Basic Information

Insect: Drosophila arizonae
Gene Symbol: -
Assembly: GCA_001654025.1
Location: NW:13027771-13030049[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.4e-05 0.0013 18.5 2.5 1 23 406 428 406 428 0.97

2 7 2.4e-05 0.0013 18.5 0.3 1 23 434 457 434 457 0.98

3 7 0.021 1.2 9.2 1.9 1 23 463 486 463 486 0.93

4 7 1.3e-05 0.00074 19.3 2.6 1 23 526 548 526 548 0.96

5 7 0.0002 0.011 15.6 1.3 1 23 554 576 554 576 0.98

6 7 0.00014 0.0076 16.1 0.4 1 23 582 604 582 604 0.98

7 7 0.0034 0.19 11.7 5.1 1 22 610 631 610 634 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.4e-05	0.0013	18.5	2.5	1	23	406	428	406	428	0.97
2	7	2.4e-05	0.0013	18.5	0.3	1	23	434	457	434	457	0.98
3	7	0.021	1.2	9.2	1.9	1	23	463	486	463	486	0.93
4	7	1.3e-05	0.00074	19.3	2.6	1	23	526	548	526	548	0.96
5	7	0.0002	0.011	15.6	1.3	1	23	554	576	554	576	0.98
6	7	0.00014	0.0076	16.1	0.4	1	23	582	604	582	604	0.98
7	7	0.0034	0.19	11.7	5.1	1	22	610	631	610	634	0.91

Sequence Information

Coding Sequence: atgaaGTGTGCAATACAAAATTGCGCGAACAAGTTCAggtcaaaacaaaaacattctGAACAATTCAGTTTCTTCAGTTTTCCCAAAAACCCGGACGTCTTAAAAAAATGGCTTGCATTTTGCCGCAGATACAACAAAGAGAAACTGAAGGCACCACTTAAGAGCGTCATTTGCAATGAGCACTTTAAAGAGGAGGATATACAAGGAGCCTTACAGTATCAAATGGGTCTATGCAGTAAAAGAACGCTGAAACCAGGCGCCGTGCCATGCATAAATAAGAGCGATATGAGTACAGTTGAACGCGAGCGATCTGAAAGGCGAAAGAACAAAAAACTGGTCCAAGAGTTACTTGAGGAAGCGGCAGCGCGTGAAGCAGCGGAAGCCAGTGGAGCAATTGTTAAAGCTCCAGATTTTGTCAGAAACACAGGCATCGCGTCGGCTCCCGATTTCGTAATTGCAACTGGTAATGCCTTTATTCCATGTACACCGACTCCCAGTGAAAGCGATCCATTGGCAGAAGAGCAGGAAGAGCTGGAGTTGTGTGGCGTACAAAAAGTTATCCAGCAGGTTAAATGCCGCACCTGCTATGaactatttgttgttgatgaatATGCTAAAGATCTTAGTGACGAACAAAACGCAGTCATGTTATTTCACATTGAAGTTATAACTGGTATCTGGATCAAATGTAAGGAGGGCATATCGTCGTTCATGTGTTCAAACTGCGTCCAAAATCTGAGCACAGCCATACATTTTCGAGAAACCTGTATTCGAACGGAGGTAGAGCTAGCAGGAGGAGATACCATTATTAAGGACCCTGATACAGAAATTTTGAGTGCTAATGATTCAGATATAATGCAGATTAGTGAAAACTGTGATGATTTTGTTTCCATGTTTCCGGAAGAAGATCAAACCACTATTGTTGAGCCTTTTCCCTTTGAAACGACACAACAAACGGTTCAGCCAACATATCCGCCGACTGCAGATTCAAATAGTATAGCATTGGGCGCTCAAATTTATGAGGATCTTCTTAATGAATACAGGGGTAAGGACAAGACAACACGTCCACGACAGAGAAAGGCAAcaataactaaacaaaatgtGGTACGAAAACGAATACGAAAACCTCGGGATCCCAAGCCGAAACGCCCAAAGCGcacaaaagaagaaagaaatcgCATACGCCGTGAGCAAATCAGAGCCATGCCCTTGAACCACGTGTGCGACCAGTGCGGCGCCTCATTTCGGGTGAGATGCAATTTAACGATCCATATGTTGCGGCATTCGCGCACAAAGAACTATTCTTGTCCCGAGTGCCCCAAAATGTTCTACGATGCCTATATGCGAAACATGCATATACGCGTGCGGCACAAAGGCGAATTGCCATTTGAATGCAAGTATTGTAGGAAAGCATTTGGCTCGTCCAACACGCGCTATTTGCATGAAAAAAAGGTTCACGGAGCATCTCCACGTATTCACAGAAGCTCGAACAGATTGAACAAACGGATCGAACTTAAAACCTatgagcaggagcaacaaccgCAGAATGCGCTGGAACAGAGGGAAAATGTTCGTCACTTTTGTACCTATTGCAACAAGAGCTATGCGACAAAATATGCACTCAATTGGCataccaatatacatatgGGTATCACGCCTTTTAAATGCAAGCTCTGCGACATGAGCTTTCCGGATCCCCAATCGAAAAAGAAACATGAAATGAGGCATGATAGCAAACGTCCCTTCGAGTGCGACATTTGTCTAAAGGGGTTCTATGTACGCAGCAAGTTGAAAGAACACGAACGAATTCACACTGGCGAACGACCCTACAGGTGTGATGTTTGCAACGCATTCTTTCGATATAAGTTCAATTTATGCTCGCATCAATTTAGCAAAATGCATAAGGAGAATCTACAAAAGCTGAGAAAAATTGAAGTGGTTGAAGAAGATTCAAATTGA
Protein Sequence: MKCAIQNCANKFRSKQKHSEQFSFFSFPKNPDVLKKWLAFCRRYNKEKLKAPLKSVICNEHFKEEDIQGALQYQMGLCSKRTLKPGAVPCINKSDMSTVERERSERRKNKKLVQELLEEAAAREAAEASGAIVKAPDFVRNTGIASAPDFVIATGNAFIPCTPTPSESDPLAEEQEELELCGVQKVIQQVKCRTCYELFVVDEYAKDLSDEQNAVMLFHIEVITGIWIKCKEGISSFMCSNCVQNLSTAIHFRETCIRTEVELAGGDTIIKDPDTEILSANDSDIMQISENCDDFVSMFPEEDQTTIVEPFPFETTQQTVQPTYPPTADSNSIALGAQIYEDLLNEYRGKDKTTRPRQRKATITKQNVVRKRIRKPRDPKPKRPKRTKEERNRIRREQIRAMPLNHVCDQCGASFRVRCNLTIHMLRHSRTKNYSCPECPKMFYDAYMRNMHIRVRHKGELPFECKYCRKAFGSSNTRYLHEKKVHGASPRIHRSSNRLNKRIELKTYEQEQQPQNALEQRENVRHFCTYCNKSYATKYALNWHTNIHMGITPFKCKLCDMSFPDPQSKKKHEMRHDSKRPFECDICLKGFYVRSKLKEHERIHTGERPYRCDVCNAFFRYKFNLCSHQFSKMHKENLQKLRKIEVVEEDSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516527;
90% Identity: iTF_00551844;
80% Identity: iTF_00479513;