Basic Information

Insect: Drosophila arizonae
Gene Symbol: zld
Assembly: GCA_001654025.1
Location: NW:12673803-12680604[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.19 11 6.2 0.1 2 23 289 311 288 311 0.93

2 6 0.0035 0.2 11.6 2.9 1 23 561 585 561 585 0.92

3 6 0.0057 0.32 11.0 4.0 2 23 1420 1442 1419 1442 0.95

4 6 0.0013 0.074 13.0 1.5 1 23 1448 1470 1448 1470 0.97

5 6 0.0013 0.071 13.0 4.4 1 23 1477 1500 1477 1500 0.92

6 6 3e-05 0.0017 18.1 6.6 1 23 1506 1528 1506 1528 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.19	11	6.2	0.1	2	23	289	311	288	311	0.93
2	6	0.0035	0.2	11.6	2.9	1	23	561	585	561	585	0.92
3	6	0.0057	0.32	11.0	4.0	2	23	1420	1442	1419	1442	0.95
4	6	0.0013	0.074	13.0	1.5	1	23	1448	1470	1448	1470	0.97
5	6	0.0013	0.071	13.0	4.4	1	23	1477	1500	1477	1500	0.92
6	6	3e-05	0.0017	18.1	6.6	1	23	1506	1528	1506	1528	0.97

