Basic Information

Insect: Drosophila athabasca
Gene Symbol: VEZF1
Assembly: GCA_008121215.1
Location: CM017793.1:40155708-40160331[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.0012 0.082 13.1 1.1 1 23 215 237 215 237 0.96

2 20 0.021 1.4 9.3 1.7 1 23 243 265 243 265 0.97

3 20 0.032 2.2 8.7 2.4 2 23 297 318 296 318 0.97

4 20 0.0016 0.11 12.7 2.8 1 23 391 414 391 414 0.94

5 20 2 1.4e+02 3.0 1.3 2 22 422 442 421 442 0.95

6 20 0.34 23 5.4 1.5 1 23 451 473 451 473 0.97

7 20 0.0028 0.19 12.0 1.9 1 23 552 574 552 575 0.95

8 20 0.0066 0.45 10.8 0.5 2 22 583 603 582 603 0.95

9 20 0.026 1.8 9.0 0.6 1 23 612 635 612 635 0.90

10 20 1.2e-05 0.00079 19.5 1.2 2 23 658 679 657 679 0.97

11 20 9.1e-05 0.0062 16.7 1.2 1 23 686 708 686 708 0.98

12 20 0.019 1.3 9.4 0.0 2 21 735 754 734 755 0.93

13 20 0.0077 0.52 10.6 3.9 1 23 801 824 801 824 0.96

14 20 0.0043 0.3 11.4 0.5 1 23 861 884 861 884 0.96

15 20 0.00019 0.013 15.7 1.5 1 23 908 931 908 931 0.97

16 20 3.5e-06 0.00024 21.1 0.2 2 23 959 980 958 980 0.95

17 20 9.8e-05 0.0067 16.6 2.9 1 23 986 1008 986 1008 0.99

18 20 2.4e-06 0.00016 21.7 2.0 1 23 1014 1036 1014 1036 0.97

19 20 1.2e-07 8.4e-06 25.7 2.4 1 23 1042 1064 1042 1064 0.99

20 20 0.00083 0.056 13.7 0.1 1 21 1070 1090 1070 1094 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.0012	0.082	13.1	1.1	1	23	215	237	215	237	0.96
2	20	0.021	1.4	9.3	1.7	1	23	243	265	243	265	0.97
3	20	0.032	2.2	8.7	2.4	2	23	297	318	296	318	0.97
4	20	0.0016	0.11	12.7	2.8	1	23	391	414	391	414	0.94
5	20	2	1.4e+02	3.0	1.3	2	22	422	442	421	442	0.95
6	20	0.34	23	5.4	1.5	1	23	451	473	451	473	0.97
7	20	0.0028	0.19	12.0	1.9	1	23	552	574	552	575	0.95
8	20	0.0066	0.45	10.8	0.5	2	22	583	603	582	603	0.95
9	20	0.026	1.8	9.0	0.6	1	23	612	635	612	635	0.90
10	20	1.2e-05	0.00079	19.5	1.2	2	23	658	679	657	679	0.97
11	20	9.1e-05	0.0062	16.7	1.2	1	23	686	708	686	708	0.98
12	20	0.019	1.3	9.4	0.0	2	21	735	754	734	755	0.93
13	20	0.0077	0.52	10.6	3.9	1	23	801	824	801	824	0.96
14	20	0.0043	0.3	11.4	0.5	1	23	861	884	861	884	0.96
15	20	0.00019	0.013	15.7	1.5	1	23	908	931	908	931	0.97
16	20	3.5e-06	0.00024	21.1	0.2	2	23	959	980	958	980	0.95
17	20	9.8e-05	0.0067	16.6	2.9	1	23	986	1008	986	1008	0.99
18	20	2.4e-06	0.00016	21.7	2.0	1	23	1014	1036	1014	1036	0.97
19	20	1.2e-07	8.4e-06	25.7	2.4	1	23	1042	1064	1042	1064	0.99
20	20	0.00083	0.056	13.7	0.1	1	21	1070	1090	1070	1094	0.91

Sequence Information

Coding Sequence: ATGCTGCCCAGCAATATTTGCCGGACGTGTGCCCTGCAGAATACCAATTTGCTGCCCCTGTCCACGTCCTTGGACAAGTACACGAACAAAAGTTTCTATGATGTGCTCCAAGAACTAACACAGATCGATCCTCTGCTGGAGAATGCGGACGACAATCTGCCCCAGCATCTGTGTACAGATTGCTTGGACAGGCTGGAGAATGCCTACGCCTTTGTAGAGCAGGCAAGAAAGGTCAATGGAGAGCTGCTGGTGCGGCTGAGGGAATGTCTGGAGGAGAGCCCCATTGACATACCACAGCAGCAGATCAAAACGGAGATCGACATTGATGAGGAGCAAAGAGATTTCACAGATTCAGGCGAGGCACAAAGATCGTctgatgtggatgtggagtcGGCTGGCGTGTGCTCCATTGAGCTGAAATGGACTCCAGAAAGTGCCAGCGAGGAGGAAAATGCCGCCGATGCACTCTCAAACGATGAAGATGATGATGCACAGCCCTATATCTTGCGGCGAAGTCCCCGCAAAGTCAAGCAACAGGCAGACAGCGAAGAGGAGGAAGGAGTCAGTCCTTCACCCAGCAAGCGGCGTCGGGGGCGTCCTCCTGGTCTGGCCAAAAGCCAGTCAAGGAATTCCGAAGGCCGTCATGCTTGTGAGGTGTGTGGCAAAACGTTTTCCTGGTTCCGGGACATGAAGCGACATGCTCGCGTCCATTACGAGAAGGCCTCGTTCGTCTGCGATACCTGTGGCAAGGGATTCCTGCGCAAGGACAAGTACACCTTCCATCTGCGCTCCCACGAAAAGCGGGAGGCCAAGTACCAGGCCCTCCAGCTGAAGAACGAGTGGAGGTTCGCCGAGCGTTTGTACAGCTCTGGACGACTGAAGAGAATGCAGTGCAAATTGTGCGGCTTGAAATGCCAGCGAATGCAGGAGCTTCGATCCCATTTGGAGAGCCACGTCCACACGGACAGTTTGTTCAGTCTGCGAGCGGACAACGATGTGGTCAAAGAACATTTTGCCACTGGCCCATTTGACCTGGAAAAGATCAAGCAGCAAATTTGCTCGGAAATAGCGGAAGGGCAGCTGGGAAAGTACTATTCAGTGGTCAATTTCCATGGCTACGAGCTGTGCCTGAGCGATTCTGACGATGAGCCTGCCGGTGGAGAGCCACCATACCATTGTGACCTGTGCAATCTGTCGTACACTCGCAAATATCGACTGATGCGGCACACCCTGGAGGAGCACACCCAATCGCCTATTTCCCAGCGCTGCAACCTCTGCAAAGTGGGTTTTGTGTGTGCAAAGCTCTTCGAACAACACCAGCGAACCCAGTGCCAGAGCAAAGGGAAGCGCTATCGTTGCCGTAAGTGTCCAGGGAAGTTCATGTGGCTGGAGAATCTGGAGCGGCATGCCTGCTCCCATCGCAAGGAGGAGCATGCCTCGCGCTCGTTGTATCCGGAACTGGGCACTGTTTTGGATaagcaggagctggaggagaGGATCATGAGCGATGTGGCCAGCGGCTTGGAGTTGGAGCGATTCACTTCCATAACCAACGAGGCTGGCATTGAGCTCTCTCTTGAGAGCAGTGAAACGGAAACGGATTCAGAGCAGGACGAGGATGACGAGAGTTCCGAGGAAGCTGACCAGCAGCGGTACGCCTGCAACATCTGCCAGGTGGAGGTGAGGCGAAAGCATCAATTGTATGCCCACCAGTTGGAGCATCACCAGTGGGAGGAGGCTTCGCTTGTGTGTGCCCACTGTCAGGCGAGATTCGTGAGTGAAACGCTGCTGGAGCATCACTACAGGACCCTCTGCCGGAACCCACAGAAGCGTTTCCAGTGCCGAAAGTGTCCGCTACGCTTCCGCTGGCGGGAGAACCTGAAGCTGCACGCAAGTGCCTCCCATCAGCAAGTAGGACAGCCCCAAGCTGCAGAGGAACAGAGGAACGGCATCCAGACTGAGTTCGACCTCCAGTGTGGGGAGTGCAATCGCAGCTTCAAGATGCAGAAGGATCTCACGCGGCATACGCTGATGCATGCCCAGGAATCGAGCATATATCGGTGTCGCTGGTGTGCCCGCCGCTTCTACAGGAAGGCCAATCTCCTGCAGCACATCGAGCGGCATGGCATAGGAGCTAGCCAGCTGCCCTACGCGGAAGCTCTCCTCAATGCCTATGGTCAACCGAATGGCCAGAAGAGCGTGGAGTGCAAGGTGTGCAGCTTGAGCTTTCCCAGTATTGCTGCACTTCGCGTCCATCTGGAGACCATGGCGTCGGGCAGTCACCACGAACTATCGTCCCTGCAGAACTACTCGATAACCAACCAAATGGGATTCGAGCTGCACTTGGACGACTCGGAGACGGATGAGGAGGAGTCCAAGCCACCGGGCACGCCTGCTGTCTACACCTGCGGCATGTGCCAGCTCCGGTGTGTGCGAAAGTACGAGCTgcatcagcaccagcaggCCATGCACAGGCTGGAGAAGATCCCCGATGGCTGCGATCTGTGCATTTTCAAGAGTGTCTCTCCCGATCTTATCGCGCATCACAAGCGAGTGCAGTGCCACAACCGCGAGAAGCAGTTCACCTGCGCCAAATGCGGCTACAAGTTCATGTGGGAGTCCAATCTCCTGCTGCACATGCAGCTGCAACATGGCAAGACCGAAGAACAGGATGATCCACCCCTGGATGAGCCCGTGGAGCAGAAGGCTGTGTGTCCAGTCTTTCAATGCGGCCTCTGCCCAAGGAAATACAATCGCAAGGATCGGCTGACGGCCCATGTGAAGAAGTTCCACAACCCAGTGGTAGGGAGCGCTCCGAGCACCATACGGGCTGCTCCCATCCGACCAACGTCGCCCAAGGAGCCGAAACGCTTCCTATGCGCCTTCTGTGGCAAGGCTGTGAGCTCCTCCTCCAACCTCATCATCCACATGCGTCGACACACGGGCGAGAAGCCTTTCAAGTGTGACTACTGCGAAATGGCCTTCCCGCGCTCCTCCGATCTCCAGTGCCATCGACGAACGCACACCGGGGAACGGCCCCACATCTGCACCGTCTGCCAGAAGGGCTTCGCCAGATCCTACAAACTGCAGCAGCACATGCGCATCCACAACGGCGAGCGGCCCTACAAGTGCACCTACTGCGAAAAGAGCTTCACCCAGTCCAACGACCTGACACTCCACATCCGCCGCCACACGGGCGAGCGTCCCTATCAGTGCGGGGTCTGCGGCGAGCGTTTCATCCAGGGTACGGCCCTGAAGAATCATCGCCTACAGCAGGGCCACTATGACGAGGCCAGCCAAGGCGCGGCAGAGTCCGCAAGGCGCACGGTCCTAGAGCAATTTACAGTTTAG
Protein Sequence: MLPSNICRTCALQNTNLLPLSTSLDKYTNKSFYDVLQELTQIDPLLENADDNLPQHLCTDCLDRLENAYAFVEQARKVNGELLVRLRECLEESPIDIPQQQIKTEIDIDEEQRDFTDSGEAQRSSDVDVESAGVCSIELKWTPESASEEENAADALSNDEDDDAQPYILRRSPRKVKQQADSEEEEGVSPSPSKRRRGRPPGLAKSQSRNSEGRHACEVCGKTFSWFRDMKRHARVHYEKASFVCDTCGKGFLRKDKYTFHLRSHEKREAKYQALQLKNEWRFAERLYSSGRLKRMQCKLCGLKCQRMQELRSHLESHVHTDSLFSLRADNDVVKEHFATGPFDLEKIKQQICSEIAEGQLGKYYSVVNFHGYELCLSDSDDEPAGGEPPYHCDLCNLSYTRKYRLMRHTLEEHTQSPISQRCNLCKVGFVCAKLFEQHQRTQCQSKGKRYRCRKCPGKFMWLENLERHACSHRKEEHASRSLYPELGTVLDKQELEERIMSDVASGLELERFTSITNEAGIELSLESSETETDSEQDEDDESSEEADQQRYACNICQVEVRRKHQLYAHQLEHHQWEEASLVCAHCQARFVSETLLEHHYRTLCRNPQKRFQCRKCPLRFRWRENLKLHASASHQQVGQPQAAEEQRNGIQTEFDLQCGECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRKANLLQHIERHGIGASQLPYAEALLNAYGQPNGQKSVECKVCSLSFPSIAALRVHLETMASGSHHELSSLQNYSITNQMGFELHLDDSETDEEESKPPGTPAVYTCGMCQLRCVRKYELHQHQQAMHRLEKIPDGCDLCIFKSVSPDLIAHHKRVQCHNREKQFTCAKCGYKFMWESNLLLHMQLQHGKTEEQDDPPLDEPVEQKAVCPVFQCGLCPRKYNRKDRLTAHVKKFHNPVVGSAPSTIRAAPIRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHNGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHYDEASQGAAESARRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -