Basic Information

Insect: Drosophila arizonae
Gene Symbol: rn
Assembly: GCA_001654025.1
Location: NW:4811875-4858756[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 4.5e-06 0.00025 20.7 0.4 1 23 471 493 471 493 0.98

2 6 1.6e-06 9e-05 22.2 1.6 1 23 500 522 500 522 0.99

3 6 1.3e-07 7.5e-06 25.6 3.9 1 23 528 550 528 550 0.99

4 6 0.0019 0.11 12.5 4.4 1 21 556 578 556 580 0.93

5 6 0.0037 0.21 11.6 2.1 1 20 586 605 586 608 0.93

6 6 1.2e-06 6.6e-05 22.6 3.1 1 23 617 639 617 639 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	4.5e-06	0.00025	20.7	0.4	1	23	471	493	471	493	0.98
2	6	1.6e-06	9e-05	22.2	1.6	1	23	500	522	500	522	0.99
3	6	1.3e-07	7.5e-06	25.6	3.9	1	23	528	550	528	550	0.99
4	6	0.0019	0.11	12.5	4.4	1	21	556	578	556	580	0.93
5	6	0.0037	0.21	11.6	2.1	1	20	586	605	586	608	0.93
6	6	1.2e-06	6.6e-05	22.6	3.1	1	23	617	639	617	639	0.97

Sequence Information

Coding Sequence: ATGATTATGCATGGTACCTGGTACAAAGGACCACAGCTGGCGCATCATCCACACACCGACTACCATCAGTTCCGATCGTATCCATCGTTCGTAGTGACGCCCTATCACGAGGGTCATGCGGCCACGCCCTGCCCACCAACGCCCTCAACGccctgccacagcagcagcagcagcagcagcaaccatgGACTCGGACTTGgtcttggacttggacttggtgTTGGAGTTGGACTTGGCCAGAGTGCAGCAGCCGAGCCGGCGCCAATAATTGTCGAGGGCACATTCGCTgcggccgccgctgccgccgctgctgcagctgcagcgcatcccgttgcaacagctgcaactgccgCCAGAGCTGCGCCCAGTCCGGCGATCAAGATCGAGCAGGTGTTCGGGGAGCAGACATCGGGGCACTCAACGCTGGTCGAGGACTATGCCCTGAGCCTCGACTGTCCCGTGGAGCATCAGTTTCGGAAACcccaaaataacaacaacaacagcaacaacaacaacaacaacaacggcaacggctacGCCTGGCCAACGGGCAACGAAGTCgtcaacagccacaacaacaatcagcacAATTCACACGCAGCAAACGCTGCAGGACCTGGACAAGGACTCTCGCCAGCGACGCCGCCAACGCCGCCCGTGGACGCCAGCCAGGCCGGTTccgcaattaatttgaatcCACCCGCaacacagacgcacacgcaGAGCCGTGCAAACTACGCCAATTCCGTAAAGTCGCCACCGGAAACAGGCAGCGCGCAGCCATCAACGGCTGCCGCCACCTGCAAaacaaacgacaacaacaacagcagcaacaacaaccacaacaacaacagcaacgcaactgctgccgctgtggcagccgctgcagccgccgccgccgctgtcaACATGCCGATCGGCGGCGTCCAGGGCCAGAATCCCACCCAGGGCCTGGTCCATTGGATGAGCGCCGTGATGGCCGAGCACATGACCGGACAGACGCATCACGATCCCAGCACTGCGGTCGGCATGCACTACATGTGGAATGGCAACGTCGATGCCAAAATGAACGATCACCACCATCACAATAATCTGCAAAAAGGTCACTTTCTGGATGACAATCGTCTGGAGCACCATGCGGCGGTCGCCGGACAAGGCAGCCTGGGACTTGGCAGCGCTGTCAACGGTTCCGGCTCCGGGCCGGGAGGCGGCAACTCCAGTTTGGCTGGCGGTTCGCATCATGGCAATCACGTGTCGgcggccgctgcagccgcGGCGCATCATCACAACAATGCGGTGGCAGCTGCCTCGGCGGCGGCACTGCTCGTCGTCCCGCAGCCCATCAATGCCAGCAAAATGGGCGGGCCGGGACCGGCCGGCCACGCACCGGCCGGAGGCAGTGGACGAAAGTATCAATGCAAAATGTGCCCGCAGATCTTCAGCTCGAAGGCGGACCTGCAGCTGCACACGCAGATCCACATGCGAGAGGCGAAGCCCTACAAGTGCACGCAGTGCTCGAAGGCATTCGCCAACTCGTCGTATCTGTCGCAGCACACCCGCATTCATCTGGGCATTAAGCCGTACCGCTGCGAGATATGCCAGCGCAAGTTCACGCAACTGTcgcacctgcagcagcacataCGCACCCACACGGGCGACAAGCCGTACAAGTGCCGGCATCCCGGCTGCCAGAAGGCCTTCTCCCAGCTGTCGAATCTGCAGTCGCACTCGCGCTGCCATCAGACGGACAAGCCGTTCAAGTGCAACTCGTGCTACAAGTGCTTCTCGGACGAGCCATCGCTGCTGGAGCACATACCCAAGCACAAGGAGTCCAAGCATCTGAAGACGCACATCTGCCAGTACTGCGGCAAGTCCTACACCCAGGAGACATACCTGACCAAGCACATGCAGAAGCATGCGGAGCGCACGGACAAGCGGCCGCCCATTGTGCCCGGCAGTGCAGCAGCCGTggccgctgcagccgccgctgcggccgctgccacacccactgcagcaggcagcaacgcacagcagcagcaacagcagcaacagcagcagcagcaacaacagcagcatcagcgcaATAATCTGGTGTTGCCGCCCGTTTCGATAGCGCCCAGCGAGAACAGTTACTGGCCCAAGGTAAGTCCGGACTCTGCAGCTGCGGCCAATGCCATGGAGGTGatgcaccagcaacagcaacagcagcagcaacaacagcaacaacagcagcagcagcagcagcaacaacagcagcagcaacagcagcagcaacaacaacagcaacaacagccgcatcTGCATCATACGCAGCTCGGCGTTCCGCCGCAGCAACACGGcccgccacagcagcagcaacaaccgcagcaccaccacccacagcaacagcagcagcagcagccaccgccCCAGCACAGCATGGAGGCGCACTACGCTCAACCCACAGCGGCCAACAGCAACCAAAGCAATGGCCATGCGCcggagcagctgcagtcgcacCATCGCATCATGCCCGATCCGGGGCGCGAGGATATAGcagccacgcccagcgccGTGGGGCCGTACGATGCGGCATCTATAACGAAGACCAGCAGCAACTCGGCCTTTACGCCGATCAACTCGATGCCGCCGCACTTGAATTCGCTGAGCCACCATCCGATGGCACAGCGTCCCTATCTCTACGATGCCATCAGTTTTCCCAACAAGAACGTCAACCAGAACAATGCCAATGCGTTTCCCAACCAGCTGATCTCGCTGCATCAGATCCGCAACTATGCGCATCAGCCAGCGGGCTTGATGGCCGGCGAGCATCTGCTAGGCGTAAGCGTCGGCCCTGGCAAGGACAAGGGATAG
Protein Sequence: MIMHGTWYKGPQLAHHPHTDYHQFRSYPSFVVTPYHEGHAATPCPPTPSTPCHSSSSSSSNHGLGLGLGLGLGVGVGLGQSAAAEPAPIIVEGTFAAAAAAAAAAAAAHPVATAATAARAAPSPAIKIEQVFGEQTSGHSTLVEDYALSLDCPVEHQFRKPQNNNNNSNNNNNNNGNGYAWPTGNEVVNSHNNNQHNSHAANAAGPGQGLSPATPPTPPVDASQAGSAINLNPPATQTHTQSRANYANSVKSPPETGSAQPSTAAATCKTNDNNNSSNNNHNNNSNATAAAVAAAAAAAAAVNMPIGGVQGQNPTQGLVHWMSAVMAEHMTGQTHHDPSTAVGMHYMWNGNVDAKMNDHHHHNNLQKGHFLDDNRLEHHAAVAGQGSLGLGSAVNGSGSGPGGGNSSLAGGSHHGNHVSAAAAAAAHHHNNAVAAASAAALLVVPQPINASKMGGPGPAGHAPAGGSGRKYQCKMCPQIFSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHAERTDKRPPIVPGSAAAVAAAAAAAAAATPTAAGSNAQQQQQQQQQQQQQQQHQRNNLVLPPVSIAPSENSYWPKVSPDSAAAANAMEVMHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPHLHHTQLGVPPQQHGPPQQQQQPQHHHPQQQQQQQPPPQHSMEAHYAQPTAANSNQSNGHAPEQLQSHHRIMPDPGREDIAATPSAVGPYDAASITKTSSNSAFTPINSMPPHLNSLSHHPMAQRPYLYDAISFPNKNVNQNNANAFPNQLISLHQIRNYAHQPAGLMAGEHLLGVSVGPGKDKG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00520121;
90% Identity: iTF_00520121;
80% Identity: -