Sequence Information

Coding Sequence: ATGGCGAgcataaaaagtgaaatgccGCCACTGCACGCGGCAGAGGCGCTCgctgctagcagcagcagcagcagtagcggccCAACTGATAGCGGCGGYGGAggcggcacagcagcaactgcagcagcggcagcaacaactgcagcagcggccgcagcaacagccacaacaactgcatcagcagcaactgttgctggagGCAGTGCGCCAGCAACGCCGAATGCCAATGCAACAATCAGCGCCGCCGCGGACTCCAGCGATAATCAGCCAGGCACGCCGCAGCCAACAACCCAGCAACAATCGCTGATGTCAGTGgacgcacagcagcaacagcaacagcaacaacaacagcagcagcagcagcaggcgtcgGGGATAACGCATCAGCCATATGCAACGCATCACATgtacgcagcagcagcgcaacagcaaccaccacagcagcagctctacgGCGGCCTCTACGCCAGCgatatgcagcagcaacagcagcagcagcagagttaCGCGGCCAGCAGCTACATCAACAGCTACGAGCAATtctatcagcaacagcagcagcagcaacagcagagcgCCGCTGACTATGGCGGCGCCTATGTGGACTACAGTAAAGCCTCGGCGGTGCGCTATCATCCGTATTTGCAGCAGCCAACGTCGGTGCTGCCAacggctgcggcggcagcaactgttgctgccgtcgaCGATGCCACAGCAACACCGGCGGCCGCAgtaacgacaacagcagcatctgTTGCTGCGATGAGTCCGCGCGtcgttagcagcagcagtcccaCCTCCACCTCATCGCATCTGCAGCTGagcagtgccacgcccagttcGCCGGTAGGCGGCTGCAAGCTGCAGTGCAAAAAGTGCGGCATCTTGAACACTAACGAATCGGAATTGCAGGAACACATTGCCAACGTGCACGGAGAATCGCCATACGGAAGCAGCGGCTATGCCAGCTCGCCCTACATCAAGGAGGagatgccgatgccgacgcCAACAGCGGTggccgcggcagcagcagcagcggcggcagccagCGGTGAGCTGCTCGACTTGGACTCCCAGAAGATGGTCTATCAccagcaattgctgcaacagcaacaacagcagcagcaacagcaccaccaccatcaccaccacctccaacagcagcaacaacaacatccgcagcagcagcatcagcagctccATCAACACGACGCTGTGGTTGCCGGcctgccattggcattgcccgATCCATTGCATTCGATGCAATCGATGCAGCAACGTGCGCTCCACAGTTGGGAGCAacaggccacgcccaccgagGGTCTGCCCGCCTAtatgcagccgctgctggagAAGTCGCCGCACTACTACGGCTCGCCCAAACAGTCGCCGTATCACCCATCGACGGTGGTGAAGCAGGAGTATGCATTGATCAAATCCGAATATGCCGACTCGCAGCATTATGTGGACAAATCGTTCGATCCGACGGCAGCCGAGGTGACCACCAGCCCGGCCGAGTTTCCGAGCACCACAACAACGGATGGCAATGCCGTGGGTGGCAACGCTGGCACCGCATACCGTGGCTTCGAGCCGCCCAGCTCCAGTTCGGTGCTGCCGGCGAATAGCCTCACGGCCAAGGCGGCCACCTGGAAGTCGAACGAGGCGCGTCGCCCGAAAACCTACAATTGCACCGCGTGTAACAAGTGGTTCACCAGCTCGGGCCACCTGAAGCGCCACTACAATACGACGCTGCACAAGAATGCGGTGAAGTCGAGCGGGCAGCCGGATCCGGCAACGTTGCCCATATCAGCGCATCATCATCCTGCACGTGATCCCGTTACGAAGACCAGTCGACGCGGCaatgcggcagcagcggccgcagcagcagcggcagcggcggcagcagcagcagcagctgcagcagccacacaggAACCGCCAGCAGCGGAGCCGCCCAGAAGTCCGCCGGACTATGGAGGAGGCGGTGGCGGTGTTTGTGGGGCGACGGGCGTGCAGGTGGGCGCCGCCATGTCGCAGTATTCGGCCTCGCCGTCGCCCaccgcccagcagcagcagcagcaattgattGCCAGCAATGGTTATGccaatggccacgcccactatcATGGTCATTACAatatccagcagcagcagcagcaacaagtgcaATCGACGACAAACGCTTCACCACAGCATgctaatagcaacaacaacaacagcagcagcagcaacaacaacaattccgTTTTGAACGGTCACCCAAACGGGCTAGCAGGTCCCTCCGCcccaatcaacaacaacaacaacaacaacacacaaatgcCGTCCTCCCAAATGAGGGGCCtgctgaacaacaacaacaacaaaataacaacaatcaacaacaacacaacaacaacaatagccacAACTATAAAAGTCGAGCAAATGGAGGACAGCAGCAACTCAGCAATGGTCAtggaacaggagcaggaggaggagcagcagcagcagcagcagttggaggagcaccaacagcagcagcagcagcagcaacacgtcTTGCTGCAACATCACCcactggagcagcaggagcaggtcAGTTATCTGCTGTCGCGGCCCtatcacagcagcaacagcaacagcagcaccaccatcaccaccaccagcaccaccatcaacagcagcagcaacagcaacaacagcagcagcagcagcaacagcagctcgcCGCCTATTAcctaccaccaccaccaacaactgcaaccgctgccgcagcagcagcagcagctgcagccgctgcagcagcagcagcaactggaacaggagcagcaacaccaatCGCACCACCACCAACTGTTGCAGGCAATGGATTTCTCGCGCAcccagccgctgctgccgccgccgcctatggcagcgctgctgccgcctatAACAATGGACTACAACATGCTGGCTTTGgatatgcaacagcagcacagcaatatgctgcagtgcagcagcatcagcacgccgcagcagccgttgctgcCGGTCACTATTACCACCACGCCCATCCACACGCCCATCCCcatgcacacccacacgcccATCCACACGCCCATGGCCATCCACACGCCCACCACCCACACGCACATCAATATGGACATGGAATGCACCactatgcagcagcagcagcagcagcactaccTGGCACCACAgccgctgtcgccgctgccgcagccgctgcagccgcaacaactgttgctggtggacagcaacagcagcagcagcagcaacagcagtacgGCCAGCAGCCATacgcccaacagcagcagcagcagcaacaacatcagcagctcagcagcaacagcaacacaggtgggggcggcagcagcagcagcagcagcggcggcggcggcaacatcACCACCGCCGCAcatcatcaccagcagcagcaacaacagcagcaacatcatcagcagcagcagcaacatctccaacaacagcaacagcaacatctccagcagcagcaacagcagcaacaacatcctGCCATGCtatcagcagctgccgccggtGCTGGAGCACACAATGAGCTATCACACTATTATTGGTAACGAGCCGGGCCACTACGACACCTACACGACCAGCGACGGCCACCAGATATTGCAGCTGATGCCGGCTGCCTCGCTCTTTGCGCCCTATGCACCACTGTCGCCCTATTCGGTGGCTGCGCAGCGCTCGCCGCAGGAGGGGGACTTGCCGCCGGTGCATACGCTAACGAATGCATTGCAGGCGCAGCAGgaggcgcaacagcagcagcagcagcagcaacaacaacaacaacagcagcagcagcagcaacatacaACTTTAACgctgctggccacgcccactccgtATTCGCCCACAGTGAGCAGCTCGCGTGCAACGCCAGCCCTAGAGCTTGATATGGCATCGCTCatagcacagcagcaacagcacgaCTACGAGCAATATCAGTTGCAGCAactcgaacagcagcagcagcagcaacaacagcaacatattgagcaacagcaactggagcaacaacagcagcagcagcagcagcaactcgatcagctgcagctgcaacaaactGTTGCCGTGCTGCCCAAAAAGCGACGCGCGGCCGTTGCACTttcctcaacaacaacaacaggagcaactGGAGCAGGAACAACAACTGTTGGTGGTCCGCCCAGCAAGCGAcgacgcaacagcagcatcggcTCAACATCGCCACACTCGACCACATTGCCATCGGGTCGTATCAAGTGCTTGGAGTGCGACAAGGAGTTCACCAAAAACTGTTACCTCACGCAGCACAACAAGAGCTTCCATTCCGGTGAGTATCCATATCGGTGCCAGAAGTGCGGCAAGCGCTTCCAAAGCGAGGATGTTTATACCACGCATCTGGGCCGCCATCGCACCCAAGATAAGCCGCACAAGTGCGAGCTCTGTCCAAAGCAATTCCATCACAAGACCGATTTGCGGCGACACGTGGAGGCCATCCACACGGGCCTCAAGCAGCACATGTGCGATATCTGCGAGAAGGGCTTCTGTCGCAAGGATCATCTGCGCAAGCATCTCGAGACGCACAATCGTCCACGGGTTGTTGGCaaaaaggcagcggcagctgttgctgctgcggctgctgctgctgcYGCCGCTgcaacagccaaagcagcaacggcagcagctaaaacagcagcagcagcaacagttgcagcagccacCATTGCTAGGACAACAGCTgacgatgttgctgctgacgaTGATAGTTTGCTAGACGATGATGAAGACGATAATGATGctgagcagcaccagcagcagcagcatcagcaacggcagcaactgttgctgagCGGCGAGCatcatttgattaaaaacGAATTTGTTGATATTAAGAATGAGTACGAGGAGGAGTTCACGGAGGACTTTCATATTATTGAAAAGGATATTGAAATGTATTGA
Protein Sequence: MASIKSEMPPLHAAEALAASSSSSSSGPTDSGGGGGTAATAAAAATTAAAAAATATTTASAATVAGGSAPATPNANATISAAADSSDNQPGTPQPTTQQQSLMSVDAQQQQQQQQQQQQQQQASGITHQPYATHHMYAAAAQQQPPQQQLYGGLYASDMQQQQQQQQSYAASSYINSYEQFYQQQQQQQQQSAADYGGAYVDYSKASAVRYHPYLQQPTSVLPTAAAAATVAAVDDATATPAAAVTTTAASVAAMSPRVVSSSSPTSTSSHLQLSSATPSSPVGGCKLQCKKCGILNTNESELQEHIANVHGESPYGSSGYASSPYIKEEMPMPTPTAVAAAAAAAAAASGELLDLDSQKMVYHQQLLQQQQQQQQQHHHHHHHLQQQQQQHPQQQHQQLHQHDAVVAGLPLALPDPLHSMQSMQQRALHSWEQQATPTEGLPAYMQPLLEKSPHYYGSPKQSPYHPSTVVKQEYALIKSEYADSQHYVDKSFDPTAAEVTTSPAEFPSTTTTDGNAVGGNAGTAYRGFEPPSSSSVLPANSLTAKAATWKSNEARRPKTYNCTACNKWFTSSGHLKRHYNTTLHKNAVKSSGQPDPATLPISAHHHPARDPVTKTSRRGNAAAAAAAAAAAAAAAAAAAAATQEPPAAEPPRSPPDYGGGGGGVCGATGVQVGAAMSQYSASPSPTAQQQQQQLIASNGYANGHAHYHGHYNIQQQQQQQVQSTTNASPQHANSNNNNSSSSNNNNSVLNGHPNGLAGPSAPINNNNNNNTQMPSSQMRGLLNNNNNKITTINNNTTTTIATTIKVEQMEDSSNSAMVMEQEQEEEQQQQQQLEEHQQQQQQQQHVLLQHHPLEQQEQVSYLLSRPYHSSNSNSSTTITTTSTTINSSSNSNNSSSSSNSSSPPITYHHHQQLQPLPQQQQQLQPLQQQQQLEQEQQHQSHHHQLLQAMDFSRTQPLLPPPPMAALLPPITMDYNMLALDMQQQHSNMLQCSSISTPQQPLLPVTITTTPIHTPIPMHTHTPIHTPMAIHTPTTHTHINMDMECTTMQQQQQQHYLAPQPLSPLPQPLQPQQLLLVDSNSSSSSNSSTASSHTPNSSSSSNNISSSAATATQVGAAAAAAAAAAAATSPPPHIITSSSNNSSNIISSSSNISNNSNSNISSSSNSSNNILPCYQQLPPVLEHTMSYHTIIGNEPGHYDTYTTSDGHQILQLMPAASLFAPYAPLSPYSVAAQRSPQEGDLPPVHTLTNALQAQQEAQQQQQQQQQQQQQQQQQQHTTLTLLATPTPYSPTVSSSRATPALELDMASLIAQQQQHDYEQYQLQQLEQQQQQQQQQHIEQQQLEQQQQQQQQQLDQLQLQQTVAVLPKKRRAAVALSSTTTTGATGAGTTTVGGPPSKRRRNSSIGSTSPHSTTLPSGRIKCLECDKEFTKNCYLTQHNKSFHSGEYPYRCQKCGKRFQSEDVYTTHLGRHRTQDKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHLRKHLETHNRPRVVGKKAAAAVAAAAAAAAAAATAKAATAAAKTAAAATVAAATIARTTADDVAADDDSLLDDDEDDNDAEQHQQQQHQQRQQLLLSGEHHLIKNEFVDIKNEYEEEFTEDFHIIEKDIEMY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513060;
90% Identity: iTF_00502858;
80% Identity: -