Basic Information

Insect: Drosophila arizonae
Gene Symbol: L
Assembly: GCA_001654025.1
Location: NW:13320638-13332130[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 8.5e-06 0.00048 19.9 2.9 1 23 151 173 151 173 0.98

2 17 0.29 16 5.6 6.2 1 23 179 201 179 201 0.97

3 17 1.4e-07 7.9e-06 25.5 3.2 1 23 207 229 207 229 0.99

4 17 1e-05 0.00058 19.6 0.4 1 23 235 257 235 257 0.99

5 17 0.011 0.64 10.0 0.2 2 23 338 362 337 362 0.93

6 17 0.00025 0.014 15.2 0.2 2 23 391 413 390 413 0.96

7 17 0.051 2.9 8.0 0.7 1 23 487 509 487 509 0.97

8 17 0.06 3.4 7.8 0.3 2 23 517 538 516 538 0.91

9 17 0.017 0.96 9.5 1.2 3 23 549 571 546 571 0.86

10 17 2.7 1.5e+02 2.6 1.0 2 23 607 629 606 629 0.95

11 17 0.0021 0.12 12.3 1.1 1 23 674 697 674 697 0.97

12 17 0.0054 0.3 11.1 1.6 2 23 874 896 873 896 0.96

13 17 0.095 5.4 7.1 0.1 1 23 902 924 902 924 0.92

14 17 0.21 12 6.1 0.6 2 23 932 953 931 953 0.96

15 17 0.26 15 5.8 1.3 1 23 1050 1072 1050 1072 0.94

16 17 0.016 0.93 9.5 0.0 1 23 1082 1104 1082 1104 0.96

17 17 0.00018 0.01 15.7 1.2 1 23 1109 1131 1109 1131 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	8.5e-06	0.00048	19.9	2.9	1	23	151	173	151	173	0.98
2	17	0.29	16	5.6	6.2	1	23	179	201	179	201	0.97
3	17	1.4e-07	7.9e-06	25.5	3.2	1	23	207	229	207	229	0.99
4	17	1e-05	0.00058	19.6	0.4	1	23	235	257	235	257	0.99
5	17	0.011	0.64	10.0	0.2	2	23	338	362	337	362	0.93
6	17	0.00025	0.014	15.2	0.2	2	23	391	413	390	413	0.96
7	17	0.051	2.9	8.0	0.7	1	23	487	509	487	509	0.97
8	17	0.06	3.4	7.8	0.3	2	23	517	538	516	538	0.91
9	17	0.017	0.96	9.5	1.2	3	23	549	571	546	571	0.86
10	17	2.7	1.5e+02	2.6	1.0	2	23	607	629	606	629	0.95
11	17	0.0021	0.12	12.3	1.1	1	23	674	697	674	697	0.97
12	17	0.0054	0.3	11.1	1.6	2	23	874	896	873	896	0.96
13	17	0.095	5.4	7.1	0.1	1	23	902	924	902	924	0.92
14	17	0.21	12	6.1	0.6	2	23	932	953	931	953	0.96
15	17	0.26	15	5.8	1.3	1	23	1050	1072	1050	1072	0.94
16	17	0.016	0.93	9.5	0.0	1	23	1082	1104	1082	1104	0.96
17	17	0.00018	0.01	15.7	1.2	1	23	1109	1131	1109	1131	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTagagaatttaattgaaaagattCAAGCGACCAAGGAGATAACTAATAACGATATGTACAGCACGCACACTTCGTCGAGCTATTCGCCCAGCATCTCGGATGGAACTTTGACGCCCAActcacagctgcagcagccgcagcagcagcagcagcagtcgcagtcgcagcagcagcagtcgtcgGCCGGTTCGGAGGAGcaggagctgagcAAGCCGAAGCGAGCGGCACAtttgcatcatcatcatcatcatcattatcatcatcagcaggcGCTGAAAATAGCGAACAAGCTGCGCAAAATCAATAAGGATGCAAAGCTGGCTGcaggacaaggacaaggacatgGYACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCACGGCTCGGCTACCTGAAGCATCACGTGCAGaGTCATGCCGAGCATTTGCCTTTCAAGTGCGAGTACTGCGCAAAGCTGTTCAAGCACAAACGCTCCCGGGATCGCCATAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGTGATCATCTGAAGATCCACATGAAGACGCACGACATACAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCCGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCCGCAATCCTCGCAGCTGGCGGCAATCCCAATGCACTCAATTACAGTCCACGCTCCACGGGCTCCGCCTCGATCTCGAGCAATGGGAGCCTGCATAAGCGACGCTATGCCTTGGCGCTGGCCTCCGACAGCAGTCCCAGTCGGCTGGAGTTTCCCAAGCGGGCGCGTGGCCAGCtggcggccacgcccacggccACAACGATAGCCACGCCGACGCCCACGccgctgctgcgctgcagctACTGCCCCAAGGCAACGGAGTTCAGCAGCCTCGAGCAGCTCAACGCGCATCTGCAGAGCACacacgagcagcagccgcagccgcagccgcagccgcagcagcagcagcagtcgaagGAGTCGGATGGCCAGACGAATGGCTTCCAGTTGAGCTGCGAATATTGCACGATGAAGTTTGTGAATATCGCTGCGCTCTTCCAGCACATGAGAGTCACGCACTTGGATCGCCTGAGCAGCCCCAATTCCTATTACGAGCACTTCCATCGCCTGGGCTCGCCGCAGTCGAAGCTGAAGTCAGATCTGGCGCCAACGGAGAAGCCCGAGCAGGAGCTGCCCACCGATctgagcagcaacaagcgcCGCCCGCTGATCTCACccacgcagcaacagcagcagcaacagcagccggcgcCAGCTCCACCGCCGCCTCCTGGCATCTTCTTCTGCAATCAGTGCAACGCCGGCCTGCCGGACTTTGAGAGCTTTCGCAATCATCTGAAGAGCCACATCGCCGAGGGCATGCAGCTGATCTGTCCGCACTGCGGCCTCAGTCTGCCCGAGCAGTGCGAGTACGAGCGCCATGTGGTCGCCCATTTCCTGATCAGCAGCTCCGAGTTCAattgctgcagcgccagctgcgGCAAGTCCTATGCCAAGGCGGAGGAGCTGCATCAGCATCTGCTGGCCGAGCACGTCCAGACGATGCTGAAGTGTGTCCTGTGCTCGGAGCTCTGCGAGAATCGCATGTCCATGCAGCTGCACCTGGCCTGCGCCCATAGCCAGGAGTCGAagctgctgcgctgcagcgCCTGCCTGGAGCTCTTCCGCAACGATGGCGACTTCCATGTGCATGTGAAGACACGCCATCAGCTGGGCAACCAGGGCACTCTGCCCGGTAATCCTCCTGCGCCGGCCAATCCGCTGCAGTGCATGTTCTGCCGCGCCGTCTGCTCCTCGGAGCTGGAGatgcatttccatttggcgGCGCATGCGCGACAGTTCCGCTGCCCCAGCTGCCCGGAGACCTTCCATGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCACGGCGGCATCAAGGACAAGGAGTCGCCGGTTCCGGGCGGCATGGGCAGCTTGTATGTGaatgcgctgctgccgccactggcagcggctgctgctgccgctgccgcggcaagcaatgccagcaacaacaacaacaacaacaataataataatattgattacAATGTCGCCTTCAAGGGTCTCTTTGGCGGCGGCAATCCGCCGAGCAAGTTCTACAACAGCCCGCTCCAGGTGGACACCAAGCAGAGTCCGCATCCTGCTCTCATGTACGGCCTGAGCCAGCGCTACTTGATGGAGATGTACGCCGCCAAGGCCAATTCGCCAGCCAATGCCAGCGCCGGAGCGGAGCTGCCCACGCCGCAGGccgcgtcagcagcagcagcagcagcagcgagcggcagcaacagcagcggcagcaacaacaacaacagctacagctgcggCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCCGAGCTCCATTCGCATCGTAAGCTCGCCCACAATCTGAAGACGGGCGTCAGCCTGCGCTGCGCGTACTGCTCCGGGAACTACAagagccgagccgagctggagcagcacatGAAGAGCTGCCACAACTCGAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTCCCCTCGCCCGCCATTCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGCCAGTCCGGCAAGTGCGCCCACTgcggccagcagctggagcacgTGGCCGCCTTCCGTGCCCATCTCAGCGAGCATGGCAACGATGGCAATCTGCCCATGGCCTGCATCTGCTGCCGCCAGACGCTGCACTCGGAATTCGAGCTGAGTCTGCATGCCAAATTCCACACCAAGTCGCCCAGTTGCAACAGCCTGCAGGAGCCCGTCTGCGCCCTCTGCCTGGAGCCGCTGCCGGGGGCGGGGGAGACGGCCAAGCTGTGCGACAAATGCTGCCGCAAGCACAATCTGAATGGCAAGCGCAAGGAGCAGGTGCAGCCCACGGCCATCGCTGCCcctgcagccgccgcagctggCGCCTATCTGGAGCATCGCTGCAATCTGTGCAAGATGATCTTGCCCCATGCCCAGAAGCTGCAGGAGCATCTCGTCGAGCACACCTTCGCGGGCACCGAGCAGCGTGGCTACAATTGCTACATCTGCTCGGCTGTGTTCACGGCGCCCGCTGGCCTGCTCGCCCACATAGCGGAGCACGGCACGCGTCCGTACGACTGCAACTTGTGCCCGGAGAAATTCTACTTCCGTGCCGAGCTGGAGCATCATCAGCGAGCGCACGAACTGCACGCTCAGccggcagcaatggcagcggcagcagcagccgcagcagcagcagcaggagcaggagcagcagcaacacgtgCTCCTAAGCAGGAGGCGCACAGCTCGACGGCCAGTTCTCCACTGACGCTCAGTCCCAGTCATGTCAAGCAGGAGCTATACGAATCGGAGCCAGCGAATTCGCCCAACGCCGCGGAGCTGCCTCCTgcgcagcaggaggaggaggagtacaTTGAGGTGGAGCAAATGCCGCAGGAGACGCTGCGAACTGGCGAACTACTAAGCACCGAGcgttccagcagcagcgcctaa
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQLQQPQQQQQQSQSQQQQSSAGSEEQELSKPKRAAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLAATPTATTIATPTPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQPQPQPQPQQQQQSKESDGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFHRLGSPQSKLKSDLAPTEKPEQELPTDLSSNKRRPLISPTQQQQQQQQPAPAPPPPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDGDFHVHVKTRHQLGNQGTLPGNPPAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVPGGMGSLYVNALLPPLAAAAAAAAAASNASNNNNNNNNNNIDYNVAFKGLFGGGNPPSKFYNSPLQVDTKQSPHPALMYGLSQRYLMEMYAAKANSPANASAGAELPTPQAASAAAAAAASGSNSSGSNNNNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLSEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQVQPTAIAAPAAAAAGAYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPAGLLAHIAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELHAQPAAMAAAAAAAAAAAGAGAAATRAPKQEAHSSTASSPLTLSPSHVKQELYESEPANSPNAAELPPAQQEEEEYIEVEQMPQETLRTGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00549782;
90% Identity: iTF_00502755;
80% Identity: -