPSVPGAGVMLPPPSNQQQQRPTAPPPPLLSGAGFGQPPPQFFHHAGLLPPPAPPSGAGNVRFAAPATPPSVAPSHGGGPAFDFFNAKMLLH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603548;
90% Identity: iTF_00563802;
80% Identity: iTF_00480764;