Dath010152.1
Basic Information
- Insect
- Drosophila athabasca
- Gene Symbol
- su(Hw)
- Assembly
- GCA_008121215.1
- Location
- CM017793.1:14620745-14624821[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00052 0.036 14.3 2.2 1 20 213 232 213 234 0.94 2 12 2.2e-06 0.00015 21.8 0.4 3 23 285 306 283 306 0.93 3 12 0.032 2.2 8.7 0.0 1 23 312 334 312 334 0.95 4 12 4.3e-07 2.9e-05 24.0 2.4 1 21 341 361 341 362 0.95 5 12 4.9e-06 0.00033 20.7 1.0 2 23 374 395 373 395 0.96 6 12 0.00022 0.015 15.5 6.3 1 23 406 428 406 428 0.99 7 12 6.4e-05 0.0043 17.2 0.9 1 23 434 456 434 456 0.97 8 12 7.4e-06 0.0005 20.1 0.7 1 23 462 484 462 484 0.98 9 12 1.2e-06 8e-05 22.6 3.0 1 23 490 512 490 512 0.98 10 12 1.3e-05 0.00088 19.3 0.5 1 23 516 538 516 538 0.97 11 12 1.6e-05 0.0011 19.0 0.1 1 21 546 566 546 570 0.92 12 12 2.1e-05 0.0015 18.7 0.4 3 23 590 611 588 611 0.96
Sequence Information
- Coding Sequence
- ATGAGCGCCGCAAAGGAGGGAAGAAAGACAGATGGCTCCTCCGAAAGGAGCAGCCGGGCCAACACGACTGTAGTGAAAATAATTGGCGTGGACAAACTATGCTTGCCCAAAGTCAAGGGACCAACGACGCGCATGAAGTTGCTCAACGACGTCGCCGCCTCTGCCAAGCCGGAGAAACGTGGTAGCCTTGGTGGCGCTCGCATTAAAATTCTCAACGAGGAGGTCTTGAGCACCCCGAAAGCCGACAAACGCAGCCCACAAAAGACAGTCAGCCCCTCGGGATCTGTCAAGATATTAAACGAGAAGCGAATGGCACCATCCACGGCGACGGCTGTGGAGACGACAAAGATCAAGACGTCCCCCaccaaacaaaagaagaaaatggaTCATTATGTGCTGCAGGCCGTAAAGGCAGAGAACAGCAAAGCAGACACCACATCCAGTGTATCCGAGGAGGACGAGAGCATTGCCTTCATCCTGGCCGACGACGATGAGATGGAACCTGTGGCGGGTCGAGCCAATGGCGAGGAGATTGTGGTTTCCAGTGCAGATGAGGACAATGAGGACGACGAAGAGGGCGATAATTCGGTGGAACGGACCGGTAGCAGCCAAGGGGCGATCAAGGAGATGGTCGAACACGTTTGCGGCAAGTGCTACAAGACGTTCCGTCGCGTGAAGAGCCTGAAGAAGCACTTGGAATTCTGTCGCTACGACAGTGGCTATCATCTGCGCAAGGCGGAGATGCTTAAAAACTTGGAGAAGATTGAAAAGGATGCTGTGGTGATGGAGAAAAAGGACAtttgcttctgctgcagcGAGAGCTACGACACCTTTCATTTGGGCCACATCAATTGCCCCGATTGTCCAAAGTCATTCAAGACGCAGACCAGCTATGAGCGTCACATCTTCATAACGCACTCGGAGTTCAACACCTATCCCTGCTCCATTTGCAATGCCAATTTGCGCAGCGCCGCCCTGCTGACGCTTCACGAGGAGCAACACAAGTCTCGTGGCAAACCGTATGCCTGTAAGATCTGCGGCAAGGACTTTACCCGCTCATATCACCTGAAGCGCCACCAGAAGTACTCGTCCTGCTCGGCCAATGAGAACGATACCATGAGCTGCAAAGTGTGCGATCGTGTCTTCTATCGCCTGGACAATCTGCGCTCGCATCTGAAGCAACATTTGGGCACACAAGTGGTGAAGAAACCAGAGTACATGTGCCACACCTGCAAGAACTGCTTCTACAGCTTGTCCACGCTGAACATTCACATACGCACCCACACTGGGGAGAAGCCCTTCGATTGCGATCTGTGTGACAAGAAGTTCTCGGCCTTGGTGGCTCTCAAGAAGCATCGACGCTACCACACAGGCGAGAAACCCTACAGCTGCACAGTGTGCAATCAATCCTTTGCCGTCAAGGAGGTGCTCAATCGCCACATGAAGCGACACACTGGAGAGCGTCCGCACAAGTGCAACGAGTGTGGCAAGAGCTTCATCCAGGCCACCCAGCTGCGCACCCATTCCAAAACCCATATACGTCCCTATGCCTGCGATTTGTGCGATGAAAAGTTCAAGACAGAGAAGCAACTCGAGCGTCACGTCAAGGAGCACACACGACAGAAGCGTGCCTCTTTCGCTTGCACTGAATGCAAGCGTACCTTCCGGACCCCGGCCTTGCTCAAGGAGCACATGGATGCCGGCGATCATTCGCCCAAACCGCAACGCGCCAAGCGCACTGCAACCAAGGTTATCGAGCGCACAGATTGCGCCATTTGTGACAAGAACTTTGACAGCACCGAGACCTTGCGCAAGCACATCCGCTCCGTTCACGAATGCGATCCGGATGACATCTTTGGTGTCGAACCGCCAGCAGCAAAGCGCAGCAAGAAGTCCAAAAAGTCTGCCGACGCAGACGAGGATACAGAACCCGTGGATCTTAATACATCGGCGGGTTCGCTCATTTCCAGCCAAACAGATGGCAATGGGGTTGTGGTCAGGGAGTTTCTGGTGGACGATGGCAATGCGCAGACCATCTTGCTAGAGAACGAAACGTACACCATTCTGCCCCTGGATGGGGCCATCAGCAGCGACCAACAGGCGCCTGGAAAAGGGGATACTGTTAAGCCGGACGCCAACAAAAGTGAGTCCAAGAAAGCGGTGGTTTCCCCGGTGGTCAAGAAGGAGCAGCGAAAATCACTGGCGGCCAGCTTGGCAGCAGCCATTGCGGACAACATGGAGGATCCGGCAAGTGACGATGATTTCAGCGGCGATGTACTCACCGAAGCCGACCTGAAGCTCAAGGAGAATGTGGCCAAGTTGATTGACATGCTGGTCGATCCGCACGTCCTCAAGAAGTACGGCTGGCCCAACACCTCCGAGGAGACAATGCTCTGCAAGGTGATCGAGAACTGTGGCCACGATCTGAGCAAGGATGAAGAGAACTACGCTGAGTTGGAATACGGCGATCGTATGCGCGAATATTGCAAGCTTCTCTTCACTGTGGTCATCCACAACGAATCCATACGGTCCCTGCTCAACAATTTCCCCATCGACGATGTCATCGAGTATGTCCTGGGCGACGAGGACCAGgacgaggaggatgaggatggcAAGCAAAAAGACAGTGATGCTGCGTCCGACCACAAGTCGGAAACCGCAGAGACCCCCGAAGCTAAGACTTAG
- Protein Sequence
- MSAAKEGRKTDGSSERSSRANTTVVKIIGVDKLCLPKVKGPTTRMKLLNDVAASAKPEKRGSLGGARIKILNEEVLSTPKADKRSPQKTVSPSGSVKILNEKRMAPSTATAVETTKIKTSPTKQKKKMDHYVLQAVKAENSKADTTSSVSEEDESIAFILADDDEMEPVAGRANGEEIVVSSADEDNEDDEEGDNSVERTGSSQGAIKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKAEMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNTYPCSICNANLRSAALLTLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHIRPYACDLCDEKFKTEKQLERHVKEHTRQKRASFACTECKRTFRTPALLKEHMDAGDHSPKPQRAKRTATKVIERTDCAICDKNFDSTETLRKHIRSVHECDPDDIFGVEPPAAKRSKKSKKSADADEDTEPVDLNTSAGSLISSQTDGNGVVVREFLVDDGNAQTILLENETYTILPLDGAISSDQQAPGKGDTVKPDANKSESKKAVVSPVVKKEQRKSLAASLAAAIADNMEDPASDDDFSGDVLTEADLKLKENVAKLIDMLVDPHVLKKYGWPNTSEETMLCKVIENCGHDLSKDEENYAELEYGDRMREYCKLLFTVVIHNESIRSLLNNFPIDDVIEYVLGDEDQDEEDEDGKQKDSDAASDHKSETAETPEAKT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00487439;
- 90% Identity
- iTF_00473938;
- 80% Identity
- -