Basic Information

Insect: Drosophila asahinai
Gene Symbol: Sp4
Assembly: GCA_008042795.1
Location: VNJZ01007920.1:68292-69512[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.00025 0.023 15.4 1.7 1 23 121 145 121 145 0.96

2 5 2.6e-08 2.4e-06 27.9 0.4 1 23 151 175 151 175 0.97

3 5 2.4e-05 0.0022 18.6 3.3 1 23 181 203 181 203 0.95

4 5 4.3e-08 3.9e-06 27.2 3.3 1 23 352 374 352 374 0.99

5 5 7.9e-05 0.0072 17.0 5.7 1 23 380 402 380 402 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.00025	0.023	15.4	1.7	1	23	121	145	121	145	0.96
2	5	2.6e-08	2.4e-06	27.9	0.4	1	23	151	175	151	175	0.97
3	5	2.4e-05	0.0022	18.6	3.3	1	23	181	203	181	203	0.95
4	5	4.3e-08	3.9e-06	27.2	3.3	1	23	352	374	352	374	0.99
5	5	7.9e-05	0.0072	17.0	5.7	1	23	380	402	380	402	0.98

Sequence Information

Coding Sequence: ATGTCACAAGTAATACCAAACACGCCCACACCCCAAATGCTGACGACATCAACGCCTATAGAACCCATGAAACCACCACCAGCGTTTCCCACGCTAGGCGTCGCTGCACATTTAAGCGAGCAGGCGTCGGACGTGATATTGAGGGCCTCCACAATTTTCGGCGATATGAAGCATCATAACGCGGTGGCGCCTTTGGATCTCGAGAACGTGCACAACGGCGTCGGAATCGGTGGTGCTGAGACTGATAACAACGGGAGCGGGGGTGAGGATGGGTCGCCGTATGGCGGCAACTCCAAGATCCGCATCATGCCCACCATTAAGCTGCTGGCGACGCCGCACGTGTCGGACCCCAAGCGCAAGTTCGTGTGCCCCTACGACAACTGTACAAAGAGCTACGGCAAGAGCTCCCACCTGCGCTCCCACCTCACCTGGCACACGGGCATCAAGCCCTTCGTCTGCAGCGAGCCCAAGTGCGGCAAGGGTTTCACGCGCTCCGACGAGCTCAACCGGCACCTGCGGACGCACACGGGCGAAAAGCCCTTCGAGTGCATCCAGTGCACCAAGAAGTTCTCGCGCAGCGACCACCTCACCAAGCACCTGGCCACCCATGACAGGCAGCTAAAAAGCAGCCCGCCAAAGCGGTCGGTGCCGAACGCCGTGCGGCTGAAGCCGTCGAAAAAGCACTCCTCGGAATCGGAACCCTCGGGGTTCCACTTCATGGCCTCGATGAGCGGCTGCGGCGATCAGAACGTGGACCAGCAGCACCAaatccaccagcagcagcaacagcagcccgCGGAGATGGTTGACTTTCAGCATAAGCCGCTGAAAATAAAGCTGGAGCGGCCGGAGCACAGTGACAAGTACCAGATCGTGGCCCCCCCGCACGCCTCTGAGAACCAGAGCCACAGCCAGCTGCCATCCTTTCTGAACCAGGCCAAGCCGGAGGTGAAATACGAGCCAGCCGACGAAATTGTAAATACACTCTCTCAGTTACCGCCGCAGGATGGCCCCGGCACCTATGGCATGCCCCAGTTCGTGCAGGACCGGCCCTTCCGCTGCCGGCAGTGCGAGAAGCGGTTTAAGCGGCAGGACGACCTGAACCGGCACATACGAACGCACACCGGCGAGAAGCCCTACGCCTGCCCGCAGTGCTGTCGCCGCTTCGTGAGGAGCGACCACTTGAAGAAGCATCAGCAAACGCATTTGAAGATACGATAG
Protein Sequence: MSQVIPNTPTPQMLTTSTPIEPMKPPPAFPTLGVAAHLSEQASDVILRASTIFGDMKHHNAVAPLDLENVHNGVGIGGAETDNNGSGGEDGSPYGGNSKIRIMPTIKLLATPHVSDPKRKFVCPYDNCTKSYGKSSHLRSHLTWHTGIKPFVCSEPKCGKGFTRSDELNRHLRTHTGEKPFECIQCTKKFSRSDHLTKHLATHDRQLKSSPPKRSVPNAVRLKPSKKHSSESEPSGFHFMASMSGCGDQNVDQQHQIHQQQQQQPAEMVDFQHKPLKIKLERPEHSDKYQIVAPPHASENQSHSQLPSFLNQAKPEVKYEPADEIVNTLSQLPPQDGPGTYGMPQFVQDRPFRCRQCEKRFKRQDDLNRHIRTHTGEKPYACPQCCRRFVRSDHLKKHQQTHLKIR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00565592;
90% Identity: iTF_00491709;
80% Identity: iTF_00606540;